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  • 1
    Electronic Resource
    Electronic Resource
    Atrioventricular Node Reentrant Tachycardia in Patients With a Prolonged AH Interval During Sinus Rhythm: Clinical Features, Electrophysiologic Characteristics and Results of Radiofrequency Ablation (1997)
    Springer
    Journal of interventional cardiac electrophysiology 1 (1997), S. 305-310 
    Details
    ISSN: 1572-8595
    Keywords: atrioventricular node reentrant tachycardia ; radiofrequency ablation ; AH interval
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Among a consecutive series of 600 patients who underwent radiofrequency catheter ablation for AV node reentrant tachycardia, 14 patients (age 29-76 years) had a prolonged AH interval during sinus rhythm (172±18 ms, range 140 to 200). Seven of them had unsuccessful ablation during the previous ablation sessions. Eight patients with anterograde dual AV node pathway physiology received anterograde slow pathway ablation, and the other 6 patients without dual-pathway physiology received retrograde fast pathway ablation. All patients had successful elimination of AV nodal reentrant tachycardia after a mean of 4±4 radiofrequency applications, power level 36±6 watts and a pulse duration of 42±4 seconds. The postablation AH interval remained unchanged. During a follow-up period of 25±13 months, one patient who received slow pathway ablation developed 2:1 AV block with syncope. As compared with the other 586 patients without a prolonged AH interval, these 14 patients had significantly poorer anterograde AV nodal function and lower incidence of anterograde dual AV node physiology (P〈0.01). We concluded that slow pathway ablation in patients with dual pathway physiology, and retrograde fast pathway ablation in patients without dual pathway physiology were effective and safe in patients with a prolonged AH interval. However, delayed onset of symptomatic AV block is possible and careful follow-up is necessary.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1009785127119
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  • 2
    Electronic Resource
    Electronic Resource
    Identification of Fiber Orientation in Left Free-Wall Accessory Pathways: Implication for Radiofrequency Ablation (1997)
    Springer
    Journal of interventional cardiac electrophysiology 1 (1997), S. 235-241 
    Details
    ISSN: 1572-8595
    Keywords: fiber orientation ; accessory pathway ; radiofrequency ablation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Previous reports on the anatomic discordance between atrial andventricular insertion sites of left free-wall accessory pathways werelimited and their findings were controversial. The purpose of this studywas to explore the fiber orientation and related electrophysiologiccharacteristics of left free-wall accessory pathways. The study populationcomprised 96 consecutive patients with a single left free-wall accessorypathway (33 manifest and 63 concealed pathways), who underwentelectrophysiologic study and radiofrequency catheter ablation using theretrograde ventricular approach. The atrial insertion site of the accessorypathway was defined from the cinefilms as the site with the earliestretrograde atrial activation bracketed on the coronary sinus catheterduring tachycardia, and the ventricular insertion site was defined as thesite where successful ablation of the pathway was achieved. Forty-twopatients (44%) had their atrial insertion sites 5-20 mm (10 ±3 mm) distal to the ventricular insertion sites (proximal excursion), 30(31%) patients had their atrial insertion sites 5-20 mm (12 ±3 mm) proximal to the ventricular insertion sites (distal excursion), and24 (25%) patients had directly aligned atrial and ventricular insertion sites. Retrograde conduction properties, including 1:1 VA conduction and effective refractory period, were significantly poorer inthe pathways with proximal excursion (302 ± 67, 285 ± 61 msrespectively) than in those with distal excursion (264 ± 56, 250± 48 ms respectively) or direct alignment (272 ± 61, 258± 73 ms respectively). Accessory pathways at the more posteriorlocation had a significantly higher incidence of proximal excursion (P= 0.006), and those at the more anterior location had a higherincidence of distal excursion (P = 0.012). In conclusion, a widevariation in fiber orientations and related electrophysiologic characteristics was found in left free-wall accessory pathways. This mayhave important clinical implications for radiofrequency ablation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1009773007803
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  • 3
    Electronic Resource
    Electronic Resource
    Electrophysiologic Characteristics of Different Ectopic Rhythms During Slow Pathway Ablation in Patients with Atrioventricular Nodal Reentrant Tachycardia (1998)
    Springer
    Journal of interventional cardiac electrophysiology 2 (1998), S. 203-209 
    Details
    ISSN: 1572-8595
    Keywords: slow pathway ; AV node ; catheter ablation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The presence of ectopic rhythm has been considered to be the most important marker for successful slow pathway ablation, but the details of different ectopic rhythms have not been well described. This study included 83 consecutive patients with typical AV node reentrant tachycardia who underwent slow pathway ablation. The interval between the atrial signals of the His bundle electrogram and the distal ablation catheter [A(H)-A(Ab)], and the interval between the atrial components of the distal ablation catheter and the ostium of coronary sinus catheter [A(Ab)-A(CSos)] were measured. One hundred episodes of ectopic rhythm occurred with 81 (81%) successful applications. There are two different origins and three activation sequences of ectopic rhythms, including HIS rhythm (78 applications, the earliest atrial activation in the His bundle electrogram), CSos rhythm (6 applications, the earliest atrial signal in the coronary sinus ostium electrogram) and CSos preceding HIS (CSos→HIS) rhythm (16 applications, the atrial activation sequences changing from CSos to HIS rhythm). The CSos rhythm had a shorter mean cycle length (445 ± 81 vs. 511 ± 132 vs. 579 ± 140 ms, p 〈 0.05), a shorter [A(Ab)-A(CSos)] interval (−2.5 ± 9.8 vs. 14.1 ± 11.2 vs. 12.8 ± 8.4 ms, p 〈 0.05) and a lower success rate (33% vs. 84% vs. 94% p 〈 0.05) than HIS rhythm and CSos→HIS rhythm. Otherwise, the mean cycle length of ectopic rhythm was significant shorter in successful than in failed ablation (506 ± 135 vs. 559 ± 118 ms, p = 0.04). In conclusion, we found two different origins and three activation sequences of ectopic rhythms. CSos rhythm had a lower success rate in ablation of slow pathway, thus it was a poor marker for successful ablation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1009715919068
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  • 4
    Electronic Resource
    Electronic Resource
    Electrophysiologic Characteristics of a Dilated Atrium in Patients with Paroxysmal Atrial Fibrillation and Atrial Flutter (1998)
    Springer
    Journal of interventional cardiac electrophysiology 2 (1998), S. 181-186 
    Details
    ISSN: 1572-8595
    Keywords: atrial enlargement ; atrial fibrillation ; atrial flutter ; electrophysiology
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract This study investigated the difference of atrial electrophysiologic characteristics between a normal and dilated atrium and compared them among patients with paroxysmal atrial fibrillation and flutter. Twenty-seven patients with paroxysmal atrial fibrillation and 28 patients with paroxysmal atrial flutter were divided into four subgroups, according to the presence of a normal atrium or bilateral atrial enlargement. Thirty patients without atrial arrhythmia (20 patients with normal atrium and 10 patients with bilateral atrial enlargement) were included in control group. The atrial refractoriness in patients with a dilated atrium was longer than those with normal atrial size. In patients with paroxysmal atrial fibrillation and patients of control group, the P-wave duration and interatrial conduction velocity with or without atrial enlargement were similar. However, in patients with paroxysmal atrial flutter, P-APCS (86 ± 10 ms vs. 73 ± 9 ms, p 〈 0.05) and P-ADCS (109 ± 9 ms vs. 95 ± 9 ms, p 〈 0.05) in patients with a dilated atrium were longer than in patients with a normal atrium. The patients with paroxysmal atrial fibrillation or atrial flutter all demonstrated longer P-wave duration and interatrial conduction time than control group. Among the groups with a normal atrium or a dilated atrium, atrial refractoriness in patients with paroxysmal atrial flutter was shorter than that in control group. Moreover, in the patients with a normal atrium, the potential minimal wavelength in control group (6.6 ± 1.7) was longer than that of paroxysmal atrial fibrillation (5.3 ± 1.1), or atrial flutter (5.0 ± 1.2). These findings suggest that atrial electrophysiologic characteristics of a dilated atrium were different from those of normal atrium, and these changes were different between paroxysmal atrial fibrillation and flutter. Multiple factors are considered to be related to the genesis of atrial tachyarrhythmias.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1009759717250
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  • 5
    Electronic Resource
    Electronic Resource
    Editorial Comment: Can We Avoid Pulmonary Vein Stenosis Following Ablation of Atrial Fibrillation? (2000)
    Springer
    Journal of interventional cardiac electrophysiology 4 (2000), S. 633-634 
    Details
    ISSN: 1572-8595
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1026525901853
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  • 6
    Electronic Resource
    Electronic Resource
    No evidence for linkage of long QT syndrome and chromosome 11p15.5 markers in a Chinese family: evidence for genetic heterogeneity (1994)
    Springer
    Human genetics 〈Berlin〉 94 (1994), S. 364-366 
    Details
    ISSN: 1432-1203
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Recently the defective gene locus in seven Caucasian families with the Romano-Ward form of long QT syndrome (LQT) has been mapped to chromosome 11p. To understand the molecular basis of LQT in Chinese, a three-generation family was investigated. Fourteen family members were studied and five individuals were diagnosed to be affected, according to electrocardiographic criteria. Two genomic DNA probes (c-Ha-ras-3′-HVR and insulin-5′-HVR) and one tetranucleotide repeat polymorphism (THZ) derived from chromosome 11p15.5 loci and previously demonstrated to be closely linked to LQT were used as probes to analyze this family. A lod score of less than -2 was noted for all three polymorphisms. Our data show that there was no evidence of linkage between these three loci and the gene for LQT in this studied family. We believe that this result provides additional evidence for genetic heterogeneity of LQT.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00201594
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  • 7
    Electronic Resource
    Electronic Resource
    Proarrhythmic Activity and Interactions of Non-Cardiac Drugs and Other Substances (1998)
    Springer
    Cardiac electrophysiology review 2 (1998), S. 147-150 
    Details
    ISSN: 1573-725X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1009919530781
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