GLORIA

GEOMAR Library Ocean Research Information Access

X

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Online Resource
    Online Resource
    Relationship between Circulating Levels of IFN‐γ, IL‐10, CXCL9 and CCL2 in Pulmonary and Extrapulmonary Tuberculosis is Dependent on Disease Severity
    Wiley ; 2009
    In:  Scandinavian Journal of Immunology Vol. 69, No. 3 ( 2009-03), p. 259-267
    Details
    In: Scandinavian Journal of Immunology, Wiley, Vol. 69, No. 3 ( 2009-03), p. 259-267
    Abstract: Protection against Mycobacterium tuberculosis infection is dependent on T cell and macrophage activation regulated by cytokines. Cytokines and chemokines produced at disease sites may be released into circulation. Data available on circulating cytokines in tuberculosis (TB) is mostly on pulmonary TB (PTB) with limited information on extrapulmonary disease (EPul‐TB). We measured interferon‐gamma (IFN‐γ), interkeukin‐10 (IL‐10), CXCL9 and CCL2 in sera of patients ( n  = 80) including; PTB ( n  = 42), EPul‐TB ( n  = 38) and BCG vaccinated healthy endemic controls (EC, n  = 42). EPul‐TB patients comprised those with less severe (LNTB) or severe (SevTB) disease. Serum IFN‐γ, IL‐10 and CXCL9 levels were significantly greater while CCL2 was reduced in TB patients as compared with EC. IFN‐γ was significantly greater in PTB as compared with LNTB ( P  = 0.002) and SevTB ( P  = 0.029). CXCL9 was greater in PTB as compared with LNTB ( P  = 0.009). In contrast, CCL2 levels were reduced in PTB as compared with LNTB ( P  = 0.021) and SevTB ( P  = 0.024). A Spearman’s rank correlation analysis determined a positive association between IFN‐γ and IL‐10 (rho = 0.473, P  = 0.002) and IFN‐γ and CXCL9 (rho = 0.403, P  = 0.008) in the PTB group. However, in SevTB, only IFN‐γ and CXCL9 were positively associated (rho = 0.529, P  = 0.016). Systemic levels of cytokines are reflective of local responses at disease sites. Therefore, our data suggests that in PTB increased IFN‐γ and CXCL9 balanced by IL‐10 may result in a more effective cell mediated response in the host. However, elevated inflammatory chemokines CXCL9 and CCL2 in severe EPul‐TB without concomitant down modulatory cytokines may exacerbate disease related pathology and hamper restriction of M. tuberculosis infection.
    Type of Medium: Online Resource
    ISSN: 0300-9475 , 1365-3083
    URL: Issue
    URL: Article
    DOI: 10.1111/sji.2009.69.issue-3
    DOI: 10.1111/j.1365-3083.2008.02217.x
    RVK:
    XA 10000
    Language: English
    Publisher: Wiley
    Publication Date: 2009
    detail.hit.zdb_id: 2020954-X
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 2
    Online Resource
    Online Resource
    Attitudes and practices toward COVID‐19 precautionary measures: A comparative study of health professionals and public
    Wiley ; 2023
    In:  Brain and Behavior
    Details
    In: Brain and Behavior, Wiley
    Abstract: Containment of the COVID‐19 pandemic has been impaired by the denial and defiance of preventive recommendations. Aims We aimed to study the attitudes toward COVID‐19 social measures among laypersons and healthcare professionals. Methods We conducted a cross‐sectional study in the United Arab Emirates using a self‐administered online questionnaire. Both healthcare workers and laypersons were actively recruited. In addition to sociodemographic variables, the questionnaire included questions on anxiety, knowledge, and defiance related to COVID‐19. Results A total of 615 individuals with a mean age of 32 years (SD, 12) participated. Females comprised 69% and healthcare workers constituted 60% of the study sample. Among laypersons, over 42% reported having social gatherings at home, and 44% admitted to visiting crowded places. More than half of the respondents felt increased anxiety. Previous COVID‐19 infection did not affect attitudes or anxiety levels. Knowledge about COVID‐19 was higher among those who were more educated ( r  = .21). Healthcare workers had lower anxiety than laypersons ( p  = .002). COVID‐19 anxiety was higher among older persons and did not decrease with more knowledge. COVID‐19 defiance was higher among younger male respondents from larger households and did not correlate with knowledge. Multivariate analysis showed more defiant attitudes at younger ages. Conclusions Anxiety‐related to the COVID‐19 pandemic is more common in older individuals, whereas younger persons were more likely to deny and defy prevention recommendations despite having knowledge of viral transmission. Voluntary compliance by young individuals requires an engaging communication strategy to generate more compassionate attitudes.
    Type of Medium: Online Resource
    ISSN: 2162-3279 , 2162-3279
    URL: Article
    DOI: 10.1002/brb3.3267
    Language: English
    Publisher: Wiley
    Publication Date: 2023
    detail.hit.zdb_id: 2623587-0
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 3
    Online Resource
    Online Resource
    Phytochemical profile, nutritional composition of pomegranate peel and peel extract as a potential source of nutraceutical: A comprehensive review
    Wiley ; 2024
    In:  Food Science & Nutrition Vol. 12, No. 2 ( 2024-02), p. 661-674
    Details
    In: Food Science & Nutrition, Wiley, Vol. 12, No. 2 ( 2024-02), p. 661-674
    Abstract: The current study focuses on Punica granatum L. (pomegranate) peel and peel extract and their use as functional foods, food additives, or physiologically active constituents in nutraceutical formulations. The pomegranate peel extract is a good source of bioactive substances needed for the biological activity of the fruit, including phenolic acids, minerals, flavonoids (anthocyanins), and hydrolyzable tannins (gallic acid). The macromolecules found in pomegranate peel and peel extract have been recommended as substitutes for synthetic nutraceuticals, food additives, and chemo‐preventive agents because of their well‐known ethno‐medical significance and chemical properties. Moreover, considering the promises for both their health‐promoting activities and chemical properties, the dietary and nutraceutical significance of pomegranate peel and pomegranate peel extract appears to be underestimated. The present review article details their nutritional composition, phytochemical profile, food applications, nutraceutical action, and health benefits.
    Type of Medium: Online Resource
    ISSN: 2048-7177 , 2048-7177
    URL: Issue
    URL: Article
    DOI: 10.1002/fsn3.v12.2
    DOI: 10.1002/fsn3.3777
    Language: English
    Publisher: Wiley
    Publication Date: 2024
    detail.hit.zdb_id: 2703010-6
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 4
    Online Resource
    Online Resource
    Nanodiamonds: A Cutting‐Edge Approach to Enhancing Biomedical Therapies and Diagnostics in Biosensing
    Wiley ; 2024
    In:  The Chemical Record Vol. 24, No. 4 ( 2024-04)
    Details
    In: The Chemical Record, Wiley, Vol. 24, No. 4 ( 2024-04)
    Abstract: Nanodiamonds (NDs) have garnered attention in the field of nanomedicine due to their unique properties. This review offers a comprehensive overview of NDs synthesis methods, properties, and their uses in biomedical applications. Various synthesis techniques, such as detonation, high‐pressure, high‐temperature, and chemical vapor deposition, offer distinct advantages in tailoring NDs′ size, shape, and surface properties. Surface modification methods further enhance NDs′ biocompatibility and enable the attachment of bioactive molecules, expanding their applicability in biological systems. NDs serve as promising nanocarriers for drug delivery, showcasing biocompatibility and the ability to encapsulate therapeutic agents for targeted delivery. Additionally, NDs demonstrate potential in cancer treatment through hyperthermic therapy and vaccine enhancement for improved immune responses. Functionalization of NDs facilitates their utilization in biosensors for sensitive biomolecule detection, aiding in precise diagnostics and rapid detection of infectious diseases. This review underscores the multifaceted role of NDs in advancing biomedical applications. By synthesizing NDs through various methods and modifying their surfaces, researchers can tailor their properties for specific biomedical needs. The ability of NDs to serve as efficient drug delivery vehicles holds promise for targeted therapy, while their applications in hyperthermic therapy and vaccine enhancement offer innovative approaches to cancer treatment and immunization. Furthermore, the integration of NDs into biosensors enhances diagnostic capabilities, enabling rapid and sensitive detection of biomolecules and infectious diseases. Overall, the diverse functionalities of NDs underscore their potential as valuable tools in nanomedicine, paving the way for advancements in healthcare and biotechnology.
    Type of Medium: Online Resource
    ISSN: 1527-8999 , 1528-0691
    URL: Issue
    URL: Article
    DOI: 10.1002/tcr.v24.4
    DOI: 10.1002/tcr.202400006
    Language: English
    Publisher: Wiley
    Publication Date: 2024
    detail.hit.zdb_id: 2044646-9
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 5
    Online Resource
    Online Resource
    Risk profile and health vulnerability of female workers who pick cotton by organanochlorine pesticides from southern Punjab, Pakistan
    Wiley ; 2017
    In:  Environmental Toxicology and Chemistry Vol. 36, No. 5 ( 2017-05), p. 1193-1201
    Details
    In: Environmental Toxicology and Chemistry, Wiley, Vol. 36, No. 5 ( 2017-05), p. 1193-1201
    Abstract: The present study was conducted to highlight the existing level of organochlorine‐pesticides (OCPs) from human milk ( n  = 45) and blood serum ( n  = 40) of female workers who pick cotton in Khanewal District, southern Punjab, Pakistan. Source apportionment, congener‐specific analysis, and risk surveillance of OCPs are reported from human milk and blood samples. Levels of OCPs in milk and blood serum samples ranged from 15.7 ppb to 538.3 ppb and from 16.4 ppb to 747.1 ppb, respectively, and were lower than previously published reports from other regions of the globe. Congener‐specific analysis revealed that DDTs were predominant, followed by hexachlorocyclohexane, chlordane, and hexachlorobenzene. Calculated results for source apportionment analysis suggested that contamination load was a new input of DDTs as well as the historic use of lindane in the study area. Levels of OCPs in milk and blood serum were significantly ( p   〈  0.05) correlated with age, time period of picking cotton, and number of children. Health risk revealed that female workers had risk of cancer among 1 per million; however, noncarcinogenic risks were not considerable. Environ Toxicol Chem 2017;36:1193–1201. © 2016 SETAC
    Type of Medium: Online Resource
    ISSN: 0730-7268 , 1552-8618
    URL: Issue
    URL: Article
    DOI: 10.1002/etc.v36.5
    DOI: 10.1002/etc.3633
    Language: English
    Publisher: Wiley
    Publication Date: 2017
    detail.hit.zdb_id: 2027441-5
    SSG: 12
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 6
    Online Resource
    Online Resource
    Economic evaluation of bariatric surgery to combat morbid obesity: A study from the W est of S cotland
    Wiley ; 2013
    In:  Asian Journal of Endoscopic Surgery Vol. 6, No. 3 ( 2013-08), p. 197-202
    Details
    In: Asian Journal of Endoscopic Surgery, Wiley, Vol. 6, No. 3 ( 2013-08), p. 197-202
    Abstract: The increasing prevalence of obesity has now become a global concern. Forecasts of its health and financial ramifications have prompted the need for effective interventions. Bariatric surgery is an effective measure to control obesity and its related comorbidities, but its high upfront costs have raised questions about its cost‐effectiveness. In this study we evaluated the health care‐related direct cost savings after bariatric surgery. Methods Data were prospectively obtained from patients who underwent bariatric surgery between M ay 2008 and A pril 2011, and a review was performed. These patients' annual cost of regular medications, hospital admissions and outpatient clinic visits were compared with the postoperative costs of these services. Data were collected from J anuary 2005 to A pril 2012. Results The analysis included 88 patients, 17 of whom were men and 71 were women. The procedures included 36 laparoscopic adjustable gastric banding, 33 sleeve gastrectomies and 19 R oux‐en‐ Y gastric bypasses. All procedures were laparoscopic. Data were collected from patients during a median preoperative period of 60 months (range, 42–75 months) and a median postoperative period of 24 months (range, 12–45 moths). Annual savings were £11 452 on medications, £16 420 on hospital admissions and £2532 on outpatient clinic visits. Total annual savings were £30 404. Conclusion Given the rising prevalence of morbid obesity, bariatric surgery is a cost‐effective treatment for morbid obesity and should be made available to morbidly obese patients.
    Type of Medium: Online Resource
    ISSN: 1758-5902 , 1758-5910
    URL: Issue
    URL: Article
    DOI: 10.1111/ases.2013.6.issue-3
    DOI: 10.1111/ases.12042
    Language: English
    Publisher: Wiley
    Publication Date: 2013
    detail.hit.zdb_id: 2492135-X
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 7
    Online Resource
    Online Resource
    Improving the Recombination Losses by the Inclusion of Bi‐HTM (CuO/Silicon) Layers for Formamidinium Tin‐Based Perovskite Solar Cells
    Wiley ; 2023
    In:  Advanced Theory and Simulations Vol. 6, No. 8 ( 2023-08)
    Details
    In: Advanced Theory and Simulations, Wiley, Vol. 6, No. 8 ( 2023-08)
    Abstract: The innovative lead‐free formamidinium tin‐based perovskite solar cell structure is considered nontoxic and potentially more stable than lead‐based, although its performance is not yet excellent. This research aims to enhance the power conversion efficiency of perovskite solar cells and reduce the recombination losses. According to device modeling, the FASnI 3 perovskite solar cell demonstrates a packing conversion efficiency of 14.3% (open circuit voltage ( V oc ) = 0.899 V, fill factor (FF) = 58.9%, and current density ( J sc ) = 26.06 mA cm −2 ) by employing Bi hole transporting layers, a copper oxide, and crystalline silicon layers. Some features that affect the device include the thickness of each layer, the doping density of copper oxide and a silicon layer, and the back contact metalwork function. It is proposed that Bi‐HTL reduce the carriers to enter hole transport layer (HTL) as the doping change so that decreasing charge carriers recombination and enhancing the device efficiency in tin‐based perovskite solar cell with the structure of ITO/TiO 2 /FASnI 3 /CuO/Si/C. Furthermore, the impacts of various charge transport layers on energy band alignment, recombination, electric field, and IV properties are thoroughly explored.
    Type of Medium: Online Resource
    ISSN: 2513-0390 , 2513-0390
    URL: Issue
    URL: Article
    DOI: 10.1002/adts.v6.8
    DOI: 10.1002/adts.202300106
    Language: English
    Publisher: Wiley
    Publication Date: 2023
    detail.hit.zdb_id: 2894557-8
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 8
    Online Resource
    Online Resource
    On the calibration and applicability of global solar radiation models based on temperature extremities in India
    Wiley ; 2020
    In:  Environmental Progress & Sustainable Energy Vol. 39, No. 1 ( 2020-01)
    Details
    In: Environmental Progress & Sustainable Energy, Wiley, Vol. 39, No. 1 ( 2020-01)
    Abstract: In the present work, global solar radiation models based on the difference of monthly‐average daily ambient temperature extremes are calibrated for country‐wide application in India. Solar radiation measurements obtained from the Indian Meteorological Department for 22 locations of India for a duration of 15 years (1986–2000) were used. Solar radiation models based on temperature extremes were reviewed and 33 forms were considered for analysis. The models were derived using all the collected data by fitting a model form and extracting the coefficients with the help of DataFit® software. The calibrated models were analyzed and compared using statistical tools and ranked using Global Performance Indicator (GPI) where a higher value represented a model's better performance. Then, the models were arranged using GPI and it was found that model form 33 (fourth order polynomial) resulted in best estimation capability with a GPI of 0.0763. Further, Model 23, Model 28, Model 24, and Model 26 were also among the top models with GPI values of 0.0655, 0.0587, 0.0478, and 0.0426, respectively. Best ranking models were also used to obtain estimates for representative sites in regions with different climate characteristics within India and it was found that the models performed reasonably well.
    Type of Medium: Online Resource
    ISSN: 1944-7442 , 1944-7450
    URL: Issue
    URL: Article
    DOI: 10.1002/ep.v39.1
    DOI: 10.1002/ep.13236
    Language: English
    Publisher: Wiley
    Publication Date: 2020
    detail.hit.zdb_id: 2462324-6
    SSG: 21
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 9
    Online Resource
    Online Resource
    Biomass derived Fibers as a Substitute to Synthetic Fibers in Polymer Composites
    Wiley ; 2020
    In:  ChemBioEng Reviews Vol. 7, No. 6 ( 2020-12), p. 193-215
    Details
    In: ChemBioEng Reviews, Wiley, Vol. 7, No. 6 ( 2020-12), p. 193-215
    Abstract: Advancement in science and technology provides the significant opportunities to utilize the plant fibers (unnoticed materials), which are cheap, abundant, sustainable, and biodegradable. A combination of polymer with the untreated and treated fibers, extracted from lignocellulosic biomass, has been getting significant attention because of their low cost, ecofriendly nature, and enhanced mechanical performance. This article delivers an explicit overview of the plant fibers, extraction and pretreatment of the plant fibers, development of the plant fibers reinforced polymeric composites, and the mechanical properties associated with these biocomposites. A special focus is concentrated on the pretreatment of hydrophilic plant fibers for better compatibility with the polymers, to obtain the enhanced composites having desirable properties. Finally, the effects of several pretreatments on the tensile and water absorption properties of the plant fibers reinforced composites has been included in detail for the better understanding of their practical applications.
    Type of Medium: Online Resource
    ISSN: 2196-9744 , 2196-9744
    URL: Issue
    URL: Article
    DOI: 10.1002/cben.v7.6
    DOI: 10.1002/cben.202000002
    Language: English
    Publisher: Wiley
    Publication Date: 2020
    detail.hit.zdb_id: 2754405-9
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 10
    Online Resource
    Online Resource
    An empirical examination of SMEs sustainable performance through lean manufacturing
    Wiley ; 2023
    In:  Knowledge and Process Management Vol. 30, No. 3 ( 2023-07), p. 289-299
    Details
    In: Knowledge and Process Management, Wiley, Vol. 30, No. 3 ( 2023-07), p. 289-299
    Abstract: In the modern business world, manufacturing entities seek the modern way of production, which can help them to minimize the wastage of material. To minimize the wastage of materials in manufacturing entities, use different modern techniques, and one of the modern techniques is lean manufacturing. This study aims to explore the relationship between lean manufacturing and the sustainable performance (SP) of the firm. For this purpose, data were collected from SMEs working in Pakistan. Results elaborate that four lean manufacturing practices, that is, process and equipment, product design, supplier relationship, and customer relationship have a positive and significant impact on SP, but the impact of planning and control and HR practices could not be verified. Moreover, green supply chain management (GSCM) found a mediator between HR practices, product design, supplier relationships, customer relationships, and SP. Outcomes of this study provide the higher management of SMEs with a way forward to implement modern techniques within their organizations to minimize the wastage of material during the manufacturing process. Furthermore, this study will cover the deficiency in the literature about the mediating role of GSCM between lean manufacturing and sustainable performance.
    Type of Medium: Online Resource
    ISSN: 1092-4604 , 1099-1441
    URL: Issue
    URL: Article
    DOI: 10.1002/kpm.v30.3
    DOI: 10.1002/kpm.1740
    Language: English
    Publisher: Wiley
    Publication Date: 2023
    detail.hit.zdb_id: 2021210-0
    SSG: 3,2
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...