In:
Advanced Materials Research, Trans Tech Publications, Ltd., Vol. 1033-1034 ( 2014-10), p. 555-557
Abstract:
Tert-butyl (4 R )-4-(methoxymethylcarbamoyl)-2,2-dimethylthiazolidine-3-carboxylate, an key intermediate of the natural product Biotin which is a water-soluble vitamin, involved in an essential part of the metabolic cycle causing catalytic fixation of carbon dioxide in the biosynthesis of fatty acids, sugars, and α-amino acids, was synthesized from L -cystine in overall yield 54% through three steps. The study including acetonization, Boc protection, N-methoxy-N-methyl amidation.
Type of Medium:
Online Resource
ISSN:
1662-8985
DOI:
10.4028/www.scientific.net/AMR.1033-1034
DOI:
10.4028/www.scientific.net/AMR.1033-1034.555
Language:
Unknown
Publisher:
Trans Tech Publications, Ltd.
Publication Date:
2014
detail.hit.zdb_id:
2265002-7
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