In:
Journal of Clinical Periodontology, Wiley, Vol. 45, No. 3 ( 2018-03), p. 354-363
Abstract:
This study assessed the impact of anti‐infective periodontal therapy on the status of vascular health. Materials and Methods Periodontal and vascular health of 55 patients with severe untreated chronic periodontitis was evaluated before and 12 months after anti‐infective periodontal therapy. Observed parameters were bleeding on probing (BoP), pocket probing depth ( PPD ), periodontal inflamed surface area index ( PISA ), pulse wave velocity ( PWV ), augmentation index ( AI x), central pulse pressure ( PP ao) and peripheral systolic pressure ( RR sys). Results Δ PISA (baseline‐12 months) correlated with Δ PWV (τ 0.21; p 〈 .03), Δ AI x (τ 0.29; p 〈 .002) and Δ PP ao (τ 0.23; p 〈 .02). ΔBoP% (baseline‐12 months) correlated with Δ PWV (τ 0.18; p 〈 .05) and Δ AI x (τ 0.25; p 〈 .01), while mean Δ PPD (baseline‐12 months) correlated with Δ PWV (τ 0.24; p 〈 .01) and Δ AI x (τ 0.21; p 〈 .03). Grouping patients evenly into three groups based on tertiles of BoP resolution after 12 months revealed a significant decrease in the observed PWV median value by −0.6 m/s ( p 〈 .04) in the best response tertile (ΔBoP ≥ 88%). In the worst response tertile (ΔBoP ≤ 66%), by contrast, significant increase in PP ao (+10.5 mmHg; p 〈 .02) and AI x (+5.5; p 〈 .02) was observed. Conclusion Efficacious resolution of periodontal inflammation may beneficially impact on vascular health.
Type of Medium:
Online Resource
ISSN:
0303-6979
,
1600-051X
DOI:
10.1111/jcpe.2018.45.issue-3
Language:
English
Publisher:
Wiley
Publication Date:
2018
detail.hit.zdb_id:
2026349-1
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