In:
Ophthalmic Surgery, Lasers and Imaging Retina, SLACK, Inc., Vol. 45, No. 4 ( 2014-05-23), p. 332-334
Abstract:
Pediatric Vogt-Koyanagi-Harada syndrome (VKH) is rare, with limited cases of corticosteroid-sparing immunosuppression use reported. A 15-year-old Hispanic girl was referred for bilateral intraocular inflammation. Her initial best corrected visual acuity (BCVA) was 20/30 in the right eye and 20/200 in the left eye, with granulomatous keratic precipitates, anterior chamber and vitreous cell, optic disc edema, and nummular depigmented chorioretinal lesions on examination consistent with VKH after an unrevealing work-up. Inflammation was recurrent despite oral prednisone and methotrexate. Adalimumab, a TNF-alpha inhibitor, led to rapid resolution of inflammation, successful dose reduction of prednisone and methotrexate, and final BCVA of 20/25 in the right eye and 20/40 in the left at 26-month follow-up. [ Ophthalmic Surg Lasers Imaging Retina . 2014;45:332-333.]
Type of Medium:
Online Resource
ISSN:
2325-8160
,
2325-8179
DOI:
10.3928/23258160-20140709-09
Language:
English
Publisher:
SLACK, Inc.
Publication Date:
2014
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