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  • 1
    In: Medical Physics, Wiley, Vol. 46, No. 8 ( 2019-08), p. 3543-3554
    Abstract: Image‐guided spine surgery and preoperative computer‐assisted planning provide spine surgeons with tools to improve the safety, accuracy, and reliability of pedicle screw placement. The purpose of this study is to demonstrate a computer‐assisted pedicle screw placement planning tool in comparison to screws as delivered by a spine surgeon. Methods We describe a novel computer‐assisted tool for preoperative pedicle screw placement planning in computed tomography (CT) images, designed with respect to the vertebral shape and structure, and augmented with respect to the considerations of surgical practice. The approach is based on three‐dimensional (3D) modeling of the vertebral body and pedicles, and planning of the pedicle screw size and insertion trajectory by maximizing the screw fastening strength, evaluated through CT‐inferred bone density maps. The approach is augmented by yielding screw plans consistent with the straight‐forward surgical technique of aligning screws parallel to vertebral endplates, and the screw entry points following the spinal curvature to facilitate rod attachment. For a cohort of 25 patients, placement plans were retrospectively obtained for 204 pedicle screws with the computer‐assisted tool from preoperative CT images, while reference trajectories of inserted pedicle screws were reconstructed in 3D from postoperative biplanar radiographs. Results The best performing version of the computer‐assisted tool achieved clinically acceptable preoperative pedicle screw placement plans in 96.6% of the cases, while the comparison to the postoperative reconstructions resulted in 3.4 ± 2.5 mm for the screw entry point location, 2.7 ± 1.6 mm for the screw crossing point location, and 7.4 ± 5.3 ∘ for the screw sagittal inclination (mean absolute difference ± standard deviation). Conclusion Quantitative comparison revealed that the preoperative placement plans are consistent with the postoperative results, and that the computer‐assisted tool integrating bone density and surgical constraints can successfully incorporate important aspects of pedicle screw placement. The results therefore confirm the accuracy of the tool prior to being integrated in an image‐guidance system.
    Type of Medium: Online Resource
    ISSN: 0094-2405 , 2473-4209
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2019
    detail.hit.zdb_id: 1466421-5
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  • 2
    Online Resource
    Online Resource
    Wiley ; 2016
    In:  Journal of Paediatrics and Child Health Vol. 52, No. 8 ( 2016-08), p. 802-808
    In: Journal of Paediatrics and Child Health, Wiley, Vol. 52, No. 8 ( 2016-08), p. 802-808
    Abstract: Back pain in children is underdiagnosed and increases incidence in adolescence. A systematic approach can diagnose the most common causes: trauma, structural deformities, inflammatory diseases, infection and malignancy.
    Type of Medium: Online Resource
    ISSN: 1034-4810 , 1440-1754
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2016
    detail.hit.zdb_id: 2007577-7
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  • 3
    In: Health Science Reports, Wiley, Vol. 7, No. 4 ( 2024-04)
    Abstract: Migraine is a prevalent neurological disorder characterized by recurring episodes of debilitating headache accompanied by associated symptoms and sleep disorders. This study aims to investigate migraine‐associated symptoms in female migraineurs within the Syrian population and the relation between migraines and sleep issues. Methods A questionnaire‐based cross‐sectional observational study was conducted among the Syrian population. A total of 1009 women were enrolled in this study, including women without a history of migraine (Control group) and migraineurs (Case group) who had received a diagnosis of migraine from a hospital or private clinic. Data about migraine‐related symptoms, including tingling, visual disturbances, Nausea/Vomiting, and epileptic seizures as well as sleep‐related symptoms such as interrupted sleep, frequent awakenings, insomnia, snoring, and narcolepsy were gathered. Chi‐square test was used to examine the relation between migraines and sleep issues. Results A total of 1009 women were enrolled in this study including 531 migraineurs and 478 healthy women. The study revealed that the most commonly experienced symptoms during migraine attacks were nausea/vomiting and visual disturbances, followed by tingling. Total Unduplicated Reach and Frequency analysis showed that visual disturbances and nausea/vomiting were the two most frequent symptoms that co‐occurred during migraine attacks. The study also demonstrated a significant relationship between snoring, insomnia, and narcolepsy with migraine ( p = 0.038), with these sleep disorders being more prevalent among migraineurs. Conclusion The findings indicate a significant association between migraines and sleep disorders, with migraineurs being at a significantly higher risk of experiencing poor sleep quality compared to healthy women. Addressing sleep disorders is crucial in managing patients with migraines. This study is the first of its kind in the Syrian population, providing valuable insights into the symptoms and sleep disorders associated with migraines in this population.
    Type of Medium: Online Resource
    ISSN: 2398-8835 , 2398-8835
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2024
    detail.hit.zdb_id: 2927182-4
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