In:
International Journal of Cancer, Wiley, Vol. 141, No. 4 ( 2017-08-15), p. 711-720
Abstract:
What's new? Aflatoxin B 1 (AFB 1 ), a potent carcinogen produced by fungi, is the most abundant aflatoxin found in contaminated food. Here, the authors examined its association with liver cirrhosis risk. Using an ELISA to measure AFB 1 ‐albumin adducts in the blood, they found that AFB 1 exposure increases the risk of developing cirrhosis and liver cancer, and may also accelerate the progression of chronic hepatitis B virus infection to both conditions. They conclude that AFB 1 may not only contribute to hepatocarcinogenesis directly, but also indirectly by rendering liver cells more vulnerable by promoting cirrhosis.
Type of Medium:
Online Resource
ISSN:
0020-7136
,
1097-0215
Language:
English
Publisher:
Wiley
Publication Date:
2017
detail.hit.zdb_id:
218257-9
detail.hit.zdb_id:
1474822-8
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