In:
Philosophical Transactions of the Royal Society B: Biological Sciences, The Royal Society, Vol. 368, No. 1620 ( 2013-06-19), p. 20120362-
Abstract:
The last few years have seen the development of large efforts for the analysis of genome function, especially in the context of genome variation. One of the most prominent directions has been the extensive set of studies on expression quantitative trait loci (eQTLs), namely, the discovery of genetic variants that explain variation in gene expression levels. Such studies have offered promise not just for the characterization of functional sequence variation but also for the understanding of basic processes of gene regulation and interpretation of genome-wide association studies. In this review, we discuss some of the key directions of eQTL research and its implications.
Type of Medium:
Online Resource
ISSN:
0962-8436
,
1471-2970
DOI:
10.1098/rstb.2012.0362
Language:
English
Publisher:
The Royal Society
Publication Date:
2013
detail.hit.zdb_id:
1462620-2
SSG:
12
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