In:
FEBS Letters, Wiley, Vol. 224, No. 2 ( 1987-11-30), p. 385-390
Abstract:
The free modulator subunit of the ATP,Mg‐dependent phosphatase is phosphorylated up to 1 mol per mol by casein kinase‐1, up to 1.85 mol per mol after dephosphorylation by the PCS H1 phosphatase, but 10‐fold less when purified in the presence of NaF, suggesting an in vivo phosphorylation of the casein kinase‐1 sites. Peptide mapping of 32 P‐modulator labeled by casein kinase‐1 or ‐2 shows a different phosphorylation pattern. Phosphorylation of the inactive phosphatase by casein kinase‐1 prevents the subsequent kinase F A ‐mediated activation, while it does not impair the activated phosphatase.
Type of Medium:
Online Resource
ISSN:
0014-5793
,
1873-3468
DOI:
10.1016/0014-5793(87)80489-1
Language:
English
Publisher:
Wiley
Publication Date:
1987
detail.hit.zdb_id:
1460391-3
SSG:
12
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