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  • Walter de Gruyter GmbH  (8)
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  • Walter de Gruyter GmbH  (8)
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  • 1
    Online Resource
    Online Resource
    Effect of diffusion on interfacial properties of polyurethane-modified asphalt–aggregate using molecular dynamic simulation
    Walter de Gruyter GmbH ; 2022
    In:  REVIEWS ON ADVANCED MATERIALS SCIENCE Vol. 61, No. 1 ( 2022-10-28), p. 778-794
    Details
    In: REVIEWS ON ADVANCED MATERIALS SCIENCE, Walter de Gruyter GmbH, Vol. 61, No. 1 ( 2022-10-28), p. 778-794
    Abstract: In order to understand the diffusion behavior of polyurethane (PU) in asphalt and the adhesion between modified asphalt and aggregate, the diffusion system of PU-modified asphalt was studied by molecular dynamics simulation software. Asphalt molecular model, PU molecular model, and PU-modified asphalt molecular model were established, respectively, and were geometrically optimized. The interface model between original asphalt molecule and aggregate, modified asphalt molecule and aggregate, PU molecule and asphalt molecule are established. The diffusion coefficient is calculated from the mean square displacement curve of asphalt and PU, so as to characterize the diffusion ability of asphalt and PU. The adhesion between modified asphalt and aggregate is characterized the interface energy between modified asphalt and aggregate. The results show that the molecular movement of the two substances is relatively active, and the micro-holes in the system structure can be filled in a short time. The interface energy between PU-modified asphalt and aggregate is more significant than that between original asphalt and aggregate. PU-modified asphalt has good diffusion ability and better adhesion with aggregate.
    Type of Medium: Online Resource
    ISSN: 1605-8127
    URL: Article
    DOI: 10.1515/rams-2022-0265
    Language: English
    Publisher: Walter de Gruyter GmbH
    Publication Date: 2022
    detail.hit.zdb_id: 2033066-2
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  • 2
    Online Resource
    Online Resource
    Deterministic Deployment for Directional Sensor Nodes
    Walter de Gruyter GmbH ; 2016
    In:  International Journal on Smart Sensing and Intelligent Systems Vol. 9, No. 4 ( 2016-01-01), p. 2032-2050
    Details
    In: International Journal on Smart Sensing and Intelligent Systems, Walter de Gruyter GmbH, Vol. 9, No. 4 ( 2016-01-01), p. 2032-2050
    Abstract: Node deployment is the key problem of wireless sensor network technology in application. The existing study on deployment of deterministic perceived nodes is simplified to the randomly deployment. In this paper, we take the effective coverage, connectivity and probability threshold as the evaluation indices to analyze the different deployment models. Experimental results demonstrate that the effective coverage area of the triangle deployment is the largest when using the same number of nodes; and if the probability is less than limits, tile deployment does not need to increase the node to ensure coverage. The research results of this paper provide an important reference for the deployment of the directional sensor networks with the given parameters.
    Type of Medium: Online Resource
    ISSN: 1178-5608
    URL: Article
    DOI: 10.21307/ijssis-2017-951
    Language: English
    Publisher: Walter de Gruyter GmbH
    Publication Date: 2016
    detail.hit.zdb_id: 2519374-0
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  • 3
    Online Resource
    Online Resource
    Multiple nontrivial solutions of superlinear fractional Laplace equations without (AR) condition
    Walter de Gruyter GmbH ; 2023
    In:  Advances in Nonlinear Analysis Vol. 12, No. 1 ( 2023-02-18)
    Details
    In: Advances in Nonlinear Analysis, Walter de Gruyter GmbH, Vol. 12, No. 1 ( 2023-02-18)
    Abstract: In this article, we study a class of nonlinear fractional Laplace problems with a parameter and superlinear nonlinearity ( − Δ ) s u = λ u + f ( x , u ) , in Ω , u = 0 , in R N \ Ω . \left\{\phantom{\rule[-1.25em]{}{0ex}}\begin{array}{ll}{\left(-\Delta )}^{s}u=\lambda u+f\left(x,u),\hspace{1.0em} & \hspace{0.1em}\text{in}\hspace{0.1em}\hspace{0.33em}\Omega ,\\ u=0,\hspace{1.0em} & \hspace{0.1em}\text{in}\hspace{0.1em}\hspace{0.33em}{{\mathbb{R}}}^{N}\backslash \Omega \right.\end{array}\right. Multiplicity of nontrivial solutions is obtained when the parameter is near the eigenvalue of the fractional Laplace operator without Ambrosetti and Rabinowitz condition for the nonlinearity. Our methods are the combination of minimax method, bifurcation theory, and Morse theory.
    Type of Medium: Online Resource
    ISSN: 2191-950X
    URL: Article
    DOI: 10.1515/anona-2022-0281
    Language: English
    Publisher: Walter de Gruyter GmbH
    Publication Date: 2023
    detail.hit.zdb_id: 2645915-2
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  • 4
    Online Resource
    Online Resource
    Rosavin exerts an antitumor role and inactivates the MAPK/ERK pathway in small-cell lung carcinoma in vitro
    Walter de Gruyter GmbH ; 2023
    In:  Acta Pharmaceutica Vol. 73, No. 2 ( 2023-06-01), p. 269-280
    Details
    In: Acta Pharmaceutica, Walter de Gruyter GmbH, Vol. 73, No. 2 ( 2023-06-01), p. 269-280
    Abstract: This study attempts to explore the function and mechanism of action of rosavin in small-cell lung cancer (SCLC) in vitro . The viability and clone formation of SCLC cells were assessed using cell counting kit-8 and colony formation assays, respectively. Apoptosis and cell cycle were detected using flow cytometry and cell cycle analysis, respectively. Wound healing and transwell assays were performed to evaluate the migration and invasion of SCLC cells. Besides, protein levels of p-ERK, ERK, p-MEK and MEK were determined using Western blot analysis. Rosavin repressed the viability and clone formation of SCLC cells, and promoted apoptosis and G 0 /G 1 arrest of SCLC cells. At the same time, rosavin suppressed migration and invasion of SCLC cells. Moreover, protein levels of p-ERK/ERK and p-MEK/MEK were decreased after rosavin addition in SCLC cells. Rosavin impaired malignant behaviors of SCLC cells, which may be associated with inhibition of the MAPK/ERK pathway in vitro .
    Type of Medium: Online Resource
    ISSN: 1846-9558
    URL: Article
    DOI: 10.2478/acph-2023-0015
    Language: English
    Publisher: Walter de Gruyter GmbH
    Publication Date: 2023
    detail.hit.zdb_id: 2255569-9
    SSG: 15,3
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  • 5
    Online Resource
    Online Resource
    Erosion behaviour of B 4 C/TiB 2 /Mo ceramic nozzles
    Walter de Gruyter GmbH ; 2024
    In:  International Journal of Materials Research Vol. 0, No. 0 ( 2024-05-27)
    Details
    In: International Journal of Materials Research, Walter de Gruyter GmbH, Vol. 0, No. 0 ( 2024-05-27)
    Abstract: B 4 C/TiB 2 /Mo ceramic nozzles were obtained by uniaxial hot-pressing. The mechanical properties and erosion behaviour of B 4 C/TiB 2 /Mo ceramic nozzles were investigated. Volume erosion rate was used to rank the erosion behaviour of the B 4 C/TiB 2 /Mo ceramic nozzles. The relationship between mechanical properties and the volume erosion rate of the nozzles was discussed. X-ray diffraction analysis showed that in-situ reaction to form TiB 2 happened during sintering. Scanning electron microscopy was employed to observe the fracture surfaces and eroded surfaces of B 4 C/TiB 2 /Mo ceramic nozzles. A model of erodent particles and nozzle during the erosion test was established using the JH2 model. The maximum von Mises stresses on the entry, middle and exit surfaces of the nozzle were calculated. The result showed that the hardness played a key role in influencing the erosion behaviour of B 4 C/TiB 2 /Mo ceramic nozzles. Erosion mechanisms of B 4 C/TiB 2 /Mo ceramic nozzles at the entry, middle and exit bore area were mainly brittle fracture, fracture & plowing and micro-plowing, respectively.
    Type of Medium: Online Resource
    ISSN: 1862-5282 , 2195-8556
    URL: Article
    DOI: 10.1515/ijmr-2023-0298
    RVK:
    ZG 1100
    Language: English
    Publisher: Walter de Gruyter GmbH
    Publication Date: 2024
    detail.hit.zdb_id: 2232675-3
    detail.hit.zdb_id: 2128058-7
    detail.hit.zdb_id: 203021-4
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  • 6
    Online Resource
    Online Resource
    Ti 3 C 2 T x MXenes-based flexible materials for electrochemical energy storage and solar energy conversion
    Walter de Gruyter GmbH ; 2022
    In:  Nanophotonics Vol. 11, No. 14 ( 2022-06-27), p. 3215-3245
    Details
    In: Nanophotonics, Walter de Gruyter GmbH, Vol. 11, No. 14 ( 2022-06-27), p. 3215-3245
    Abstract: Over the past decade, two-dimensional (2D) Ti 3 C 2 T x MXenes demonstrated attractive characteristics such as high electrical conductivity, tunable layered structure, controllable interfacial chemical composition, high optical transparency, and excellent electromagnetic wave absorption, enabling Ti 3 C 2 T x MXenes as promising electrode materials in energy storage devices. Among these devices, flexible energy storage devices have attracted wide attention and developed rapidly due to the synchronously excellent electrochemical and mechanical properties. This review summarizes the recent progress of Ti 3 C 2 T x MXenes pertaining to novel material preparation and promising applications in energy storage and conversion including batteries, supercapacitors, solar cells, and solar steam generation. This work aims to provide an in-depth and reasonable understanding of the relationship between the unique nanostructure/chemical composition of Ti 3 C 2 T x MXenes and competitive electrochemical properties, which will facilitate the development of 2D Ti 3 C 2 T x MXenes for practical energy storage and solar energy conversion devices.
    Type of Medium: Online Resource
    ISSN: 2192-8614
    URL: Article
    DOI: 10.1515/nanoph-2022-0228
    Language: English
    Publisher: Walter de Gruyter GmbH
    Publication Date: 2022
    detail.hit.zdb_id: 2674162-3
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  • 7
    Online Resource
    Online Resource
    Potential role of ACE2 in coronavirus disease 2019 (COVID-19) prevention and management
    Walter de Gruyter GmbH ; 2020
    In:  Journal of Translational Internal Medicine Vol. 8, No. 1 ( 2020-05-09), p. 9-19
    Details
    In: Journal of Translational Internal Medicine, Walter de Gruyter GmbH, Vol. 8, No. 1 ( 2020-05-09), p. 9-19
    Abstract: COVID-19 is the current public health threat all over the world. Unfortunately, there is no specific prevention and treatment strategy for this disease. We aim to explore the potential role of angiotensin-converting enzyme 2 (ACE2) in this regard through this literature review. As a crucial enzyme of renin-angiotensin-aldosterone system (RAAS), ACE2 not only mediates the virus entry but also affects the pathophysiological process of virus-induced acute lung injury (ALI), as well as other organs’ damage. As interaction of COVID-19 virus spike and ACE2 is essential for virus infection, COVID-19-specific vaccine based on spike protein, small molecule compound interrupting their interaction, human monoclonal antibody based on receptor-binding domain, and recombinant human ACE2 protein (rhuACE2) have aroused the interests of researchers. Meanwhile, ACE2 could catalyze angiotensin II (Ang II) to form angiotensin 1-7 (Ang 1-7), thus alleviates the harmful effect of Ang II and amplifies the protection effect of Ang1-7. ACE inhibitor and angiotensin II receptor blocker (ARB) have been shown to increase the level of expression of ACE2 and could be potential strategies in protecting lungs, heart, and kidneys. ACE2 plays a very important role in the pathogenesis and pathophysiology of COVID-19 infection. Strategies targeting ACE2 and its ligand, COVID-19 virus spike protein, may provide novel method in the prevention and management of novel coronavirus pneumonia.
    Type of Medium: Online Resource
    ISSN: 2224-4018
    URL: Article
    DOI: 10.2478/jtim-2020-0003
    Language: English
    Publisher: Walter de Gruyter GmbH
    Publication Date: 2020
    detail.hit.zdb_id: 2861892-0
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  • 8
    Online Resource
    Online Resource
    Mild acute stress prevents the memory impairment induced by long-term isoflurane anesthesia
    Walter de Gruyter GmbH ; 2022
    In:  Translational Neuroscience Vol. 13, No. 1 ( 2022-12-01), p. 421-429
    Details
    In: Translational Neuroscience, Walter de Gruyter GmbH, Vol. 13, No. 1 ( 2022-12-01), p. 421-429
    Abstract: Long-term isoflurane anesthesia exposure could result in postoperative cognitive dysfunction (POCD). Preoperative stress is also reported to be a risk factor of POCD. However, it is unknown whether acute stress could impair memory after long-term isoflurane anesthesia. Methods In this study, we categorized the mice with acute stress into mild (30 min restraint stress), moderate (60 min restraint stress), and severe (120 min restraint stress) stress groups and then we used Open-Field Test (OFT) to detect whether different scales of acute restraint stress successfully induced acute stress in mice. The memory performance of mice was measured using contextual and cued memory test, and the brain-derived neurotrophic factor protein levels of hippocampus was detected by Western blot. Results We verified that mild stress has pro-cognitive effect, but severe stress has amnestic effect. Moreover, we found that mild and moderate other than severe acute stress could partially attenuate the memory impairment induced by long-term isoflurane anesthesia. Conclusion Mild and moderate acute stress could partially attenuate the memory impairment induced by long-term isoflurane anesthesia.
    Type of Medium: Online Resource
    ISSN: 2081-6936
    URL: Article
    DOI: 10.1515/tnsci-2022-0261
    Language: English
    Publisher: Walter de Gruyter GmbH
    Publication Date: 2022
    detail.hit.zdb_id: 2581219-1
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