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  • 1
    Online Resource
    Online Resource
    NaH-Promoted Transformation of Arylthioureas to Aryl-Isothioureas by S-Allylation and S-Benzylation Reactions
    SAGE Publications ; 2017
    In:  Journal of Chemical Research Vol. 41, No. 3 ( 2017-03), p. 165-167
    Details
    In: Journal of Chemical Research, SAGE Publications, Vol. 41, No. 3 ( 2017-03), p. 165-167
    Abstract: A series of 16 substituted aryl-isothioureas were prepared in excellent yields (80–97%) by reacting substituted arylthioureas with allyl bromide or substituted benzyl bromides in the presence of NaH in DMSO at room temperature. The substituent variations on the benzyl reactants had a larger effect on the yields than substituent variations on the allyl reactants. The method provides a facile and convenient preparation of some potentially biologically active compounds.
    Type of Medium: Online Resource
    ISSN: 1747-5198 , 2047-6507
    URL: Article
    DOI: 10.3184/174751917X14878812592733
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2017
    detail.hit.zdb_id: 3010810-X
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  • 2
    Online Resource
    Online Resource
    Tai Chi for improving cardiopulmonary function and quality of life in patients with chronic obstructive pulmonary disease: a systematic review and meta-analysis
    SAGE Publications ; 2016
    In:  Clinical Rehabilitation Vol. 30, No. 8 ( 2016-08), p. 750-764
    Details
    In: Clinical Rehabilitation, SAGE Publications, Vol. 30, No. 8 ( 2016-08), p. 750-764
    Abstract: To examine the effect of Tai Chi on cardiopulmonary function and quality of life in chronic obstructive pulmonary disease. Data sources: Cochrane Library, PUBMED, EMBASE, China Biology Medicine disc, China National Knowledge Infrastructure, and Wanfang database. Methods: Articles on randomized controlled trials comparing Tai Chi with other treatments or no treatment were identified. A random-effects model was used to calculate the pooled mean difference (MD) with 95% confidence interval (CI). Results: Fifteen articles involving 1354 participants were included. Compared with the control group, Tai Chi was more effective in improving exercise capacity on 6-minute walking distance (short term: MD = 16.02, 95% CI 2.86 to 29.17; mid term: MD = 30.90, 95% CI 6.88 to 54.93; long term: MD = 24.63, 95% CI 2.30 to 46.95), as well as pulmonary functions on forced expiratory volume in the first second (mid term: MD = 0.10; 95% CI 0.01 to 0.19), and forced vital capacity (mid term: MD = 0.20; 95% CI 0.04 to 0.36). Concerning quality of life, we found Tai Chi was better than the control group for the Chronic Respiratory Disease Questionnaire dyspnoea score (short term: MD = 0.90; 95% CI 0.51 to 1.29), fatigue score (short term: MD = 0.75; 95% CI 0.42 to 1.09), and total score (short term: MD = 1.92; 95% CI 0.54 to 3.31). Conclusions: Tai Chi may improve exercise capacity in the short, mid, and long terms. However, no significant long term differences in pulmonary function and quality of life were observed for patients with chronic obstructive pulmonary disease.
    Type of Medium: Online Resource
    ISSN: 0269-2155 , 1477-0873
    URL: Article
    DOI: 10.1177/0269215515604903
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2016
    detail.hit.zdb_id: 2028323-4
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  • 3
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    Dynamic constitutive relation of 5083P-O aluminium alloy and its influence on energy-absorbing structure
    SAGE Publications ; 2018
    In:  Advances in Mechanical Engineering Vol. 10, No. 10 ( 2018-10), p. 168781401880733-
    Details
    In: Advances in Mechanical Engineering, SAGE Publications, Vol. 10, No. 10 ( 2018-10), p. 168781401880733-
    Abstract: Dynamic and quasi-static tensile tests of 5083P-O aluminium alloy were carried out using RPL100 electronic creep/fatigue testing machine and the split Hopkinson tension bar, respectively. The dynamic constitutive relation of the material at high strain rates was studied, and the constitutive model in accordance with Cowper–Symonds form was established. At the same time, a method to describe the constitutive relation of material using the strain rate interpolation method which is included in LS-DYNA software was proposed. The advantages and accuracy of this method were verified by comparing the results of the finite element simulation with the fitting results of the Cowper-Symonds model. The influence of material strain rate effect on squeezing force, energy absorption and deformation mode of the squeezing energy-absorbing structure based on the constitutive models of 5083P-O were studied by means of finite element simulation. The results show that when the strain rate of the structure deformation is low, the material strain rate strengthening effect has little influence on the structure. However, with the increase of the strain rate, the strengthening effect of the material will improve the squeezing force and the energy absorption of the structure, and will also influence the deformation mode, that is, the decrease of the deformation with high strain rates while the increase of the deformation with low strain rates.
    Type of Medium: Online Resource
    ISSN: 1687-8140 , 1687-8140
    URL: Article
    DOI: 10.1177/1687814018807334
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2018
    detail.hit.zdb_id: 2501620-9
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  • 4
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    Comparative Proteomic Analysis of the Effect of the Four-Herb Chinese Medicine ANBP on Promoting Mouse Skin Wound Healing
    SAGE Publications ; 2017
    In:  The International Journal of Lower Extremity Wounds Vol. 16, No. 3 ( 2017-09), p. 154-162
    Details
    In: The International Journal of Lower Extremity Wounds, SAGE Publications, Vol. 16, No. 3 ( 2017-09), p. 154-162
    Abstract: Traditional Chinese medicine has great potential to improve wound healing. ANBP, the mixture of 4 Chinese herbs— Agrimoniapilosa, Nelumbonucifera, Boswelliacarteri, and Pollen typhae—is effective in trauma treatment while its mechanism is still elusive. In this study, quantitative proteomics and bioinformatics analyses were performed to decipher the possible roles of ANBP in accelerated wound healing of mouse skin. Among all 3171 identified proteins, 90, 71, 80, and 140 proteins were found to be differently expressed in 6 hours, 3 days, 7 days, and 14 days ANBP-treated tissues compared with corresponding control tissues, respectively. The result showed that different biological processes and pathways were activated at different healing stages. At the early healing stage, ANBP treatment mainly affected several biological processes, including immune and defense response, vascular system restoration, hemostasis and coagulation regulation, lipid metabolism and signal transduction, while muscle tissue, hair, epidermis, extracellular matrix and tissue remodeling related activities were the major events in ANBP promoted later wound healing. This is the first quantitative proteome study of ANBP-treated wound tissues, which provide a new perspective for the mechanism of ANBP accelerated wound healing and is of guiding significance for clinical application of ANBP in trauma disorders cure.
    Type of Medium: Online Resource
    ISSN: 1534-7346 , 1552-6941
    URL: Article
    DOI: 10.1177/1534734617720623
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2017
    detail.hit.zdb_id: 2135166-1
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  • 5
    Online Resource
    Online Resource
    Path following control for a stratospheric airship with actuator saturation
    SAGE Publications ; 2017
    In:  Transactions of the Institute of Measurement and Control Vol. 39, No. 7 ( 2017-07), p. 987-999
    Details
    In: Transactions of the Institute of Measurement and Control, SAGE Publications, Vol. 39, No. 7 ( 2017-07), p. 987-999
    Abstract: This paper proposes two different path following control schemes for a stratospheric airship with actuator saturation. Each of the control schemes consists of a guidance loop and an attitude control loop. In both schemes, guidance laws are designed according to the line-of-sight guidance-based path following principle. In the first control scheme, a robust H∞ controller without constraints is designed based on the planar model of a stratospheric airship to stabilize path-following errors. The input constraints are then addressed by using a regional [Formula: see text]-based model recovery anti-windup compensator, which prevents the unconstrained controller from misbehaving in the constrained closed loop with anti-windup augmentation and ensures the systematic stability. In the second control scheme, model predictive control is applied to guarantee the path-following of the closed-loop system and explicitly address the magnitude an d rate of rudders of the stratospheric airship. Theoretical results are illustrated by numerical simulations where both closed-loop systems are capable of following their desired paths and the constraints on control inputs are satisfied.
    Type of Medium: Online Resource
    ISSN: 0142-3312 , 1477-0369
    URL: Article
    DOI: 10.1177/0142331215625770
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2017
    detail.hit.zdb_id: 2025882-3
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  • 6
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    Online Resource
    Base-promoted synthesis of N -arylbenzamides by N -benzoylation of dimethylphenylthioureas
    SAGE Publications ; 2017
    In:  Journal of Chemical Research Vol. 41, No. 8 ( 2017-08), p. 484-486
    Details
    In: Journal of Chemical Research, SAGE Publications, Vol. 41, No. 8 ( 2017-08), p. 484-486
    Abstract: An efficient synthesis of 10 N-arylbenzamides was achieved by N-benzoylation of N,N-dimethyl-( N′-phenyl)thioureas with 4-substituted benzoyl chlorides in dimethylacetamide in the presence of K 2 CO 3 . The features of this method include good yields, short reaction times and broad substrate scope. This work showed that arylthiourea derivatives can be alternative and useful starting materials for the preparation of N-arylbenzamides.
    Type of Medium: Online Resource
    ISSN: 1747-5198 , 2047-6507
    URL: Article
    DOI: 10.3184/174751917X15016635672213
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2017
    detail.hit.zdb_id: 3010810-X
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  • 7
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    Online Resource
    Comparative utility of MRI perfusion with MSIDR and DWIBS for the characterization of breast tumors
    SAGE Publications ; 2012
    In:  Acta Radiologica Vol. 53, No. 6 ( 2012-07), p. 607-614
    Details
    In: Acta Radiologica, SAGE Publications, Vol. 53, No. 6 ( 2012-07), p. 607-614
    Abstract: In recent years, breast magnetic resonance imaging (MRI) has been used to evaluate the morphology and functional markers of breast lesions, which might influence local staging and surgical planning. Purpose To evaluate the feasibility of a one stop MRI protocol combined with diffusion-weighted imaging with background body signal suppression (DWIBS), T2*-weighted perfusion imaging (T2*-PWI) and delayed contrast-enhanced T1-weighted MRI (T1W-C+). Material and Methods All experiments were conducted with a 3-T clinical MRI scanner. The apparent diffusion coefficient (ADC) and detectability of lesions in DWIBS, the maximal signal intensity drop rate (MSIDR) in T2*-PWI and the intensity increasing rate (IIR) on T1W-C+ were compared between breast malignancies ( n = 29) and benign lesions ( n = 31). The time–signal curves in the T2*-PWI sequences were classified into two subtypes (a and b) according to the end of the curve. The ADC, MSIDR, the first maximal signal intensity decrease time (MSIDT), and IIR between the malignant and benign lesions were statistically analyzed by unpaired t-tests. Results Overall, 90% of the lesions were detected by DWIBS. There were significant differences in ADC, MSIDR, and IIR between the carcinomas and benign lesions. The Ib subtype in T2*-PWI demonstrated a specificity of 66.7% in differentiating between carcinomas and benign lesions. At a fixed specificity of 93.5%, the MSIDR, IIR, and ADC differentiated breast carcinomas from benign lesions with sensitivities of 82.8%, 44.8%, and 86.2%, respectively. Conclusion DWIBS might be a compensation sequence for detecting breast lesions in pre-contrast sequences. MSIDR from T2*-PWI had the best specificity index, and the two subtypes in the T2*-PWI curve were helpful in the differential diagnosis of carcinomas from benign lesions.
    Type of Medium: Online Resource
    ISSN: 0284-1851 , 1600-0455
    URL: Article
    DOI: 10.1258/ar.2012.120064
    RVK:
    XA 10000
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2012
    detail.hit.zdb_id: 2024579-8
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  • 8
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    Investigation of the recycling of continuous fiber-reinforced thermoplastics
    SAGE Publications ; 2019
    In:  Journal of Thermoplastic Composite Materials Vol. 32, No. 3 ( 2019-03), p. 342-356
    Details
    In: Journal of Thermoplastic Composite Materials, SAGE Publications, Vol. 32, No. 3 ( 2019-03), p. 342-356
    Abstract: There is limited information on the recycling of continuous fiber-reinforced thermoplastics (FRTPs). Furthermore, existing research has been conducted in laboratories on a very small scale. In this article, we propose an effective and simple technology for recycling of FRTPs, which can be conducted on a large scale. To accelerate the rate of resin dissolution, prepared FRTPs were cut into small pieces. The obtained pieces were used to manufacture recycled chopped fabric tape-reinforced thermoplastics (R-CTTs). The feasibility of the recycling technology was confirmed by comparing the mechanical properties of the composites made from virgin materials (virgin chopped fabric tape-reinforced thermoplastics (V-CTTs)) and recycled materials. There was a significant improvement of the tensile properties with the increase of the specimen thickness. The strength of the materials was more sensitive to the length of the chopped tape than the modulus. Fibers in both V-CTT and R-CTT were well connected with the resins, as confirmed by scanning electron microscopy.
    Type of Medium: Online Resource
    ISSN: 0892-7057 , 1530-7980
    URL: Article
    DOI: 10.1177/0892705718759388
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2019
    detail.hit.zdb_id: 2098671-3
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  • 9
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    Online Resource
    CD25 Is a Novel Marker of Hepatic Bile Canaliculus
    SAGE Publications ; 2012
    In:  International Journal of Surgical Pathology Vol. 20, No. 5 ( 2012-10), p. 455-461
    Details
    In: International Journal of Surgical Pathology, SAGE Publications, Vol. 20, No. 5 ( 2012-10), p. 455-461
    Abstract: Objective. Although many antigens have been investigated, the method for the bile canaliculus staining using optical microscopy needs to be improved. The aim of the present study was to assess the expression pattern of a candidate marker, CD25, in normal and diseased liver tissue. Methods. Immunohistochemistry, immunofluorescence, and immune electron microscopy assays were performed with 41 liver sections and 2 different anti-CD25 monoclonal antibodies. A polyclonal antibody against carcinoembryonic antigen (CEA) was also used to stain bile canaliculus as a control. CD25 expression levels in normal and diseased liver tissue were also determined. Results. CD25 was predominantly localized at the bile canaliculus of adult and infantile liver, evidenced by both immunohistochemistry and immunofluorescence assays. The electron microscopy assay showed that there were obvious amorphous electron-dense deposits at the bile canaliculus. In contrast, the CEA-positive area included bile canaliculus as well as basolateral aspects of hepatocytes. CD25 expression levels did not differ significantly among different disease states. Conclusion. This study provides the first evidence that CD25 is a novel marker of bile canaliculus. Characteristics of CD25 expression may shed light on immunohistochemistry and immunofluorescence analysis of bile canaliculus in both basic and clinical hepatic investigations.
    Type of Medium: Online Resource
    ISSN: 1066-8969 , 1940-2465
    URL: Article
    DOI: 10.1177/1066896912444158
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2012
    detail.hit.zdb_id: 2070102-0
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  • 10
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    Research on interaction law of longitudinal/lateral slip of mountain tractor based on tire-soil model
    SAGE Publications ; 2023
    In:  Proceedings of the Institution of Mechanical Engineers, Part D: Journal of Automobile Engineering
    Details
    In: Proceedings of the Institution of Mechanical Engineers, Part D: Journal of Automobile Engineering, SAGE Publications
    Abstract: When the mountain tractor is along the slope contour operation, the driving wheel will cause a longitudinal or lateral slip due to complex driving conditions. In order to investigate the influence law between the longitudinal slip, lateral slip, and deflection slip, the parametrically modified wheel-soil model, dynamics model, and motion trajectory model were established, and the tractor lateral slope simulation model was built based on MATLAB/Simulink and CarSim software. The simulation results show that load traction has the most significant effect on the longitudinal slip rate, lateral slope variation has the most significant impact on the side-slip angle and lateral slip rate, and the lateral slope and load traction together affect the yaw angle and deflection slip rate. When the lateral slope is 15°, the tractor longitudinal speed of 3 and 6 km/h can maintain lateral stability of the longitudinal slip rate of 0.39 and 0.25, respectively. In order to verify the accuracy of the simulation model, the test platform was built. The results show that the average errors of the absolute values of left longitudinal slip rate, right longitudinal slip rate, yaw angle, and side-slip angle are 14.47%, 13.06%, 12.27%, and 11.04%, respectively. To sum up, the extreme driving conditions of the tractor will aggravate the longitudinal slip of the driving wheel, which in turn affects the lateral slip and deflection slip, and should be controlled to avoid tractor instability.
    Type of Medium: Online Resource
    ISSN: 0954-4070 , 2041-2991
    URL: Article
    DOI: 10.1177/09544070231184506
    RVK:
    ZO 4200
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2023
    detail.hit.zdb_id: 2032754-7
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