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  • Wiley  (12)
  • 1
    Online Resource
    Online Resource
    Wiley ; 2017
    In:  The Journal of Dermatology Vol. 44, No. 11 ( 2017-11), p. 1255-1261
    In: The Journal of Dermatology, Wiley, Vol. 44, No. 11 ( 2017-11), p. 1255-1261
    Abstract: Keratitis–ichthyosis–deafness ( KID ) syndrome is a rare genodermatosis. It is mostly associated with mutations of the connexin 26 gene, resulting in keratitis, erythrokeratoderma and neurosensory deafness. In addition to the clinical triad, the KID syndrome patients are at high risk for infectious complications, while the mechanisms are poorly understood. In the present article, we described an Asian case of KID syndrome accompanied by fungal infection. The present study was designed to define the mutation type, and further to explore the interaction between the innate immunity response and the infectious complication of KID syndrome. Genomic DNA was extracted from peripheral blood for mutation analysis. Isolation and identification of the species were carried out to confirm the infectious microorganism. Three biopsy specimens from different parts of the body (right thigh, abdomen and forehead, respectively) were carried out for histopathological and immunohistochemical analysis. Furthermore, quantitative polymerase chain reaction ( PCR ) was carried out to study the expression of Toll‐like receptor 2 ( TLR 2) on the epidermis of the right thigh. We identified a mutation (p.G12R) in the GJB 2 gene in this patient with Trichophyton rubrum infection. Immunohistochemistry staining revealed a lower expression of TLR 2 and no significant difference in TLR 4. Meanwhile, PCR showed a relatively slight increase of TLR 2 RNA expression. These results indicated that GJB 2 mutation (p.G12R) in this case of KID syndrome, which was susceptible to T. rubrum infection, might be attributed to a limited native immune response.
    Type of Medium: Online Resource
    ISSN: 0385-2407 , 1346-8138
    URL: Issue
    RVK:
    Language: English
    Publisher: Wiley
    Publication Date: 2017
    detail.hit.zdb_id: 2222121-9
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  • 2
    In: The Journal of Dermatology, Wiley, Vol. 42, No. 12 ( 2015-12), p. 1179-1182
    Abstract: Emmonsia pasteuriana is a thermally dimorphic fungus identified in very few human cases. Here, we report a case of a 43‐year‐old male renal transplant patient from China presenting with multiple painful skin eruptions on his head, nose and left thigh, later accompanied by respiratory failure. Histopathology of the biopsy collected from the left thigh upper ulcer and occipital nodule both demonstrated chronic inflammation with granuloma formation and yeast‐like elements. Emmonsia pasteuriana was cultured from two biopsy specimens and their identity was confirmed by sequencing of the r DNA internal transcribed spacer. The patient in intensive care showed marked clinical improvement with antifungal treatment.
    Type of Medium: Online Resource
    ISSN: 0385-2407 , 1346-8138
    URL: Issue
    RVK:
    Language: English
    Publisher: Wiley
    Publication Date: 2015
    detail.hit.zdb_id: 2222121-9
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  • 3
    In: CNS Neuroscience & Therapeutics, Wiley, Vol. 27, No. 7 ( 2021-07), p. 743-752
    Abstract: The neurovascular unit (NVU) is emerging as a potential therapeutic target in neurological conditions, such as stroke, brain injury, Alzheimer's disease, and Parkinson's disease; meanwhile, stroke is the second leading cause of death globally. The purpose of the study is to analyze the most influential articles, authors, countries, and topics in the role of NVU in stroke. Methods The Web of Science (WoS) database was used for bibliometric analysis using the search terms “Stroke” and “Neurovascular unit” on January 1st, 2021. Data were extracted from the WoS database to identify collaborations between authors, countries, organizations, and keywords using VOSviewer (1.6.16 mac). Two bibliometric indicators, the activity index (AI) and category normalized citation impact (CNCI), were computed. The keywords of bursts were also identified by CiteSpace. Results A total of 770 articles were analyzed by VOSviewer. AIs and CNCIs were computed of the eighteen countries according to VOSviewer co‐authorship analysis results. The majority of authors mainly came from the United States and Japan. Romania, Hungary, and Poland have emerged as rising‐star countries. In the 100 most‐cited articles, the number of citations ranged from 1873 to 69, with a total of 15,758 citations. Most articles were published in 2011 and 2012 ( n  = 13 each), followed by 2009 ( n  = 11) and 2013, 2014, and 2015 ( n  = 8 each). Stroke and Journal of Cerebral Blood Flow and Metabolism were the two top journals. EH Lo from Harvard University/ Massachusetts General Hospital was the top first author and corresponding author. Harvard University/Massachusetts General Hospital was the most productive affiliated institution with 15 publications. Conclusion There has been growing attention and efforts made in the field of stroke and NVU. The merit of the above findings may help to shape the research policy in ischemic stroke both at the country and institutional level.
    Type of Medium: Online Resource
    ISSN: 1755-5930 , 1755-5949
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2021
    detail.hit.zdb_id: 2423467-9
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  • 4
    In: Mycoses, Wiley, Vol. 59, No. 10 ( 2016-10), p. 662-667
    Abstract: A first auricular case of chromoblastomycosis due to Fonsecaea nubica is reported in a 42‐year‐old Chinese male. He presented a slightly verrucous, erythematous plaque on his right auricle which had gradually extended over a 10‐year period, and the patient reported a history of dog flea sting before onset of the lesions. Diagnosis was based on histopathological and mycological examination of clinical samples, which revealed muriform cells. Identification of the aetiological agent was assessed by morphological characteristics and confirmed at species level by sequencing of the rDNA internal transcribed spacer ( ITS ). The patient showed marked clinical improvement after 3 months combination therapy with itraconazole and terbinafine. The possible mode of transmission of auricular chromoblastomycosis is discussed.
    Type of Medium: Online Resource
    ISSN: 0933-7407 , 1439-0507
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2016
    detail.hit.zdb_id: 2020780-3
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  • 5
    Online Resource
    Online Resource
    Wiley ; 2023
    In:  Microwave and Optical Technology Letters
    In: Microwave and Optical Technology Letters, Wiley
    Abstract: The antennas that share radiators with solar cells are applicable to collect energy and integrate radio frequency functions. In this paper, a solar cell integrated multiband antenna is proposed on the basis of Vivaldi antenna structure. Unlike prior research, it has the capacity to reconfigure working frequencies and radiation performance of the antenna through optical control of the solar cell. The purpose of reconfiguration is achieved by means of two switching diodes placed between the differential Vivaldi radiator and conducted via biasing from the solar cell. The integrated solar cell functions both as part of the radiator and as the biasing source for switching diodes. According to the simulation and measurement results, the antenna performs consistently at around 5 GHz, while the radiation performance can be reconfigured at 1.16 and 3 GHz under illumination. In this way, the proposed antenna can fulfill various functions such as green energy collection, wireless communication, and light detection, which makes it applicable in the Internet of Things for low‐power wireless sensor terminal.
    Type of Medium: Online Resource
    ISSN: 0895-2477 , 1098-2760
    Language: English
    Publisher: Wiley
    Publication Date: 2023
    detail.hit.zdb_id: 2000574-X
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  • 6
    In: River, Wiley, Vol. 2, No. 2 ( 2023-05), p. 239-248
    Abstract: Quality and stability are the basic characteristics of ecosystems, reflecting their structure, process, functional integrity, ability to resist disturbance, self‐regulation, and dynamic balance. The quantitative description of ecosystem quality and stability is an indispensable and important task to promote the ecological protection and high‐quality development of the Yellow River Basin as a major national strategy. In this study, an index evaluation system was constructed from the perspective of system governance, considering the special characteristics of the Yellow River Basin, and an entropy weight model was used to establish a multi‐indicator long time series ecosystem quality evaluation index (EQI) to quantitatively describe the ecological quality changes in the Yellow River Basin over 40 years. The dissipative structure theory and Brussels apparatus model were used to establish quantitative indicators and methods, and provide ideas for the study of ecosystem homeostasis transformation in the Yellow River basin. This study found that: (1) the average EQI value of the Yellow River Basin ecosystem for 40 years was 63.96, the maximum and minimum values were 69.65 and 59.45, respectively; the overall quality showed an oscillating trend of improvement, with an annual increase of 0.03, and the spatial distribution was better in the downstream than in the midstream, and in the midstream than in the upstream; (2) The key factors influencing the system changed gradually from the total water consumption and total annual precipitation in the basin in the early stage to the average income of residents in the last 10 years. (3) The system steady‐state transition force values from 1980 to 2019 were all 〈 0, the steady‐state conversion force of the Yellow River Basin ecosystem was low, but the overall trend was oscillating upward, and the overall trend was getting closer to the critical condition of steady‐state conversion.
    Type of Medium: Online Resource
    ISSN: 2750-4867 , 2750-4867
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2023
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  • 7
    In: Advanced Functional Materials, Wiley, Vol. 33, No. 52 ( 2023-12)
    Abstract: Effective thermal superinsulation in extremely high temperatures (EHT) is crucial for aerospace, industrial, and civilization activities. However, current strategies relying on ceramic materials face limitations due to their high thermal conductivity and brittleness in specific conditions. In this study, a feasible and scalable method for synthesizing a flexible, lightweight, and transformable fire‐reborn silica‐alumina hybrid ceramic aerogel (FR‐SACA) is presented, which is achieved by rearranging silica aerogel microparticles and Al 2 O 3 ceramic fibers using a self‐sacrifice polymer, resulting in a bio‐inspired bird nest structured FR‐SACA. The SACA exhibits exceptional properties, including an ultra‐low density of 0.01 g cm −3 , a low thermal conductivity of 0.029 W m −1  K −1 , and a reversible compression of up to 80%. Notably, a 20 mm‐thick FR‐SACA demonstrates a remarkable temperature reduction of 1179.6 °C when exposed directly to a 1300 °C flame, suggesting its potential as a thermal superinsulation material in EHT environments. Furthermore, the transformability of SACA enables in situ fabrication on surfaces with diverse heteromorphic structures, such as flat, bent, and angled shapes, thereby providing thermal superinsulation for various constructions. The Phoenix Nirvana process opens up new possibilities for synthesizing ceramic aerogels with desirable flexibility and adaptive properties, facilitating effective thermal management under extreme conditions.
    Type of Medium: Online Resource
    ISSN: 1616-301X , 1616-3028
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2023
    detail.hit.zdb_id: 2029061-5
    detail.hit.zdb_id: 2039420-2
    SSG: 11
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  • 8
    In: Molecular Nutrition & Food Research, Wiley, Vol. 65, No. 16 ( 2021-08)
    Abstract: Probiotics are promising in mitigating drug‐induced liver injury in animal experiments. However, the clinical evidence is absent. The objective is to investigate the effect of adjunctive Lactobacillus casei on tuberculosis‐drug‐induced liver injury. Methods and results A post hoc analysis is conducted for a previous randomized controlled trial. The trial is registered at the Chinese Clinical Trial Registry (No. ChiCTR‐IOR‐17013210). Four hundred twenty nine patients are allocated to receive standard tuberculosis therapy alone (control group), or together with 1 × 10 10 colony‐forming units (CFU) per day (low‐dose group), or 2 × 10 10 CFU per day of L. casei (high‐dose group) during tuberculosis treatment. The L. casei supplementation significantly reduced the incidence of the abnormal increase of cholestasis‐related liver indices including alkaline phosphatase ( p = 0.024) and bilirubin ( p = 0.013). Plasma lipopolysaccharide ( p = 0.02), intestinal permeability biomarkers including zonula occludens‐1 ( p = 0.001) and intestinal fatty acid binding protein ( p = 0.002) are significantly reduced. The gut microbiota composition is dramatically altered with a reduction of Bacteroidetes ( p 〈 0.001) and a corresponding increase of Actinobacteria ( p 〈 0.001) and Firmicutes ( p = 0.003). Conclusions L. casei supplementation is beneficial for suppressing abnormally elevated cholestasis‐related liver indices during tuberculosis treatment, which may be related to its modification on blood lipopolysaccharide, intestinal barrier function, and gut microbiota.
    Type of Medium: Online Resource
    ISSN: 1613-4125 , 1613-4133
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2021
    detail.hit.zdb_id: 2160372-8
    SSG: 12
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  • 9
    In: Molecular Nutrition & Food Research, Wiley, Vol. 65, No. 16 ( 2021-08)
    Type of Medium: Online Resource
    ISSN: 1613-4125 , 1613-4133
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2021
    detail.hit.zdb_id: 2160372-8
    SSG: 12
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  • 10
    Online Resource
    Online Resource
    Wiley ; 2020
    In:  Business Strategy and the Environment Vol. 29, No. 5 ( 2020-07), p. 1887-1898
    In: Business Strategy and the Environment, Wiley, Vol. 29, No. 5 ( 2020-07), p. 1887-1898
    Abstract: Along with the concept of circular economy growing worldwide, circular business models (CBMs) have been receiving ever greater attention in both the business sector and academia. However, the existing literature on the CBM is scattered and fragmented; this study offers an integrated firm‐level framework to link CBM typologies, the circular economy transition process, and relevant tools for CBM development and clarifies the positioning and roles of those tools in the process. In response to the fragmentation issue, results of this study are presented in three subtopics: (a) CBM typologies and archetypes, (b) transition guidelines, and (c) major analytical tools for CBM research. The roles and functions of CBM typologies and tools were integrated in different stages of the transition process, and the challenges and shortfalls for CBM research in the various stages were identified. This work lays the foundation for future operational studies.
    Type of Medium: Online Resource
    ISSN: 0964-4733 , 1099-0836
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2020
    detail.hit.zdb_id: 2025936-0
    detail.hit.zdb_id: 1127954-0
    SSG: 3,2
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