In:
Chemistry – A European Journal, Wiley, Vol. 28, No. 49 ( 2022-09)
Abstract:
In this work we report the first cycloaddition reactions between a diazido diborane(4) and terminal alkynes, providing unique access to bis‐1,2,3‐triazoles connected by a B−B bridge. The catalyst‐free reactions are highly selective, yielding exclusively the thermodynamically disfavored bis‐1,4‐triazoles. The reactions are enabled by the high thermal stability of the diazido‐diborane [B(hpp)(N 3 )] 2 (hpp=1,3,4,6,7,8‐hexahydro‐2 H ‐pyrimido[1,2‐α]pyrimidinate). Due to the tetra‐coordinate boron atoms in this reagent, the reactions are tolerant with respect to the introduction of Lewis‐basic groups at the alkyne. The scope and limitations of the new reactions are discussed.
Type of Medium:
Online Resource
ISSN:
0947-6539
,
1521-3765
DOI:
10.1002/chem.202201389
Language:
English
Publisher:
Wiley
Publication Date:
2022
detail.hit.zdb_id:
1478547-X
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