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  • 1
    Online Resource
    Online Resource
    Comparative Study of Analgesic Efficacy of Ultrasound Guided Femoral Nerve Block versus Intravenous Fentanyl Injection in Fracture Femur Patients at Emergency Department
    Sciencedomain International ; 2022
    In:  Journal of Advances in Medicine and Medical Research ( 2022-05-02), p. 45-53
    Details
    In: Journal of Advances in Medicine and Medical Research, Sciencedomain International, ( 2022-05-02), p. 45-53
    Abstract: Aim: The aim of this work was to evaluate the analgesic efficacy of ultrasound guided femoral nerve block compared with intravenous (IV) fentanyl in fractures of the femur in patients presented to Emergency Department (ED). Methods: This prospective, comparative, (blinded, randomized controlled clinical trial) was conducted on fifty patients with femur fracture. Patients were divided into two equal groups: group A underwent ultrasonography-guided femoral nerve block and group B given IV fentanyl 2 µg/kg). All patients underwent initial resuscitation. Intra-venous (IV) access with wide bore cannula and baseline investigation were obtained. Patients underwent X-ray imaging for diagnosis of femur fracture and FAST (Focused Assessment with Sonography for Trauma) scan on presentation at ED by ED trained physicians. Results: There is significant difference in group B as regard to peripheral oxygen saturation (SpO2) and Systolic blood pressure (P 〈 0.001 and 0.013 respectively).  VAS (median ± SD) was lesser in group A 4.16 ± 2.12 VS 4.96 ± 2.05 in group B. Pain intensity difference was significant decrease group A over time (P= 0.032). Requesting analgesia and rescue analgesia were insignificant different between two groups. Conclusions: Both femoral nerve block and IV fentanyl are effective in relieving pain in patients with femur fractures. But femoral nerve block provides better and intense analgesia, and major pain intensity difference in less time. Moreover, use of FNB had fewer side effects and more hemodynamicsstability as compared to opioids.
    Type of Medium: Online Resource
    ISSN: 2456-8899
    URL: Article
    DOI: 10.9734/jammr/2022/v34i1331378
    Language: Unknown
    Publisher: Sciencedomain International
    Publication Date: 2022
    detail.hit.zdb_id: 3166828-8
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  • 2
    Online Resource
    Online Resource
    Prognostic Value of Urine Albumen/Creatinin Ratio in Sepsis in Critical Care Patients
    Sciencedomain International ; 2019
    In:  Journal of Advances in Medicine and Medical Research ( 2019-04-12), p. 1-16
    Details
    In: Journal of Advances in Medicine and Medical Research, Sciencedomain International, ( 2019-04-12), p. 1-16
    Abstract: Several scoring systems were developed for prognosis and outcome prediction in sepsis. This study aims to evaluate the urinary albumin/creatinine ratio (ACR) as a prognostic predictor in sepsis. The study included 50 adult septic patients in a prospective observational study. Study excluded patients with preexisting chronic kidney disease or diabetes mellitus. After clinical evaluation, urine spot samples were collected on admission and 24 h later for ACR1 and ACR2. Admission APACHE IV score and the highest recorded SOFA score of their daily estimation were considered. This study also evaluated the need for mechanical ventilation, inotropic or vasoactive support, renal replacement therapy (RRT), and in-hospital mortality. In a population with Mean±SD 51.4±16.3 (19-82) year old with 34 (68%) males, we found that the ACR2 is correlated with both APACHE IV and SOFA scores (P 〈 0.001). ACR2 was higher in patients who needed mechanical ventilation and inotropic or vasoactive support [121(21-235) and 166.5(89-235) mg/g respectively] compared to [49(22-120) and 56.5(21-211) mg/g] , P 〈 0.001 in both. ΔACR, ACR2, increasing ACR and APACHE IV were predictors of mortality. The AUC for mortality prediction was largest for ΔACR (1), increasing ACR (0.985), ACR2 (0.963) then APACHE IV (0.90). ∆ACR and ACR2 of 91.5 mg/g and -22 was 88.2% & 100% sensitive and 90.9% & 100% specific respectively to predict mortality. We concluded that the urinary ACR might be used as a simple test for prognosis and mortality prediction in sepsis.
    Type of Medium: Online Resource
    ISSN: 2456-8899
    URL: Article
    DOI: 10.9734/jammr/2019/v29i630098
    Language: Unknown
    Publisher: Sciencedomain International
    Publication Date: 2019
    detail.hit.zdb_id: 3166828-8
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  • 3
    Online Resource
    Online Resource
    Prognostic Value of Urine Albumen/Creatinin Ratio in Sepsis in Critical Care Patients
    Sciencedomain International ; 2019
    In:  Journal of Advances in Medicine and Medical Research ( 2019-04-12), p. 1-16
    Details
    In: Journal of Advances in Medicine and Medical Research, Sciencedomain International, ( 2019-04-12), p. 1-16
    Abstract: Several scoring systems were developed for prognosis and outcome prediction in sepsis. This study aims to evaluate the urinary albumin/creatinine ratio (ACR) as a prognostic predictor in sepsis. The study included 50 adult septic patients in a prospective observational study. Study excluded patients with preexisting chronic kidney disease or diabetes mellitus. After clinical evaluation, urine spot samples were collected on admission and 24 h later for ACR1 and ACR2. Admission APACHE IV score and the highest recorded SOFA score of their daily estimation were considered. This study also evaluated the need for mechanical ventilation, inotropic or vasoactive support, renal replacement therapy (RRT), and in-hospital mortality. In a population with Mean±SD 51.4±16.3 (19-82) year old with 34 (68%) males, we found that the ACR2 is correlated with both APACHE IV and SOFA scores (P 〈 0.001). ACR2 was higher in patients who needed mechanical ventilation and inotropic or vasoactive support [121(21-235) and 166.5(89-235) mg/g respectively] compared to [49(22-120) and 56.5(21-211) mg/g] , P 〈 0.001 in both. ΔACR, ACR2, increasing ACR and APACHE IV were predictors of mortality. The AUC for mortality prediction was largest for ΔACR (1), increasing ACR (0.985), ACR2 (0.963) then APACHE IV (0.90). ∆ACR and ACR2 of 91.5 mg/g and -22 was 88.2% & 100% sensitive and 90.9% & 100% specific respectively to predict mortality. We concluded that the urinary ACR might be used as a simple test for prognosis and mortality prediction in sepsis.
    Type of Medium: Online Resource
    ISSN: 2456-8899
    URL: Article
    DOI: 10.9734/jammr/2019/v29i630119
    Language: Unknown
    Publisher: Sciencedomain International
    Publication Date: 2019
    detail.hit.zdb_id: 3166828-8
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  • 4
    Online Resource
    Online Resource
    Diagnostic and Prognostic Role of Plasma Osteopontin Levels in Children with Pulmonary Hypertension Associated with Congenital Heart Disease at Tanta University Hospitals
    Sciencedomain International ; 2022
    In:  Journal of Advances in Medicine and Medical Research ( 2022-10-14), p. 365-374
    Details
    In: Journal of Advances in Medicine and Medical Research, Sciencedomain International, ( 2022-10-14), p. 365-374
    Abstract: Background: Natural progression of CHD often results in the development of pulmonary arterial hypertension (PAH), which is a leading cause of death and disability. Aim: The goal of this work is to clarify the prognostic and diagnostic usefulness of OPN in children with PAH-CHD, as well as to determine whether or not its level correlates with clinical and echocardiographic data of PAH-CHD. Methodology: Fifty CHD children and twenty-five healthy children served as a control subject in this research. Plasma OPN levels were measured using ELISA kits after a thorough medical history, physical examination, and series of tests (radiological, laboratory, and diagnostic). Place and Duration of Study: Patients were chosen from those hospitalised to the Tanta University Hospital Pediatric Cardiology Unit, Pediatric Department, between April 2021 and April 2022. Results: There was significant increase of plasma OPN levels in PAH- CHD patients as compared to CHD patients without PH as compared to control group. OPN levels was also found to be positively correlated with age, disease severity, mPAP and RV diameter and negatively correlated with RV E/A ratio. OPN can be used as a diagnostic biomarker with sensitivity 92% and specificity 96% and as a prognostic biomarker with sensitivity 86% and specificity 90%. Conclusion: Plasma levels of OPN were significantly elevated in PAH-CHD children, and these levels were correlated to the severity of PH and echocardiographic parameters. OPN levels were markedly elevated in PAH-CHD patients with bad prognosis.
    Type of Medium: Online Resource
    ISSN: 2456-8899
    URL: Article
    DOI: 10.9734/jammr/2022/v34i224824
    Language: Unknown
    Publisher: Sciencedomain International
    Publication Date: 2022
    detail.hit.zdb_id: 3166828-8
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  • 5
    Online Resource
    Online Resource
    Correlations of Plasma Biotinidase Levels with Hepatic Synthetic Functions in Children with Chronic Liver Diseases
    Sciencedomain International ; 2017
    In:  International Journal of Biochemistry Research & Review Vol. 16, No. 4 ( 2017-01-10), p. 1-7
    Details
    In: International Journal of Biochemistry Research & Review, Sciencedomain International, Vol. 16, No. 4 ( 2017-01-10), p. 1-7
    Type of Medium: Online Resource
    ISSN: 2231-086X
    URL: Journal
    URL: Article
    DOI: 10.9734/IJBCRR
    DOI: 10.9734/IJBCRR/2017/32764
    Language: Unknown
    Publisher: Sciencedomain International
    Publication Date: 2017
    detail.hit.zdb_id: 2617241-0
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  • 6
    Online Resource
    Online Resource
    The Influence of Smoking on Choroidal, Macular and Retinal Nerve Fiber Layer Thickness
    Sciencedomain International ; 2021
    In:  Journal of Advances in Medicine and Medical Research ( 2021-10-26), p. 46-55
    Details
    In: Journal of Advances in Medicine and Medical Research, Sciencedomain International, ( 2021-10-26), p. 46-55
    Abstract: Background: Smoking is one of the most serious health hazards because it affects every organ in our bodies. Cigarette smoking increases the chance of developing systemic and ocular vascular diseases significantly. Although the exact mechanism behind the association between ocular vascular disorders and smoking are unknown, the peripheral vasoconstriction action of nicotine is believed to lead to an increase in peripheral blood flow resistance. This study was designed to examine the impact of smoking with Spectral Domain Optical Coherence Tomography (SD-OCT) on the peripapillary retinal nerve fibre (RNFL), macular, and choroidal thickness. Methods: This prospective study was done on 50. It included 25 healthy cigarette smokers with no systemic or ocular illness and another 25 age- and gender-matched healthy non-smokers. Results: The smoking group had a substantial reduction in central macular and choroidal thickness as compared to the nonsmoker group. The RNFL peripapillary thickness across groups was not significantly altered, with the exception of the temporal (T) quadrant which was significantly thinner in the smoking group. This study discovered a substantial negative correlation between peripapillary RNFL, central macular thickness, and smoking exposure. Conclusions: Smoking reduces the mean thickness of the peripapillary retinal nerve fibre layer (particularly in the temporal quadrant), the choroidal layer, and the central macular layer statistically significantly.
    Type of Medium: Online Resource
    ISSN: 2456-8899
    URL: Article
    DOI: 10.9734/jammr/2021/v33i2131133
    Language: Unknown
    Publisher: Sciencedomain International
    Publication Date: 2021
    detail.hit.zdb_id: 3166828-8
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  • 7
    Online Resource
    Online Resource
    The Effect of Carbetocin versus Misoprostol versus Ergometrine for Controlling Bleeding after Cesarean Section in Primigravidae
    Sciencedomain International ; 2022
    In:  Journal of Advances in Medicine and Medical Research ( 2022-07-15), p. 171-177
    Details
    In: Journal of Advances in Medicine and Medical Research, Sciencedomain International, ( 2022-07-15), p. 171-177
    Abstract: Background: Women undergoing cesarean section have a high risk of blood loss and so are more likely to need a blood transfusion. The aim of this work was to compare the effectiveness of using carbetocin versus misoprostol versus ergometrine for controlling bleeding after cesarean section in primigravidae. Methods: This prospective randomized clinical trial was conducted on 150 patients aged from18-35 years old, primigravidae with singleton pregnancy undergoing elective cesarean section. Participants were divided into three equal groups: carbetocin group (group C) received a single 1-ml ampoule of carbetocin (100 μg/mL) added to 10 cm saline intravenously following the delivery of the neonate, misoprostol group (group M) received misoprostol 400ug per rectum immediately after induction of anesthesia in operating theater and ergometrine group (group E) received 0.2 mg of ergometrine intramuscularly in the first minute after delivery of the baby. Results: The amount of blood in suction jar, amount of blood loss, Hb change and HTC change were significantly higher in the misoprostol group and ergometrine group than in the carbetocin group (p 〈 0.05) and in the ergometrine group than the misoprostol group (p 〈 0.001). Post-operative Hb in the ergometrine group was significantly lower in the carbetocin group (p =0.001). Conclusions: Carbetocin can be considered a superior choice to misoprostol and ergometrine in reducing blood loss during CS in primigravidae.
    Type of Medium: Online Resource
    ISSN: 2456-8899
    URL: Article
    DOI: 10.9734/jammr/2022/v34i2031482
    Language: Unknown
    Publisher: Sciencedomain International
    Publication Date: 2022
    detail.hit.zdb_id: 3166828-8
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  • 8
    Online Resource
    Online Resource
    Study of the Gut Enterotypes in Egyptian Children with Autism Spectrum Disorder
    Sciencedomain International ; 2018
    In:  Microbiology Research Journal International Vol. 23, No. 6 ( 2018-05-17), p. 1-9
    Details
    In: Microbiology Research Journal International, Sciencedomain International, Vol. 23, No. 6 ( 2018-05-17), p. 1-9
    Type of Medium: Online Resource
    ISSN: 2456-7043
    URL: Journal
    URL: Article
    DOI: 10.9734/MRJI
    DOI: 10.9734/MRJI/2018/41460
    Language: Unknown
    Publisher: Sciencedomain International
    Publication Date: 2018
    detail.hit.zdb_id: 3166857-4
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  • 9
    Online Resource
    Online Resource
    Existence of Mild Solution for Impulsive Fractional Differential Equations with Non-local Conditions in Banach Space
    Sciencedomain International ; 2014
    In:  British Journal of Mathematics & Computer Science Vol. 4, No. 6 ( 2014-01-10), p. 830-840
    Details
    In: British Journal of Mathematics & Computer Science, Sciencedomain International, Vol. 4, No. 6 ( 2014-01-10), p. 830-840
    Type of Medium: Online Resource
    ISSN: 2231-0851
    URL: Journal
    URL: Article
    DOI: 10.9734/BJMCS
    DOI: 10.9734/BJMCS/2014/7673
    Language: Unknown
    Publisher: Sciencedomain International
    Publication Date: 2014
    detail.hit.zdb_id: 2633127-5
    detail.hit.zdb_id: 3146750-7
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  • 10
    Online Resource
    Online Resource
    Prognostic Factors for Successful Microdissection Testicular Sperm Extraction (Micro-TESE)
    Sciencedomain International ; 2021
    In:  Journal of Advances in Medicine and Medical Research ( 2021-07-13), p. 30-35
    Details
    In: Journal of Advances in Medicine and Medical Research, Sciencedomain International, ( 2021-07-13), p. 30-35
    Abstract: Background: There are some men suffer from infertility, non-obstructive azoospermia is one of the causes of infertility, these men need sperm retrieval from testes like microdissection testicular sperm extraction (Micro-TESE). This work aims to assess the different preoperative and intraoperative factors that predict successful sperm retrieval with Microdissection Testicular Sperm Extraction (Micro-TESE) in men with non-obstructive azoospermia. Methods: Our study is a cohort prospective one, conducted on 52 male patients with non-obstructive azoospermia who attended to the outpatient andrology and infertility clinic of Urology Department, Tanta University Hospitals during the period between December2018 to November2019. All patients were subjected to detailed medical history, physical examination, two semen analysis on two different laboratories. Microdissection Testicular Sperm Extraction is performed to all patients after Estimation of serum FSH, LH, testosterone, prolactin, estradiol and scrotal Doppler ultrasonography Results: From 52 patients who have done, Patients were divided in to 2 groups according to the result of Micro-TESE procedure: negative SSR group (28 patients) and positive SSR group (24 patients).In comparison between the two groups according to preoperative factors as age, FSH, LH, estradiol, testosterone, prolactin and testicular volume, there was no significant difference between these groups. On comparison of intraoperative size of seminiferous tubules in relation to results of Micro-TESE, we found that presence of large convoluted seminiferous tubules was statistically significant in prediction of successful sperm retrieval with Micro-TESE Conclusions: The chances of sperm retrieval in men with NOA by Micro-TESE are not related to preoperatively age, FSH, LH, testosterone, estradiol, prolactin and testicular volume. The detection of large seminiferous tubules intraoperatively is a good predictor for successful sperm retrieval with Micro-TESE as it was statistically significant.
    Type of Medium: Online Resource
    ISSN: 2456-8899
    URL: Article
    DOI: 10.9734/jammr/2021/v33i1630998
    Language: Unknown
    Publisher: Sciencedomain International
    Publication Date: 2021
    detail.hit.zdb_id: 3166828-8
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