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  • SAGE Publications  (125)
  • 1
    Online Resource
    Online Resource
    Improvement in dyeing and physical properties of wool fabrics through pretreatment based on the bacterial culture of Stenotrophomonas maltophilia DHHJ
    SAGE Publications ; 2022
    In:  Textile Research Journal Vol. 92, No. 23-24 ( 2022-12), p. 4596-4605
    Details
    In: Textile Research Journal, SAGE Publications, Vol. 92, No. 23-24 ( 2022-12), p. 4596-4605
    Abstract: Wool fiber is a valuable natural material in the textile industry, but keratin cuticles on its surface can deteriorate product quality. Wool fabric finishing has a long-standing problem in meeting the goal of environmental sustainability. In this study, we developed an eco-friendly simple method of wool fabric treatment based on direct incubation with the whole culture of Stenotrophomonas maltophilia DHHJ, a keratinase-producing bacterial strain. This processing method effectively reduced roughness for the surface of wool fiber and wool fabric samples by removing the cuticle scales. The keratinolytic treatment altered many physical properties of the wool fabrics, such as felting shrink, bursting strength, elongation at break, and diameter. The dyeability of wool fabric was substantially improved due to the pretreatment. The surface modification accelerated the rate of dyeing-bath exhaustion for wool fabric samples under a mild processing condition and the dyeing equilibrium was achieved within 10 min at a relatively low dyebath temperature (below 70°C). The pretreatment with the keratinase-secreting bacterial culture was beneficial for dyeing uniformity and rubbing color fastness. Besides, the fuzzing and pilling properties of wool fabrics were ameliorated in the fabric samples incubated with the bacterial culture.
    Type of Medium: Online Resource
    ISSN: 0040-5175 , 1746-7748
    URL: Article
    DOI: 10.1177/00405175221106231
    RVK:
    ZS 0001
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2022
    detail.hit.zdb_id: 2209596-2
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  • 2
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    Effectiveness of acupuncture for vascular cognitive impairment no dementia: a randomized controlled trial
    SAGE Publications ; 2019
    In:  Clinical Rehabilitation Vol. 33, No. 4 ( 2019-04), p. 642-652
    Details
    In: Clinical Rehabilitation, SAGE Publications, Vol. 33, No. 4 ( 2019-04), p. 642-652
    Abstract: To evaluate the effectiveness of acupuncture in patients with vascular cognitive impairment no dementia (VCIND) in comparison with citicoline, an agent for cognitive disturbances associated with chronic cerebral disorders. Design: A randomized controlled multicenter trial. Setting: In three hospitals in Beijing, China. Subjects: A total of 216 patients with VCIND were recruited. Interventions: Patients with VCIND (mean age of 65.4 years) were randomized to receive acupuncture (two sessions per week) or oral citicoline (100 mg three times daily) over three months. Main measures: The primary outcome was the change from baseline to three months in cognitive symptom, measured by Alzheimer’s disease Assessment Scale, cognitive subscale (ADAS-cog). Secondary outcomes included changes from baseline to six months in ADAS-cog, executive function measured by the Clock Drawing Test (CDT), and functional disability measured by the Ability of Daily Living (ADL) scale at three and six months. Results: At three months, the acupuncture group had a greater decrease in mean ADAS-cog score (−2.33 ± 0.31) than the citicoline group (−1.38 ± 0.34) with a mean difference of −0.95 (95% CI, −1.84 to −0.07, P = 0.035). The mean change from baseline to six months in ADAS-cog also significantly favored acupuncture treatments (acupuncture change −2.61 vs citicoline −1.25, difference: −1.36 points; 95% CI, −2.20 to −0.51; P = 0.002). There was no difference between the two groups on CDT and ADL scores at either time point. Conclusion: Compared with citicoline, acupuncture has comparable and even superior efficacy with improved cognitive and daily living performance as a complementary and alternative medicine treatment for VCIND.
    Type of Medium: Online Resource
    ISSN: 0269-2155 , 1477-0873
    URL: Article
    DOI: 10.1177/0269215518819050
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2019
    detail.hit.zdb_id: 2028323-4
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  • 3
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    Clinical Cell Therapy Guidelines for Neurorestoration (IANR/CANR 2017)
    SAGE Publications ; 2018
    In:  Cell Transplantation Vol. 27, No. 2 ( 2018-02), p. 310-324
    Details
    In: Cell Transplantation, SAGE Publications, Vol. 27, No. 2 ( 2018-02), p. 310-324
    Abstract: Cell therapy has been shown to be a key clinical therapeutic option for central nervous system diseases or damage. Standardization of clinical cell therapy procedures is an important task for professional associations devoted to cell therapy. The Chinese Branch of the International Association of Neurorestoratology (IANR) completed the first set of guidelines governing the clinical application of neurorestoration in 2011. The IANR and the Chinese Association of Neurorestoratology (CANR) collaborated to propose the current version “Clinical Cell Therapy Guidelines for Neurorestoration (IANR/CANR 2017)”. The IANR council board members and CANR committee members approved this proposal on September 1, 2016, and recommend it to clinical practitioners of cellular therapy. These guidelines include items of cell type nomenclature, cell quality control, minimal suggested cell doses, patient-informed consent, indications for undergoing cell therapy, contraindications for undergoing cell therapy, documentation of procedure and therapy, safety evaluation, efficacy evaluation, policy of repeated treatments, do not charge patients for unproven therapies, basic principles of cell therapy, and publishing responsibility.
    Type of Medium: Online Resource
    ISSN: 0963-6897 , 1555-3892
    URL: Article
    DOI: 10.1177/0963689717746999
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2018
    detail.hit.zdb_id: 2020466-8
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  • 4
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    Factors Associated With Hospitalization Costs of Coronary Heart Disease in Township Hospitals in Rural China
    SAGE Publications ; 2019
    In:  INQUIRY: The Journal of Health Care Organization, Provision, and Financing Vol. 56 ( 2019-01), p. 004695801988695-
    Details
    In: INQUIRY: The Journal of Health Care Organization, Provision, and Financing, SAGE Publications, Vol. 56 ( 2019-01), p. 004695801988695-
    Abstract: In large proportions of rural areas in many developing countries, health care delivery system is less developed and is less likely to be equipped to conduct sophisticated treatment for coronary heart disease (CHD) patients locally. This study aims at describing the status quo of and exploring factors associated with hospitalization costs of CHD in township hospitals where only drug therapy was available for CHD conditions. We collected data of inpatients with CHD from discharge records from 10 township hospitals in rural Liaoning from December 2013 to December 2014. We used multilevel linear regression to analyze the factors associated with CHD hospitalization costs. A total of 4635 inpatients were included in the analysis. We found that the average hospitalization costs were 6249.97 RMB (US$1012.47) with the average of 8.89 days of hospitalization in township hospitals in Liaoning. Age, gender, length of stay, the number of times of admissions, by which route was hospitalized, and type of CHD were all the factors significantly associated with hospitalization costs of CHD in township hospitals. The factors associated with hospitalization costs of CHD in township hospitals in rural China showed some different features from the existing studies. When the government designs the related policy, the policy makers need to consider the specific feature of hospitalization costs of CHD in township hospitals in rural areas.
    Type of Medium: Online Resource
    ISSN: 0046-9580 , 1945-7243
    URL: Article
    DOI: 10.1177/0046958019886958
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2019
    detail.hit.zdb_id: 2147137-X
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  • 5
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    A dynamic event-triggered network control algorithm combined with gradient-sharing asynchronous advantage actor-critic strategy
    SAGE Publications ; 2023
    In:  Transactions of the Institute of Measurement and Control
    Details
    In: Transactions of the Institute of Measurement and Control, SAGE Publications
    Abstract: In the existing memory event-triggered control (METC) algorithms, the threshold parameters and memory weights are fixed, reducing the system’s adaptability. In this paper, a new intelligent dynamic METC algorithm is proposed to reduce the amount of transmission data and decrease the communication burden in networked control systems. The proposed dynamic METC mechanism applies the gradient-sharing asynchronous advantage actor-critic (A3C-GS) learning algorithm to optimized memory event-triggered function of memory weights and threshold parameters. A time-varying delay system model for dynamic METC is developed by incorporating the A3C-GS for the networked control system with communication delays. Then, by solving two linear matrix inequalities (LMIs), the controller gain parameters of the networked control systems are derived. Finally, the performance of the proposed new METC algorithm is compared with the current three event-triggered control methods. Simulation results show that the proposed intelligent event-triggered algorithm reduces the number of triggers by about 40% compared with the traditional event-triggered algorithm under the pregiven simulation time. Thus, the effectiveness of the main results is verified.
    Type of Medium: Online Resource
    ISSN: 0142-3312 , 1477-0369
    URL: Article
    DOI: 10.1177/01423312231159698
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2023
    detail.hit.zdb_id: 2025882-3
    SSG: 3,2
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  • 6
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    Molecularly imprinted polymeric microspheres with metalloporphyrin-based molecular recognition sites coassembled with methacrylic acid
    SAGE Publications ; 2013
    In:  High Performance Polymers Vol. 25, No. 7 ( 2013-11), p. 790-797
    Details
    In: High Performance Polymers, SAGE Publications, Vol. 25, No. 7 ( 2013-11), p. 790-797
    Abstract: Molecularly imprinted polymeric microspheres (MIPMs) for dimethyl methylphosphonate (DMMP) were prepared using methacrylic acid (MAA) and vinyl-substituted zinc(ii) porphyrin as functional monomers. The interactions of vinyl-substituted zinc(ii) porphyrin with DMMP were determined by ultraviolet–visible absorption spectroscopy. A comparison between the MIPMs-MAA that used only MAA with the MIPMs-zinc (Zn) + MAA that used both MAA and Zn porphyrin as functional monomers revealed that the MIPMs-Zn + MAA showed higher binding ability for DMMP. By the Scatchard analysis, the results of the equilibrium adsorption test showed that the MIPM-DMMP only had one affinity binding site. The dissociation constants of MIPMs-Zn + MAA and MIPMs-MAA were 0.167 and 0.338 mmol/L, respectively, and the maximum absorption quantities were 148 and 13.57 μmol/g, respectively. The MIPMs-Zn + MAA possessed the higher selectivity for DMMP as shown by the isotherm binding test. These results revealed that the MIPMs-Zn + MAA had highly specific binding sites because they were assembled by the two functional monomers, vinyl-substituted Zn(ii) porphyrin and MAA, which coordinated to achieve specific binding with DMMP.
    Type of Medium: Online Resource
    ISSN: 0954-0083 , 1361-6412
    URL: Article
    DOI: 10.1177/0954008313485766
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2013
    detail.hit.zdb_id: 1483713-4
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  • 7
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    Maternal Passive Smoking During Pregnancy and Age of Menarche in Daughters : A Study of Elementary and Middle School Students in Shanghai
    SAGE Publications ; 2015
    In:  Asia Pacific Journal of Public Health Vol. 27, No. 2_suppl ( 2015-03), p. 14S-20S
    Details
    In: Asia Pacific Journal of Public Health, SAGE Publications, Vol. 27, No. 2_suppl ( 2015-03), p. 14S-20S
    Abstract: The objective of this study was to estimate the prevalence and determinants of passive smoking in pregnancy and to examine its association with an earlier age of menarche in offspring. This retrospective study enrolled 751 students 8 to 20 years old in Shanghai selected by stratified cluster sampling. Data were obtained through structured self-administered questionnaires and physical examinations. It was found that daughters with maternal tobacco exposure experienced relatively earlier menarche and had shorter cycle lengths, although both findings were not statistically significant. The unadjusted odds ratio for prenatal tobacco smoke exposure on the relatively earlier onset of menarche was 1.84 (95% confidence interval = 1.05-3.22) compared with no exposure, and the associations remained statistically significant after adjusting for birth weight, birth length, maternal age of menarche, and present height and weight. In conclusion, our study provides limited evidence supporting the hypothesis that maternal passive smoking during pregnancy leads to an earlier age of menarche of daughters.
    Type of Medium: Online Resource
    ISSN: 1010-5395 , 1941-2479
    URL: Article
    DOI: 10.1177/1010539515571581
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2015
    detail.hit.zdb_id: 2394975-2
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  • 8
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    Characteristics and trends of globally registered glioma clinical trials in the past 16 years
    SAGE Publications ; 2022
    In:  Therapeutic Advances in Neurological Disorders Vol. 15 ( 2022-01), p. 175628642211143-
    Details
    In: Therapeutic Advances in Neurological Disorders, SAGE Publications, Vol. 15 ( 2022-01), p. 175628642211143-
    Abstract: Advancement in the treatment of glioma has been vacant since temozolomide has proved its therapeutic value in glioblastoma in 2005. Aim: To help investigators understand the landscape of glioma clinical research, we analyzed the characteristics and trends of globally registered glioma trials in the past decades. Methods: This is a cross-sectional analysis of glioma trials registered on ClinicalTrials.gov between January 2006 and December 2021. Characteristics regarding phase, enrollment number, study design and type, funding source, tumor site, pathology, patient status, age of population, trial purpose, and participating country were abstracted, and chronological shifts were analyzed. Results: There were 1531 registered glioma trials involved 58 participating countries. The trial purpose concerning surgery, radiotherapy, chemotherapy, targeted therapy, tumor-treating fields, immunotherapy, other antiglioma therapy and non-antiglioma research trial accounts for 3.5%, 6.5%, 9.5%, 28.9%, 2.0%, 16.4%, 12.5%, and 20.6%, respectively. In the past 16 years, the numbers of chemotherapy and targeted therapy trials declined; tumor-treating fields and immune checkpoint inhibitor application trials sprang at the latter half period; Immunotherapy, other antiglioma therapy and non-antiglioma research trials escalated (all above p trend   〈  0.005). The trend also showed the phased trials registered diminishingly and that the trials which focused on glioblastoma registered incrementally (those two p trend   〈  0.05). Among 784 drug therapy trials, it was included 45 cytotoxic drugs, 186 targeted drugs, 19 immune checkpoint inhibitors, 78 other drugs, and five immunomodulatory drugs. Two trials belonged to Bayesian adaptive randomized design. By the end of December 2021, 309 trials had publications. Only everolimus and tumor-treating fields exhibited meaningful survival benefit in specific glioma patients in phase 3 trials. Conclusion: Meaningful effective treatments regarding drugs or methods for glioma were difficult to be found. Bayesian adaptive platform trials may accelerate clinical research in glioma. Development of novel treatment modalities for glioma is still challenged.
    Type of Medium: Online Resource
    ISSN: 1756-2864 , 1756-2864
    URL: Article
    DOI: 10.1177/17562864221114355
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2022
    detail.hit.zdb_id: 2442245-9
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  • 9
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    Do all patients with advanced N-stage nasopharyngeal carcinoma benefit from the addition of induction chemotherapy to concurrent chemoradiotherapy?
    SAGE Publications ; 2019
    In:  Therapeutic Advances in Medical Oncology Vol. 11 ( 2019-01), p. 175883591983386-
    Details
    In: Therapeutic Advances in Medical Oncology, SAGE Publications, Vol. 11 ( 2019-01), p. 175883591983386-
    Abstract: The aim of this study was to evaluate the benefits from the addition of induction chemotherapy (IC) to concurrent chemoradiotherapy (CCRT) in N2-3 nasopharyngeal carcinoma (NPC). Methods: A total of 3089 patients with nonmetastatic NPC, staged as N2-3 were retrospectively reviewed. IC contained cisplatin (80 mg/m 2 ) with 5-fluorouracil (800 mg/m 2 /day over 120 h), or cisplatin (80 mg/m 2 ) with docetaxel (80 mg/m 2 ), or cisplatin (60 mg/m 2 ) with 5-fluorouracil (600 mg/m 2 over 120 h), and docetaxel (60 mg/m 2 ) administered at 3-week intervals for two or three cycles. Concurrent chemotherapy consisted of cisplatin (80 or 100 mg/m 2 ) given in weeks 1, 4, and 7 of radiotherapy, or cisplatin (40 mg/m 2 ) given weekly during radiotherapy. Overall, three well-matched risk groups (low, intermediate, and high risk) were created using propensity score matching, and IC plus CCRT was compared with CCRT in each risk group. Our primary endpoint was distant metastasis-free survival (DMFS). Results: A nomogram for DMFS was established with good prognostic accuracy (C-index, 0.69; 95% confidence interval, 0.64–0.73). The survival curves for low, intermediate, and high-risk groups stratified by the nomogram were significantly different between all three risk groups, with corresponding 5-year DMFS rates of 90.7%, 79.4%, and 64.9%, respectively ( p 〈 0.001). IC plus CCRT was significantly associated with superior DMFS as compared with CCRT alone (69.5% versus 56.7%, p = 0.004) in the high-risk group. However, no significant difference between IC plus CCRT and CCRT was observed ( p = 0.831 and 0.608, respectively) in the intermediate and low-risk groups. Conclusions: Our findings can help accurately guide the treatment of individual patients with advanced N-stage NPC.
    Type of Medium: Online Resource
    ISSN: 1758-8359 , 1758-8359
    URL: Article
    DOI: 10.1177/1758835919833863
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2019
    detail.hit.zdb_id: 2503443-1
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  • 10
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    Safety and effectiveness of multi-antenna microwave ablation-oriented combined therapy for large hepatocellular carcinoma
    SAGE Publications ; 2019
    In:  Therapeutic Advances in Gastroenterology Vol. 12 ( 2019-01), p. 175628481986296-
    Details
    In: Therapeutic Advances in Gastroenterology, SAGE Publications, Vol. 12 ( 2019-01), p. 175628481986296-
    Abstract: In patients with a large, unresectable hepatocellular carcinoma (HCC), the primary recommendation is for transarterial chemoembolization (TACE) but used alone TACE is not typically curative. Combinations of TACE followed in a delayed fashion by single-applicator thermal ablation have also been suboptimal. As an alternative, we investigated the combination of TACE followed within 1–3 days by multi-antenna microwave ablation (MWA) in patients with a large HCC, to determine the feasibility, safety, local control, and short-term survival rates of this approach. Methods: We retrospectively studied 43 patients with a large HCC (mean diameter, 8.8 cm; SD, 2.8 cm) treated between July 2015 and July 2018, who underwent TACE followed within 3 days by multi-antenna simultaneous MWA. We measured the liver and renal function before and after treatment, recorded complications, used three-dimensional software and imaging to calculate tumor necrosis rates at 1 month after therapy, and calculated overall survival (OS) and progression-free survival (PFS) using the Kaplan–Meier method. Results: Mean follow up was 12.2 (range, 3.5–35.6) months. All patients completed the treatment protocol. At 1 month after combined therapy, tumor necrosis was complete in 16 (37.2%), nearly complete in 19 (44.2%), and partial in 8 (18.6%) patients. The 1- and 2-year OS rates were 64.0% and 46.8%, respectively, with a median OS of 23.0 months; and the 1- and 2-year PFS rates were 19.9% and 4.4%, respectively, with a median PFS of 4.2 months. A transient change in liver function occurred 3 days after MWA but resolved within 1 month. Only two patients had major complications, which were treatable and resolved. Conclusion: Multi-antenna MWA-oriented combined therapy is feasible and well tolerated, and it results in satisfactory initial local control and short-term survival in some but not all patients with a large HCC.
    Type of Medium: Online Resource
    ISSN: 1756-2848 , 1756-2848
    URL: Article
    DOI: 10.1177/1756284819862966
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2019
    detail.hit.zdb_id: 2440710-0
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