GLORIA

GEOMAR Library Ocean Research Information Access

X

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • SAGE Publications  (15)
  • 1
    Online Resource
    Online Resource
    Investigation of transient flow characteristics inside a centrifugal compressor for design and off-design conditions
    SAGE Publications ; 2018
    In:  Proceedings of the Institution of Mechanical Engineers, Part A: Journal of Power and Energy Vol. 232, No. 4 ( 2018-06), p. 364-385
    Details
    In: Proceedings of the Institution of Mechanical Engineers, Part A: Journal of Power and Energy, SAGE Publications, Vol. 232, No. 4 ( 2018-06), p. 364-385
    Abstract: As the flow rate decreases from the design to the rotating stall condition, the enhanced impeller–diffuser interaction considerably deteriorates the flow condition at the diffuser inlet, which may trigger stall and blade vibration problems. In order to reveal the underlying mechanism and estimate the impact of the interaction within the impeller and diffuser passages, measurements using the wireless acquisition technique and high-frequency response system have been conducted on a 1.5 stage centrifugal compressor with the vaned diffuser. The details of its transient flow characteristics suggest that the effects of the impeller sweep extensively propagate in the diffuser passage. Distinctions of the shroud reversed vortex effect exist between the main and splitter blades at the impeller outlet, which initiates the predominant passage passing frequency at the diffuser inlet under small flow rate condition. In addition, the present study explains why the dominant disturbance shifts back and force between the passage passing frequency and blade passing frequency for different positions of the diffuser and flow rates. Through flow throttling, the diffuser reaction toward the impeller passage considerably strengthens due to the growing pressure potential near the convex surface of the diffuser vane, which is associated with the reversed flow.
    Type of Medium: Online Resource
    ISSN: 0957-6509 , 2041-2967
    URL: Article
    DOI: 10.1177/0957650917738848
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2018
    detail.hit.zdb_id: 2024892-1
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 2
    Online Resource
    Online Resource
    Traffic Risk Assessment of Lane-Changing Process in Urban Inter-Tunnel Weaving Segment
    SAGE Publications ; 2023
    In:  Transportation Research Record: Journal of the Transportation Research Board Vol. 2677, No. 10 ( 2023-10), p. 95-106
    Details
    In: Transportation Research Record: Journal of the Transportation Research Board, SAGE Publications, Vol. 2677, No. 10 ( 2023-10), p. 95-106
    Abstract: This study aims to assess the traffic risk of the lane-changing (LC) process in the urban inter-tunnel weaving (UIW) segment. Time to collision (TTC) and extended time to collision (ETTC) are selected as indices for traffic risk assessment. An instantaneous traffic risk level classification method integrating Pareto’s law and the K-means clustering algorithm is proposed. Based on the classification results, the study also proposes an overall LC risk assessment method. Field-collected trajectory data are used to evaluate and characterize the traffic risk associated with the LC process. The instantaneous traffic risk analysis shows that the high-risk state accounts for a high percentage of the LC process in the UIW segment, and the front vehicle on the starting lane has the highest potential for conflict with the target vehicle. The overall risk index analysis shows that the risk distribution of the LC process is significantly clustered in the weaving segment and that the safety level of the UIW segment needs to be improved. This study quantifies the safety level and analyzes the characteristics of traffic risks of the LC process in the UIW segment to provide a decision basis for the development of assisted driving schemes and improvement of traffic safety management in the UIW segment.
    Type of Medium: Online Resource
    ISSN: 0361-1981 , 2169-4052
    URL: Article
    DOI: 10.1177/03611981231160171
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2023
    detail.hit.zdb_id: 2403378-9
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 3
    Online Resource
    Online Resource
    3D printed biocompatible graphene oxide, attapulgite, and collagen composite scaffolds for bone regeneration
    SAGE Publications ; 2022
    In:  Journal of Biomaterials Applications Vol. 36, No. 10 ( 2022-05), p. 1838-1851
    Details
    In: Journal of Biomaterials Applications, SAGE Publications, Vol. 36, No. 10 ( 2022-05), p. 1838-1851
    Abstract: Tissue-engineered bone material is one of the effective methods to repair bone defects, but the application is restricted in clinical because of the lack of excellent scaffolds that can induce bone regeneration as well as the difficulty in making scaffolds with personalized structures. 3D printing is an emerging technology that can fabricate bespoke 3D scaffolds with precise structure. However, it is challenging to develop the scaffold materials with excellent printability, osteogenesis ability, and mechanical strength. In this study, graphene oxide (GO), attapulgite (ATP), type I collagen (Col I) and polyvinyl alcohol were used as raw materials to prepare composite scaffolds via 3D bioprinting. The composite materials showed excellent printability. The microcosmic architecture and properties was characterized by scanning electron microscopy, Fourier transform infrared and thermal gravimetric analyzer, respectively. To verify the biocompatibility of the scaffolds, the viability, proliferation and osteogenic differentiation of Bone Marrow Stromal Cells (BMSCs) on the scaffolds were assessed by CCK-8, Live/Dead staining and Real-time PCR in vitro. The composited scaffolds were then implanted into the skull defects on rat for bone regeneration. Hematoxylin-eosin staining, Masson staining and immunohistochemistry staining were carried out in vivo to evaluate the regeneration of bone tissue. The results showed that GO/ATP/COL scaffolds have been demonstrated to possess controlled porosity, water absorption, biodegradability and good apatite-mineralization ability. The scaffold consisting of 0.5% GO/ATP/COL have excellent biocompatibility and was able to promote the growth, proliferation and osteogenic differentiation of mouse BMSCs in vitro. Furthermore, the 0.5% GO/ATP/COL scaffolds were also able to promote bone regeneration of in rat skull defects. Our results illustrated that the 3D printed GO/ATP/COL composite scaffolds have good mechanical properties, excellent cytocompatibility for enhanced mouse BMSCs adhesion, proliferation, and osteogenic differentiation. All these advantages made it potential as a promising biomaterial for osteogenic reconstruction.
    Type of Medium: Online Resource
    ISSN: 0885-3282 , 1530-8022
    URL: Article
    DOI: 10.1177/08853282211067646
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2022
    detail.hit.zdb_id: 2072559-0
    SSG: 12
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 4
    Online Resource
    Online Resource
    Intraoperative hypotension during surgical treatment for Marfan syndrome scoliosis in children
    SAGE Publications ; 2022
    In:  Journal of Children's Orthopaedics Vol. 16, No. 5 ( 2022-10), p. 416-423
    Details
    In: Journal of Children's Orthopaedics, SAGE Publications, Vol. 16, No. 5 ( 2022-10), p. 416-423
    Abstract: To explore the occurrence and risk factors of intraoperative hypotension during children’s Marfan syndrome scoliosis surgery and summarize the associated hemodynamic features and handle measures. Methods: Twenty-two Marfan syndrome scoliosis patients who underwent spinal surgery at Beijing Children’s Hospital were retrospectively reviewed between January 2001 and January 2020. Intraoperative hypotension is defined as the minimum mean arterial pressure ≤ 60 mm Hg. The patients were divided into the hypotension group and the control group. Clinical, radiographic, and operative data were compared between the two groups. The risk factors, hemodynamic features, and handle measures for intraoperative hypotension in Marfan syndrome scoliosis surgery were analyzed and summarized. Results: Twenty-two patients were included in the study, with a mean age of 11.4 years at initial surgery. The follow-up period ranged from 24 to 152 months. Intraoperative hypotension occurred in 14 cases, with an incidence of 63.6%. The proportion of pulmonary dysfunction in the hypotension group was higher than in the control group (100.0% vs 50.0%, p  〈  0.05). The spinal flexibility was significantly lower in the hypotension group (28.3% ± 14.2% vs 46.5% ± 11.5%, p  〈  0.05). Fourteen patients with intraoperative hypotension had decreased intraoperative systolic blood pressure 21.0%–50.0% compared with baseline. One patient had a transient decrease in the muscle strength of the lower limbs. No complications were observed during the follow-up. Conclusion: The incidence of intraoperative hypotension in Marfan syndrome scoliosis children who underwent surgery was 63.6%. The risk factors included preoperative pulmonary dysfunction and poor spinal flexibility. Comprehensive preoperative evaluation and effective hemodynamic handling measures should be undertaken to prevent further complications in children with Marfan syndrome scoliosis.
    Type of Medium: Online Resource
    ISSN: 1863-2521 , 1863-2548
    URL: Article
    DOI: 10.1177/18632521221126923
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2022
    detail.hit.zdb_id: 2268264-8
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 5
    Online Resource
    Online Resource
    Impact of the ending position of controllable speed casing on the flow stability in a transonic compressor rotor
    SAGE Publications ; 2023
    In:  Proceedings of the Institution of Mechanical Engineers, Part A: Journal of Power and Energy Vol. 237, No. 5 ( 2023-08), p. 845-856
    Details
    In: Proceedings of the Institution of Mechanical Engineers, Part A: Journal of Power and Energy, SAGE Publications, Vol. 237, No. 5 ( 2023-08), p. 845-856
    Abstract: The structure of casing treatment has a significant influence on the stability expansion effect. The ending position of the rotatable ring is one of the important structural parameters in the controllable speed casing. The impact of ending position of the rotatable ring rotating at the same speed as the rotor on the stability expansion and stability expansion mechanism was studied in this paper. The results show that, when the ending position of rotatable ring expands downstream in the range of 20% to 60% axial chord length, because of the improvement in the tip leakage vortex trajectory and main flow/leakage flow interface, the stability expansion effect rises gradually. The further downstream expansion of ending position from 60% axial chord length, however, has a slight impact on tip flow, bringing out a steady stability expansion effect around 52.5%. The best stability expansion effect of ending position occurs at 60% axial chord length where the stable operating margin increases by 53.5%.
    Type of Medium: Online Resource
    ISSN: 0957-6509 , 2041-2967
    URL: Article
    DOI: 10.1177/09576509231151484
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2023
    detail.hit.zdb_id: 2024892-1
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 6
    Online Resource
    Online Resource
    ZO-1 expression is suppressed by GM-CSF via miR-96/ERG in brain microvascular endothelial cells
    SAGE Publications ; 2018
    In:  Journal of Cerebral Blood Flow & Metabolism Vol. 38, No. 5 ( 2018-05), p. 809-822
    Details
    In: Journal of Cerebral Blood Flow & Metabolism, SAGE Publications, Vol. 38, No. 5 ( 2018-05), p. 809-822
    Abstract: The level of granulocyte-macrophage colony-stimulating factor (GM-CSF) increases in some disorders such as vascular dementia, Alzheimer’s disease, and multiple sclerosis. We previously reported that in Alzheimer’s disease patients, a high level of GM-CSF in the brain parenchyma downregulated expression of ZO-1, a blood–brain barrier tight junction protein, and facilitated the infiltration of peripheral monocytes across the blood–brain barrier. However, the molecular mechanism underlying regulation of ZO-1 expression by GM-CSF is unclear. Herein, we found that the erythroblast transformation-specific (ETS) transcription factor ERG cooperated with the proto-oncogene protein c-MYC in regulation of ZO-1 transcription in brain microvascular endothelial cells (BMECs). The ERG expression was suppressed by miR-96 which was increased by GM-CSF through the phosphoinositide-3 kinase (PI3K)/Akt pathway. Inhibition of miR-96 prevented ZO-1 down-regulation induced by GM-CSF both in vitro and in vivo. Our results revealed the mechanism of ZO-1 expression reduced by GM-CSF, and provided a potential target, miR-96, which could block ZO-1 down-regulation caused by GM-CSF in BMECs.
    Type of Medium: Online Resource
    ISSN: 0271-678X , 1559-7016
    URL: Article
    DOI: 10.1177/0271678X17702668
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2018
    detail.hit.zdb_id: 2039456-1
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 7
    Online Resource
    Online Resource
    Effectiveness of Music Therapy on Improving Treatment Motivation and Emotion in Female Patients with Methamphetamine Use Disorder: A Randomized Controlled Trial
    SAGE Publications ; 2020
    In:  Substance Abuse Vol. 41, No. 4 ( 2020-10), p. 493-500
    Details
    In: Substance Abuse, SAGE Publications, Vol. 41, No. 4 ( 2020-10), p. 493-500
    Abstract: The purpose of the study was to investigate whether Group Music Therapy (GMT) could enhance the treatment motivation and change the negative emotion among female patients with methamphetamine use disorder in a randomized clinical trial. Methods Participants ( N = 60) were randomized to the group of GMT combined with treatment as usual (TAU) or the group with TAU only. Questionnaire of Motivation for Abstaining from Drugs was used to measure the motivation for abstaining from drugs of the female patients. And Self-Rating Depression Scale and Self-Rating Anxiety Scale were used to measure negative emotion of participants. The measurements were conducted at T0 (baseline), T1 (post 13 sessions of intervention) and T2 (3-month follow-up after T1) by the independent trained researcher. Results The postintervention and 3-month follow-up results according to the intention-to-treat principle indicated that GMT + TAU intervention showed significantly positive group-by-time effect on the scores of the subscale-tending to rehabilitation-internal motivation ( p = 0.01) and avoiding abuse-external motivation ( p = 0.04). In 3-month follow-up, total scores of the questionnaire of motivation for abstaining from drugs ( p = 0.02), scores of avoiding abuse-internal motivation subscale ( p = 0.05), and scores of confidence of abstaining from drugs subscale ( p = 0.01) in GMT + TAU were also presented with significantly positive group x time effect. The changes of total score of Questionnaire of Motivation for Abstaining from Drugs (from baseline to 3-month follow-up) was significantly positive association with the changes of scores of SAS in GMT + TAU group ( r = −0.55, p = 0.00). Conclusions The present study suggests that GMT could be used as an effective treatment strategy to enhance treatment motivation of female patients with methamphetamine use disorder.
    Type of Medium: Online Resource
    ISSN: 0889-7077 , 1547-0164
    URL: Article
    DOI: 10.1080/08897077.2019.1675117
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2020
    detail.hit.zdb_id: 2018838-9
    SSG: 5,2
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 8
    Online Resource
    Online Resource
    Side Effects of Large-Scale Assessments in Education
    SAGE Publications ; 2019
    In:  ECNU Review of Education Vol. 2, No. 3 ( 2019-09), p. 279-296
    Details
    In: ECNU Review of Education, SAGE Publications, Vol. 2, No. 3 ( 2019-09), p. 279-296
    Abstract: In line with a recent call for side effects research in education, this article aims to synthesize the major concerns that have been raised in the literature concerning large-scale assessments (LSAs) in education. Design/Approach/Methods: The researchers endeavored to complete a deep review of the literature on LSAs to synthesize the reported side effects. The review was synthesized thematically to understand and report the consequences of the ongoing push for the use of LSA in education. Findings: Thematic analysis indicated overarching side effects of LSA in education. We discuss why negative side effects exist and present evidence of the most commonly observed side effects of LSA in education, including distorting education, exacerbating inequity and injustice, demoralization of professionals, ethical corruption, and stifling of innovation in education. Originality/Value: While concerns about the use and misuse of LSA in education are not new and have been discussed widely in the literature, rarely have they been discussed as inherent qualities and consequences of LSAs that can do harm to education.
    Type of Medium: Online Resource
    ISSN: 2096-5311 , 2632-1742
    URL: Article
    DOI: 10.1177/2096531119878964
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2019
    detail.hit.zdb_id: 3010076-8
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 9
    Online Resource
    Online Resource
    Geochemical response of deep geothermal processes in the Litang region, Western Sichuan
    SAGE Publications ; 2019
    In:  Energy Exploration & Exploitation Vol. 37, No. 2 ( 2019-03), p. 626-645
    Details
    In: Energy Exploration & Exploitation, SAGE Publications, Vol. 37, No. 2 ( 2019-03), p. 626-645
    Abstract: The geochemical characteristics of geothermically heated water can reveal deep geothermal processes, leading to a better understanding of geothermal system genesis and providing guidance for improved development and utilization of such resources. Hydrochemical and hydrogen oxygen isotope analysis of two geothermal field (district) hot springs based on regional geothermal conditions revealed that the thermal water in the Litang region is primarily of the HCO 3 Na type. The positive correlations found between F − , Li 2+ , As + , and Cl − indicated a common origin, and the relatively high Na + and metaboric acid concentrations suggested a relatively long groundwater recharge time and a slow flow rate. The values of δD and δ 18 O were well distributed along the local meteoric line, indicating a groundwater recharge essentially driven by precipitation. The thermal reservoir temperature (152°C–195°C) and thermal cycle depth (3156–4070 m) were calculated, and the cold water mixing ratio (60%–68%) was obtained using the silica-enthalpy model. Finally, hydrogeochemical pathway simulation was used to analyze the evolution of geothermal water in the region. The results were further supported by the high metasilicate content in the region. Of the geothermal fields in the region, it was found that the Kahui is primarily affected by albite, calcite precipitation, and silicate, while the Gezha field is primarily affected by calcite dissolution, dolomite precipitation, and silicate.
    Type of Medium: Online Resource
    ISSN: 0144-5987 , 2048-4054
    URL: Article
    DOI: 10.1177/0144598718812550
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2019
    detail.hit.zdb_id: 2026571-2
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 10
    Online Resource
    Online Resource
    Lipoxin A4 promotes autophagy and inhibits overactivation of macrophage inflammasome activity induced by Pg LPS
    SAGE Publications ; 2021
    In:  Journal of International Medical Research Vol. 49, No. 2 ( 2021-02), p. 030006052098125-
    Details
    In: Journal of International Medical Research, SAGE Publications, Vol. 49, No. 2 ( 2021-02), p. 030006052098125-
    Abstract: To explore the role of lipoxin A4 (LXA4) on inflammasome and inflammatory activity in macrophages activated by Porphyromonas gingivalis lipopolysaccharide (PgLPS) one of the major causative agents of chronic periodontitis. Methods The mouse macrophage cell line RAW264.7 was used to produce an activated inflammation model. Markers of inflammasome and inflammatory activity and autophagy were assessed by ELISA, reverse transcription polymerase chain reaction (RT-PCR), and Western blot assay. Results Markers of inflammasome activity, inflammation and autophagy increased with Pg LPS concentration. They also increased with increasing exposure to Pg LPS up to 12h but decreased at 24h. However, markers of autophagy increased. Phosphorylated NF-κBp65 decreased with LXA4, which was similar to results obtained with the autophagy inducer, rapamycin. Conclusions LXA4 promoted autophagy and inhibited activation of inflammasomes and inflammation markers in macrophage inflammation induced by PgLPS and this action was linked to the phosphorylation of NF-κB.
    Type of Medium: Online Resource
    ISSN: 0300-0605 , 1473-2300
    URL: Article
    DOI: 10.1177/0300060520981259
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2021
    detail.hit.zdb_id: 2082422-1
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...