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  • SAGE Publications  (6)
  • 1
    Online Resource
    Online Resource
    Research on cutting performance and fatigue life of conical pick in cutting rock process
    SAGE Publications ; 2021
    In:  Science Progress Vol. 104, No. 4 ( 2021-10)
    Details
    In: Science Progress, SAGE Publications, Vol. 104, No. 4 ( 2021-10)
    Abstract: The conical pick is the most crucial tool of roadheader for breaking rock, establishing the conical pick cutting rock and conical pick fatigue life numerical simulation models to investigate the influence of cutting parameters on rock damage, average peak cutting force, specific cutting energy and the conical pick fatigue life. The research results indicate that the width and depth of rock damage increase with increasing cutting depth and cutting speed. The average peak cutting force and the specific cutting energy have the same changing tendency. The changing trend of conical pick fatigue life and conical pick stress is opposite relationship. The optimum cutting angle of the conical pick cutting rock is 45°. Applying the research results for guiding the optimization of the cutting parameters reduces the specific cutting energy and stress and improves the conical pick fatigue life.
    Type of Medium: Online Resource
    ISSN: 0036-8504 , 2047-7163
    URL: Article
    DOI: 10.1177/00368504211050293
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2021
    detail.hit.zdb_id: 2483680-1
    detail.hit.zdb_id: 2199376-2
    SSG: 11
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    Online Resource
  • 2
    Online Resource
    Online Resource
    Rapid in situ cross-linking of hydrogel adhesives based on thiol-grafted bio-inspired catechol-conjugated chitosan
    SAGE Publications ; 2017
    In:  Journal of Biomaterials Applications Vol. 32, No. 5 ( 2017-11), p. 612-621
    Details
    In: Journal of Biomaterials Applications, SAGE Publications, Vol. 32, No. 5 ( 2017-11), p. 612-621
    Abstract: In this paper, a novel chitosan derivative, thiol-grafting bio-inspired catechol-conjugated chitosan was synthesized. The chemical structure of the synthesized catechol-conjugated chitosan was verified by 1 H NMR, and its contents of thiol group and catechol group were determined by UV-vis spectrum. Four percent of catechol-conjugated chitosan aqueous solution could form hydrogels rapidly in situ in 1 min or less with the addition of sodium periodate. Rheological studies showed that the mechanical properties depend on the concentrations of catechol-conjugated chitosan and the molar ratio of sodium periodate to catechol groups. Additionally, the adhesive properties of the resulting adhesives were evaluated, and the adhesion strength of obtained adhesives was as high as 50 kPa because of the complex and multiple interactions, especially the anti-oxidation mechanism of thiol group. The in vitro cytotoxicity assays demonstrated an excellent biocompatibility of the catechol-conjugated chitosan hydrogels. Benefiting from the in situ fast cured, desired mechanical strength, biocompatibility and relatively high adhesion performance, these properties suggested that catechol-conjugated chitosan hydrogel adhesives have potential applications as tissue adhesive for soft tissues.
    Type of Medium: Online Resource
    ISSN: 0885-3282 , 1530-8022
    URL: Article
    DOI: 10.1177/0885328217738403
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2017
    detail.hit.zdb_id: 2072559-0
    SSG: 12
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    Online Resource
  • 3
    Online Resource
    Online Resource
    Adaptive duty cycle control–based opportunistic routing scheme to reduce delay in cyber physical systems
    SAGE Publications ; 2019
    In:  International Journal of Distributed Sensor Networks Vol. 15, No. 4 ( 2019-04), p. 155014771984187-
    Details
    In: International Journal of Distributed Sensor Networks, SAGE Publications, Vol. 15, No. 4 ( 2019-04), p. 155014771984187-
    Type of Medium: Online Resource
    ISSN: 1550-1477 , 1550-1477
    URL: Article
    DOI: 10.1177/1550147719841870
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2019
    detail.hit.zdb_id: 2192922-1
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  • 4
    Online Resource
    Online Resource
    Research on Cutting Performance of Conical Pick Cutting Rock Plate with One Side Constrain and Three Sides Free
    SAGE Publications ; 2022
    In:  Science Progress Vol. 105, No. 1 ( 2022-01), p. 003685042210791-
    Details
    In: Science Progress, SAGE Publications, Vol. 105, No. 1 ( 2022-01), p. 003685042210791-
    Abstract: To improve the conical pick cutting performance by per cutting to the free surface. The cutting performance of rock and rock plate breaking are investigated by theoretical and experimental methods. Analyzed the fracture position of the rock plate with constrained one side by the pick to study the effect of rock properties and the rock plate structural parameters on cutting force. The results indicated that the rock plate fracture is mainly from the constrained side and center of the rock plate. The cutting force of the conical pick is significantly affected by the rock plate structural parameters and the constraint sides of the rock plate number. The cutting force increases obviously with the increase of plate thickness, cutting point depth, and the rock uniaxial compressive strength. However, the influence of rock plate constrains sides number is opposite. It provides a basis for improving the cutting performance of pick and predicting the rock plate fracture.
    Type of Medium: Online Resource
    ISSN: 0036-8504 , 2047-7163
    URL: Article
    DOI: 10.1177/00368504221079191
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2022
    detail.hit.zdb_id: 2483680-1
    detail.hit.zdb_id: 2199376-2
    SSG: 11
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  • 5
    Online Resource
    Online Resource
    Poly (L-Lactic Acid) Porous Scaffold-Supported Alginate Hydrogel with Improved Mechanical Properties and Biocompatibility
    SAGE Publications ; 2016
    In:  The International Journal of Artificial Organs Vol. 39, No. 8 ( 2016-08), p. 435-443
    Details
    In: The International Journal of Artificial Organs, SAGE Publications, Vol. 39, No. 8 ( 2016-08), p. 435-443
    Abstract: Polymer porous scaffolds and hydrogels have been separately employed and explored for a wide range of applications including cell encapsulation, drug delivery, and tissue engineering. Methods In this study, a three-dimensional poly (L-lactic acid) (PLLA) scaffold with interconnected and homogeneously distributed pores was fabricated to support the alginate hydrogel (Alg). The gels were filled into the porous scaffold, which acted as an analogue of native extracellular matrix (ECM) for entrapment of cells within a support of predefined shape. The mechanical strength of the composite scaffold was characterized by compression testing. The chondrocyte behavior in the scaffold was determined by inverted microscopy, scanning electron microscopy (SEM) and MTT viability assay. The repair efficiency of such a composite scaffold was further investigated in dog spinal defects by histological evaluation after implantation for 4 weeks. Results Results showed that the composite scaffold possessed superior mechanical properties and hierarchical porous structure in comparison to pure Alg. Cell culture revealed that the cells presented a specific cartilage status in the composite scaffold in line with higher adherence and proliferation ratio. The histological analyses suggested that the composite scaffold substantially promotes its integration in the host tissue accompanied with a low inflammatory reaction and new tissue formation. Conclusions The method thus provides a useful pathway for scaffold preparation that can simultaneously achieve suitable mechanical properties and good biocompatibility.
    Type of Medium: Online Resource
    ISSN: 0391-3988 , 1724-6040
    URL: Article
    DOI: 10.5301/ijao.5000516
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2016
    detail.hit.zdb_id: 1474999-3
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  • 6
    Online Resource
    Online Resource
    Clinical Efficacy of HiPorfin Photodynamic Therapy for Advanced Obstructive Esophageal Cancer
    SAGE Publications ; 2020
    In:  Technology in Cancer Research & Treatment Vol. 19 ( 2020-01-01), p. 153303382093033-
    Details
    In: Technology in Cancer Research & Treatment, SAGE Publications, Vol. 19 ( 2020-01-01), p. 153303382093033-
    Abstract: To explore the clinical efficacy of HiPorfin photodynamic therapy for advanced esophageal cancer and evaluate its impact on survival. Methods: Retrospective analysis of 32 patients with advanced obstructive esophageal cancer at our institution from September 2013 to December 2016. HiPorfin was infused as the photosensitizer at a dose of 5 mg/kg, and after 48 hours, 630-nm laser irradiation was subsequently performed through an optical fiber that passed through the biopsy channel of a flexible endoscope. Results: The effectiveness rate was 78.1% (25/32), and the significant efficacy rate was 56.3% (18/32). The dysphagia score decreased from 3.43 ± 0.73 to 1.79 ± 0.53 ( P 〈 .05). There was no grade 3 or more toxicity. The median overall survival was estimated to be 16 months. Univariate analysis showed higher overall survival with a Karnofsky Performance Status score ≥80 compared with a Karnofsky Performance Status score 〈 80 (hazard ratio: 2.626; 95% CI: 1.091-6.322; P = .024). Overall survival was higher in patients who had received radiation therapy than in patients who did not receive radiation therapy (hazard ratio: 3.574; 95% CI: 1.501-8.510; P = .002). Conclusion: Photodynamic therapy is an effective method for advanced esophageal cancer. The side effects are mild, and the short-term effect is good, especially in the relief of dysphagia. Photodynamic therapy can prolong the survival of patients with advanced esophageal cancer, and the Karnofsky Performance Status score and previous radiation therapy have a significant effect on the overall survival.
    Type of Medium: Online Resource
    ISSN: 1533-0346 , 1533-0338
    URL: Article
    DOI: 10.1177/1533033820930335
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2020
    detail.hit.zdb_id: 2146365-7
    detail.hit.zdb_id: 2220436-2
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