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  • Wiley  (11)
  • 1
    Online Resource
    Online Resource
    Wiley ; 2021
    In:  Advanced Engineering Materials Vol. 23, No. 6 ( 2021-06)
    In: Advanced Engineering Materials, Wiley, Vol. 23, No. 6 ( 2021-06)
    Abstract: Integrated flexible nonenzymatic electrochemical glucose sensors have attracted substantial interest because they enable portable noninvasive glucose detection stably and accurately. Manufacturing of these sensors generally requires complex step‐by‐step processes, including synthesis of noble and functional materials, patterning the as‐synthesized noble materials into electrodes/contacts, and subsequent working electrode functionalizing. Herein, the one‐step fabrication of a working electrode and electrical contacts on a flexible substrate for an integrated sensor is realized through laser writing of a low‐cost Cu ionic precursor. The obtained Cu 2 O/Cu porous structure not only has a low sheet resistance of 1.3 Ω sq −1 to ensure signal transmission in the sensor, but also provides a remarkable sensing performance for glucose detection, especially at a low detection potential of 0.3 V and a low detection limit of 0.34 μ m . Due to its anti‐interference and flexibility, the integrated sensor has the potential to directly detect trace amounts of glucose in body fluids as demonstrated in sweat sensing. This work highlights an efficient route to fabricate low‐cost integrated flexible electrochemical sensors.
    Type of Medium: Online Resource
    ISSN: 1438-1656 , 1527-2648
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2021
    detail.hit.zdb_id: 2016980-2
    detail.hit.zdb_id: 1496512-4
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  • 2
    Online Resource
    Online Resource
    Wiley ; 2020
    In:  Advanced Materials Interfaces Vol. 7, No. 4 ( 2020-02)
    In: Advanced Materials Interfaces, Wiley, Vol. 7, No. 4 ( 2020-02)
    Abstract: Proximity and tactile sensors are important in human–machine interaction, which are usually fabricated with complex processes. In this study, a facile assembling method to fabricate these sensors on flexible substrate is presented. Using one‐step laser‐patterned highly conductive Cu electrodes on polyimide sheets and polydimethylsiloxane dielectric layer, single‐pixel proximity sensor with long detecting range and multichannel tactile sensor with high planar sensitivity are fabricated. Both sensors exhibit long term stability and repeatability throughout hundreds of testing cycles. This study highlights a rapid and low cost assembling for fabricating of capacitive sensors.
    Type of Medium: Online Resource
    ISSN: 2196-7350 , 2196-7350
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2020
    detail.hit.zdb_id: 2750376-8
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  • 3
    In: Ecology and Evolution, Wiley, Vol. 7, No. 21 ( 2017-11), p. 8804-8811
    Abstract: Excessive sugar consumption could lead to high blood glucose levels that are harmful to mammalian health and life. Despite consuming large amounts of sugar‐rich food, fruit bats have a longer lifespan, raising the question of how these bats overcome potential hyperglycemia. We investigated the change of blood glucose level in nectar‐feeding bats ( Eonycteris spelaea ) and fruit‐eating bats ( Cynopterus sphinx ) via adjusting their sugar intake and time of flight. We found that the maximum blood glucose level of C. sphinx was higher than 24 mmol/L that is considered to be pathological in other mammals. After C. sphinx bats spent approximately 75% of their time to fly, their blood glucose levels dropped markedly, and the blood glucose of E. spelaea fell to the fast levels after they spent 70% time of fly. Thus, the level of blood glucose elevated with the quantity of sugar intake but declined with the time of flight. Our results indicate that high‐intensive flight is a key regulator for blood glucose homeostasis during foraging. High‐intensive flight may confer benefits to the fruit bats in foraging success and behavioral interactions and increases the efficiency of pollen and seed disposal mediated by bats.
    Type of Medium: Online Resource
    ISSN: 2045-7758 , 2045-7758
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2017
    detail.hit.zdb_id: 2635675-2
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  • 4
    Online Resource
    Online Resource
    Wiley ; 2021
    In:  Advanced Engineering Materials Vol. 23, No. 12 ( 2021-12)
    In: Advanced Engineering Materials, Wiley, Vol. 23, No. 12 ( 2021-12)
    Abstract: The growing demand for highly efficient heat management in flexible electronics requires fabrication of highly conductive flexible films. Herein, Cu–C film on a polyimide (PI) substrate is fabricated to form a layered Cu–C/PI composite conductive film using direct laser writing. Its oxidation resistance is significantly improved compared with the written Cu film due to the presence of a graphite shell on Cu particles in the Cu–C film. Furthermore, the Cu–C/PI composite film shows better thermal properties than Cu/PI. This work provides a one‐step method for rapidly fabricating Cu/PI and Cu–C/PI composites with good thermal stability and conductivity.
    Type of Medium: Online Resource
    ISSN: 1438-1656 , 1527-2648
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2021
    detail.hit.zdb_id: 2016980-2
    detail.hit.zdb_id: 1496512-4
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  • 5
    Online Resource
    Online Resource
    Wiley ; 2020
    In:  Oral Diseases Vol. 26, No. 7 ( 2020-10)
    In: Oral Diseases, Wiley, Vol. 26, No. 7 ( 2020-10)
    Type of Medium: Online Resource
    ISSN: 1354-523X , 1601-0825
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2020
    detail.hit.zdb_id: 2008428-6
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  • 6
    Online Resource
    Online Resource
    Wiley ; 2020
    In:  Oral Diseases Vol. 26, No. 7 ( 2020-10), p. 1502-1512
    In: Oral Diseases, Wiley, Vol. 26, No. 7 ( 2020-10), p. 1502-1512
    Abstract: The study aimed to explore the effects of mouth breathing and hypoxia on the condyle of temporomandibular joint (TMJ) via two animal models. Methods 24 four‐week‐old rats were randomly separated into three groups, consisting of eight control rats, eight intermittent hypoxia (IH) rats, and eight intermittent nasal obstruction (INO) rats. We use the IH model and the INO model to simulate children suffering from hypoxia and mouth breathing. After 16 days, the condyle of TMJ and surrounding white adipose tissue (WAT) and skeletal muscle tissue were obtained for further staining and qRT‐PCR. Finally, RNA‐seq was used to verify the results. Results The intermittent hypoxia cannot significantly change the overall structure in the cause of short‐term hypoxia stimulation, but the intermittent nasal obstruction can alter the condyle, WAT, and muscle, while also introducing noticeable structural changes in tissue hypoxia and macrophage infiltration. Sequencing data verified these findings and also suggested that this process might involve the Hif‐1α/Vegf axis. Conclusions Our findings reveal the very early structural impact of mouth breathing on condyle reconstruction in rat models, and hypoxia does not induce evident alteration on condyle. However, since these results are mainly focused on rats, further studies are needed to understand its effects on humans.
    Type of Medium: Online Resource
    ISSN: 1354-523X , 1601-0825
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2020
    detail.hit.zdb_id: 2008428-6
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  • 7
    Online Resource
    Online Resource
    Wiley ; 2020
    In:  Journal of Cellular Physiology Vol. 235, No. 4 ( 2020-04), p. 3634-3645
    In: Journal of Cellular Physiology, Wiley, Vol. 235, No. 4 ( 2020-04), p. 3634-3645
    Abstract: Exosomes derived from differentiated P12 cells and MSCs were proved to suppress apoptosis of neuron cells, and phosphatase and tensin homolog pseudogene 1 (PTENP1) was reported to inhibit cell proliferation. In this study, we aimed to investigate the role of PTENP1 in the process of post‐spinal cord injury (SCI) recovery, so as to evaluate the therapeutic effects of exosomes derived from MSCs transfected with PTENP1 short hairpin RNA (shRNA), as a type of novel biomarkers in the treatment of SCI. Electron microscopy was used to observe the morphology of different exosomes. Real‐time polymerase chain reaction and western blot, 3‐(4,5‐dimethylthiazol‐2‐yl)‐2,5‐diphenyltetrazolium bromide assays, flow cytometry, Nissl staining, immunohistochemistry assay, and terminal deoxynucleotidyl transferase dUTP nick end labeling assay were conducted to investigate and validate the underlying molecular signaling pathway. PTENP1‐shRNA downregulated PTENP1 and PTEN while upregulating miR‐21 and miR‐19b. PTENP1‐shRNA also accelerated cell apoptosis and reduced cell viability. In addition, PTENP1 reduced the miR‐21 and miR‐19b expression by directly targeting miR‐21 and miR‐19b. Meanwhile, both miR‐21 and miR‐19b reduced the expression of PTEN by directly targeting the 3′‐untranslated region of PTEN. Furthermore, PTEN level and apoptosis index of neuron cells was the highest in the SCI group, while the treatment with exosomes+PTENP1‐shRNA reduced the PTEN expression to a level similar to that in the sham group. Finally, PTENP1 inhibited miR‐21 and miR‐19b expression but upregulated PTEN expression. The upregulation of miR‐21/miR‐19b also suppressed the apoptosis of neuron cells by downregulating the PTEN expression. PTENP1 is involved in the recovery of SCI by regulating the expression of miR‐19b and miR‐21, and exosomes from PTENP1‐shRNA‐transfected cells may be used as a novel biomarker in SCI treatment.
    Type of Medium: Online Resource
    ISSN: 0021-9541 , 1097-4652
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2020
    detail.hit.zdb_id: 1478143-8
    SSG: 12
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  • 8
    Online Resource
    Online Resource
    Wiley ; 2019
    In:  Ecology and Evolution Vol. 9, No. 14 ( 2019-07), p. 8113-8118
    In: Ecology and Evolution, Wiley, Vol. 9, No. 14 ( 2019-07), p. 8113-8118
    Abstract: Grooming is a common behavior of some mammals. Previous studies have shown that grooming is a means by which animals clean themselves, remove ectoparasites, and lower their body temperature. It is also involved in olfactory communication. Bats belong to the order Chiroptera and, like most mammals, are the natural host of many ectoparasites. Bat grooming, including licking and scratching, is one of the ways to reduce the adverse effects caused by ectoparasites. Bat grooming may also be induced by exogenous odor. In this study, we used lesser flat‐headed bats ( Tylonycteris pachypus ) to test the hypothesis that exogenous odor affects the self‐grooming behavior of bats. Results showed that external odor from distantly related species caused lesser flat‐headed bats to spend more time in self‐grooming. Lesser flat‐headed bats that received odor from humans spent the longest time in self‐grooming, followed by those that received odor from a different species of bats ( T. robustula ). Lesser flat‐headed bats that received odor form the same species of bats, either from the same or a different colony, spent the least amount of time in self‐grooming. These results suggest that bats can recognize conspecific and heterospecific through body scent.
    Type of Medium: Online Resource
    ISSN: 2045-7758 , 2045-7758
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2019
    detail.hit.zdb_id: 2635675-2
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  • 9
    In: Advanced Healthcare Materials, Wiley, Vol. 11, No. 18 ( 2022-09)
    Abstract: Optically monitoring hypochlorous acid (HClO) in living body favors diagnosis and study of inflammatory diseases. However, this has been hampered by limited strategies to develop highly fluorogenic tools in the deep‐penetration near‐infrared spectrum. Herein, a near‐infrared aza‐BODIPY‐bisferrocene triad Fc 2 ‐CBDP that unexpectedly achieves an exceptionally sensitive and selective fluorescence turn‐on ( 〉 220‐fold) response toward HClO through single‐ferrocene oxidation and boron‐alkynyl hydrolysis cascade is reported. Mechanism insight shows that Fc 2 ‐CBDP features “enhanced charge transfer”‐caused quenching due to intramolecular bisferrocene electronic coupling, which is decoupled in the reaction with HClO. The utility of Fc 2 ‐CBDP for intracellular HClO imaging is evaluated and, more importantly, in vivo high‐contrast deep‐tissue imaging of lymphatic inflammation and colitis is realized. This work provides new insights into both HClO and ferrocene chemistry, and extends the reach of fluorogenic strategies in the near‐infrared biosensing.
    Type of Medium: Online Resource
    ISSN: 2192-2640 , 2192-2659
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2022
    detail.hit.zdb_id: 2645585-7
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  • 10
    In: AIChE Journal, Wiley, Vol. 69, No. 2 ( 2023-02)
    Abstract: Herein, thin‐film composite membranes consisting of poly(m‐phenyleneisophthalamide) substrate and polyamide active layer were constructed by transition metal ion‐assisted interfacial polymerization method. As compared to the traditional polyamide membranes, a much thinner polyamide layer (33 vs. 200 nm) can be synthesized with higher permeance (3.2 vs. 0.62 L m −2  h −1  bar −1 ) in the organic solvent nanofiltration. Similarly, the prepared membranes maintained a high rejection ( 〉 99%) for various dyes. Optimal membranes prepared by using Co 2+ exhibited strong tolerance to various organic solvents with good long‐term stability. Positron annihilation spectroscopy and other characterization methods were used to investigate the relationships between the membrane microstructures and the enhanced separation performance. Based on molecular dynamics simulation, it was found that the diffusion coefficient of polyethyleneimine monomer decreased by about 18 times after adding Co 2+ to the aqueous solution (forming coordination interaction). This procedure has great potential and sustainability for practical organic solvent nanofiltration applications.
    Type of Medium: Online Resource
    ISSN: 0001-1541 , 1547-5905
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2023
    detail.hit.zdb_id: 2020333-0
    detail.hit.zdb_id: 240008-X
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