In:
Clinical Transplantation, Wiley, Vol. 30, No. 7 ( 2016-07), p. 828-835
Abstract:
Kidney transplant ( KT ) programs have extended recipient eligibility to those who were previously excluded due to advanced age. We aimed to determine the outcomes of the patients ≥70 years undergoing KT and investigate factors predicting survival. Two thousand six hundred and twenty‐four KT patients between 2003 and 2013 at two institutions were divided into two groups; those ≥70 years (n=300) and those 〈 70 years (n=2324) at the time of KT . Patient survival at 1, 3, and 5 years was 95%, 86%, and 77% in ≥70 years of age group and 98%, 95%, and 90% in the 〈 70 years group ( P 〈 .001). When graft loss due to death was censored, graft survival was not significantly different between the two groups ( P =.18). On multivariable analysis, the significant predictors of inferior survival in patients ≥70 years included: body mass index ( BMI ) 〉 30 kg/m 2 (hazard ratio [ HR ] 1.07; P =.01), panel reactive antibody ( PRA ) 〉 20% ( HR 2.38; P =.01), previous coronary artery bypass grafting ( CABG ; HR 1.95; P =.03) and peripheral vascular disease ( PVD ; HR 2.60; P =.04). Acceptable outcomes can be achieved in KT recipients ≥70 years. Caution should be used when listing these patients if they have BMI 〉 30 kg/m 2 , PRA 〉 20%, CABG or PVD .
Type of Medium:
Online Resource
ISSN:
0902-0063
,
1399-0012
DOI:
10.1111/ctr.2016.30.issue-7
Language:
English
Publisher:
Wiley
Publication Date:
2016
detail.hit.zdb_id:
2739458-X
detail.hit.zdb_id:
2004801-4
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