In:
Diabetes, Obesity and Metabolism, Wiley, Vol. 19, No. 7 ( 2017-07), p. 1051-1055
Abstract:
Continuous and flash glucose monitoring ( GM ) systems have been established in diabetes care. We compared the sensor performance of 3 commercially available GM systems. A total of 12 patients with type 1 diabetes were included in a single‐centre, open‐label study in which the sensor performance of the A bbott FreeStyle libre ( A bbott), D excom G4 P latinum ( D excom) and M edtronic MiniMed 640G ( M edtronic) systems over 12 hours was compared during mimicked real‐life conditions (meals, exercise, hypo‐ and hyperglycaemia). Sensor performance was determined by fulfilment of ISO 15197:2013 criteria, calculating mean absolute relative difference ( MARD ), and was also illustrated using P arkes error grid and B land– A ltman plots. Sensor performance during changes in metabolic variables (lactate, betahydroxybutyrate, glucagon, non‐esterified‐fatty‐acids) was determined by S pearman's rank correlation coefficient testing. The systems fulfilled ISO 15197:2013 criteria by 73.2% ( A bbott), 56.1% ( D excom) and 52.0% ( M edtronic). The MARDs ± standard deviation in the entire glycaemic range were 13.2% ± 10.9% ( A bbott), 16.8% ± 12.3% ( D excom) and 21.4% ± 17.6% ( M edtronic), respectively. All sensors performed less accurately during hypoglycaemia and best during hyperglycaemia. We did not observe an influence of metabolic variables on sensor performance.
Type of Medium:
Online Resource
ISSN:
1462-8902
,
1463-1326
DOI:
10.1111/dom.2017.19.issue-7
Language:
English
Publisher:
Wiley
Publication Date:
2017
detail.hit.zdb_id:
2004918-3
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