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  • 1
    Online Resource
    Online Resource
    Computed Tomography Findings in a Case of Giant Frontal Sinus Mucopyocele in a Dog
    Walter de Gruyter GmbH ; 2018
    In:  Acta Veterinaria Vol. 68, No. 2 ( 2018-06-01), p. 232-238
    Details
    In: Acta Veterinaria, Walter de Gruyter GmbH, Vol. 68, No. 2 ( 2018-06-01), p. 232-238
    Abstract: A 16-month-old male crossbreed dog, which suffered a previous traumatic incident, was presented for evaluation of a chronic fluctuant right supraorbitary mass. On computed tomography, a well-defined, expansile, hypodense mass, showing a thin peripheral enhancement was occupying the right frontal sinus and extending into the cranial cavity. Imaging findings, bacteriological culture, and histopathology of the surgically excised mass were consistent with a frontal sinus mucopyocele. Frontal sinus mucopyocele should be included as a differential diagnosis for a well-marginated expansile frontal sinus mass, especially when present in young animals or/and associated with a previous craniofacial trauma.
    Type of Medium: Online Resource
    ISSN: 1820-7448
    URL: Article
    DOI: 10.2478/acve-2018-0020
    Language: English
    Publisher: Walter de Gruyter GmbH
    Publication Date: 2018
    detail.hit.zdb_id: 2380825-1
    SSG: 22
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  • 2
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    Online Resource
    Focused transhepatic electroporation mediated by hypersaline infusion through the portal vein in rat model. Preliminary results on differential conductivity
    Walter de Gruyter GmbH ; 2017
    In:  Radiology and Oncology Vol. 51, No. 4 ( 2017-11-29), p. 415-421
    Details
    In: Radiology and Oncology, Walter de Gruyter GmbH, Vol. 51, No. 4 ( 2017-11-29), p. 415-421
    Abstract: Spread hepatic tumours are not suitable for treatment either by surgery or conventional ablation methods. The aim of this study was to evaluate feasibility and safety of selectively increasing the healthy hepatic conductivity by the hypersaline infusion (HI) through the portal vein. We hypothesize this will allow simultaneous safe treatment of all nodules by irreversible electroporation (IRE) when applied in a transhepatic fashion. Material and methods Sprague Dawley (Group A, n = 10) and Athymic rats with implanted hepatic tumour (Group B, n = 8) were employed. HI was performed (NaCl 20%, 3.8 mL/Kg) by trans-splenic puncture. Deionized serum (40 mL/Kg) and furosemide (2 mL/Kg) were simultaneously infused through the jugular vein to compensate hypernatremia. Changes in conductivity were monitored in the hepatic and tumour tissue. The period in which hepatic conductivity was higher than tumour conductivity was defined as the therapeutic window (TW). Animals were monitored during 1-month follow-up. The animals were sacrificed and selective samples were used for histological analysis. Results The overall survival rate was 82.4% after the HI protocol. The mean maximum hepatic conductivity after HI was 2.7 and 3.5 times higher than the baseline value, in group A and B, respectively. The mean maximum hepatic conductivity after HI was 1.4 times higher than tumour tissue in group B creating a TW to implement selective IRE. Conclusions HI through the portal vein is safe when the hypersaline overload is compensated with deionized serum and it may provide a TW for focused IRE treatment on tumour nodules.
    Type of Medium: Online Resource
    ISSN: 1581-3207
    URL: Article
    DOI: 10.1515/raon-2017-0051
    Language: English
    Publisher: Walter de Gruyter GmbH
    Publication Date: 2017
    detail.hit.zdb_id: 2134813-3
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