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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Archives of orthopaedic and trauma surgery 65 (1969), S. 293-312 
    ISSN: 1434-3916
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé C'est le résultat de l'examen medical clinique et des radiogrammes des dysplasia des hanches qui sont soignées fontionellement: 1. L'antetorsion est plus grand plus plain est le rebord antérieur de l'acetabulum. C'est aussi le résultat des expériences avec des animaux (Idelberger, 1966). 2. Les angles de l'antetorsion et de CCD sont plus grand plus escarpés est le rebord anatomique de l'acetabulum. 3. L'angle CE était choisi comme l'index résumant pour le développement incomplet de l'acetabulum et la latéralisation et c'est pourquoi comme la mesure radiologique pour l'instabilité de l'articulation de la hanche. Les angles AT et CCD sont plus grands plus petit est l'angle CE. 4. Les angles AT et CCD sont conforms. En outre la question était discutée si le traitement par le bandage de Pavlik et par la fixation raide dans la position de Lorenz ou Lange peuvent influencer la torsion de la fin coxale du femur. Les résultats indiquent que l'antetorsion pathologique n'est pas au premier part de l'image pathologique et anatomique de la dysplasia de la hanche mais est une developpement secondaire des conditions changées quant à la statique et dynamique. C'est aussi le résultat des experiences avec des animaux (Idelberger, 1966).
    Abstract: Zusammenfassung Bei der klinischen und röntgenologischen Nachuntersuchung funktionell behandelter Hüftdysplasien ließ sich folgendes zeigen: 1. Die AT ist um so größer, je flacher der vordere Pfannenrand ist. Dies entspricht den Ergebnissen der Tierversuche Idelbergers (1966). 2. Antetorsions- und Schenkelhalswinkel sind um so größer, je steiler das anatomische Pfannendach ist (Idelberger u. Frank, 1952). 3. Der CE-Winkel (Wiberg, 1939, 1944, 1953) wurde als zusammenfassender Index für die mangelnde Pfannendachentwicklung und die Lateralisation und damit als röntgenologisches Maß für die Instabilität des Hüftgelenkes gewählt. Daher sind Antetorsions- und Schenkelhalswinkel in der Regel um so größer, je kleiner der CE-Winkel ist. 4. Antetorsions- und Schenkelhalswinkel verhalten sich bei den untersuchten Dysplasiehüften im wesentlichen gleichsinnig. Weiterhin wurde die Frage erörtert, inwieweit die Pavlik-Bandage und die starre Fixierung in Lorenz- oder Lange-Stellung die Torsion des coxalen Femurendes beeinflussen könnte. Die Ergebnisse sprechen dafür, daß die pathologische Antetorsion nicht primär endogen zum pathologisch-anatomischen Bild der Hüftdysplasie gehört, sondern sekundär Folge der veränderten statisch-dynamischen Verhältnisse des Hüftgelenkes ist.
    Notes: Summary During the clinical and X-ray examination of functionally treated cases of dislocation of the hip joint we could show the following: 1. The AT is greater, the flatter the front edge of the socket. This is corresponding to the results obtained by Idelberger in animals (1966). 2. The antetorsion angle and the angle subtended by the femoral neck to the shaft are greater, the steeper the anatomical roof of the socket (Idelberger and Frank, 1952). 3. The CE-angle (Wiberg, 1938, 1944, 1953) was chosen as a summarizing measure for the lacking development of the roof of the socket and for the lateralisation, hence as a measure of the instability of the hip joint. Accordingly, the antetorsion angle and the angle subtended by the femoral neck to the shaft are in the rule the greater, the smaller the CE-angle. 4. The antetorsion-angle and the angle subtended by the femoral neck to the shaft have in the examined cases in general the same tendency. It was further discussed which influence the Pavlik-Bandage and the stiff fixation in Lorenz- or Lange-Position have on the torsion of the coxal end of the femur. The results support the thesis that the pathological antetorsion does not belong primarily endogen to the pathologic anatomical picture of the dislocation of the hip joint, but is a socondary consequence of the changed static-dynamic conditions of the hip joint. This is corresponding to the results obtained by Idelberger in animals (1966).
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 2 (1946), S. 191-192 
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The action of desoxycorticosteronglucoside was tested on the isolated frog-heart. In concentrations of 10−6 to 10−4 a small negative inotropic effect is prevailing. Acting together with acetylcholine, the substance diminishes or abolishes the negative inotropic and chronotropic action of acetylcholine. Eserin has no influence and the inhibition is also observed with cholinchloride and the carbaminoyl ester of choline. This inhibitory action bears a close resemblance to the inhibitory action of thiamin. In both cases a complex mechanism seems to be involved.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 11 (1955), S. 67-68 
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary In the adrenalectomized and unilaterally nephrectomized rat an investigation has been carried out on the influence of a four weeks' treatment with aldosterone and desoxycorticosterone-acetate in doses which are equieffective concerning sodium retaining capacity. Desoxycorticosterone-acetate produced hypertension, perivascular granuloma and renal lesions, whereas under the influence of aldosterone the blood pressure remained normal and no histopathological alterations could be found. Towards the end of the experiment the animals treated with desoxycorticosterone-acetate took up twice as much drinking fluid as the animals treated with aldosterone. Although the results obtained so far are only of a preliminary character it is obvious that aldosterone in doses which are equieffective concerning sodium retention does not produce the same side effects as desoxycorticosterone-acetate.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 13 (1957), S. 401-403 
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary A number of basically substituted benzimidazoles show a strong analgesic activity in mice, rats, rabbits, and dogs. Qualitatively they act very similarly to morphine and corresponding synthetic analgetics and the most active of these compounds are quantitatively superior to all analgetics hitherto described.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 17 (1961), S. 192-192 
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 35 (1979), S. 1113-1115 
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary High-titer antibodies against bradykinin were raised in rabbits. 2 different conjugates of bradykinin were used for immunization: bradykinin coupled to human serum albumin via 1,5-difluoro-2,4-dinitrobenzene and bradykinin coupled to edestin via 1-ethyl-3(3-dimethyl-aminopropyl)-carbodiimide. The sensitivity of the radioimmunoassay method is in the range of 1–50 pg of bradykinin. Cross-reaction of anti-bradykinin antisera occurred with kallidin and met-lysbradykinin.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 36 (1980), S. 865-866 
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Rat urine, even at a 1∶10 final dilution in Tyrode's solution, stimulates contraction of the ureteral musculature in vitro. This effect can be ascribed to the presence of kallikrein or a kallikrein-like enzyme in urine. Isometric contractions of ureters were prevented by previous addition of aprotinin to the organ bath. Urine also lost its activity after inactivation of enzymes by heat or acid treatment.
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 33 (1977), S. 333-335 
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary After injection of microspheres into both renal arteries of rats, an irreversible shock syndrome develops, resulting in death within 4–12 h. Ligation of both renal pedicles after injection of microspheres prevents the shock. It is presumed that kininogenases released from the kidneys participate in the pathogenesis of the shock syndrome.
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 38 (1960), S. 862-866 
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary 1. A standard colorimetric method for the estimation of sulphaphenazol was compared with one using a radio-isotope technique in which the sulphonamide was labelled with35S. Both methods gave very similar values for the concentrations in blood and also in plasma in the animal species investigated. 2. Good agreement was found between the values given by both methods for urinary and faecal elimination following intravenous as well as oral administration of sulphaphenazol. 3. In the various organs investigated, however, the radiochemical method gave much higher concentrations than the colorimetric method, especially during the first 24 hours after the administration of the sulfonamide. In the lung a relatively high activity was measurable for a longer period than in the other organs, but it cannot be decided whether this was due to the unchanged sulphonamide or to degradation products. 4. The results confirm the experimental and clinical observations that sulfaphenazol belongs to the group of sulphonamides which do not depend for their long duration of action on excessively high blood concentrations or unduly delayed excretion.
    Notes: Zusammenfassung 1. Vergleichende Untersuchungen mit der colorimetrischen Bestimmung und einer radiochemischen Methode, mit der35S markiertes Sulfonamid nachgewiesen wird, ergaben am Beispiel des Sulfaphenazol (Orisul) eine weitgehende Übereinstimmung der Blut- und Plasmakonzentrationen bei verschiedenen Tierarten. 2. Auch für die Ausscheidung im Urin und Kot zeigten die beiden Methoden gut übereinstimmende Werte, und zwar sowohl bei intravenöser als auch bei peroraler Gabe. 3. In den untersuchten Organen fanden sich dagegen mit der radiochemischen Methode wesentlich höhere Werte als mit der colorimetrischen, und zwar besonders innerhalb der ersten 24 Std nach Gabe des Präparates. In der Lunge war eine relativ hohe Radioaktivität länger nachweisbar als in den anderen Organen, wobei aber nicht feststeht, ob diese auf unverändertes Sulfonamid oder ein Abbauprodukt zurückzuführen ist. 4. Die erhobenen Befunde bestätigen die experimentellen und klinischen Beobachtungen, nach denen Sulfaphenazol zu den langwirkenden Sulfaderivaten zu rechnen ist, ohne daß es zu „überhöhten“ Blutkonzentrationen oder verzögerter Ausscheidung führt.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 34 (1956), S. 929-941 
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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