In:
ANZ Journal of Surgery, Wiley, Vol. 86, No. 4 ( 2016-04), p. 294-298
Abstract:
To investigate the impact of operation timing on post‐operative infections in a cohort of patients undergoing colorectal cancer surgery. Methods We prospectively analysed surgical outcomes in patients who underwent colorectal cancer surgery at the F irst A ffiliated H ospital, C ollege of M edicine, Z hejiang U niversity, from J anuary to D ecember in 2014. In this non‐randomized trial, patients were divided into three groups according to the surgery start time: CT 1 (07:00 to 12:00 h), CT 2 (12:01 to 18:00 h), and CT 3 (18:01 h to midnight). The primary outcome was the proportion of patients developing infections within 4 weeks of the surgical procedure. Results Out of 756 patients that were enrolled in the study, 118 developed post‐operative infections. The results from blood and pus culture showed 97.1% specimen as being pathogen‐free. The overall incidence of post‐operative infection was 14.5% (38 of 262), 15.3% (46 of 300) and 17.5% (34 of 194) in the CT 1, CT 2 and CT 3 group, respectively, with no significant inter‐group differences. However, white blood cell counts, C ‐reactive protein and glucose levels at 24 h after the surgical procedure showed significant differences between the three groups (one‐way ANOVA , P 〈 0.05). Conclusion The occurrence of post‐operative infection in patients undergoing colorectal cancer surgery was not associated with operation timing. The expression of several inflammatory markers, such as white blood cell counts, C ‐reactive protein and blood glucose levels tended to correlate with the surgery start time.
Type of Medium:
Online Resource
ISSN:
1445-1433
,
1445-2197
DOI:
10.1111/ans.2016.86.issue-4
Language:
English
Publisher:
Wiley
Publication Date:
2016
detail.hit.zdb_id:
2095927-8
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