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  • The Turkish Journal of Pediatrics  (2)
  • 1
    In: The Turkish Journal of Pediatrics, The Turkish Journal of Pediatrics, Vol. 64, No. 2 ( 2022), p. 255-
    Abstract: Background. In this study, we aimed to evaluate the serum neurotensin (NT) levels and their relationships with self-reported anxiety, emotion regulation skills and impulsivity in healthy and obese adolescents. Methods. Adolescents who gained weight between 12- 17 years of age and who were above the 95th percentile (p) for body mass index (BMI) 〉 95p were compared with age- and gender-matched healthy adolescents with a BMI of 3-85 p. Anthropometric measurements were performed, and serum NT levels were analyzed with ELISA method in all participants. Barrat Impulsivity Scale-11 (BIS-11), Screen for Child Anxiety Related Disorders (SCARED) and Difficulties in Emotion Regulation Scale (DERS) were used for evaluating self-reported impulsivity, anxiety and emotion regulation. MANOVA with follow-up univariate ANOVAs (Bonferroni corrected) were used for group comparisons. P was set at 0.05 (two-tailed). Results. Sixty-five obese and 65 healthy adolescents were included in the study. In the obese group, NT levels were significantly elevated compared to the control group. Self-reported emotion-regulation difficulties, anxiety and impulsivity were significantly elevated among obese adolescents. Serum NT levels among the obese group were positively correlated with emotion dysregulation and impulsivity scores. Conclusions. In this study, we found emotional dysregulation, anxiety, impulsivity, and serum NT levels were significantly elevated among obese adolescents compared to controls. NT levels in the obese group correlated with impulsivity and emotion dysregulation. Further studies should evaluate the potential role of NT in the etiology of psychopathology among adolescents who are obese.
    Type of Medium: Online Resource
    ISSN: 0041-4301
    Language: Unknown
    Publisher: The Turkish Journal of Pediatrics
    Publication Date: 2022
    detail.hit.zdb_id: 2120977-7
    Location Call Number Limitation Availability
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  • 2
    Online Resource
    Online Resource
    The Turkish Journal of Pediatrics ; 2022
    In:  The Turkish Journal of Pediatrics Vol. 64, No. 2 ( 2022), p. 239-
    In: The Turkish Journal of Pediatrics, The Turkish Journal of Pediatrics, Vol. 64, No. 2 ( 2022), p. 239-
    Abstract: Background. Current studies claim that peptides such as leptin, adiponectin, ghrelin, and nesfatin-1 found in breast milk may be responsible for the growth of infants. Therefore, we aimed to determine the association between breast milk total ghrelin and nesfatin-1 levels and anthropometric measurements of infants who were small for gestational age (SGA). Methods. 20 SGA and 20 appropriate for gestational age (AGA) infants were enrolled in the study. Anthropometric measurements of infants were carried out at birth, 1st, and 4th months. In addition, total ghrelin and nesfatin-1 levels in the breast milk were concomitantly measured. Results. Total ghrelin at the 4th month in breast milk waslower-level in the SGA group (p=0.015). In both groups, nesfatin-1 levels at the 4th month were lower than the values at the 1st month. Additionally, nesfatin-1 levels of SGA infants at the 4th month were higher (p=0.035). Conclusions. Breast milk total ghrelin and nesfatin-1 levels differed in both groups, and it is probably referred to the growth discrepancy of these infants during the first months of life. Furthermore, we consider that higher breast milk nesfatin-1 levels at the 4th month may be a preventive against obesity in SGA infants who have potential risk for obesity in childhood and adulthood.
    Type of Medium: Online Resource
    ISSN: 0041-4301
    Language: Unknown
    Publisher: The Turkish Journal of Pediatrics
    Publication Date: 2022
    detail.hit.zdb_id: 2120977-7
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
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