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  • 1
    In: Ultrasound in Obstetrics & Gynecology, Wiley, Vol. 18, No. s1 ( 2001-10)
    Abstract: A prospective cross‐sectional study was developed to determine the correlation between the umbilical cord cross‐sectional (UCCSA) and fetal anthropometric parameters during normal pregnancies (patients with known dates of LMP and an ultrasound examination before the 20th week, without any pathologic condition). The measurements of the umbilical cord cross‐sectional area were obtained in a plane adjacent to the insertion of the cord in the abdomen, as proposed by Raio et al. , 1999, and compared to the biparietal diameter (BPD), head circumference (HC), abdominal circumference (AC) and femur length (FL) by the non‐parametric correlation of Spearman. The inclusion criteria were: (1) singleton pregnancy; (2) gestational week 〉 20 weeks; (3) intact membranes; (4) normal umbilical Doppler flow velocimetry. The exclusion criteria, in the presence of any of those were: (1) congenital and/or chromosomal abnormalities; (2) pregnancy complications (any type); (3) inadequate size for gestational agent the time the ultrasound examination was performed, i.e. the weight below the 10th or above the 90th percentile; (4) abnormal AFI. The patients were examined and included only once. The statistical analysis was performed by the program called Statistical Package for Social Sciences (SPSS) and we used a Toshiba 140 with a transabdominal transducer of 3.5 MHz. Our results showed a strong correlation (Spearman rank = 0.610, significant at the level of P   〈  0.01) between the UCCSA and the estimated fetal weight by ultrasound examination and also with the fetal anthropometric parameters (UCCSA × BPD = 0.622; UCCSA × HC = 0.617; UCCSA × AC = 0.625; UCCSA × FL = 0.604, all of them significant at the level of P   〈  0.01). We concluded that the UCCSA is a parameter that can be included at the routine of obstetrical ultrasound examinations.
    Type of Medium: Online Resource
    ISSN: 0960-7692 , 1469-0705
    Language: English
    Publisher: Wiley
    Publication Date: 2001
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  • 2
    In: Ultrasound in Obstetrics & Gynecology, Wiley, Vol. 18, No. s1 ( 2001-10)
    Abstract: A prospective cross‐sectional study was developed in order to determine reference ranges for the umbilical cord cross‐sectional area (UCCSA) during normal pregnancies (patients with known dates of LMP and an ultrasound examination before the 20th week, without any pathologic condition). The measurements of the UCCSA were obtained in a plane adjacent to the insertion of the cord abdomen, as proposed by Raio et al , 1999. The inclusion criteria were: (1) singleton pregnancy, (2) gestation age 〉 20 weeks, (3) intact membranes, (4) normal umbilical Doppler flow velocimetry. The exclusion criteria, in the presence of any of those, were: (1) congenital and/or chromosomal abnormalities; (2) pregnancy complications (any type); (3) inadequate size for gestational age when the examination was performed, i.e. the weight below the 10th percentile or above the 90th; (4) abnormal AFI for the gestational age. The patients were examined and included only once. During the period of the study (February 2000–May 2001), 545 patients were examined, after meeting the inclusion criteria determined for the present study. The age of the patients ranged from 15 to 42 years (mean = 26.7 ± 4.8), 242 patients (44.4%) had two gestations, 135 patients (28.1%) were at their first gestation, 129 patients (23.7%) were at their third gestation and 39 patients had four or more gestations (3.8%). The ultrasound machine used was the Synergy Multi Sync M 500 and the statistical analysis was performed by the program called Statistical Package for Social Sciences (SPSS). Our data were considered normally by the Kolmogorov–Smirnov test and then we figured the nomogram by linear regression analysis. The analysis of variance obtained through the F ‐test (value = 356.27) showed that our regression model was significant at the level of P   〈  0.001, showing that the curve represented well the studied population and that the confidence interval (95%) contained the real value of the UCCSA. The regression equation was: y  = − 532.27 + 44.358 x  − 0.6555 x 2 . We conclude that, there is a progressive increase in the UCCSA up to the 32nd week of gestation, followed by a stabilization until the 34th week and a fall of the values from the 35th week of gestation.
    Type of Medium: Online Resource
    ISSN: 0960-7692 , 1469-0705
    Language: English
    Publisher: Wiley
    Publication Date: 2001
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  • 3
    In: Ultrasound in Obstetrics & Gynecology, Wiley, Vol. 18, No. s1 ( 2001-10)
    Abstract: A prospective cross‐sectional study was developed in order to determine the reproducibility of the measurement of the umbilical cord cross‐sectional area (UCCSA) during normal pregnancies (patients with known dates of LMP and an ultrasound examination before the 20th week, without any pathologic condition), measured by different and trained examiners. The measurements of the umbilical cord cross‐sectional area were obtained in a plane adjacent to the insertion of the cord abdomen, as proposed by Raio et al. 1999, after the different examiners were trained by the author. The inclusion criteria were: (1) singleton pregnancy; (2) gestation age 〉 20 weeks; (3) intact membranes (4) normal umbilical Doppler flow velocimetry. The exclusion criteria, in the presence of any of those were: (1) congenital and/or chromosomal abnormalities; (2) pregnancy complications (any type); (3) inadequate size for gestational age with when the examination was performed, i.e. the weight below the 10th percentile or above the 90th; (4) abnormal AFI for the gestational age. The patients were examined and included only once. During the period of the study (February 2000–May 2001), 545 patients were examined, after meeting the inclusion criteria determined for the present study. The age of the patients ranged from 15 to 42 years (mean = 26.7 ± 4.8), 242 patients (44.4%) had two gestations, 135 patients (28.1%) were at their first gestation, 129 patients (23.7%) were at their third gestation and 39 patients had four or more gestations (3.8%). The ultrasound machine used was the Synergy Multi Sync M 500. The statistical program used was the statistical package for social sciences (SPSS). The first examiner collected 22% of the data, the second examiner collected 45% of the data, the third examiner collected 24% of the data and the fourth one collected 9% of the data. According to the analysis of variance ( anova ), we performed, comparing the data obtained by the different examiners, no significance was found and this fact was also showed by the comparison of the data among them and verifying that the data had a dispersion inside tolerable limits. The anova showed the following data (example for 3 weeks): At 25 weeks, the F ‐test showed a value of 0.930 and a P ‐value of 0.454; at 32 weeks the values were 0.106 for the F ‐test and 0.956 for the P ‐value and for week 38 the values were 0.102 ( F ‐test) and 0.904 ( P ‐value). We conclude that the measurement of the UCCSA as proposed by Raio et al. 1999 is reproductible and can be adopted as a new obstetric ultrasound parameter.
    Type of Medium: Online Resource
    ISSN: 0960-7692 , 1469-0705
    Language: English
    Publisher: Wiley
    Publication Date: 2001
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  • 4
    In: Journal of Cellular Physiology, Wiley, Vol. 198, No. 3 ( 2004-03), p. 479-480
    Abstract: The original article to which this Erratum was published in J. Cell. Physiol. 198:324–332, 2004 It has been recently established that low‐frequency electromagnetic field (EMFs) exposure induces biological changes and could be associated with increased incidence of cancer, while the issue remains unresolved as to whether high‐frequency EMFs can have hazardous effect on health. Epidemiological studies on association between childhood cancers, particularly leukemia and brain cancer, and exposure to low‐ and high‐frequency EMF suggested an etiological role of EMFs in inducing adverse health effects. To investigate whether exposure to high‐frequency EMFs could affect in vitro cell survival, we cultured acute T‐lymphoblastoid leukemia cells (CCRF‐CEM) in the presence of unmodulated 900 MHz EMF, generated by a transverse electromagnetic (TEM) cell, at various exposure times. We evaluated the effects of high‐frequency EMF on cell growth rate and apoptosis induction, by cell viability (MTT) test, FACS analysis and DNA ladder, and we investigated pro‐apoptotic and pro‐survival signaling pathways possibly involved as a function of exposure time by Western blot analysis. At short exposure times (2–12 h), unmodulated 900 MHz EMF induced DNA breaks and early activation of both p53‐dependent and ‐independent apoptotic pathways while longer continuous exposure (24–48 h) determined silencing of pro‐apoptotic signals and activation of genes involved in both intracellular (Bcl‐2) and extracellular (Ras and Akt1) pro‐survival signaling. Overall our results indicate that exposure to 900 MHz continuous wave, after inducing an early self‐defense response triggered by DNA damage, could confer to the survivor CCRF‐CEM cells a further advantage to survive and proliferate. J. Cell. Physiol. 198: 324–332, 2004. © 2003 Wiley‐Liss, Inc.
    Type of Medium: Online Resource
    ISSN: 0021-9541 , 1097-4652
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2004
    detail.hit.zdb_id: 1478143-8
    SSG: 12
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  • 5
    In: European Journal of Immunology, Wiley, Vol. 26, No. 1 ( 1996-01), p. 17-27
    Type of Medium: Online Resource
    ISSN: 0014-2980 , 1521-4141
    URL: Issue
    RVK:
    Language: English
    Publisher: Wiley
    Publication Date: 1996
    detail.hit.zdb_id: 1491907-2
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  • 6
    Online Resource
    Online Resource
    Wiley ; 2015
    In:  Nations and Nationalism Vol. 21, No. 3 ( 2015-07), p. 445-460
    In: Nations and Nationalism, Wiley, Vol. 21, No. 3 ( 2015-07), p. 445-460
    Abstract: Historiography on the phenomenology of nationalisms has often pointed to the importance of myths and symbols in the construction of these political movements, underlining how the past is transfigured and/or particular historical episodes are recast for use in creating a given political discourse in the present. By adopting this viewpoint, the aim of this paper is to analyse the evolution of historiographical thinking on the use of myths and symbols in contemporary politics, giving particular attention to how they were brought to bear in the early days of the C atalan nationalist movement. This initial period, covering the late nineteenth and early twentieth centuries, is of special interest in the case of C atalan nationalism because it was a phase of politicisation marked – much as it was in other nationalist movements across E urope – by a nationalisation of history, a selection of foundation myths and historical milestones, and a crystallisation of the movement's symbols.
    Type of Medium: Online Resource
    ISSN: 1354-5078 , 1469-8129
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2015
    detail.hit.zdb_id: 1500007-2
    SSG: 3,6
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  • 7
    In: Haemophilia, Wiley, Vol. 22, No. 6 ( 2016-11), p. 949-956
    Abstract: The heterogeneity of von Willebrand disease ( VWD ) makes its diagnosis a difficult task. Methods We report here on the usefulness of a microchip‐based flow‐chamber system, the total thrombus‐formation analysis system (T‐ TAS ), in the identification and characterization of VWD . Thirty VWD patients and 20 healthy subjects were studied with the T‐ TAS platelet ( PL ) and atherome ( AR ) microchips developed for the in vitro assessment of platelet thrombus formation and fibrin‐rich platelet thrombus formation respectively. Results Samples from severe type 1 VWD , characterized by von Willebrand factor ( VWF ) levels below 10 U dL −1 , failed to occlude either the PL or the AR chip capillaries, while the occlusion times were normal in patients with mild type 1 VWD ( VWF above 25 U dL −1 ). PL and/or AR chip occlusion occurred, but took longer than normal, for samples from type Vicenza and type 1 VWD patients, whose VWF levels ranged between 10 and 25 U dL −1 . No PL or AR chip capillary occlusion was seen for samples from patients with type 2A or 2B VWD featuring the absence of large VWF multimers, whereas no abnormalities emerged for type 2B patients with normal multimer patterns. Conclusion The T‐ TAS appears to be sensitive mainly to plasma VWF concentration and the presence of large multimers. Failure of the PL and AR chips to become occluded points to a lack of large VWF multimers, or type 1 VWD with VWF levels below 10 U dL −1 . Although the T‐ TAS does not assure a precise VWD diagnosis, it does point us in the right direction, and thus seems a useful global preliminary test.
    Type of Medium: Online Resource
    ISSN: 1351-8216 , 1365-2516
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2016
    detail.hit.zdb_id: 2006344-1
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  • 8
    In: Journal of Cellular Physiology, Wiley, Vol. 198, No. 2 ( 2004-02), p. 324-332
    Abstract: An Erratum has been published for this article in Journal of Cellular Physiology 198: 479–480, 2004 . It has been recently established that low‐frequency electromagnetic field (EMFs) exposure induces biological changes and could be associated with increased incidence of cancer, while the issue remains unresolved as to whether high‐frequency EMFs can have hazardous effect on health. Epidemiological studies on association between childhood cancers, particularly leukemia and brain cancer, and exposure to low‐ and high‐frequency EMF suggested an etiological role of EMFs in inducing adverse health effects. To investigate whether exposure to high‐frequency EMFs could affect in vitro cell survival, we cultured acute T‐lymphoblastoid leukemia cells (CCRF‐CEM) in the presence of unmodulated 900 MHz EMF, generated by a transverse electromagnetic (TEM) cell, at various exposure times. We evaluated the effects of high‐frequency EMF on cell growth rate and apoptosis induction, by cell viability (MTT) test, FACS analysis and DNA ladder, and we investigated pro‐apoptotic and pro‐survival signaling pathways possibly involved as a function of exposure time by Western blot analysis. At short exposure times (2–12 h), unmodulated 900 MHz EMF induced DNA breaks and early activation of both p53‐dependent and ‐independent apoptotic pathways while longer continuous exposure (24–48 h) determined silencing of pro‐apoptotic signals and activation of genes involved in both intracellular (Bcl‐2) and extracellular (Ras and Akt1) pro‐survival signaling. Overall our results indicate that exposure to 900 MHz continuous wave, after inducing an early self‐defense response triggered by DNA damage, could confer to the survivor CCRF‐CEM cells a further advantage to survive and proliferate. J. Cell. Physiol. 198: 324–332, 2004© 2003 Wiley‐Liss, Inc.
    Type of Medium: Online Resource
    ISSN: 0021-9541 , 1097-4652
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2004
    detail.hit.zdb_id: 1478143-8
    SSG: 12
    Location Call Number Limitation Availability
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