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  • 1
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    Online Resource
    A New Approach for Evaluating Palatine Tonsillar Hypertrophy in Children Based on Ultrasound: A Pilot Study
    Wiley ; 2022
    In:  Journal of Ultrasound in Medicine Vol. 41, No. 12 ( 2022-12), p. 3023-3029
    Details
    In: Journal of Ultrasound in Medicine, Wiley, Vol. 41, No. 12 ( 2022-12), p. 3023-3029
    Abstract: To develop a novel ultrasound (US) plane to diagnose palatine tonsillar hypertrophy objectively in children. Methods Tonsillar ultrasonography of children (age 2–14 years) who had a clinical diagnosis of tonsillar hypertrophy or not were analyzed retrospectively. Clinical data (including gender, age, body mass index (BMI)), and volume ( V ) of tonsils measured by the US, were recorded. Furthermore, we found a new US plane to diagnose tonsillar hypertrophy and named it the submental oblique cross‐section. In this plane, diameters of the left tonsil, right tonsil, and central oropharynx were designated as T 1, T 2, and O . Then, we calculated the ratio by the formula ( T 1 +  T 2)/ O . Results A total of 172 cases (85 hypertrophy and 87 non‐hypertrophy) were included in this study. There were no significant differences in gender ( P  = .844), age ( P  = .666), and BMI ( P  = .089) between the groups. In the non‐hypertrophy group, the V of both sides had a positive linear correlation with age or BMI. In contrast, there was no linear correlation between ratio and age or BMI. The area under the curve (AUC) of ratio and V was 0.970 (95%CI: 0.947–0.993) and 0.835 (95%CI: 0.778–0.893) by receiver operating characteristic (ROC) analysis, respectively. The optimal cutoff value of ratio for diagnosis of tonsillar hypertrophy was 2.293 (sensitivity = 88.2%, specificity = 95.4%). Conclusions We established a new US section to evaluate tonsillar hypertrophy. This approach could be easily acquired and provide a reference value to guide clinical practice.
    Type of Medium: Online Resource
    ISSN: 0278-4297 , 1550-9613
    URL: Issue
    URL: Article
    DOI: 10.1002/jum.v41.12
    DOI: 10.1002/jum.16030
    Language: English
    Publisher: Wiley
    Publication Date: 2022
    detail.hit.zdb_id: 2067124-6
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  • 2
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    Curved microstructures promote osteogenesis of mesenchymal stem cells via the RhoA/ ROCK pathway
    Wiley ; 2017
    In:  Cell Proliferation Vol. 50, No. 4 ( 2017-08)
    Details
    In: Cell Proliferation, Wiley, Vol. 50, No. 4 ( 2017-08)
    Abstract: Cells in the osteon reside in a curved space, accordingly, the curvature of the microenvironment is an important geometric feature in bone formation. However, it is not clear how curved microstructures affect cellular behaviour in bone tissue. Materials and methods Rat primary bone marrow mesenchymal stem cells ( BMSC s) on wavy microgrooves were exposed to PDMS substrates with various curvatures to investigate alterations in cellular morphology and osteogenic differentiation. Additionally, the expression levels of RhoA and its effectors were examined by immunofluorescence and quantitative PCR to determine the mechanisms of curvature‐dependent osteogenic differentiation. Results Wavy microgrooves caused dramatic nuclear distortion and cytoskeletal remodelling. We detected a noticeable increase in the expression of osteogenic‐related genes in BMSC s in wavy microgroove groups, and the maximum expression was observed in the high curvature group. Moreover, immunofluorescent staining and quantitative RT ‐ PCR results for RhoA and its effectors showed that the RhoA/ ROCK signalling pathway is associated with curvature‐dependent osteogenic differentiation. Conclusions Our results illustrated that curved microstructures could promote BMSC differentiation to the osteogenic lineage, and the osteogenic effects of higher curvature are more obvious. Wavy microstructures could also influence the RhoA/ ROCK pathway. Accordingly, curved microstructures may be useful in bone tissue engineering.
    Type of Medium: Online Resource
    ISSN: 0960-7722 , 1365-2184
    URL: Issue
    URL: Article
    DOI: 10.1111/cpr.2017.50.issue-4
    DOI: 10.1111/cpr.12356
    Language: English
    Publisher: Wiley
    Publication Date: 2017
    detail.hit.zdb_id: 2019986-7
    SSG: 12
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  • 3
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    Recent Advances in Catalyst Structure and Composition Engineering Strategies for Regulating CO 2 Electrochemical Reduction
    Wiley ; 2021
    In:  Advanced Materials Vol. 33, No. 50 ( 2021-12)
    Details
    In: Advanced Materials, Wiley, Vol. 33, No. 50 ( 2021-12)
    Abstract: Electrochemical CO 2 reduction has been recognized as a promising solution in tackling energy‐ and environment‐related challenges of human society. In the past few years, the rapid development of advanced electrocatalysts has significantly improved the efficiency of this reaction and accelerated the practical applications of this technology. Herein, representative catalyst structures and composition engineering strategies in regulating the CO 2 reduction selectivity and activity toward various products including carbon monoxide, formate, methane, methanol, ethylene, and ethanol are summarized. An overview of in situ/operando characterizations and advanced computational modeling in deepening the understanding of the reaction mechanisms and accelerating catalyst design are also provided. To conclude, future challenges and opportunities in this research field are discussed.
    Type of Medium: Online Resource
    ISSN: 0935-9648 , 1521-4095
    URL: Issue
    URL: Article
    DOI: 10.1002/adma.v33.50
    DOI: 10.1002/adma.202005484
    RVK:
    UA 1538
    Language: English
    Publisher: Wiley
    Publication Date: 2021
    detail.hit.zdb_id: 1474949-X
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  • 4
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    Effects of Different Enzymatic Hydrolyses of Mutton Tallow on the Aroma Characteristics of the Maillard Reaction of Xylose–Cysteine Based on GC‐MS, E‐Nose, and Statistical Analysis
    Wiley ; 2020
    In:  European Journal of Lipid Science and Technology Vol. 122, No. 3 ( 2020-03)
    Details
    In: European Journal of Lipid Science and Technology, Wiley, Vol. 122, No. 3 ( 2020-03)
    Abstract: Solid‐phase micro extraction/gas chromatography‐mass spectrometry (SPME/GC‐MS), electronic nose (E‐nose), and descriptive sensory analysis (DSA) are used to evaluate the changes in aroma characteristic of six mutton tallow flavor (MF) samples prepared from xylose–cysteine with mutton tallow or different enzymatic hydrolysis mutton tallow (EM) with different enzymes. 61 compounds are identified by GC‐MS as crucial compounds contributing to the MF for the evaluation of the sensory characteristics of MFs. Most of the volatiles, including aldehydes, alcohols, furans, and thiophenes, decrease because of the addition of EMs. The EM with lipase MER produces more appropriate volatile compounds through the Maillard reaction than the other samples. Five attributes are selected for the appraisal of MFs. DSA results show a remarkable difference in sensory attributes among the MFs. MF5 has the strongest aroma in the muttony and meaty flavors, and the weakest in the burnt and off‐flavor. Further investigation of the six MFs is conducted based on the volatile compounds evaluated by E‐nose. The results of the correlation analysis among the volatile compounds and the DSA confirm that EM with lipase MER may be an appropriate precursor for MF's sensory characteristics. Practical Applications : Moderate lipid oxidation is a prerequisite to achieving a characteristic flavor. However, over‐treatment will lead to an undesirable smell. The thermal method requires high temperature and is difficult to control, and the resulting natural meat flavor needs improvement. A possible solution is to use enzymes to make a difference in the molecular weight of the enzymatically hydrolyzed fragments. To achieve controlled enzymatic hydrolysis of a fragment, the correct selection of enzyme is an important step. The present study helps elucidate how lipids contribute to the formation of meat flavor, thereby providing guidance for the preparation of thermal reaction meat flavor.
    Type of Medium: Online Resource
    ISSN: 1438-7697 , 1438-9312
    URL: Issue
    URL: Article
    DOI: 10.1002/ejlt.v122.3
    DOI: 10.1002/ejlt.201900212
    Language: English
    Publisher: Wiley
    Publication Date: 2020
    detail.hit.zdb_id: 2012720-0
    SSG: 21
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  • 5
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    Evaluation of classification ability of logistic regression model on SERS data of miRNAs
    Wiley ; 2022
    In:  Journal of Biophotonics Vol. 15, No. 12 ( 2022-12)
    Details
    In: Journal of Biophotonics, Wiley, Vol. 15, No. 12 ( 2022-12)
    Abstract: Logistic regression (LR) is a supervised multiple linear regression model, which uses linear weighted calculation for input to obtain weight coefficients of model. The surface enhanced Raman spectroscopy (SERS) technology greatly enhances the Raman signal of analyte. LR model was used to analyze the data of seven types of pancreatic cancer‐related miRNAs obtained from commercial SERS substrate. The classification ability of the model on such data was observed under the configurations of different key parameters (classification mode, regularization method and loss function optimization way), and the effect of the two types of data formats were also evaluated. The results showed that though LR model used to classify this data did not perform well as expected, miRNA‐191 and miRNA‐4306 still had high recalls (sensitivity), which laid a theoretical foundation for the purpose of using LR model to identify these two miRNAs to jointly diagnose of pancreatic cancer at miRNA level.
    Type of Medium: Online Resource
    ISSN: 1864-063X , 1864-0648
    URL: Issue
    URL: Article
    DOI: 10.1002/jbio.v15.12
    DOI: 10.1002/jbio.202200108
    Language: English
    Publisher: Wiley
    Publication Date: 2022
    detail.hit.zdb_id: 2403788-6
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  • 6
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    An Intermediate Unit‐Mediated, Continuous Structural Inheritance Strategy for the Dilemma between Injectability and Robustness of Hydrogels
    Wiley ; 2022
    In:  Advanced Functional Materials Vol. 32, No. 14 ( 2022-04)
    Details
    In: Advanced Functional Materials, Wiley, Vol. 32, No. 14 ( 2022-04)
    Abstract: Hydrogels with injectability and robustness have great promise in clinical practice. However, current injectable hydrogels are usually mechanically weak. Here, an idea, “preformed hydrogel reversion”, is proposed to develop robust injectable hydrogels through an intermediate unit‐mediated, continuous structural inheritance strategy. In this strategy, robust preformed hydrogels are physically disassembled into intermediate injectable structure‐inherited microgels (SIMs), and upon encountering water in physiological environment, the SIMs can construct a macroscopical robust structure with the driving force of hydrogen bonds (H‐bonds). The physical disassembly and construction process enables the inheritance of robust structures through SIMs, thereby realizing both excellent injectability and robustness. Beyond that, the SIMs also exhibit long‐term storage stability and convenient usability. Using protein drug loading and hemostasis as examples, it is demonstrated that the SIM system shows superiorities in biomedical applications. The proposed idea of “preformed hydrogel reversion” can open new horizons for developing robust injectable hydrogels for diverse applications.
    Type of Medium: Online Resource
    ISSN: 1616-301X , 1616-3028
    URL: Issue
    URL: Article
    DOI: 10.1002/adfm.v32.14
    DOI: 10.1002/adfm.202110617
    Language: English
    Publisher: Wiley
    Publication Date: 2022
    detail.hit.zdb_id: 2029061-5
    detail.hit.zdb_id: 2039420-2
    SSG: 11
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  • 7
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    High‐Entropy Spinel Oxide Nanofibers as Catalytic Sulfur Hosts Promise the High Gravimetric and Volumetric Capacities for Lithium–Sulfur Batteries
    Wiley ; 2022
    In:  ENERGY & ENVIRONMENTAL MATERIALS Vol. 5, No. 2 ( 2022-04), p. 645-654
    Details
    In: ENERGY & ENVIRONMENTAL MATERIALS, Wiley, Vol. 5, No. 2 ( 2022-04), p. 645-654
    Abstract: The exploration of new catalytic hosts is highly important to tackle the sluggish electrochemical kinetics of sulfur redox for achieving high energy density of lithium–sulfur batteries. Herein, for the first time, we present high‐entropy oxide (HEO, (Mg 0.2 Mn 0.2 Ni 0.2 Co 0.2 Zn 0.2 )Fe 2 O 4 ) nanofibers as catalytic host of sulfur. The HEO nanofibers show a synergistic effect among multiple metal cations in spinel structure that enables strong chemical confinement of soluble polysulfides and fast kinetics for polysulfide conversion. Consequently, the S/HEO composite displays the high gravimetric capacity of 1368.7 mAh g −1 at 0.1 C rate, excellent rate capability with the discharge capacity of 632.1 mAh g −1 at 5 C rate, and desirable cycle stability. Furthermore, the S/HEO composite shows desirable sulfur utilization and good cycle stability under a harsh operating condition of high sulfur loading (4.6 mg cm −2 ) or low electrolyte/sulfur ratio (5 μL mg −1 ). More impressively, the high volumetric capacity of 2627.9 mAh cm −3 is achieved simultaneously for the S/HEO composite due to the high tap density of 1.92 g cm −3 , nearly 2.5 times of the conventional sulfur/carbon composite. Therefore, based on high‐entropy oxide materials, this work affords a fresh concept of elevating the gravimetric/volumetric capacities of sulfur cathodes for lithium–sulfur batteries.
    Type of Medium: Online Resource
    ISSN: 2575-0356 , 2575-0356
    URL: Issue
    URL: Article
    DOI: 10.1002/eem2.v5.2
    DOI: 10.1002/eem2.12215
    Language: English
    Publisher: Wiley
    Publication Date: 2022
    detail.hit.zdb_id: 2945579-0
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  • 8
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    Online Resource
    Flavor quality evaluation system of Xinjiang milk knots by using SOM neural network and the fuzzy AHP
    Wiley ; 2020
    In:  Food Science & Nutrition Vol. 8, No. 4 ( 2020-04), p. 2088-2093
    Details
    In: Food Science & Nutrition, Wiley, Vol. 8, No. 4 ( 2020-04), p. 2088-2093
    Abstract: Self‐made milk knots in Xinjiang Kazakh ethnic group were used as material to establish the quality assessment system of flavor quality. The fuzzy analytic hierarchy process based on the optimal consistency matrix was used to evaluate the quality of the samples qualitatively and quantitatively. Its result is consistent with the cluster analysis of the SOM neural network. The results showed that the milk knot samples of Altay had differences with the milk knot samples of Yili. The comprehensive evaluation system is feasible and can evaluate the quality of milk knot samples by flavor characteristics. This can provide a reference for further research on the origin of differences between two types of milk knot samples.
    Type of Medium: Online Resource
    ISSN: 2048-7177 , 2048-7177
    URL: Issue
    URL: Article
    DOI: 10.1002/fsn3.v8.4
    DOI: 10.1002/fsn3.1501
    Language: English
    Publisher: Wiley
    Publication Date: 2020
    detail.hit.zdb_id: 2703010-6
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  • 9
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    Study on damping and self‐healing properties of polyurethane materials based on dynamic synergetic control of disulfide bond and imine bond
    Wiley ; 2023
    In:  Journal of Applied Polymer Science Vol. 140, No. 42 ( 2023-11-10)
    Details
    In: Journal of Applied Polymer Science, Wiley, Vol. 140, No. 42 ( 2023-11-10)
    Abstract: Polyurethane is a widely used viscoelastic polymer known for its exceptional damping properties. This paper focuses on the introduction of disulfide and imine bonds into the polyurethane matrix to enhance its damping capabilities, mechanical properties, and self‐healing ability. Dynamic mechanical analysis shows that the synergistic effect of disulfide bond and imine bonds extends the effective damping temperature range of the polyurethane to 118°C (−18 to 100°C), while the effective damping frequency extrapolates to a range of 10 −2 –10 5  Hz. Furthermore, the addition of imide bonds compensates for the relatively low mechanical properties associated with disulfide bonds, allowing the polyurethane to achieve a tensile strength of 14.7 MPa at room temperature. Self‐repair tests reveal that the combined action of these two dynamic bonds enables a remarkable 97% repair efficiency of polyurethane, exhibiting excellent self‐healing performance. This study presents a novel approach to enhance the comprehensive properties of polyurethane.
    Type of Medium: Online Resource
    ISSN: 0021-8995 , 1097-4628
    URL: Issue
    URL: Article
    DOI: 10.1002/app.v140.42
    DOI: 10.1002/app.54544
    Language: English
    Publisher: Wiley
    Publication Date: 2023
    detail.hit.zdb_id: 1491105-X
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  • 10
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    Effects of influent loads on performance and microbial community dynamics of aerobic granular sludge treating piggery wastewater
    Wiley ; 2018
    In:  Journal of Chemical Technology & Biotechnology Vol. 93, No. 5 ( 2018-05), p. 1443-1452
    Details
    In: Journal of Chemical Technology & Biotechnology, Wiley, Vol. 93, No. 5 ( 2018-05), p. 1443-1452
    Abstract: Understanding how influent loads affect the microbial community may promote applications of aerobic granular sludge (AGS). Herein, performance and microbial community dynamics of the AGS were assessed with stepwise increasing influent loads. RESULTS AGS exhibited good structure stability and effective removal efficiency; when the influent load increased from 6.5 kg COD m ‐3 d ‐1 (0.255 NH 4 + ‐N m ‐3 d ‐1 ) to 10.1 kg COD m ‐3 d ‐1 (0.455 kg NH 4 + ‐N m ‐3 d ‐1 ). COD and NH 4 + ‐N removal efficiencies reached 97.1–97.9% and 84.5–98%, respectively. As indicated from the PCR‐DGGE results, the microbial community and dominant species in the AGS also gradually evolved along with the increase of influent loads. A coincidence was observed, namely, three main distinct clusters of the phylogenetic tree appeared respectively in the three stages of influent loads. The microbial diversity attained a maximum in the medium loads stage. The identified bacteria mainly belonged to Proteobacteria, Actinobacteria, Bacteroidetes and Firmicutes. The dominant species were responsible for the AGS stability and pollutant removal. CONCLUSION Variation in the influent load strongly affected the microbial community dynamics, and hence the AGS performance. These results and understanding could lead to potential improvements in guiding AGS wastewater treatment. © 2017 Society of Chemical Industry
    Type of Medium: Online Resource
    ISSN: 0268-2575 , 1097-4660
    URL: Issue
    URL: Article
    DOI: 10.1002/jctb.2018.93.issue-5
    DOI: 10.1002/jctb.5512
    Language: English
    Publisher: Wiley
    Publication Date: 2018
    detail.hit.zdb_id: 1479465-2
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