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  • 1
    Electronic Resource
    Electronic Resource
    Unusual complications caused by endo-clip migration following a laparoscopic cholecystectomy: Report of a case (1994)
    Springer
    Surgery today 24 (1994), S. 360-362 
    Details
    ISSN: 1436-2813
    Keywords: laparoscopic cholecystectomy ; endo-clip migration ; choledochoduodenal fistual ; obstructive jaundice
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We present herein the case of a woman who developed unexpected complications following a laparoscopic cholecystectomy. The clinical manifestations were unique in that symptoms of obstructive jaundice were in fact caused by endo-clips which had migrated into the common bile duct, and the resulting choledochoduodenal fistula presented as persistant cholangitis. While the overall safety of this new procedure appears to be superior to that of open cholecystectomy, the risk of bile duct injury seems more likely. This case stresses the need for caution by surgeons, and emphasizes the necessity for careful surveillance and strict follow-up to ensure the safety of this procedure.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02348568
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  • 2
    Electronic Resource
    Electronic Resource
    Histological Evaluation of the Effects of Intraarterial Chemotherapy for Advanced Breast Cancer: A Long-term Followup Study with Respect to the Survival Rate (1998)
    Springer
    Surgery today 28 (1998), S. 509-516 
    Details
    ISSN: 1436-2813
    Keywords: Key Words: intraarterial chemotherapy ; breast cancer ; histological response
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s005950050175
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  • 3
    Electronic Resource
    Electronic Resource
    Bruchid resistance of transgenic azuki bean expressing seed α-amylase inibitor of common bean (1996)
    Springer
    Entomologia experimentalis et applicata 79 (1996), S. 309-315 
    Details
    ISSN: 1570-7458
    Keywords: insect resistance ; genetic engineering ; host specificity ; transgenic plant ; α-amylase inhibitor ; Callosobruchus spp. ; Zabrotes subfasciatus
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Various species of bruchid beetles including Callosobruchus chinensis, C. maculatus and C. analis cause postharvest damage of azuki bean seeds, an important East Asian grain legume. The α-amylase in the midguts of these insects is inhibited by the α-amylase inhibitor (αAI) present in common bean seeds. Transformation of azuki bean with the αAI gene driven by the promoter of phytohemagglutinin results in high levels of αAI in the seeds and the complete block of bruchid development on the seeds. Zabrotes subfasciatus, a South and Central American bruchid that is a storage pest of common bean, develops normally on the transgenic azuki bean.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00186289
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  • 4
    Electronic Resource
    Electronic Resource
    Integrated Optic Pressure Sensor Using Intermodal Interference between Two Mutual Orthogonal Guided-Modes (2000)
    Springer
    Optical review 7 (2000), S. 144-148 
    Details
    ISSN: 1349-9432
    Keywords: integrated optics ; pressure sensor ; intermodal interference ; glass waveguide ; diaphragm
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract We theoretically and experimentally investigated fundamental characteristics of an integrated optic pressure sensor using intermodal interference between the lowest-order TM-like and TE-like modes. The sensor consists of a rectangular diaphragm and a straight single-mode waveguide along an edge of the diaphragm. Its operation is based on a difference of phase retardations produced in the two guided modes through the photoelastic effect. The sensor was fabricated by bonding two glass substrates together: a Corning 0211 glass 300 μMm thick to form a waveguide and a thick substrate with a 10 mm × 10 mm square hole to define the diaphragm. The fabricated sensor was successfully tested using a He-Ne laser at 633 nm. The halfwave pressure was measured to be 77 kPa which is almost double the theoretical estimate.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s10043-000-0144-4
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  • 5
    Electronic Resource
    Electronic Resource
    Pathological changes of the lungs after prolonged inhalation of high concentrations of oxygen (1986)
    Springer
    Virchows Archiv 408 (1986), S. 461-474 
    Details
    ISSN: 1432-2307
    Keywords: Pulmonary fibrosis ; Oxygen toxicity ; Respirator ; Reticulin fiber
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The pathological changes in the lungs of six patients who were treated by an artificial ventilation with a Bird or Bennett type respirator for three days to six months with oxygen concentrations of 24–100% were examined by light microscopy, studies on thick-sections, reconstruction models and vascular casts, and morphometric methods. After prolonged inhalation of high concentrations of oxygen the lungs showed thickening of the alveolar wall, marked deposition of reticulin fibers and fibroblastic proliferation in the alveolar wall, reduction in the number of capillaries, an abnormal configuration of the capillary network and hyperplasia of alveolar lining cells. These lesions are not specific to this condition, and seemed to be less marked than similar lesions in cases of chronic forms of fibrosing alveolitis, chronic interstitial pneumonia, usual interstitial pneumonia and so-called pulmonary fibrosis. Morphometric results confirm these histological observations and show not only the concentrations of oxygen but also the duration of high and pure oxygen inhalation have important roles for these pulmonary lesions. The main reasons for these lesions seemed to be repeated damage to the capillaries and loss of the normal configuration of the capillary network, accompanied by rearrangement and reconstruction of the two types of reticulin fibers.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00705300
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  • 6
    Electronic Resource
    Electronic Resource
    Genetic interaction between homoeotic Sex combs reduced and Regulator of bithorax (or trithorax) genes of Drosophila melanogaster (1988)
    Springer
    Development genes and evolution 197 (1988), S. 435-440 
    Details
    ISSN: 1432-041X
    Keywords: Drosophila ; Homoeotic genes ; Segment differentiation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary Regulator of bithorax (Rg-bx)−, or trithorax (trx)− lethal larvae occasionally show a homoeotic transformation of the dorsal prothorax to mesothoracic structures. This transformation suggests a reduced activity of the Sex combs reduced (Scr) gene on the basis of gene dosage studies, as well as enhanced expression of the phenotypes of the weak Scr − alleles in Rg-bx − larvae. Morphological observations of adult flies doubly heterozygous for Rg-bx and Scr mutations also suggest the enhancement of an aspect of Scr adult phenotypes. I conclude that the Rg-bx + gene function is required for the optimal expression of the Scr gene in larval and imaginai cells.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00398995
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  • 7
    Electronic Resource
    Electronic Resource
    Posterior interosseous nerve palsy caused by parosteal lipoma of proximal radius (1998)
    Springer
    Skeletal radiology 27 (1998), S. 375-379 
    Details
    ISSN: 1432-2161
    Keywords: Key words Parosteal lipoma ; Nerve palsy ; CT ; MRI
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  Lipomas are common benign soft tissue tumors which tend to be indolent, and symptoms caused by nerve compression are unusual. However, a parosteal lipoma, occurring adjacent to the proximal radius may easily cause paralysis of the posterior interosseous nerve because of a specific anatomical relationship of these structures in that area. Two cases of parosteal lipoma of the proximal radius causing paralysis of the posterior interosseous nerve are reported. CT and MR imaging demonstrate the characteristic fatty mass around the radius and are specific in making the diagnosis. Surgical excision should be promptly performed to ensure optimal recovery from the nerve paralysis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002560050401
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  • 8
    Electronic Resource
    Electronic Resource
    Heat shock-mediated transient increase in intracellular 3′, 5′-cyclic AMP results in tumor specific suppression of membrane type 1-matrix metalloproteinase production and progelatinase A activation (2000)
    Springer
    Clinical & experimental metastasis 18 (2000), S. 131-138 
    Details
    ISSN: 1573-7276
    Keywords: cAMP ; gelatinase A ; heat shock ; human fibroblasts ; human fibrosarcoma cells ; MT1-MMP ; tumor invasion
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We have previously reported that heat shock suppresses the production and gene expression of membrane type 1-matrix metalloproteinase (MT1-MMP) and thereby inhibits the activation of progelatinase A/proMMP-2 in human fibrosarcoma HT-1080 cells and human squamous carcinoma A431 cells and SAS cells (Sato et al. Biochem Biophys Res Commun 1999; 265: 189–93). In an effort to clarify the heat shock-mediated signal transduction pathways, an intracellular cAMP level was found to be transiently augmented in the heat shocked HT-1080 cells. When HT-1080 cells were pretreated with cAMP elevating reagents, forskolin and dibutyryl cAMP for 4 h instead of heat shock and then maintained in a fresh medium, the production and gene expression of MT1-MMP were similarly suppressed. The MT1-MMP-mediated activation of proMMP-2 was also inhibited in the forskolin- and dibutyryl cAMP-treated HT-1080 cells. Furthermore, the transiently augmented cAMP by forskolin as well as heat shock interfered with in vitro invasive activity of HT-1080 cells. In contrast, in normal human fibroblasts neither heat shock nor cAMP elevating reagents altered the concanavalin A-augmented MT1-MMP production and proMMP-2 activation. These results suggest that a transient increase in intracellular cAMP is a critical signal for heat shock to induce tumor specific-suppression of MT1-MMP production and proMMP-2 activation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1006760021997
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  • 9
    Electronic Resource
    Electronic Resource
    A computational procedure for joining separate map sheets (2000)
    Springer
    GeoJournal 52 (2000), S. 253-262 
    Details
    ISSN: 1572-9893
    Keywords: map sheets ; GIS ; seamless spatial database ; transformation ; computational procedure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geography
    Notes: Abstract Map sheets have been often used as a basic spatial unit for managing spatial data produced from paper maps. This often results in incompatibility between adjacent map sheets, because spatial objects do not cross the boundaries smoothly and even the boundaries themselves do not match their neighbors exactly. To solve the problem this paper proposes a computational procedure for joining separate map sheets to obtain seamless spatial data. Line objects digitized separately in different map sheets are considered, which are frequently used to represent road networks, gas pipelines, and boundaries of polygon objects. The procedure consists of three steps: (1) extraction of end nodes, (2) detection of matching nodes, and (3) transformation of the map sheet. Each step goes interactively so that unexpected errors can be avoided by human observation. To test the validity of the procedure, map sheets are combined containing the road network data of Tokyo 23-ku area, Japan.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1014224325346
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  • 10
    Electronic Resource
    Electronic Resource
    Identification of a binding region on Escherichia coli heat-stable enterotoxin to intestinal guanylyl cyclase C (1997)
    Springer
    International journal of peptide research and therapeutics 4 (1997), S. 1-11 
    Details
    ISSN: 1573-3904
    Keywords: Photoaffinity labeling ; Cross-linking ; p-Azidophenylalanine
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract The heat-stable enterotoxin (ST), produced by Escherichia coli, causes acute diarrhea in infants and domestic animals by activation of the intestinal membrane-bound receptor, guanylyl cyclase C. We have investigated a region on the ST molecule, which is recognized by the receptor, by introducing a photochromophore, p-azidophenylalanine (Pap), into three different regions of STp(4–17), which has the full toxic activity. Each ST analog bound to the receptor, but only STp(4–17) containing a Pap residue at position 11 in the central portion of the ST molecule, showed a high efficiency in the reaction which cross- linked with the receptor by UV radiation. These data clearly demonstrate that the region of the ST molecule encompassing the Asn11 residue directly interacts with the receptor.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1008846030577
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