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  • 1
    Electronic Resource
    Electronic Resource
    HighT c superconductive materials: Bulk or twinned domain/grain boundary percolative network superconductors? (1988)
    Springer
    The European physical journal 70 (1988), S. 9-13 
    Details
    ISSN: 1434-6036
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract We have studied the physical properties of Y−Ba−Cu−Oxide superconducting materials by using Levitation, AC-susceptibility, macroscopic conductivity, Scanning Tunneling Microscopy (STM) local conductivity, Scanning Electron Microscope (SEM), X-rays, and Hall effect experimental techniques. Our results tend to indicate systematically that the grains formed in the synthesis do not show bulk superconductivity but rather are superconductors at the domain boundaries of the orthorhombic phase. It seems that a coexistence of semiconductor and metallic regions are formed at the twinned domain boundaries. The pellets become superconductors when the grains form clusters and are in intimate contact. This seems to suggest that the bulk of the grains is semiconducting and that a conducting percolative network of grain and domain boundaries may be responsible for the superconductivity. To understand the observed constant high transition temperature we propose a model of semiconductor-metal-semiconductor boundaries that give rise to superconductivity in a model like that of Little, Ginzburg, and Allender-Bray-Bardeen (1).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01320531
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  • 2
    Electronic Resource
    Electronic Resource
    Sequential intravenous-oral ciprofloxacin plus amoxycillin/clavulanic acid shortens hospital stay in infected non severe neutropenic patients (1997)
    Springer
    Hematology and cell therapy 39 (1997), S. 223-227 
    Details
    ISSN: 1279-8509
    Keywords: Infection ; Sequential intravenous-oral antibiotics ; Ciprofloxacin, amoxycillin-clavulanic acid
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The objective of this study was to determine the efficacy and safety of the combination ciprofloxacin plus amoxicillin/clavulanic acid as an empirical treatment of infection in hematologic patients without severe neutropenia. These drugs allowed us to carry out a sequential therapy, first intravenously and later orally, so that the patient could be discharged as soon as there was a response. Serum concentrations of ciprofloxacin were monitored in this study. Forty seven of the sixty-six patients included (71%) responded to the treatment with no differences between the dosages of ciprofloxacin employed (600-900 mg daily in two or three divided doses). In the patients who responded, the signs and symptoms of infection lasted only three days, which could allow a short hospital stay (median of six days). In the first pre and post-dose serum samples, ciprofloxacin concentrations were significantly higher when the drug was administered every 8 h. Nevertheless, 72 h after the beginning of treatment, they had leveled out in either 8 and 12 h schemes. The toxicity of the treatment was very light, with only four cases with adverse effects, grades I and II. This data suggests that the employed combination is effective and safe and can considerably decrease costs incurred through the admission of hematologic patients with serious infections but without severe neutropenia.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s00282-997-0223-0
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  • 3
    Electronic Resource
    Electronic Resource
    Prevalence of antinuclear antibodies in patients with habitual abortion and in normal and toxemic pregnancies (1984)
    Springer
    Rheumatology international 4 (1984), S. 87-89 
    Details
    ISSN: 1437-160X
    Keywords: Antinuclear antibodies ; Habitual abortion ; Toxemic pregnancies ; Systemic lupus erythematosus
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The prevalence of antinuclear antibodies (ANA) was investigated in the sera from patients with habitual abortion (HA) and in normal (NP) and toxemic pregnancies (TP). ANAs were more prevalent in patients with HA (30%) as compared with TP (15%) and the control group (6.6%). Only one patient, from the HA group, fulfilled four criteria for systemic lupus erythematosus (SLE). Most other patients with positive ANAs had some of the criteria for SLE, but none of the ANA negative patients had any of them. These studies suggest that there is a high prevalence of ANA in our group of women with HA and their identification may help to identify those patients who may eventually develop SLE which has been reported to be preceded in many women by repeated spontaneous abortions. In addition, immunological factors, at least in some cases, could play a role in the pathogenesis of HA.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00541202
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  • 4
    Electronic Resource
    Electronic Resource
    Piezoelectric Pb0.7La0.2TiO3 prepared by pulsed laser deposition on (100)InP (1999)
    Springer
    Applied physics 69 (1999), S. S827 
    Details
    ISSN: 1432-0630
    Keywords: PACS: 81.15.Fg; 81.15.Np; 77.84.Dy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Abstract. La-modified PbTiO3 (PLT) thin films have been deposited by pulsed laser deposition on (100)InP substrates. The nominal target composition was selected to optimize piezoelectric properties of the material. It is shown that PLT deposition on as-received InP produces amorphous PLT films because of the presence of a native oxide on the substrate. PLT films deposited on bare InP have poor adhesion as a result of the surface reoxidation of the substrate due to the high oxygen pressure required for the deposition of stoichiometric PLT. To prevent substrate oxidation, several buffer oxides (CeO2, ZrO2, SrO, Y-stabilized ZrO2, MgO, and SrTiO3) have been grown in vacuum on (100)InP. Highest-quality heteroepitaxy was found with Y-stabilized ZrO2 (YSZ), being 〈100〉{100} YSZ∥〈100〉{100}  InP oriented. The PLT deposited on this buffer layer is oriented with the [101] direction perpendicular to the substrate surface plane.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003390051540
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  • 5
    Electronic Resource
    Electronic Resource
    Alternating mini-BEAM/ESHAP as salvage therapy for refractory non-Hodgkin's lymphomas (1997)
    Springer
    Annals of hematology 74 (1997), S. 79-82 
    Details
    ISSN: 1432-0584
    Keywords: Key words Non-Hodgkin's lymphoma ; Refractory ; Salvage therapy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  Mini-BEAM and ESHAP are two non-cross-resistant salvage regimens that have been used separately in patients with lymphoma. The aim of the present study was to investigate the efficacy of the combination of these two regimens, administered in alternating cycles, as salvage therapy for refractory non-Hodgkin's lymphoma (NHL) patients. A total of 28 patients were included in the study: 14 patients were primary refractory, seven were partial responders, and seven were in relapse. The alternating cycles of mini-BEAM and ESHAP were given until there was maximum response or progression. The overall response rate to mini-BEAM/ESHAP was 39%; 25% of patients achieved a complete response and 14% a partial response. Nevertheless, it should be noted that none of the primary refractory patients responded to this protocol. Nine of the 11 patients who responded to mini-BEAM/ESHAP were consolidated with autologous transplantation using BEAM as a conditioning regimen. The survival at 3 years in this group of 11 patients who responded to the salvage regimen is 64%, with a disease-free survival of 67% at 2 years. No major toxic effects were observed with mini-BEAM/ESHAP. Myelosuppression was the most frequent complication, especially with the mini-BEAM cycles. Other toxicities were infrequent and no treatment-related deaths were observed. These results suggest that alternating mini-BEAM/ESHAP chemotherapy is a safe regimen that is effective in partial responders or relapsing patients with NHL who have sensitive disease, but not in primary refractory patients. Moreover, although this therapy has a potential advantage, combining as it does two non-cross-resistant regimens, it does not seem superior to ESHAP alone.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002770050261
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