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  • 1
    Online Resource
    Online Resource
    Charge‐Transfer and Arrangement Effects on Delayed Photoluminescence from Phthalimide Cocrystals
    Wiley ; 2018
    In:  ChemPhotoChem Vol. 2, No. 1 ( 2018-01), p. 42-52
    Details
    In: ChemPhotoChem, Wiley, Vol. 2, No. 1 ( 2018-01), p. 42-52
    Abstract: Cocrystals of N ‐4‐trifluoromethylphenylphthalimides 1 a⊇2 a(1 %) , composed of bromo ( 1 a ) and dimethylamino ( 2 a ) derivatives in a 99:1 ratio, display delayed photoluminescence (DPL) at λ em =535 nm with a lifetime of 0.26 s. In contrast, pure materials 1 a and 2 a do not exhibit DPL. Similar DPL emission is also observed for cocrystals 1⊇2(1 %) of N ‐4‐pyridyl, N ‐phenyl, and N ‐4‐tolyl derivatives. X‐Ray crystallographic analyses and the results of density functional theory calculations revealed that key for the occurrence of DPL is the formation of charge‐transfer (CT) excited states 1 ( 2 a ⋅ 1 a ) CT * and the existence of regularly aligned networks in the cocrystals, which leads to generation of the long‐lived excited state 3 1 a via 3 ( 2 a ⋅ 1 a ) CT * by intersystem crossing and localization of triplet energy.
    Type of Medium: Online Resource
    ISSN: 2367-0932 , 2367-0932
    URL: Issue
    URL: Article
    DOI: 10.1002/cptc.v2.1
    DOI: 10.1002/cptc.201700112
    Language: English
    Publisher: Wiley
    Publication Date: 2018
    detail.hit.zdb_id: 2881321-2
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  • 2
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    Online Resource
    Pancreas‐preserving resection of lower biliary tract adenocarcinoma: A coring‐out technique
    Wiley ; 2017
    In:  Annals of Gastroenterological Surgery Vol. 1, No. 2 ( 2017-06), p. 150-155
    Details
    In: Annals of Gastroenterological Surgery, Wiley, Vol. 1, No. 2 ( 2017-06), p. 150-155
    Abstract: Surgical resection for distal cholangiocarcinoma is usually carried out using pancreaticoduodenectomy ( PD ). However, because PD is a complex procedure with a high rate of postoperative complications, the surgical indications should be carefully considered, especially for patients with a decreased performance status, significant comorbidities, and/or anatomical anomalies. If curatively carried out, a less invasive, local resection may be an alternative procedure for such patients. In the current study, we present pancreas‐preserving resection of the lower biliary tract in a patient with early‐stage distal cholangiocarcinoma. This procedure was selected to avoid PD with arterial reconstruction because of arterial anomalies. After an abdominal exploration, a cholecystectomy was carried out and the common hepatic duct was transected. The bile duct was dissected from the pancreatic parenchyma without pancreatic resection, downward to the biliopancreatic ductal confluence. Next, a duodenotomy was done opposite Vater's ampulla. The duodenal mucosa around Vater's ampulla was incised and dissected, and the main pancreatic duct ( MPD ) was divided. The bile duct was completely separated from the pancreatic parenchyma, and the lower biliary tract was totally “cored‐out”. After resection, the MPD was re‐implanted into the duodenal wall, and the duodenotomy was closed. Finally, a Roux‐en‐Y hepaticojejunostomy was created. Postoperative course was uneventful. No tumor recurrence has been observed for 21 months after the operation. Thus, pancreas‐preserving resection of the lower biliary tract appeared to be appropriate for our patient. This organ‐preserving approach can be a useful, alternative procedure in selected patients.
    Type of Medium: Online Resource
    ISSN: 2475-0328 , 2475-0328
    URL: Issue
    URL: Article
    DOI: 10.1002/ags3.2017.1.issue-2
    DOI: 10.1002/ags3.12021
    Language: English
    Publisher: Wiley
    Publication Date: 2017
    detail.hit.zdb_id: 2895706-4
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  • 3
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    Online Resource
    Gram staining of gallbladder bile samples is useful for predicting surgical site infection in acute cholecystitis patients undergoing an early cholecystectomy
    Wiley ; 2020
    In:  Journal of Hepato-Biliary-Pancreatic Sciences Vol. 27, No. 12 ( 2020-12), p. 962-967
    Details
    In: Journal of Hepato-Biliary-Pancreatic Sciences, Wiley, Vol. 27, No. 12 ( 2020-12), p. 962-967
    Abstract: Microbiological assessment of gallbladder bile is important for postoperative management in cholecystectomy for acute cholecystitis (AC). Gram staining is used as the first step in the assessment, in order to preliminarily detect bacteria in the bile sample. This study was conducted to evaluate the clinical significance of Gram staining results in the development of postoperative surgical site infection (SSI) in AC patients. Methods A total of 428 AC patients, who underwent an early cholecystectomy with microbiological assessment of gallbladder bile, were enrolled in this retrospective study. The clinical usefulness of the Gram staining results was evaluated by univariate and multivariate regression analyses. Results Of the 428 patients, 298 patients (69.6%) were diagnosed with bile infection by the Gram staining method. The rate of SSI was higher in patients with bile infection (9.7%) than in those without the infection (0.8%). The multivariate analysis indicated that the bile infection diagnosed by Gram staining (odds ratio: 9.091; P  = .033) was an independent factor to predict SSI development, along with open surgery. Conclusions Gram staining diagnosis of bile infection in an early cholecystectomy for AC is useful for predicting postoperative SSI development, which should benefit postoperative management.
    Type of Medium: Online Resource
    ISSN: 1868-6974 , 1868-6982
    URL: Issue
    URL: Article
    DOI: 10.1002/jhbp.v27.12
    DOI: 10.1002/jhbp.790
    Language: English
    Publisher: Wiley
    Publication Date: 2020
    detail.hit.zdb_id: 2536390-6
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  • 4
    Online Resource
    Online Resource
    Emergency abdominal surgeries remain unchanged in the COVID‐19 affected environment: A single‐center experience at a community hospital in Japan
    Wiley ; 2021
    In:  Acute Medicine & Surgery Vol. 8, No. 1 ( 2021-01)
    Details
    In: Acute Medicine & Surgery, Wiley, Vol. 8, No. 1 ( 2021-01)
    Abstract: This study assessed whether emergency abdominal surgeries were changed in the coronavirus disease (COVID‐19)‐affected environment at a community hospital in Japan, with the goal of planning and preparing hospital resources against the further spread of COVID‐19. Methods A total of 179 patients who underwent emergency abdominal surgery over 4 months during the pandemic (1 March, 2020 to 30 June, 2020) and a control period (1 March, 2019 to 30 June, 2019) were enrolled in this retrospective study. Patient demographics, hospital visiting patterns (visit time, ambulance transport, and duration of symptom onset to hospital visit), severity of patients’ condition, and surgical characteristics were compared between the two periods. Results The number of patients undergoing emergency abdominal surgery during the pandemic did not decrease in comparison to the control period (89 patients versus 90 patients). The duration of symptom onset to hospital visit during the pandemic was not prolonged compared to the control period. Other hospital visiting patterns, severity of patients’ condition, and surgical characteristics were also similar in both periods. Conclusion Although the situation of the pandemic was different between countries and regions, the number of emergency surgeries in our hospital remained unchanged, and those patients visited the emergency room no later than usual.
    Type of Medium: Online Resource
    ISSN: 2052-8817 , 2052-8817
    URL: Issue
    URL: Article
    DOI: 10.1002/ams2.v8.1
    DOI: 10.1002/ams2.623
    Language: English
    Publisher: Wiley
    Publication Date: 2021
    detail.hit.zdb_id: 2751184-4
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  • 5
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    Online Resource
    Progression from early to advanced stage of immune‐related cholangitis
    Wiley ; 2022
    In:  Hepatology Research Vol. 52, No. 10 ( 2022-10), p. 888-892
    Details
    In: Hepatology Research, Wiley, Vol. 52, No. 10 ( 2022-10), p. 888-892
    Abstract: We report a rare case of immune‐related cholangitis in which the natural course could be demonstrated. Case Presentation Eight courses of pembrolizumab maintenance therapy were given as first‐line treatment for squamous cell lung cancer; however, the patient was subsequently hospitalized due to a rapid increase in hepatobiliary enzymes. On endoscopic ultrasound, the common bile duct was dilated to 11 mm, and the wall, throughout its length from the papilla, was thickened. Endoscopic retrograde cholangiopancreatography showed no obvious stenosis in the lower bile duct; however, a parapapillary diverticulum was found, and papillary incision and bile duct plastic stent insertion were carried out. However, the liver disorder did not improve and overt jaundice appeared subsequently; therefore, an immune‐related cholangitis was suspected, and prednisolone (PSL) 35 mg/day was introduced from day 59 of admission. Following PSL initiation, a decrease in serum bilirubin level was observed; however, significant decrease was not observed in alkaline phosphatase. Given the history of recurrent infectious cholangitis, magnetic resonance cholangiopancreatography was carried out on day 70 of admission. The intrahepatic bile duct showed stenosis and dilated findings, which was considered to be a factor for repeated infectious cholangitis. Conclusion No previous case reports have described the changes and progression in bile duct images in immune‐related adverse events. Therefore, this case is noteworthy for considering the progression of immune‐related cholangitis.
    Type of Medium: Online Resource
    ISSN: 1386-6346 , 1872-034X
    URL: Issue
    URL: Article
    DOI: 10.1111/hepr.v52.10
    DOI: 10.1111/hepr.13817
    Language: English
    Publisher: Wiley
    Publication Date: 2022
    detail.hit.zdb_id: 2006439-1
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  • 6
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    Online Resource
    Clinical implication of immune checkpoint inhibitor on the chronic hepatitis B virus infection
    Wiley ; 2022
    In:  Hepatology Research Vol. 52, No. 9 ( 2022-09), p. 754-761
    Details
    In: Hepatology Research, Wiley, Vol. 52, No. 9 ( 2022-09), p. 754-761
    Abstract: The risk of hepatitis B virus (HBV) reactivation with immune checkpoint inhibitors (ICIs) is an important issue that has not yet been fully investigated. ICI is also expected to have an antiviral effect on HBV due to its immune tolerance inhibitory effect. We herein investigated the risk of HBV reactivation and the antiviral effect of ICI administration. Methods This study included 892 patients on ICIs between September 2014 and May 2021 at our hospital. The frequency of HBV reactivation and antiviral effects were investigated. Results Among the 892 patients who underwent ICI, 27 were hepatitis B surface antigen (HBsAg) positive. HBV reactivation was evaluated in 24 cases, among which 4.1% (1/24) had HBV reactivation. Nucleic acid analog prophylaxis was not administered to patients with reactivation. In a study of 15 cases, the amount of HBsAg decreased from baseline; 2.18 ± 0.77 log to 48 weeks later; 1.61 ± 1.38 log ( p  = 0.17). Forty‐eight weeks after the start of ICI, disappearance of HBsAg was observed in two out of 15 cases (13.3%), and one case each with and without nucleic acid analog. Conclusion In rare cases, HBsAg‐positive patients may be reactivated by ICI administration. On the other hand, when ICI is administered, it is expected to have an antiviral effect on HBV due to its immune tolerance inhibitory effect, and future drug development is expected.
    Type of Medium: Online Resource
    ISSN: 1386-6346 , 1872-034X
    URL: Issue
    URL: Article
    DOI: 10.1111/hepr.v52.9
    DOI: 10.1111/hepr.13798
    Language: English
    Publisher: Wiley
    Publication Date: 2022
    detail.hit.zdb_id: 2006439-1
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  • 7
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    Online Resource
    Vascular anatomical study of persistent descending mesocolon in patients undergoing laparoscopic surgery for colorectal cancer
    Wiley ; 2023
    In:  Asian Journal of Endoscopic Surgery Vol. 16, No. 3 ( 2023-07), p. 465-472
    Details
    In: Asian Journal of Endoscopic Surgery, Wiley, Vol. 16, No. 3 ( 2023-07), p. 465-472
    Abstract: Persistent descending mesocolon (PDM) is a rare congenital atypia of fixation of the descending colon, and currently, very few detailed studies exist on its vascular anatomy. This study was conducted to evaluate the features of the vascular anatomy of PDM to help avoid intraoperative lethal injury and subsequent postoperative complications in laparoscopic colorectal surgery. Methods We retrospectively analyzed the data of 534 patients who underwent laparoscopic left‐sided colorectal surgery. PDM was diagnosed using preoperative axial computed tomography (CT) view. The vascular anatomical features were compared between PDM and non‐PDM cases based on three‐dimensional (3D)‐CT angiography findings. Additionally, the perioperative short‐term outcomes of laparoscopic surgery in the 534 patients were also compared between PDM and non‐PDM cases. Results Of the total 534 patients, 13 patients (2.4%) presented with PDM. No branching pattern of the inferior mesenteric artery (IMA) specific to PDM was found. In the running direction of the IMA and sigmoidal colic artery (SA), the midline‐shift of IMA and the right‐shift of SA were significantly more in PDM than in non‐PDM cases, respectively (38.5% vs. 2.5%, P  ≤ .0001; 61.5% vs. 4.6%, P  ≤ .0001). The perioperative short‐term outcomes of laparoscopic surgery in the 534 patients were similar between PDM and non‐PDM cases. Conclusion Because changes in the direction of the vascular running are often observed due to adhesions and shortening of the mesentery in PDM cases, performing a detailed preoperative evaluation of vascular anatomy using imaging modalities such as 3D‐CT angiography is important.
    Type of Medium: Online Resource
    ISSN: 1758-5902 , 1758-5910
    URL: Issue
    URL: Article
    DOI: 10.1111/ases.v16.3
    DOI: 10.1111/ases.13203
    Language: English
    Publisher: Wiley
    Publication Date: 2023
    detail.hit.zdb_id: 2492135-X
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  • 8
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    Online Resource
    Rabbit Ileal Loop Responses to Clostridium sordellii Strains
    Wiley ; 1983
    In:  Microbiology and Immunology Vol. 27, No. 9 ( 1983-09), p. 807-809
    Details
    In: Microbiology and Immunology, Wiley, Vol. 27, No. 9 ( 1983-09), p. 807-809
    Type of Medium: Online Resource
    ISSN: 0385-5600
    URL: Issue
    URL: Article
    DOI: 10.1111/mim.1983.27.issue-9
    DOI: 10.1111/j.1348-0421.1983.tb00646.x
    Language: English
    Publisher: Wiley
    Publication Date: 1983
    detail.hit.zdb_id: 2102145-4
    SSG: 12
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  • 9
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    Deformation Mechanism of Fine‐Grained Magnesium Aluminate Spinel Prepared Using an Alkoxide Precursor
    Wiley ; 2000
    In:  Journal of the American Ceramic Society Vol. 83, No. 3 ( 2000-03), p. 645-647
    Details
    In: Journal of the American Ceramic Society, Wiley, Vol. 83, No. 3 ( 2000-03), p. 645-647
    Abstract: Polycrystalline MgAl 2 O 4 spinel with high purity and stoichiometric composition was prepared using alkoxide precursors. The average grain size of the polycrystal was fine (1.7 μm). The deformation mechanism of the polycrystal was investigated in air at temperatures of 1300°–1400°C. At 1300°C, oxygen lattice diffusion controlled the deformation, despite the fine grain size; however, increases in the temperature and applied stress caused cavities to nucleate and grow. Spinel possessed better creep resistance than alumina of comparative grain size. The effective diffusion coefficient was determined as follows: [formula omitted]
    Type of Medium: Online Resource
    ISSN: 0002-7820 , 1551-2916
    URL: Issue
    URL: Article
    DOI: 10.1111/jace.2000.83.issue-3
    DOI: 10.1111/j.1151-2916.2000.tb01246.x
    RVK:
    VA 1120
    Language: English
    Publisher: Wiley
    Publication Date: 2000
    detail.hit.zdb_id: 2008170-4
    detail.hit.zdb_id: 219232-9
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  • 10
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    Relationship between the morphology of osteophytes and cartilage lesions in anterior ankle impingement in athletes: a cross‐sectional study
    Wiley ; 2023
    In:  Journal of Foot and Ankle Research Vol. 16, No. 1 ( 2023-01)
    Details
    In: Journal of Foot and Ankle Research, Wiley, Vol. 16, No. 1 ( 2023-01)
    Abstract: The present study aimed to describe the frequency and severity of tram‐track lesions in anterior ankle impingement in athletes and to evaluate the association between osteophyte morphology and severity of tram‐track lesions, the distinctive cartilage lesions associated with tibial osteophytes in anterior ankle impingement syndrome. Methods We evaluated 34 athletes who underwent arthroscopic osteophyte resection for anterior ankle impingement between January 2017 and March 2021. Results We found tram‐track lesions in 26 athletes (76.5%). Arthroscopic findings revealed the distribution of the International Cartilage Repair Society grades of tram‐track lesions (grade 0, eight; grade 1, seven; grade 2, ten; grade 3, nine; grade 4, zero). These findings indicate that athletes with anterior ankle impingement syndrome may have more severe cartilage lesions than non‐athletes. There was a positive correlation between the International Cartilage Repair Society grade and osteophyte size (r = 0.393, p = 0.021). We divided athletes into two groups according to the presence or absence of osteophyte protrusion into the joint space. Osteophyte protrusion was present in 14 athletes (41.2%). All athletes in the protrusion‐type group had tram‐track lesions; seven (50%) had International Cartilage Repair Society grade 3. The protrusion‐type group's International Cartilage Repair Society grade was significantly higher than that of the non‐protrusion‐type group ( p = 0.008). The osteophyte sizes in the two groups were not significantly different ( p = 0.341). Conclusions Based on these findings, osteophyte protrusion should be assessed when an indication of arthroscopic treatment for anterior ankle impingement syndrome is considered, particularly in athletes.
    Type of Medium: Online Resource
    ISSN: 1757-1146 , 1757-1146
    URL: Article
    DOI: 10.1186/s13047-023-00633-z
    Language: English
    Publisher: Wiley
    Publication Date: 2023
    detail.hit.zdb_id: 2440706-9
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