In:
Journal of Veterinary Internal Medicine, Wiley, Vol. 28, No. 3 ( 2014-05), p. 847-856
Abstract:
Diet might influence progression of hypertrophic cardiomyopathy ( HCM ). Objective To investigate whether diet composition could alter clinical, biochemical, or echocardiographic variables in cats with HCM . Animals Twenty‐nine cats with HCM (International Small Animal Cardiac Health Council stage 1b) examined at a university teaching hospital. Methods Randomized, placebo‐controlled trial. After physical examination, echocardiogram, and blood collection, cats were randomized to 1 of 3 diets, which varied in carbohydrate and fat content and ingredients. Measurements were repeated after 6 months. Results There were no significant differences among the 3 groups at baseline. After 6 months, there were no significant changes in the primary endpoints, left ventricular free wall (Group A, P = .760; Group B, P = .475; Group C, P = .066) or interventricular septal thickness in diastole (Group A, P = .528; Group B, P = .221; Group C, P = .097). Group A had significant increases in BUN ( P = .008) and cholesterol ( P = .021), while Group B had significant increases in BUN ( P = .008), cholesterol ( P = .007), and triglycerides ( P = .005), and significant decreases in NT ‐pro BNP ( P = .013) and hs‐troponin I ( P = .043). Group C had significant decreases in body weight ( P = .021), left atrial dimension ( P = .035), interventricular septal thickness in systole ( P = .038), and liver enzymes ( P = .034–.038). Conclusions and Clinical Importance These data suggest that diet might influence some clinical, biochemical, and echocardiographic variables in cats with HCM .
Type of Medium:
Online Resource
ISSN:
0891-6640
,
1939-1676
DOI:
10.1111/jvim.2014.28.issue-3
Language:
English
Publisher:
Wiley
Publication Date:
2014
detail.hit.zdb_id:
2177690-8
SSG:
22
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