GLORIA

GEOMAR Library Ocean Research Information Access

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • Springer  (25)
Document type
Keywords
Publisher
Years
  • 1
    Electronic Resource
    Electronic Resource
    Evidence of impaired polymorphonuclear leucocyte phagocytic functions and chemiluminescence response in rheumatoid arthritis (1994)
    Springer
    Rheumatology international 13 (1994), S. 251-255 
    Details
    ISSN: 1437-160X
    Keywords: Polymorphonuclear leucocytes ; Phagocytosis ; Respiratory burst ; Rheumatoid arthritis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In this study, the phagocytic uptake of 3H-thymidine-labelled Staphylococcus aureus and bacterial killing (Bk) by polymorphonuclear leucocytes (PMN) from patients with rheumatoids arthritis (RA) were investigated and compared to the luminol-enhanced chemiluminescence response (LCL) to phorbolmyristic acetate (PMA), a receptor and second message-independent activator of respiratory burst activity in definite or classical rheumatoid arthritis (RA), with regard to the inflammatory activity of the disease process, and compared to patients with osteoarthritis (OA) and healthy controls. PMN of RA patients showed a significant reduction in uptake (57.8±4.4%) and less Bk capacity (27.3±4.2%) compared to OA patients (uptake 71.4±4.3%, Bk 20.6±2.9%; P〈0.001) and controls (uptake 73.2±5.2%, Bk19.3±4.2%;P〈0.001). In contrast, PMN LCL response was markedly enhanced in RA patients compared to OA patients (P〈0.001) and controls (P〈0.001). There was no significant influence of inflammatory activity on various PMN functions in RA and no difference was found between OA and control subjects. These data clearly demonstrated impaired PMN phagocytic functions (uptake, Bk) and enhanced LCL in RA, suggesting “priming” and/or activated peripheral blood PMN, which might be of clinical importance concerning altered host defence in these patients.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00290204
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    UV-Absorptionsspektren von Benzolsulfonamiden. II (1954)
    Springer
    Monatshefte für Chemie 85 (1954), S. 168-181 
    Details
    ISSN: 1434-4475
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Zusammenfassung Die UV-Absorptionsspektren von acht N4-substituierten, chemotherapeutisch verwendeten Sulfonamiden und von sieben ihrer „Molekülbestandteile”, sowie von zwei weiteren Präparaten mit sulfonamidartiger Wirkung werden in wäßrigen Lösungen bei verschiedenen pH-Werten ermittelt. Auf Grund der Änderungen der Absorption, die durch die Variation des pH-Wertes hervorgerufen werden, können die Spektren der Sulfonamide charakterisiert werden.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00900437
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Einfluss von Streptomycin und von Tetracyclinen auf die Entwicklung keimender Samen (1955)
    Springer
    Cellular and molecular life sciences 11 (1955), S. 108-110 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Euler (1947) andM. L. Stein (1953) had observed that germinating seeds of barley, rye, wheat and other grasses are colourless when exposed to solutions containing more than 0.2% of streptomycin or dihydrostreptomycin. These plants are not inhibited in growth. The chlorophyll already formed is not destroyed by streptomycin. The present authors describe the bleaching effect on germinating seeds of chlortetracycline and tetracycline. These antibiotics inhibit or reduce the formation of chlorophyll in germinating seeds but the authors could not obtain this inhibition without toxic effects (reduced growth). Contrary to streptomycin, the tetracyclines are not able to precipitate nucleic acids and nucleoproteins.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02161695
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    Über die Variabilität von Inhaltsstoffen in der Geißraute (Galega officinalis L.) (1967)
    Springer
    Naturwissenschaften 54 (1967), S. 205-205 
    Details
    ISSN: 1432-1904
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00594528
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 5
    Electronic Resource
    Electronic Resource
    Über die verschiedene antinekrogene Wirkung von α-Tocopherol und γ-Tocopherol und über das Vorkommen von Tocopherolen in Erbsen (1962)
    Springer
    Naturwissenschaften 49 (1962), S. 134-135 
    Details
    ISSN: 1432-1904
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00621133
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 6
    Electronic Resource
    Electronic Resource
    Hemorrhage into a choledochal cyst in a hemophiliac child (1989)
    Springer
    Pediatric radiology 20 (1989), S. 118-119 
    Details
    ISSN: 1432-1998
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A hemophiliac child presented with acute abdominal pain due to hemorrhage into an unsuspected choledochal cyst. Sonography delineated the cystic mass; hepatobiliary scintigraphy confirmed the diagnosis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02010655
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 7
    Electronic Resource
    Electronic Resource
    Stable states of a non-linear transformation (1967)
    Springer
    Numerische Mathematik 10 (1967), S. 1-19 
    Details
    ISSN: 0945-3245
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02165155
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 8
    Electronic Resource
    Electronic Resource
    Mannitol dehydrogenase from Rhodobacter sphaeroides Si4: subcloning, overexpression in Escherichia coli and characterization of the recombinant enzyme (1997)
    Springer
    Applied microbiology and biotechnology 48 (1997), S. 47-52 
    Details
    ISSN: 1432-0614
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Abstract By polymerase chain reaction mutagenesis techniques, an NdeI restriction site was introduced at the initiation codon of the mannitol dehydrogenase (MDH) gene (mtlK) of Rhodobacter sphaeroides Si4. The mtlK gene was then subcloned from plasmid pAK74 into the NdeI site of the overexpression vector pET24a+ to give plasmid pASFG1. Plasmid pASFG1 was introduced into Escherichia coli BL21(DE3), which was grown in a 1.5-l bioreactor at 37 °C and pH 7.0. Overexpression of MDH in Escherichia coli BL21(DE3) [pASFG1] was determined by enzymatic analysis and sodium dodecyl sulfate (SDS)/polyacrylamide gel electrophoresis. Under standard growth conditions, E. coli produced considerable amounts of a polypeptide that correlated with MDH in SDS gels, but the activity yield was low. Decreasing the growth temperature to 27 °C and omitting pH regulation resulted in a significant increase in the formation of soluble and enzymatically active MDH up to a specific activity of 12.4 U/mg protein and a yield of 26 000 U/l, which corresponds to 0.38 g/l MDH. This was an 87-fold overexpression of MDH compared to that of the natural host R. sphaeroides Si4, and a 236-fold improvement of the volumetric yield. MDH was purified from E. coli BL21(DE3) [pASFG1] with 67% recovery, using ammo-nium sulfate precipitation, hydrophobic interaction chromatography, and gel filtration. Partial characterization of the recombinant MDH revealed no significant differences to the wild-type enzyme.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002530051013
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 9
    Electronic Resource
    Electronic Resource
    Orientation-selected ENDOR of the active center in Chromatium vinosum [NiFe] hydrogenase in the oxidized "ready" state (1999)
    Springer
    JBIC 4 (1999), S. 379-389 
    Details
    ISSN: 1432-1327
    Keywords: Key words [NiFe] hydrogenase ; Chromatium vinosum ; Electron paramagnetic resonance ; Orientation-selected ENDOR ; Proton hyperfine tensors
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract  Electron nuclear double resonance (ENDOR) was applied to study the active site of the oxidized "ready" state, Nir, in the [NiFe] hydrogenase of Chromatium vinosum. The magnetic field dependence of the EPR was used to select specific subsets of molecules contributing to the ENDOR response by stepping through the EPR envelope. Three hyperfine couplings could be clearly followed over the complete field range. Two protons, H1 and H2, display a very similar large isotropic coupling of 12.5 and 12.6 MHz, respectively. Their dipolar coupling is small (2.1 and 1.4 MHz, respectively). A third proton, H3, exhibits a small isotropic coupling of 0.5 MHz and a larger anisotropic contribution of 3.5 MHz. Based on a comparison with structural data obtained from X-ray crystallography of single crystals of hydrogenases from Desulfovibrio gigas and D. vulgaris and the known g-tensor orientation of Nir, an assignment of the 1H hyperfine couplings could be achieved. H1 and H2 were assigned to the β-CH2 protons of the bridging cysteine Cys533 and H3 could belong to a β-CH2 proton of Cys68 or to a protonated cysteine (-SH) of Cys68 or Cys530.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s007750050324
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 10
    Electronic Resource
    Electronic Resource
    Effects of prenatal diazepam on two-way avoidance behavior, swimming navigation and brain levels of benzodiazepine-like molecules in male roman high- and low-avoidance rats (1995)
    Springer
    Psychopharmacology 122 (1995), S. 51-57 
    Details
    ISSN: 1432-2072
    Keywords: Diazepam ; Two-way, active avoidance ; Swimming navigation ; Roman high- and low-avoidance rats ; Benzodiazepine-like molecules ; Genetic selection
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Utilizing psychogenetically selected Roman high- and low-avoidance rats (RHA/Verh and RLA/Verh), the present experiments investigated the effects of prenatally administered vehicle and diazepam (1 and 3 mg/kg per day, SC) on the behavior and neurochemistry of adult, male offspring. Active, two-way avoidance behavior was analyzed in 96 rats, at 6 months of age, and swimming navigation in 68 others, at 11 months. Three weeks after testing, selected brain areas from the latter animals were immunoassayed for benzodiazepine (BZD)-like molecules. The 3 mg/kg dose of diazepam both decreased freezing behavior in the shuttle box and reduced the hippocampal content of BZD-like molecules in the RLA/Verh male rats. Swimming navigation (spatial learning), at which the RLA/Verh rats were more adept, was not specifically affected by prenatal diazepam in either rat line. The possibility exists that an increased hippocampal release of BZD-like substances may be necessary to alter shuttle box behavior in RLA/Verh rats.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02246441
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...