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  • 1
    Online Resource
    Online Resource
    Pharmacokinetics of neomycin sulfate after intravenous and oral administrations in swine
    Wiley ; 2021
    In:  Journal of Veterinary Pharmacology and Therapeutics Vol. 44, No. 5 ( 2021-09), p. 850-853
    Details
    In: Journal of Veterinary Pharmacology and Therapeutics, Wiley, Vol. 44, No. 5 ( 2021-09), p. 850-853
    Abstract: The aminoglycoside antibiotic neomycin, which is used to treat external or internal bacterial infections, is primarily administered in veterinary medicine as a sulfate salt. However, no information is available on the pharmacokinetic characteristics and absolute availability of neomycin sulfate after intravenous (i.v.) and oral (p.o.) administrations in swine. Here, these parameters were studied in swine after i.v. and p.o. doses of single 15 mg/kg body weight doses. The blood samples were assessed using ultra‐high‐performance liquid chromatography‐tandem mass/mass spectrometry (UPLC‐MS/MS) and pharmacokinetic parameters were analyzed using a non‐compartmental model. In swine, after the p.o. administration, the elimination half‐life, mean residue time from t0 to the last collection point, mean maximum concentration, mean time to reach maximum concentration and area under concentration–time curve from t0 to the last collection point values were 12.43 ± 7.63 h, 10.25 ± 4.32 h, 0.11 ± 0.07 μg/ml, 1.92 ± 0.97 h and 1.23 ± 0.78 μg·h/ml, respectively, whereas after the i.v. administration, the values were 5.87 ± 1.12 h, 6.07 ± 0.49 h, 15.80 ± 1.32 μg/ml, 0.30 ± 0.38 h and 76.14 ± 3.52 μg·h/ml, respectively. The absolute bioavailability of neomycin sulfate B was 4.84%±0.03.
    Type of Medium: Online Resource
    ISSN: 0140-7783 , 1365-2885
    URL: Issue
    URL: Article
    DOI: 10.1111/jvp.v44.5
    DOI: 10.1111/jvp.12981
    Language: English
    Publisher: Wiley
    Publication Date: 2021
    detail.hit.zdb_id: 2023924-5
    SSG: 22
    SSG: 15,3
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  • 2
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    Amorphous MoO x with High Oxophilicity Interfaced with PtMo Alloy Nanoparticles Boosts Anti‐CO Hydrogen Electrocatalysis
    Wiley ; 2023
    In:  Advanced Materials Vol. 35, No. 29 ( 2023-07)
    Details
    In: Advanced Materials, Wiley, Vol. 35, No. 29 ( 2023-07)
    Abstract: Advancing electrocatalysts for alkaline hydrogen oxidation/evolution reaction (HOR/HER) is essential for anion exchange membrane‐based devices. The state‐of‐the‐art Pt‐based electrocatalysts for alkaline HOR suffer from low intrinsic activities and severe CO poisoning due to the challenge of simultaneously optimizing surface adsorption toward different adsorbates. Herein, this challenge is overcome by tuning an atomic MoO x layer with high oxophilicity onto PtMo nanoparticles (NPs) with optimized H ad , OH ad , and CO ad adsorption for boosting anti‐CO‐poisoning hydrogen‐cycle electrocatalysis in alkaline media. For alkaline HOR, this catalyst exhibits high kinetics and an exchange current density of 3.19 mA µg Pt −1 at 50 mV versus reversible hydrogen electrode and 0.83 mA cm Pt −2 , 10.3‐ and 3.8‐fold higher than those of commercial Pt/C, respectively. For alkaline HER, it achieves an unprecedented overpotential of 37 mV at 10 mA cm −2 . Experimental and theoretical studies show that the orchestrated electronic and oxophilic regulation of the PtMo/MoO x interface NPs simultaneously optimizes H ad and OH ad adsorption for boosting alkaline hydrogen electrocatalysis, whereas reactive oxygen from the amorphous MoO x atomic layer lowers the CO oxidation reaction barrier, leading to superior anti‐poisoning ability even at 100 ppm CO.
    Type of Medium: Online Resource
    ISSN: 0935-9648 , 1521-4095
    URL: Issue
    URL: Article
    DOI: 10.1002/adma.v35.29
    DOI: 10.1002/adma.202211854
    RVK:
    UA 1538
    Language: English
    Publisher: Wiley
    Publication Date: 2023
    detail.hit.zdb_id: 1474949-X
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  • 3
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    A Universal Strategy for Intimately Coupled Carbon Nanosheets/MoM Nanocrystals (M = P, S, C, and O) Hierarchical Hollow Nanospheres for Hydrogen Evolution Catalysis and Sodium‐Ion Storage
    Wiley ; 2018
    In:  Advanced Materials Vol. 30, No. 18 ( 2018-05)
    Details
    In: Advanced Materials, Wiley, Vol. 30, No. 18 ( 2018-05)
    Abstract: Intimately coupled carbon/transition‐metal‐based hierarchical nanostructures are one of most interesting electrode materials for boosting energy conversion and storage applications owing to the strong synergistic effect between the two components and appealing structural stability. Herein, a universal method is reported for making hierarchical hollow carbon nanospheres (HCSs) with intimately coupled ultrathin carbon nanosheets and Mo‐based nanocrystals. The in situ and confined reaction of the synthetic strategy can not only allow the aggregation of the nanocrystals to be impeded, but also endows extremely intimate coupled interaction between the conductive carbon nanosheets and the nanocrystals MoM (M = P, S, C and O). As a proof of concept, the as‐prepared MoP/C HCSs exhibit extraordinary hydrogen evolution reaction electrocatalytic activity with small overpotential and robust durability in both acidic and alkaline solutions. In addition, the unique sheet‐on‐sheet MoS 2 /C HCSs as an anode demonstrate high capacity, great rate capabilities, and long‐term cycles for sodium‐ion batteries (SIBs). The capacity can be maintained at 410 mA h g −1 even after 1000 cycles even at a high current density of 4 A g −1 , one of the best reported values for MoS 2 ‐based electrode materials for SIBs. The present work highlights the importance of designing and fabricating functional strongly coupled hybrid materials for enhancing energy conversion and storage applications.
    Type of Medium: Online Resource
    ISSN: 0935-9648 , 1521-4095
    URL: Issue
    URL: Article
    DOI: 10.1002/adma.v30.18
    DOI: 10.1002/adma.201706085
    RVK:
    UA 1538
    Language: English
    Publisher: Wiley
    Publication Date: 2018
    detail.hit.zdb_id: 1474949-X
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  • 4
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    Volatile Profiles from Traditional Chinese Oat Meal Varied Significantly from Oat Porridge and Differed with Cultivars and Locations
    Wiley ; 2019
    In:  Journal of Food Science Vol. 84, No. 9 ( 2019-09), p. 2432-2440
    Details
    In: Journal of Food Science, Wiley, Vol. 84, No. 9 ( 2019-09), p. 2432-2440
    Abstract: Volatile profiles of oat‐based foods are mainly analyzed on the oat flakes and porridge as snack or breakfast, whereas the volatile characteristics of the traditional Chinese oat meal (TCOM), a popular main food in some regions of northern China, with special strong aroma, are not known. Here, we compared the volatile profiles from headspace solid phase microextraction gas chromatography–mass spectrometry analysis of oat porridge (OP) and TCOM, which were of different processing and cooking methods, from those of different cultivars, and analyzed the effect of cultivation locations on oat volatile features. Apart from the 35 volatiles shared by OP and TCOM, there were 23 and 24 volatiles specific to OP and TCOM, respectively, with the later showing more toasting and frying‐related volatiles due to the dry frying process of the grains before milling. Principle component analysis of the volatiles of OP and TCOM from 16 cultivars showed that they were clustered into two groups, and four cultivars were clustered together, independent of processing and cooking methods. The oat volatile profiles of cultivars grown in three regions of north China were dependent on the cultivation locations rather than cultivars, regardless of OP or TCOM, with those from Datong of Shanxi Province and Zhangjiakou of Hebei Province clustered together. The location effect could be due to significant less precipitation in the two regions above than the other region Ulanqab of Inner Mongolia. Practical Application The volatile compounds in oat are closely related to cultivation regions, which could be applied as a key factor by oat producers for marketing. The four cultivars showed similar and stable volatile profiles, which could be used as reference cultivars for breeding of high‐quality oat with better flavor.
    Type of Medium: Online Resource
    ISSN: 0022-1147 , 1750-3841
    URL: Issue
    URL: Article
    DOI: 10.1111/jfds.v84.9
    DOI: 10.1111/1750-3841.14682
    Language: English
    Publisher: Wiley
    Publication Date: 2019
    detail.hit.zdb_id: 2006705-7
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  • 5
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    Video‐assisted thoracic surgery lobectomy for unexpected pathologic N2 non‐small cell lung cancer
    Wiley ; 2013
    In:  Thoracic Cancer Vol. 4, No. 3 ( 2013-08), p. 287-294
    Details
    In: Thoracic Cancer, Wiley, Vol. 4, No. 3 ( 2013-08), p. 287-294
    Abstract: This study was performed to assess early and late outcomes of pathologic N2 disease unexpectedly detected in patients with non‐small cell lung cancer undergoing video‐assisted thoracic surgery ( VATS) lobectomy for clinical stage I . Methods We retrospectively reviewed the clinical features of patients with unexpected N2 non‐small cell lung cancer and their early and late outcomes in the VATS lobectomy group versus the open thoracotomy lobectomy group. Results The overall survival time for all 358 patients was 33.26 ± 0.90 months. The overall survival time for 117 cases in the VATS lobectomy group was 36.02 ± 1.44 months. The overall survival time for 241 cases in the open thoracotomy lobectomy group was 31.92 ± 1.14 months. The survival rates for patients in the VATS lobectomy group were 92.31%, 36.75%, 5.13% at one, three, and five years, respectively. The survival rates for patients in the open thoracotomy lobectomy group were 92.12%, 21.58%, 2.49% at one, three, and five years, respectively. A significant difference was found between the two groups regarding this factor ( , P = 0.049). Conclusions VATS lobectomy is feasible and safe to perform on patients with minimal N2 non‐small cell lung cancer. Even if lymph node metastasis is unexpectedly detected during surgery, with rigorous preoperative evaluation and systematic lymph node dissection, there is no need to convert to open thoracotomy lobectomy.
    Type of Medium: Online Resource
    ISSN: 1759-7706 , 1759-7714
    URL: Issue
    URL: Article
    DOI: 10.1111/tca.2013.4.issue-3
    DOI: 10.1111/1759-7714.12015
    Language: English
    Publisher: Wiley
    Publication Date: 2013
    detail.hit.zdb_id: 2559245-2
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  • 6
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    Effects of different amendments on aggregate stability and microbial communities of coastal saline–alkali soil in the Yellow River Delta
    Wiley ; 2023
    In:  Land Degradation & Development Vol. 34, No. 6 ( 2023-04-15), p. 1694-1707
    Details
    In: Land Degradation & Development, Wiley, Vol. 34, No. 6 ( 2023-04-15), p. 1694-1707
    Abstract: Organic amendments have been widely used in coastal saline–alkali soil remediation; however, the mechanisms involved and the interactions between organic and inorganic amendments are still unclear. In this work, furfural residue (particulate; C/N ratio: 51.87; O‐alkyl C + di‐O‐alkyl C: 42.35%, aromatic C: 40.89%) and black liquor (dissolved; C/N ratio: 3.11; O‐alkyl C + di‐O‐alkyl C: 32.20%, aromatic C: 28.32%) were tested to examine their effects on chemical properties, water‐stable aggregate fractions, chemical compositions of solid‐state soil organic matter (SOM), gloaming‐related soil protein contents, and microbial communities of coastal saline–alkali soil under a 400‐day incubation experiment. Furthermore, organic amendments mixed with mineral amendment (4:1) were employed to explore the interactions between organic and inorganic amendments. Furfural residue had stronger and longer effects on soil macroaggregate stability (~240 days, intense) than black liquor (~15 days, weak), and mineral amendment addition had a positive effect on the stability of microaggregates. Our results revealed that qualities (primary form, C/N ratio, and chemical composition) of organic amendment which can change microbial communities by increasing soil C/N ratio and effective chemical compositions of solid‐state SOM, are the key factors in promoting the rapid formation and longer stability of coastal saline–alkali soil aggregates. Moreover, inorganic amendment addition can further improve the formation and stability of microaggregates rather than those of macroaggregates. This study provided a much‐needed technical basis for remediation of coastal saline–alkali soil.
    Type of Medium: Online Resource
    ISSN: 1085-3278 , 1099-145X
    URL: Issue
    URL: Article
    DOI: 10.1002/ldr.v34.6
    DOI: 10.1002/ldr.4562
    Language: English
    Publisher: Wiley
    Publication Date: 2023
    detail.hit.zdb_id: 2021787-0
    detail.hit.zdb_id: 1319202-4
    SSG: 14
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  • 7
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    Green Synthesis of 5‐Hydroxymethylfurfural from Chitosan Biomass Catalyzed by Benzimidazole‐Based Ionic Liquids
    Wiley ; 2017
    In:  ChemistrySelect Vol. 2, No. 32 ( 2017-11-13), p. 10323-10328
    Details
    In: ChemistrySelect, Wiley, Vol. 2, No. 32 ( 2017-11-13), p. 10323-10328
    Abstract: 5‐Hydroxymethylfurfural (5‐HMF) is one of the most important platform chemicals in biorefinery, which could be further converted into bio‐fuels. In this work, an effective and green route for 5‐HMF production from chitosan biomass in a dimethylsulfoxide (DMSO)/water mixed solvent using acidic ionic liquids as the catalysts is reported. Several ionic liquids were successfully synthesized and used as catalysts for the degradation of chitosan. Benzimidazolium chloride ([Hbim]Cl) exhibited the best catalytic activity. We achieved a maximum 5‐HMF yield of 34.9 mol% in 10 wt% DMSO‐water mixed solvent. Moreover, the catalyst could be easily recycled and reused at least five times without a significant loss of activity. Our investigation involved the use of recycled catalysts and crustacean waste as the starting material, which makes the process “green” and sustainable.
    Type of Medium: Online Resource
    ISSN: 2365-6549 , 2365-6549
    URL: Issue
    URL: Article
    DOI: 10.1002/slct.v2.32
    DOI: 10.1002/slct.201702029
    Language: English
    Publisher: Wiley
    Publication Date: 2017
    detail.hit.zdb_id: 2844262-3
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  • 8
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    Kushen flavonoids induce apoptosis in tumor cells by inhibition of NF-κB activation and multiple receptor tyrosine kinase activities
    Wiley ; 2007
    In:  Phytotherapy Research Vol. 21, No. 3 ( 2007-03), p. 262-268
    Details
    In: Phytotherapy Research, Wiley, Vol. 21, No. 3 ( 2007-03), p. 262-268
    Type of Medium: Online Resource
    ISSN: 0951-418X , 1099-1573
    URL: Issue
    URL: Journal
    URL: Article
    DOI: 10.1002/ptr.v21:3
    DOI: 10.1002/(ISSN)1099-1573
    DOI: 10.1002/ptr.2065
    Language: English
    Publisher: Wiley
    Publication Date: 2007
    detail.hit.zdb_id: 1493490-5
    SSG: 15,3
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  • 9
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    Trimetallic Porous PtIrBi Nanoplates with Robust CO Tolerance for Enhanced Formic Acid Oxidation Catalysis
    Wiley ; 2023
    In:  Advanced Functional Materials Vol. 33, No. 31 ( 2023-08)
    Details
    In: Advanced Functional Materials, Wiley, Vol. 33, No. 31 ( 2023-08)
    Abstract: Spreading the formic acid (HCOOH) fuel cells demands a better anode electrocatalyst for the oxidation of formic acid. The catalytic efficiency of platinum (Pt)– the only choice of practicability, is mainly limited by its intrinsic affinity to CO, thus desiring a proper release. Herein, theoretical calculations are first leveraged to find that the introduction of iridium (Ir) can facilitate HCOOH oxidation with robust CO tolerance through a dehydrogenation pathway. Then, this strategy experimentally by designing a new trimetallic catalyst of 2D porous PtIrBi nanoplates (p‐PtIrBi NPs) is implemented. The optimized p‐PtIrBi NPs/C exhibits a very high mass activity of 8.2 A mg −1 pt and a high retention rate of 55.9% after the durability test, which is among the best formic acid oxidation catalysts reported to date, much higher than those of PtIrBi NPs/C, PtBi NPs/C, and Pt/C. The CO‐stripping and in situ Fourier transform infrared (FTIR) experiments collectively evidence that two types of due site, i.e., “Pt‐Bi” and “Ir‐Bi”, endow the catalyst with suppressed CO‐poisoning property to achieve super‐high activity and stability for formic acid oxidation reaction.
    Type of Medium: Online Resource
    ISSN: 1616-301X , 1616-3028
    URL: Issue
    URL: Article
    DOI: 10.1002/adfm.v33.31
    DOI: 10.1002/adfm.202303299
    Language: English
    Publisher: Wiley
    Publication Date: 2023
    detail.hit.zdb_id: 2029061-5
    detail.hit.zdb_id: 2039420-2
    SSG: 11
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  • 10
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    Development of an efficient expression system with large cargo capacity for interrogation of gene function in bamboo based on bamboo mosaic virus
    Wiley ; 2023
    In:  Journal of Integrative Plant Biology Vol. 65, No. 6 ( 2023-06), p. 1369-1382
    Details
    In: Journal of Integrative Plant Biology, Wiley, Vol. 65, No. 6 ( 2023-06), p. 1369-1382
    Abstract: Bamboo is one of the fastest growing plants among monocotyledonous species and is grown extensively in subtropical regions. Although bamboo has high economic value and produces much biomass quickly, gene functional research is hindered by the low efficiency of genetic transformation in this species. We therefore explored the potential of a bamboo mosaic virus (BaMV)‐mediated expression system to investigate genotype–phenotype associations. We determined that the sites between the triple gene block proteins (TGBps) and the coat protein (CP) of BaMV are the most efficient insertion sites for the expression of exogenous genes in both monopodial and sympodial bamboo species. Moreover, we validated this system by individually overexpressing the two endogenous genes ACE1 and DEC1 , which resulted in the promotion and suppression of internode elongation, respectively. In particular, this system was able to drive the expression of three 2A‐linked betalain biosynthesis genes (more than 4 kb in length) to produce betalain, indicating that it has high cargo capacity and may provide the prerequisite basis for the development of a DNA‐free bamboo genome editing platform in the future. Since BaMV can infect multiple bamboo species, we anticipate that the system described in this study will greatly contribute to gene function research and further promote the molecular breeding of bamboo.
    Type of Medium: Online Resource
    ISSN: 1672-9072 , 1744-7909
    URL: Issue
    URL: Article
    DOI: 10.1111/jipb.v65.6
    DOI: 10.1111/jipb.13468
    Language: English
    Publisher: Wiley
    Publication Date: 2023
    detail.hit.zdb_id: 2130095-1
    SSG: 12
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