In:
Korean Journal of Anesthesiology, The Korean Society of Anesthesiologists, Vol. 77, No. 3 ( 2024-06-01), p. 374-383
Abstract:
Background: This study aimed to compare the analgesic effects of programmed intermittent epidural boluses (PIEB) and continuous epidural infusion (CEI) for postoperative analgesia after elective cesarean section (CS).Methods: Seventy-four women who underwent elective CS were randomized to receive either PIEB or CEI. The PIEB group received 4 ml-intermittent boluses of 0.11% ropivacaine every hour at a rate of 120 ml/h. The CEI group received a constant rate of 4 ml/h of 0.11% ropivacaine. The primary outcome was the pain score at rest at 36 h after CS. Secondary outcomes included the pain scores during mobilization, time-weighted pain scores, the incidence of motor blockade, and complications-related epidural analgesia during 36 h after CS.Results: The pain score at rest at 36 h after CS was significantly lower in the PIEB group compared with that in the CEI group (3.0 vs. 0.0; median difference: 2, 95% CI [1, 2], P 〈 0.001). The mean time-weighted pain scores at rest and during mobilizations were also significantly lower in the PIEB group than in the CEI group (pain at rest; mean difference [MD]: 37.5, 95% CI [24.6, 50.4] , P 〈 0.001/pain during mobilization; MD: 56.6, 95% CI [39.8, 73.5], P 〈 0.001). The incidence of motor blockade was significantly reduced in the PIEB group compared with that in the CEI group (P 〈 0.001).Conclusions: PIEB provides superior analgesia with less motor blockade than CEI in postpartum women after CS, without any apparent adverse events.
Type of Medium:
Online Resource
ISSN:
2005-6419
,
2005-7563
Language:
English
Publisher:
The Korean Society of Anesthesiologists
Publication Date:
2024
detail.hit.zdb_id:
2557340-8
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