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  • 1
    Online Resource
    Online Resource
    Enhanced Sub‐Terahertz Microscopy based on Broadband Airy Beam
    Wiley ; 2022
    In:  Advanced Materials Technologies Vol. 7, No. 5 ( 2022-05)
    Details
    In: Advanced Materials Technologies, Wiley, Vol. 7, No. 5 ( 2022-05)
    Abstract: Non‐diffraction electromagnetic beams such as Airy beams attract wide exploration in various disciplines owing to its fascinating features and great potential of applications. Although generation and applications of Airy beams are actively studied in the optical regime, applications of Airy beams in the THz or sub‐THz domain are rarely explored. This work proposes a new microscopic technique leveraging a sub‐THz broadband non‐diffraction Airy beam as the illumination beam to improve the image quality, which is named as enhanced sub‐THz microscopy (ESTM). The effectiveness of the ESTM is validated by a metallic sample, which shows that applying broadband measured information can render a better image quality than only using single‐frequency information. By blocking the sample using a scattering obstacle, it is demonstrated that the self‐reconstruction property of the Airy beam can efficiently suppress the distortion induced by the obstacle and good images can still be obtained. In addition, it is shown that the image quality applying a broadband Airy beam is superior to that of non‐diffraction quasi‐Bessel beams and other conventionally used illumination beams for microscopic technique.
    Type of Medium: Online Resource
    ISSN: 2365-709X , 2365-709X
    URL: Issue
    URL: Article
    DOI: 10.1002/admt.v7.5
    DOI: 10.1002/admt.202100985
    Language: English
    Publisher: Wiley
    Publication Date: 2022
    detail.hit.zdb_id: 2850995-X
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  • 2
    Online Resource
    Online Resource
    Controlled transurethral resection and incision of the bladder neck to treat female primary bladder neck obstruction: Description of a novel surgical procedure
    Wiley ; 2016
    In:  International Journal of Urology Vol. 23, No. 6 ( 2016-06), p. 491-495
    Details
    In: International Journal of Urology, Wiley, Vol. 23, No. 6 ( 2016-06), p. 491-495
    Abstract: To investigate the efficacy and complications of controlled transurethral resection and incision of the bladder neck to treat female primary bladder neck obstruction. Methods A total of 59 patients who were diagnosed with female primary bladder neck obstruction by urodynamic examination underwent surgical procedures at Urological Institute of the People's Liberation Army, First Affiliated Hospital of Third Military Medical University, Chongqing, China, between March 2010 and March 2014. For all patients, neurogenic, anatomical and dysfunctional voiding causes of bladder outlet obstruction had been excluded. Perioperative and follow‐up data, including operative time, maximum urine flow rate, residual urine volume, International Prostate Symptom Score and Quality of Life Score, were prospectively investigated. Results All of the operations were completed uneventful. The median operative time was 15 ± 8 min (range 10–22 min). No massive hemorrhage or infection was reported. Follow‐up data were available for 59, 59, and 57 of the patients at 1, 6 and 12 months postoperatively, respectively. The mean maximum urine flow rate increased from 7.2 ± 3.9 mL/s preoperatively to 26.1 ± 5.2 mL/s postoperatively. The mean residual urine volume decreased from 162 ± 75 to 20 ± 7 mL. The mean International Prostate Symptom Score decreased from 24.5 ± 7.2 to 5.5 ± 3.6. The mean Quality of Life Score decreased from 5.4 ± 1.7 to 1.9 ± 1.1. All of the differences between the preoperative and postoperative values were significant ( P 〈 0.001). Conclusions The novel technique described here shortens the length of the urethra to 2.5 cm, which both released the obstruction and maintained continence. The results of the present preliminary study show that this method represents a safe and effective treatment for female primary bladder neck obstruction.
    Type of Medium: Online Resource
    ISSN: 0919-8172 , 1442-2042
    URL: Issue
    URL: Article
    DOI: 10.1111/iju.2016.23.issue-6
    DOI: 10.1111/iju.13085
    Language: English
    Publisher: Wiley
    Publication Date: 2016
    detail.hit.zdb_id: 2009793-1
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  • 3
    Online Resource
    Online Resource
    Design of thermal conductive polymer composites with precisely controlling graphene nanoplatelets at the interface of polypropylene and high melt strength polypropylene via elongation flow
    Wiley ; 2023
    In:  Polymers for Advanced Technologies Vol. 34, No. 7 ( 2023-07), p. 2142-2152
    Details
    In: Polymers for Advanced Technologies, Wiley, Vol. 34, No. 7 ( 2023-07), p. 2142-2152
    Abstract: The migration and selective localization of graphene nanoplatelets (GNPs) in a polypropylene/high melt strength polypropylene (PP/HMSPP) blend under elongational and shear forces are studied. The effects of elongational flow upon the elongational rheology, X‐ray diffraction patterns, thermal properties, and mechanical properties are investigated. The results show that the elongational viscosity and melt strength of HMSPP are higher than those of PP under elongational flow, whereby HMSPP shows elongational strain hardening behavior, and the migrating of GNPs from the PP to the HMSPP phase is hindered. As a result, the GNPs are constrained to remain at the interface between the two phases. In addition, the elongational force can exfoliate GNPs more effectively, and the orientation of GNPs along the phase interface will reduce the migration rate of GNPs at the interface, while precisely controlling the location of the GNPs at the phase interface. Thus, more thermal conductivity pathways are constructed and, hence, the thermal conductivity of the PP/HMSPP/GNPs composite prepared under elongational flow is higher than that prepared under shear flow. The present work provides a new method for the preparation of highly thermally conductive polymer composites.
    Type of Medium: Online Resource
    ISSN: 1042-7147 , 1099-1581
    URL: Issue
    URL: Article
    DOI: 10.1002/pat.v34.7
    DOI: 10.1002/pat.6034
    RVK:
    VA 6586
    Language: English
    Publisher: Wiley
    Publication Date: 2023
    detail.hit.zdb_id: 1481102-9
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  • 4
    Online Resource
    Online Resource
    Simvastatin alleviated diabetes mellitus‐induced erectile dysfunction in rats by enhancing AMPK pathway‐induced autophagy
    Wiley ; 2020
    In:  Andrology Vol. 8, No. 3 ( 2020-05), p. 780-792
    Details
    In: Andrology, Wiley, Vol. 8, No. 3 ( 2020-05), p. 780-792
    Abstract: Diabetes mellitus‐induced erectile dysfunction is a common diabetic complication, and new therapeutics and the pathogenesis of diabetes mellitus‐induced erectile dysfunction need to be investigated. Objectives The aim was to investigate the pathogenesis of diabetes mellitus‐induced erectile dysfunction and the pharmacological mechanism of simvastatin treatment in diabetes mellitus‐induced erectile dysfunction model rats. Materials and methods A total of 86 male Sprague Dawley rats aged 8 weeks old were used in this study. The rats were divided into three groups: control (normal), diabetes mellitus‐induced erectile dysfunction (streptozotocin‐injected), and diabetes mellitus‐induced erectile dysfunction + simvastatin (sim). Each group was subdivided into two subgroups for in vitro and in vivo analyses. A bioinformatics method was used to detect differences in gene expression in the corpus cavernosum between normal and diabetes mellitus‐induced erectile dysfunction rats. Erectile function was measured by a cavernous nerve electrostimulation test. Corpus cavernosum fibrosis was assessed by Masson staining and Western blotting. Immunofluorescence and Western blotting were performed to explore the differential expression of autophagy‐related genes and the AMPK‐SKP2‐CARM1 pathway genes in rat cavernous smooth muscle cells and the corpus cavernosum. The autophagosomes of the corpus cavernosum tissue were observed by transmission electron microscopy. Results Autophagy‐related genes and pathways (the AMPK and FoxO pathway) were identified by bioinformatics analysis and confirmed at the protein level. Simvastatin, an AMPK agonist, was used to treat diabetes mellitus‐induced erectile dysfunction rats for 8 weeks, demonstrating that erectile function was improved for 80.5% ( P   〈  .05) of rats. Corpus cavernosum fibrosis was alleviated ( P   〈  .05), and autophagy was further enhanced ( P   〈  .05); these results might be partially caused by AMPK‐SKP2‐CARM1 pathway activation ( P   〈  .05). Discussion and conclusion Simvastatin could enhance protective autophagy by activating the AMPK‐SKP2‐CARM1 pathway to improve erectile function in diabetes mellitus‐induced erectile dysfunction rats.
    Type of Medium: Online Resource
    ISSN: 2047-2919 , 2047-2927
    URL: Issue
    URL: Article
    DOI: 10.1111/andr.v8.3
    DOI: 10.1111/andr.12758
    Language: English
    Publisher: Wiley
    Publication Date: 2020
    detail.hit.zdb_id: 2693844-3
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  • 5
    Online Resource
    Online Resource
    Round ligament suspending treatment in orthotopic ileal‐neobladder after radical cystectomy in women: a single‐centre prospective randomised trial
    Wiley ; 2021
    In:  BJU International Vol. 128, No. 2 ( 2021-08), p. 187-195
    Details
    In: BJU International, Wiley, Vol. 128, No. 2 ( 2021-08), p. 187-195
    Abstract: To compare the occurrence of emptying dysfunction between surgical techniques for orthotopic neobladder suspended with round ligament (rONB) and the standard procedure (sONB). Patients and Methods A prospective randomised controlled trial was performed in a single centre of female patients undergoing creation of an ONB using rONB or sONB. Patients were followed for ≥24 months after ONB. The primary endpoints were significant post‐void residual urine volume (sPVR) and need for clean intermittent catheterisation (CIC) at 24 months postoperatively. The secondary endpoints included early and late complications, urodynamic profile, and ONB continence. Results Between January 2011 and October 2017, the trial enrolled 85 patients, of whom 82 were randomised. A total of 41 patients had a rONB and 41 a sONB. At 24 months, 17 of the 37 patients with a sONB and nine of the 39 patients with a rONB had a sPVR. The cumulative risk of a sPVR was significantly lower in the rONB group (23.1%) vs the sONB group (45.9%) (hazard ratio [HR] 0.43, 95% confidence interval [CI] , 0.19–0.96; P  = 0.040). In all, 15 of the 37 patients with a sONB and four of the 39 patients with a rONB needed CIC. The cumulative risk of requiring CIC was significantly lower in the rONB group (10.3%) vs the sONB group (40.5%) (HR 0.22, 95% CI 0.07–0.67; P  = 0.008) at 24 months. Multivariable Cox regression analysis also showed that the rONB type was an independently protective factor for sPVR and CIC. The rates of early (0–90 days) and late complication ( 〉 90 days) were 54.1% and 13.5% in the sONB group, and 64.1% and 10.3% in the rONB group, respectively. There were no significant differences in complications, urodynamic profile or ONB continence. A major limitation is the small sample size at a single centre. Conclusion Posterior support with round ligament for an ONB significantly improved the emptying of the ONB and resulted in a reduced need for CIC. The surgical modification is a feasible and safe technique without additional complication‐related surgeries.
    Type of Medium: Online Resource
    ISSN: 1464-4096 , 1464-410X
    URL: Issue
    URL: Article
    DOI: 10.1111/bju.v128.2
    DOI: 10.1111/bju.15306
    Language: English
    Publisher: Wiley
    Publication Date: 2021
    detail.hit.zdb_id: 2019983-1
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  • 6
    Online Resource
    Online Resource
    Chemical irritation of the prostate sensitizes P 2 X 3 receptor-mediated responses in rat dorsal root ganglion neurons : Prostate P 2 X 3 Receptor-Mediated Responses
    Wiley ; 2011
    In:  Neurourology and Urodynamics Vol. 30, No. 4 ( 2011-04), p. 612-618
    Details
    In: Neurourology and Urodynamics, Wiley, Vol. 30, No. 4 ( 2011-04), p. 612-618
    Type of Medium: Online Resource
    ISSN: 0733-2467
    URL: Article
    DOI: 10.1002/nau.21060
    Language: English
    Publisher: Wiley
    Publication Date: 2011
    detail.hit.zdb_id: 1500793-5
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  • 7
    Online Resource
    Online Resource
    The Sulfinylsulfonation of alkynes for β‐Sulfinyl alkenylsulfone
    Wiley ; 2022
    In:  Chemistry – An Asian Journal Vol. 17, No. 14 ( 2022-07-15)
    Details
    In: Chemistry – An Asian Journal, Wiley, Vol. 17, No. 14 ( 2022-07-15)
    Abstract: Here we report the sulfinylsulfonation of alkynes to afford β‐sulfinyl alkenylsulfone products with a broad substrate scope, excellent functional group compatibility, and high yield. Moreover, the sulfinylsulfonation reaction of enyne can also be realized for constructing functionalized carbo‐ and heterocycles through a radical cascade cyclization process.
    Type of Medium: Online Resource
    ISSN: 1861-4728 , 1861-471X
    URL: Issue
    URL: Article
    DOI: 10.1002/asia.v17.14
    DOI: 10.1002/asia.202200299
    Language: English
    Publisher: Wiley
    Publication Date: 2022
    detail.hit.zdb_id: 2233006-9
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