GLORIA

GEOMAR Library Ocean Research Information Access

X

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Online Resource
    Online Resource
    Ideal cardiovascular health metrics and the risk of non‐alcoholic fatty liver disease: A cross‐sectional study in northern China
    Wiley ; 2019
    In:  Liver International Vol. 39, No. 5 ( 2019-05), p. 950-955
    Details
    In: Liver International, Wiley, Vol. 39, No. 5 ( 2019-05), p. 950-955
    Abstract: The components of ideal cardiovascular health (CVH) metrics have been shown to be associated with non‐alcoholic fatty liver disease (NAFLD). The present study aimed to determine the association between ideal CVH metrics and NAFLD. Methods A total of 10,511 participants (47.26% men) aged 18 to 92 years were selected from the Jidong and Kailuan communities. Ideal CVH was based on 7 ideal CVH metrics: smoking, body mass index (BMI), physical activity, diet, total cholesterol, blood pressure and fasting blood glucose. NAFLD was determined by abdominal ultrasonography. All participants underwent questionnaire assessments and clinical and laboratory examinations. Logistic regression models were used to analyse the relationship of CVH metrics and the number of ideal CVH metrics with NAFLD. Results The prevalence rates of NAFLD by CVH summary score quartiles were 64.38% (2,015/3,130), 50.16% (786/1,567), 33.28% (1,194/3,588) and 20.89% (465/2,226). Participants in the highest quartile showed a lower odds ratio (OR) than those in the lowest quartile (fully adjusted OR: 0.17, 95% CI: 0.17‐0.20, P   〈  0.001). Similar results were observed in subjects stratified by sex and age (45 years). The ORs were progressively decreased with an increased number of ideal CVH metrics (all P   〈  0.001). Conclusions NAFLD was significantly associated with both the summary score of CVH metrics and the number of ideal CVH metrics. The combined evaluation of ideal CVH may contribute to the prevention of NAFLD.
    Type of Medium: Online Resource
    ISSN: 1478-3223 , 1478-3231
    URL: Issue
    URL: Article
    DOI: 10.1111/liv.2019.39.issue-5
    DOI: 10.1111/liv.14060
    Language: English
    Publisher: Wiley
    Publication Date: 2019
    detail.hit.zdb_id: 2124684-1
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 2
    Online Resource
    Online Resource
    Copper‐Catalyzed Stepwise Aerobic Oxidation/N‐Arylation from Benzothiazole
    Wiley ; 2024
    In:  European Journal of Organic Chemistry Vol. 27, No. 1 ( 2024-01-02)
    Details
    In: European Journal of Organic Chemistry, Wiley, Vol. 27, No. 1 ( 2024-01-02)
    Abstract: We report herein an efficient synthesis of 3‐arylbenzothiazolin‐2‐one compounds. First, substituted benzothiazoles can be smoothly oxidized to benzothiazolin‐2‐one derivatives in the presence of CuCl 2 and trifluoroacetic anhydride. Secondly, the Cu 2 S‐catalyzed N‐arylation of benzothiazolin‐2‐one with arylboronic acids yields a series of novel 3‐aryl benzothiazolin‐2‐one derivatives. The method provides good yields for a variety of substrates and shows good compatibility with functional groups. The usefulness of the skeleton was further illustrated by the derivatization of 3‐aryl‐benzothiazolin‐2‐one. Mechanistic studies suggest that the oxidation of benzothiazole may undergo a free radical reaction process.
    Type of Medium: Online Resource
    ISSN: 1434-193X , 1099-0690
    URL: Issue
    URL: Article
    DOI: 10.1002/ejoc.v27.1
    DOI: 10.1002/ejoc.202301108
    RVK:
    VA 4073
    Language: English
    Publisher: Wiley
    Publication Date: 2024
    detail.hit.zdb_id: 1475010-7
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 3
    Online Resource
    Online Resource
    NH 3 ‐SCR Performance Enhancement of LDHs‐Based NiMnFe‐Mixed Oxides by Two‐Phase Coexistence and Cooperation
    Wiley ; 2019
    In:  ChemistrySelect Vol. 4, No. 32 ( 2019-08-29), p. 9488-9496
    Details
    In: ChemistrySelect, Wiley, Vol. 4, No. 32 ( 2019-08-29), p. 9488-9496
    Abstract: Mixed oxides with NiMnFe‐LDHs as precursors were synthesized and evaluated as catalysts in selective catalytic reduction of NO with NH 3 (NH 3 ‐SCR). Appropriate calcination temperature was identified to achieve optimal catalyst. The results pronouncedly affirmed that the catalytic performances of the as‐acquired catalysts were vulnerable to calcination temperature, where Ni 3 Mn 1 Fe 1 ‐600 presented preferable DeNO x activity with above 90% NO conversion and 98% N 2 selectivity in the range of 150‐360 °C. Multiple characterizations exhibited that the outstanding DeNO x activity was determined by the coexistence as well as cooperation of NiFe 2 O 4 spinel and Ni 6 MnO 8 phase, which could contribute more surface active sites, and synergetic effect arising from the electron transfer between Ni, Mn ions and Ni, Fe ions. Furthermore, a more rapid redox cycle and optimal DeNO x performance were resultantly accomplished.
    Type of Medium: Online Resource
    ISSN: 2365-6549 , 2365-6549
    URL: Issue
    URL: Article
    DOI: 10.1002/slct.v4.32
    DOI: 10.1002/slct.201902337
    Language: English
    Publisher: Wiley
    Publication Date: 2019
    detail.hit.zdb_id: 2844262-3
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 4
    Online Resource
    Online Resource
    Pd‐Catalyzed Regioselective Olefination of N ‐Tosylhydrazones with Benzyl Bromides
    Wiley ; 2020
    In:  ChemistrySelect Vol. 5, No. 25 ( 2020-07-07), p. 7396-7399
    Details
    In: ChemistrySelect, Wiley, Vol. 5, No. 25 ( 2020-07-07), p. 7396-7399
    Abstract: A palladium‐catalyzed regioselective olefination of cycloalkylphenylmethylene N ‐tosylhydrazones and benzyl bromide was developed. A series of E ‐type tri‐substituted olefin compounds were obtained in 43–95% through the highly selective β ‐H elimination. The results showed that the β ‐H at the benzyl position took precedence over the β ‐H at the cycloalkyl position for the alkylpalladium intermediate, avoiding the formation of tetra‐substituted olefins. High regioselectivity, wide substrate scope, and good functional group tolerance are the advantages of this reaction.
    Type of Medium: Online Resource
    ISSN: 2365-6549 , 2365-6549
    URL: Issue
    URL: Article
    DOI: 10.1002/slct.v5.25
    DOI: 10.1002/slct.202002010
    Language: English
    Publisher: Wiley
    Publication Date: 2020
    detail.hit.zdb_id: 2844262-3
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 5
    Online Resource
    Online Resource
    Areas of C hina predicted to have a suitable climate for A noplophora chinensis under a climate‐warming scenario
    Wiley ; 2014
    In:  Entomologia Experimentalis et Applicata Vol. 153, No. 3 ( 2014-12), p. 256-265
    Details
    In: Entomologia Experimentalis et Applicata, Wiley, Vol. 153, No. 3 ( 2014-12), p. 256-265
    Abstract: A noplophora chinensis ( F orster) ( C oleoptera: C erambycidae) is an A1 class quarantine pest, native to C hina, J apan, and N orth K orea. The A . chinensis outbreak in C hina has severely affected the local environment and economic development. This study investigates potential areas in C hina with suitable climate for A .  chinensis using historical climate data (1971–2000) and future climate‐warming estimates generated by CLIMEX 1.1. These future estimates are based on simulated climate data (2010–2039) provided by the Tyndall Centre for Climate Change Research ( TYN SC 2.0). The results suggest that a wide area of C hina will have a climate suitable for A .  chinensis , and every province may contain some suitable areas for this pest. The predicted areas are distributed primarily in central and southern China, with an estimated distribution range of 18.2–49.5°N and 81.3–135.0°E. Using a global‐warming scenario and predictions based on historical climate data, the areas in China with a climate generally suitable for A . chinensis are predicted to decline, whereas the areas that are highly suitable for A . chinensis are predicted to expand particularly to the northeast and northwest. The estimated distribution range covered 18.2–49.1°N and 73.6–135.0°E. A noplophora chinensis hosts grow in much of C hina; therefore, the pest could possibly establish this entire predicted area. These results support enhanced quarantine and control measures combined with stronger monitoring systems to prevent the spread and export of A . chinensis .
    Type of Medium: Online Resource
    ISSN: 0013-8703 , 1570-7458
    URL: Issue
    URL: Article
    DOI: 10.1111/eea.2014.153.issue-3
    DOI: 10.1111/eea.12247
    RVK:
    WA 15000
    Language: English
    Publisher: Wiley
    Publication Date: 2014
    detail.hit.zdb_id: 2015286-3
    SSG: 12
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 6
    Online Resource
    Online Resource
    The m6A reader YTHDC1 regulates muscle stem cell proliferation via PI4K–Akt–mTOR signalling
    Wiley ; 2023
    In:  Cell Proliferation Vol. 56, No. 8 ( 2023-08)
    Details
    In: Cell Proliferation, Wiley, Vol. 56, No. 8 ( 2023-08)
    Abstract: Muscle stem cells are required for the homeostasis and regeneration of mammalian skeletal muscles. It has been reported that RNA N6‐methyladenosine (m6A) modifications play a pivotal role in muscle development and regeneration. Nevertheless, we know little about which m6A reader regulates mammalian muscle stem cells. Here, we discovered that the m6A reader Ythdc1 is indispensable for mouse skeletal muscle regeneration and proliferation of muscle stem cells. In the absence of Ythdc1, Muscle stem cells in adult mice are unable to exit from quiescence. Mechanistically, Ythdc1 binds to m6A‐modified Pi4k2a and Pi4kb mRNAs to regulate their alternative splicing and thus PI4K–Akt–mTOR signalling. Ythdc1‐null muscle stem cells show a deficiency in phosphatidylinositol (PI) 3,4,5‐trisphosphate, phospho‐Akt and phospho‐S6, which correlates with a failure in exit from quiescence. Our findings connect dynamic RNA methylation to the regulation of PI4K–Akt–mTOR signalling during stem cell proliferation and adult tissue regeneration.
    Type of Medium: Online Resource
    ISSN: 0960-7722 , 1365-2184
    URL: Issue
    URL: Article
    DOI: 10.1111/cpr.v56.8
    DOI: 10.1111/cpr.13410
    Language: English
    Publisher: Wiley
    Publication Date: 2023
    detail.hit.zdb_id: 2019986-7
    SSG: 12
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 7
    Online Resource
    Online Resource
    A novel fiber‐reinforced silicone rubber composite with Al particles for enhanced dielectric and thermal properties
    Wiley ; 2018
    In:  Advances in Polymer Technology Vol. 37, No. 5 ( 2018-09), p. 1507-1516
    Details
    In: Advances in Polymer Technology, Wiley, Vol. 37, No. 5 ( 2018-09), p. 1507-1516
    Abstract: Aluminum (Al) reinforced silicone rubber ( SR ) composites were prepared, and the effects of the content, particle size, shape, and surface modification of Al particles on the dielectric properties and thermal conductivity of the Al/ SR were investigated. Dielectric permittivity, dissipation factor and thermal conductivity of the Al/ SR increase with increasing the filler content. The dissipation factors still remain at a low level at high filler content because of the insulating alumina shell on the surface of core Al. Decrease in particle size and surface modification of Al can increase the dielectric permittivity and thermal conductivity of the Al/ SR composites. Compared with spherical Al/ SR , the flaky Al/ SR composites present higher dielectric permittivity and thermal conductivity. Dielectric permittivity and thermal conductivity of the Al/carbon fiber ( CF )/ SR composites reach 72.1 and 2.01 W/m K at 75 wt% of the total filler content, respectively, suggesting that the ternary composites has potential applications in electromechanical actuators because of their high dielectric permittivity and thermal conductivity but low dissipation factor, and good elasticity.
    Type of Medium: Online Resource
    ISSN: 0730-6679 , 1098-2329
    URL: Issue
    URL: Article
    DOI: 10.1002/adv.2018.37.issue-5
    DOI: 10.1002/adv.21809
    Language: English
    Publisher: Wiley
    Publication Date: 2018
    detail.hit.zdb_id: 2014633-4
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 8
    Online Resource
    Online Resource
    Responses and feedbacks of vegetation dynamics to precipitation anomaly over the semiarid area of north China: Evidences from simulations of the WRF‐Noah model
    Wiley ; 2023
    In:  International Journal of Climatology Vol. 43, No. 2 ( 2023-02), p. 804-817
    Details
    In: International Journal of Climatology, Wiley, Vol. 43, No. 2 ( 2023-02), p. 804-817
    Abstract: Knowledge of the responses and feedbacks of vegetation dynamics to interannual climate anomalies in the semiarid area of north China is lacking. This study addresses this issue through climate modelling for 1991–2006 with the Weather Research and Forecast (WRF) model, into which a locally empirical vegetation dynamic (VED) scheme was implemented. The VED scheme was built on the basis of regression models of the leaf area index (LAI), green vegetation fraction (GVF), and surface albedo (ALB) with ambient temperature and humidity as independent variables. Using the update WRF model, the climate simulations were carried out with turning on and off VED, respectively. By comparing the simulations outputs with each other, we find that the interannual variability of precipitation from simulations with turning on VED is larger than that from simulations with turning off VED. The larger interannual variability of precipitation could be explained by VED feedback. Vegetation growth would be more vigorous, as a response, under the more precipitation, because which brings more available water. In turn, vigorous vegetation leads to more evapotranspiration and, hence, precipitable water; as a result, there would be more precipitation. It is reversed for the years with less precipitation. Such interactions between vegetation and precipitation could be summarized as positive feedback loops. This study suggests that the interannual precipitation variability can be enlarged by VED through positive evapotranspiration–precipitation feedback. It is therefore necessary to consider the vegetation dynamics for future downscaled regional climate predictions to pursue more reliable interannual climate variability.
    Type of Medium: Online Resource
    ISSN: 0899-8418 , 1097-0088
    URL: Issue
    URL: Article
    DOI: 10.1002/joc.v43.2
    DOI: 10.1002/joc.7830
    RVK:
    RA 1000
    Language: English
    Publisher: Wiley
    Publication Date: 2023
    detail.hit.zdb_id: 1491204-1
    SSG: 14
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 9
    Online Resource
    Online Resource
    Regional differences in summer monsoon precipitation variability reconstructed from multiple proxies in Asia during the past millennium
    Wiley ; 2023
    In:  International Journal of Climatology Vol. 43, No. 4 ( 2023-03-30), p. 1853-1870
    Details
    In: International Journal of Climatology, Wiley, Vol. 43, No. 4 ( 2023-03-30), p. 1853-1870
    Abstract: Rainfall in the Asia summer monsoon (ASM) domain has a complex spatial pattern with the temporal variability at different timescales and their long‐term change has not been fully characterized. An updated 320 multiple proxies network is used to reconstruct the May–October precipitation during the past millennium for eight regions in the ASM domain. The spatial consistency of summer monsoon precipitation variability and the possible links to the internal climate oscillations are investigated. The results show that the regional precipitations over the last millennium in the ASM regions are dominated by the interannual cycle of 2–2.5a and 3.5‐5a, the decadal cycle of ~11a and 15–25a and the multidecadal cycle of ~30a and 40–80a. Coherent dry decades in different regions appear in 1100–1250, 1600–1650 and 1960–2000, while the wet decades appear in 970–990, 1330–1350, 1380–1430, 1550–1580, 1700–1780 and 1810–1910. On interannual scale, the relationships between precipitation for each region and El Niño–Southern Oscillation (ENSO) in both developing and decaying stages are unstable over the entire millennium, but they have opposite‐sign correlations most of the time, which implies that the summer precipitation anomaly for a region tends to reverse in the next summer when a strong ENSO event occurs in the winter. For the long‐term change from multidecadal to centennial scales, the longest dry period of the 12th to 13th centuries in eastern Asia coincides with the period with the lowest ENSO variability due to the in phase change of the Atlantic Multidecadal Oscillation and the Pacific Decadal Oscillation, which could result in the neutral interbasin east–west cell in Tropics and low frequency of ENSO events.
    Type of Medium: Online Resource
    ISSN: 0899-8418 , 1097-0088
    URL: Issue
    URL: Article
    DOI: 10.1002/joc.v43.4
    DOI: 10.1002/joc.7949
    RVK:
    RA 1000
    Language: English
    Publisher: Wiley
    Publication Date: 2023
    detail.hit.zdb_id: 1491204-1
    SSG: 14
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 10
    Online Resource
    Online Resource
    Antigen clearance at the peak of the primary immune response induces experimental autoimmune encephalomyelitis
    Wiley ; 2023
    In:  European Journal of Immunology Vol. 53, No. 3 ( 2023-03)
    Details
    In: European Journal of Immunology, Wiley, Vol. 53, No. 3 ( 2023-03)
    Abstract: Autoimmune demyelinating diseases can be induced by an immune response against myelin peptides; however, the exact mechanism underlying the development of such diseases remains unclear. In experimental autoimmune encephalomyelitis, we found that the clearance of exogenous myelin antigen at the peak of the primary immune response is key to the pathogenesis of the disease. The generation of effector T cells requires continuous antigen stimulation, whereas redundant antigen traps and exhausts effector T cells in the periphery, which induces resistance to the disease. Moreover, insufficient antigenic stimulation fails to induce disease efficiently owing to insufficient numbers of effector T cells. When myelin antigen is entirely cleared, the number of effector T cells reaches a peak, which facilitates infiltration of more effector T cells into the central nervous system. The peripheral antigen clearance initiates the first wave of effector T cell entry into the central nervous system and induces chronic inflammation. The inflamed central nervous system recruits the second wave of effector T cells that worsen inflammation, resulting in loss of self‐tolerance. These findings provide new insights into the mechanism underlying the development of autoimmune demyelinating diseases, which may potentially impact future treatments.
    Type of Medium: Online Resource
    ISSN: 0014-2980 , 1521-4141
    URL: Issue
    URL: Article
    DOI: 10.1002/eji.v53.3
    DOI: 10.1002/eji.202250122
    RVK:
    XA 10000
    Language: English
    Publisher: Wiley
    Publication Date: 2023
    detail.hit.zdb_id: 1491907-2
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...