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  • 1
    Online Resource
    Online Resource
    Walter de Gruyter GmbH ; 2004
    In:  International Journal of Adolescent Medicine and Health Vol. 16, No. 4 ( 2004-10)
    In: International Journal of Adolescent Medicine and Health, Walter de Gruyter GmbH, Vol. 16, No. 4 ( 2004-10)
    Type of Medium: Online Resource
    ISSN: 2191-0278 , 0334-0139
    Language: Unknown
    Publisher: Walter de Gruyter GmbH
    Publication Date: 2004
    detail.hit.zdb_id: 2602424-X
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  • 2
    Online Resource
    Online Resource
    Walter de Gruyter GmbH ; 2021
    In:  Journal of Pediatric Endocrinology and Metabolism Vol. 34, No. 4 ( 2021-04-27), p. 495-502
    In: Journal of Pediatric Endocrinology and Metabolism, Walter de Gruyter GmbH, Vol. 34, No. 4 ( 2021-04-27), p. 495-502
    Abstract: Recent studies have shown a potential link between chronic exposure to Bisphenol A (BPA) and exogenous obesity, the prevalence of which has been increasing dramatically in all age groups and particularly among children in the last decades. In this study, we aimed at comparing BPA exposure levels between controls and otherwise healthy, drug-naive, pre-pubertal children having exogenous obesity with/without metabolic syndrome. Methods A total of 63 pre-pubertal children with exogenous obesity whom 27 of them having metabolic syndrome attending Hacettepe University Ihsan Dogramaci Children’s Hospital were included in this study. The control group consisted of 34 age- and sex-matched healthy children with no significant underlying medical conditions. Urinary BPA levels were measured using LC-MS/MS (high-performance liquid chromatography coupled with tandem mass spectrometry) methodology. Results Urinary BPA levels among obese children were significantly higher than those of the control group (median: 22.9 μg/g-creatinine and 6.9 μg/g-creatinine, respectively; p=0.0001). When adjusted with generalized linear models for age, gender and z scores of body mass index, obese children having metabolic syndrome had significantly higher urinary BPA levels than obese children without metabolic syndrome and both obese groups had considerably elevated levels of urinary BPA than the controls (estimated marginal mean ± standard error: 42.3 ± 7.4 μg/g-creatinine, 22.6 ± 3.5 μg/g-creatinine and 12.1 ± 2.5 μg/g-creatinine, respectively, p=0.0001) Conclusions This study shows much higher BPA exposure among obese children with metabolic syndrome during the prepubertal period.
    Type of Medium: Online Resource
    ISSN: 2191-0251 , 0334-018X
    Language: English
    Publisher: Walter de Gruyter GmbH
    Publication Date: 2021
    detail.hit.zdb_id: 2583847-7
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  • 3
    Online Resource
    Online Resource
    Walter de Gruyter GmbH ; 2018
    In:  Journal of Pediatric Endocrinology and Metabolism Vol. 31, No. 8 ( 2018-08-28), p. 829-836
    In: Journal of Pediatric Endocrinology and Metabolism, Walter de Gruyter GmbH, Vol. 31, No. 8 ( 2018-08-28), p. 829-836
    Abstract: Bisphenol-A (BPA) is one of the most abundantly produced chemicals globally. Concerns have been raised about BPA’s possible role in the pathogenesis of type 1 diabetes mellitus (T1DM). The main aim of the current study was to evaluate the possible association between BPA exposure and T1DM. The second aim was to investigate children’s possible BPA exposure routes in Turkey. Methods: A total of 100 children aged between 5 and 18 years including 50 children with T1DM and 50 healthy children were included. Urinary BPA levels of all children were measured using high-performance liquid chromatography. Mothers of children enrolled in the study were also requested to complete a survey that included questions on the sociodemographic characteristics, medical history and possible BPA exposure routes of their children. Results: In the T1DM group, urinary BPA levels were slightly higher compared to the control group, but this difference was not significant (p=0.510). However, there was an inverse relationship between current urinary BPA levels and birth weight. It was found that the use of plastic kettles and the consumption of dairy products in plastic boxes significantly increased the urinary BPA concentrations in all subjects. Conclusions: Although there was no significant association between urinary BPA levels and T1DM, we found an inverse relationship between current urinary BPA levels and birth weight. This finding might be important for prenatal exposure, and further prospective research must be conducted. Also, the use of plastic kettles, which has not been mentioned much in the literature before, was found to be an important exposure route for BPA.
    Type of Medium: Online Resource
    ISSN: 2191-0251 , 0334-018X
    Language: English
    Publisher: Walter de Gruyter GmbH
    Publication Date: 2018
    detail.hit.zdb_id: 2583847-7
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  • 4
    Online Resource
    Online Resource
    Walter de Gruyter GmbH ; 2010
    In:  Journal of Pediatric Endocrinology and Metabolism Vol. 23, No. 8 ( 2010-01)
    In: Journal of Pediatric Endocrinology and Metabolism, Walter de Gruyter GmbH, Vol. 23, No. 8 ( 2010-01)
    Type of Medium: Online Resource
    ISSN: 0334-018X , 2191-0251
    Language: Unknown
    Publisher: Walter de Gruyter GmbH
    Publication Date: 2010
    detail.hit.zdb_id: 2583847-7
    Location Call Number Limitation Availability
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  • 5
    Online Resource
    Online Resource
    Walter de Gruyter GmbH ; 2020
    In:  Journal of Pediatric Endocrinology and Metabolism Vol. 33, No. 9 ( 2020-09-25), p. 1203-1211
    In: Journal of Pediatric Endocrinology and Metabolism, Walter de Gruyter GmbH, Vol. 33, No. 9 ( 2020-09-25), p. 1203-1211
    Abstract: Obesity and obesity-related diseases are one of the common health problems worldwide and have also been proposed to be important predictors of blood pressure and cardiovascular disease risk. The aim of our study is to determine the utility of different anthropometric measurements (body mass index [BMI], skinfold thickness [SFT] , waist circumference [WC], mid-upper arm circumference [MUAC] , arm circumference-height ratio [AHtR], and waist circumference-height ratio [WHtR] ) as markers of hypertension (HT) risk in adolescents. Methods In this cross-sectional study, 544 participants aged between 12 and 13 years were included. Anthropometric measurements and blood pressure of participants were measured. The association of different anthropometric measurements with blood pressure was evaluated. Results The frequency of both elevated blood pressure and HT was 30.2%. Biceps, triceps, and suprailiac SFT have an impact on HT in girls but only suprailiac SFT in boys. WC measurements above the 85th percentile were strongly correlated with HT conditions, and this relationship was stronger in boys than in girls (3.3 vs. 2.6 fold). MUAC, WHtR, and AHtR measurements also have strong correlation with HT in boys but only WHtR has a poor relation in girls. In boys and girls with obesity, there was a positive association between obesity and blood pressures. Conclusions Not only age-related BMI z scores but also a number of other anthropometric measurements, such as WC, SFT, MUAC, WHtR, and AHtR, could have an influence on high blood pressure. The influence changes with gender during adolescence.
    Type of Medium: Online Resource
    ISSN: 2191-0251 , 0334-018X
    Language: English
    Publisher: Walter de Gruyter GmbH
    Publication Date: 2020
    detail.hit.zdb_id: 2583847-7
    Location Call Number Limitation Availability
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  • 6
    Online Resource
    Online Resource
    Walter de Gruyter GmbH ; 2006
    In:  International Journal of Adolescent Medicine and Health Vol. 18, No. 4 ( 2006-10)
    In: International Journal of Adolescent Medicine and Health, Walter de Gruyter GmbH, Vol. 18, No. 4 ( 2006-10)
    Type of Medium: Online Resource
    ISSN: 2191-0278 , 0334-0139
    Language: Unknown
    Publisher: Walter de Gruyter GmbH
    Publication Date: 2006
    detail.hit.zdb_id: 2602424-X
    Location Call Number Limitation Availability
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