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  • SAGE Publications  (14)
  • 1
    Online Resource
    Online Resource
    Letter to the Editor Regarding “Intersphincteric Resection Versus Abdominoperineal Resection for Low Rectal Cancer: A Meta-Analysis”
    SAGE Publications ; 2022
    In:  Surgical Innovation Vol. 29, No. 3 ( 2022-06), p. 470-471
    Details
    In: Surgical Innovation, SAGE Publications, Vol. 29, No. 3 ( 2022-06), p. 470-471
    Type of Medium: Online Resource
    ISSN: 1553-3506 , 1553-3514
    URL: Article
    DOI: 10.1177/15533506211053680
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2022
    detail.hit.zdb_id: 2233576-6
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  • 2
    Online Resource
    Online Resource
    Electroacupuncture exerts an anti-migraine effect via modulation of the 5-HT7 receptor in the conscious rat
    SAGE Publications ; 2019
    In:  Acupuncture in Medicine Vol. 37, No. 1 ( 2019-02), p. 47-54
    Details
    In: Acupuncture in Medicine, SAGE Publications, Vol. 37, No. 1 ( 2019-02), p. 47-54
    Abstract: Acupuncture has been recommended as an alternative therapy for migraine. Emerging evidence suggests that the 5-HT 7 receptor (5-HT 7 R) plays a significant facilitatory role in descending modulation in migraine pathophysiology, and that activation of 5-HT 7 R in the descending pathway is involved in migraine central sensitisation. Objective: To investigate the ability of electroacupuncture (EA) to ameliorate central sensitisation via modulation of 5-HT 7 R in the descending pain pathways using a rat model of migraine induced by repetitive dural electrical stimulation (DES). Design: 64 male Sprague-Dawley rats were randomly divided into four groups: Normal group; DES group (receiving dural electrical stimulation only); DES+GB20 group (DES model group treated with EA at GB20); and DES+Sham group (DES model group treated with EA at a non-traditional (sham) acupuncture point). The presence of cutaneous allodynia was determined by measuring facial and hind-paw withdrawal latencies to electronic von-Frey. The expression of 5-HT 7 R in the descending pathways (periaqueductal grey, raphe magnus nucleus, and trigeminal nucleus caudalis) was assessed using immunofluorescence and Western blotting. Results: Facial and hind-paw withdrawal thresholds were significantly increased in the DES+GB20 group compared with the untreated DES group. The expression of 5-HT 7 R was significantly decreased in the DES+GB20 group compared with the DES group (one-way analysis of variance (ANOVA), P 〈 0.05). No significant differences in behaviour or expression were found between the rats in the DES+Sham group and the untreated DES group (one-way ANOVA, P 〉 0.05). Conclusion: EA at GB20 may ameliorate central sensitisation in migraine by inhibiting the activation of 5-HT 7 receptors in the descending pain pathway in a rat model of migraine.
    Type of Medium: Online Resource
    ISSN: 0964-5284 , 1759-9873
    URL: Article
    DOI: 10.1136/acupmed-2017-011410
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2019
    detail.hit.zdb_id: 2126127-1
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  • 3
    Online Resource
    Online Resource
    From fundamental study to practical application of kerosene in compression ignition engines: An experimental and modeling review
    SAGE Publications ; 2020
    In:  Proceedings of the Institution of Mechanical Engineers, Part D: Journal of Automobile Engineering Vol. 234, No. 2-3 ( 2020-02), p. 303-333
    Details
    In: Proceedings of the Institution of Mechanical Engineers, Part D: Journal of Automobile Engineering, SAGE Publications, Vol. 234, No. 2-3 ( 2020-02), p. 303-333
    Abstract: The use of kerosene in direct injection compression ignition engines is fundamentally due to the introduction of the Single Fuel Concept. As conventional direct injection compression ignition diesel engines are made specifically to use diesel fuel, the usage of kerosene will affect engine emissions and performance due to differences between the fuel properties of kerosene and diesel. As a result, in order for kerosene to be properly and efficiently used in diesel engines, it is needful for the scientific community to know the properties of kerosene, its autoignition and combustion characteristics, as well as its emissions formation behavior under diesel engine operating conditions. Moreover, it is desirable to know the progress made in the development of suitable kerosene surrogates for engine applications as it is a crucial step toward the development of reliable chemical reaction mechanisms for numerical simulations. Therefore, in this work, a comprehensive review is carried out systematically to better understand the characteristics and behavior of kerosene under direct injection compression ignition engine relevant conditions. In this review work, the fuel properties of kerosene are summarized and discussed. In addition, fundamental autoignition studies of kerosene in shock tube, rapid compression machine, fuel ignition tester, ignition quality tester, constant volume combustion chamber, and engine are compiled and evaluated. Furthermore, experimental studies of kerosene spray and combustion in constant volume combustion chambers are examined. Also, the experimental investigations of kerosene combustion and emissions in direct injection compression ignition engines are discussed. Moreover, the development of kerosene surrogates, their chemical reaction mechanisms, and the modeling of kerosene combustion in direct injection compression ignition engines are summarized and talked about. Finally, recommendations are also given to help researchers focus on the areas which are still severely lacking.
    Type of Medium: Online Resource
    ISSN: 0954-4070 , 2041-2991
    URL: Article
    DOI: 10.1177/0954407019841218
    RVK:
    ZO 4200
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2020
    detail.hit.zdb_id: 2032754-7
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  • 4
    Online Resource
    Online Resource
    Research on the braking energy reuse management strategy of hybrid electric mining trucks based on motor load rate
    SAGE Publications ; 2023
    In:  Proceedings of the Institution of Mechanical Engineers, Part D: Journal of Automobile Engineering
    Details
    In: Proceedings of the Institution of Mechanical Engineers, Part D: Journal of Automobile Engineering, SAGE Publications
    Abstract: The braking energy recovery and reuse technology are significant to the energy-saving and emission reduction of hybrid mining dump trucks. Therefore, this paper proposes a technical scheme to increase the speed of the heavy-load uphill section by using the light overload of the motor. By constructing the vehicle dynamics model of the mining dump truck and the electric drive system component efficiency and engine energy consumption model and taking the “feedback braking energy-saving coefficient” as the evaluation index, the electric motors of each slope section under the rule-based energy management strategy are obtained. Then, the dynamic programing algorithm is used to optimize the selection of the motor load rate on the slope section. The results show that: on the premise of ensuring the dynamic performance of the vehicle, maximizing the use of the braking energy can shorten the driving time by 57.8 s and reduce the engine energy consumption 18.63 kWh, accounting for 8.56% of the engine energy consumption of the entire heavy-load uphill section. This paper provides a theoretical reference for the energy-saving research on the efficient reuse of braking energy of mining dump trucks on slopes.
    Type of Medium: Online Resource
    ISSN: 0954-4070 , 2041-2991
    URL: Article
    DOI: 10.1177/09544070231155706
    RVK:
    ZO 4200
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2023
    detail.hit.zdb_id: 2032754-7
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  • 5
    Online Resource
    Online Resource
    Spatiotemporal Heterogeneity of Carbon Dioxide Emissions: Evidence from High-Speed Railway Operations in China
    SAGE Publications ; 2023
    In:  Transportation Research Record: Journal of the Transportation Research Board
    Details
    In: Transportation Research Record: Journal of the Transportation Research Board, SAGE Publications
    Abstract: Carbon dioxide (CO 2 ) emissions reduction has become an ever-growing concern in China and the government has proposed the goals of carbon peak and carbon neutrality. To better address this concern, this work pays particular attention to high-speed railway (HSR) operations and examines their spatiotemporal effects and potential mechanism on CO 2 emissions. Using a geographically and temporally weighted regression (GTWR) model to fit a balanced panel dataset from the period 2008 to 2018, we have the following main findings. First, the GTWR model performs better than the pooled panel regression model as it considers temporal and spatial variations in factors of CO 2 emissions simultaneously. Second, the temporally varying coefficients of HSR operations indicate their consistent contributions to emissions reduction, suggesting that the national development of HSRs can provide significant emissions reduction benefits. Third, as revealed by the spatially varying coefficients of HSR operations, most provinces can mitigate CO 2 emissions by promoting HSRs, particularly in Shanxi, Hebei, and Shaanxi, owing to the larger contributions of HSR operations to CO 2 emissions reduction. Finally, the contributions of HSR operations to emissions reduction can be transmitted through the mechanism of technological progress. These findings can offer valuable insights into cross-collaborative and province-specific policymaking for mitigating CO 2 emissions.
    Type of Medium: Online Resource
    ISSN: 0361-1981 , 2169-4052
    URL: Article
    DOI: 10.1177/03611981231214522
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2023
    detail.hit.zdb_id: 2403378-9
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  • 6
    Online Resource
    Online Resource
    The Orientational Order of the α-Helical Backbone of Poly(γ-Benzyl L-Glutamate) – a Molecular Dynamics Simulation
    SAGE Publications ; 2015
    In:  Polymers and Polymer Composites Vol. 23, No. 1 ( 2015-01), p. 51-58
    Details
    In: Polymers and Polymer Composites, SAGE Publications, Vol. 23, No. 1 ( 2015-01), p. 51-58
    Abstract: For a Poly(γ-benzyl L-glutamate) (PBLG) segment with 30 monomers, molecular dynamics simulation was carry out in the Amber forcefield, by the software package InsightII/Discover. The geometrical structure of the backbone of the model molecule in the minimized energy state is in close agreement with that in the solid polypeptides. In the dynamic equilibrium state, the structure becomes slightly flabby and has a potential ca. 4800kJ/mol higher than that in the minimized energy state for the model molecule. On the average, the α-helical backbone architecture of PBLG remains quite stable during the molecular dynamic process, though the fluctuation of the bond and dihedral angles. The observed D NMR spectra for the quadrupolar splittings are reproduced and the previous architecture analysis was verified by the simulation calculations.
    Type of Medium: Online Resource
    ISSN: 0967-3911 , 1478-2391
    URL: Article
    DOI: 10.1177/096739111502300107
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2015
    detail.hit.zdb_id: 2099644-5
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  • 7
    Online Resource
    Online Resource
    Intersection-Aware Channel Assignment and Routing in Multi-Channel Multi-Hop Wireless Networks with a Single Transceiver
    SAGE Publications ; 2009
    In:  International Journal of Distributed Sensor Networks Vol. 5, No. 1 ( 2009-01-01), p. 25-25
    Details
    In: International Journal of Distributed Sensor Networks, SAGE Publications, Vol. 5, No. 1 ( 2009-01-01), p. 25-25
    Abstract: This article proposes an intersection-aware channel assignment and routing protocol for wireless ad hoc networks with a single transceiver. This protocol increases the network capacity of an IEEE 802.11 network by exploiting frequency diversity. Using the proposed protocol, multiple communications can simultaneously take place in a region without interfering with each other. However, it must avoid a multi-channel hidden terminal problem for designing channel assignment and routing protocol. This paper considers issues regarding multiple channels at the network layer, assuming a single channel MAC protocol such as IEEE 802.11 DCF. Also, the proposed protocol assumes that each node in the network is equipped with a single transceiver. This set of assumptions is very practical, because most devices have a single wireless card implementing the IEEE 802.11 DCF protocol. Each node uses modular exponentiation congruence to represent the channel schedule, which assures that each pair of nodes has common channels for communication in every cycle. Each node switches across channels in such a manner that each pair of nodes works on the same channel when they desire to communicate; otherwise they work on a different channel, and hence do not interfere with each other. However, for the intersecting node, there is no benefit in using single radio multiple channels since the capacity around the intersection node can at most be O (W), W is the link capacity, regardless of the number of channels. The protocol lets the intersecting node always work on the same channel whereas the nonintersecting node can work on different channels. The two states for every node in the network are the state of an intersecting node and the state of non-intersecting node. Using the proposed protocol, nodes discover multiple routes to the destination node; the node selects the path with most intersecting nodes to avoid more nodes become intersecting nodes when the number of flows increases greatly. Once a node becomes an intersecting node, it will work on the same channel in a cycle. Simulation results show that the proposed protocol significantly increases the aggregate end-to-end throughput and network capacity greatly over a single-channel protocol and some other channel assignment and routing protocols in several wireless networking scenarios.
    Type of Medium: Online Resource
    ISSN: 1550-1477 , 1550-1477
    URL: Article
    DOI: 10.1080/15501320802520563
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2009
    detail.hit.zdb_id: 2192922-1
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  • 8
    Online Resource
    Online Resource
    Magnetic levitation force exerted on the cylindrical magnet in a ferrofluid damper
    SAGE Publications ; 2017
    In:  Journal of Vibration and Control Vol. 23, No. 14 ( 2017-08), p. 2345-2354
    Details
    In: Journal of Vibration and Control, SAGE Publications, Vol. 23, No. 14 ( 2017-08), p. 2345-2354
    Abstract: The levitation phenomenon of permanent magnets immersed in ferrofluid is the foundation of ferrofluid dampers. According to the model built using bipolar coordinates, the analytical equation describing the force exerted on the cylindrical magnets in ferrofluid dampers is obtained, which is different from that of the previous results. The analysis of the equation indicates that the magnetic levitation force increases with the eccentricity of the magnet, the radius of the magnet and the permeability of ferrofluid, respectively, when other factors are definite. As a result, we can increase the permeability of ferrofluid and decrease the radius ratio of the magnet and the tube to enhance the levitation stability.
    Type of Medium: Online Resource
    ISSN: 1077-5463 , 1741-2986
    URL: Article
    DOI: 10.1177/1077546315616516
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2017
    detail.hit.zdb_id: 2070247-4
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  • 9
    Online Resource
    Online Resource
    Neural Progenitor Cells Generate Motoneuron-Like Cells to Form Functional Connections with Target Muscles after Transplantation into the Musculocutaneous Nerve
    SAGE Publications ; 2012
    In:  Cell Transplantation Vol. 21, No. 12 ( 2012-12), p. 2651-2663
    Details
    In: Cell Transplantation, SAGE Publications, Vol. 21, No. 12 ( 2012-12), p. 2651-2663
    Abstract: Neural progenitor cells (NPCs) are suggested to be a valuable source of cell transplant in treatment of various neurological diseases because of their distinct attributes. They can be expanded and induced to differentiate in vitro. However, it remains uncertain whether in vitro expanded NPCs have the capacity to give rise to functional motoneurons after transplantation in vivo. Here, we showed that in vitro expanded NPCs, when transplanted into the musculocutaneous nerve, generated motoneuron-like cells that exhibited typical morphology with large cell bodies, expressed specific molecules, and extended axons to form functional connections with the target muscle. In contrast, transplanted NPCs failed to yield motoneurons in the injured ventral horn of the spinal cord. The results of the study demonstrate that NPCs have the potential to generate functional motoneurons in an appropriate environment. The distinct differentiating fate of NPCs in the musculocutaneous nerve and the injured ventral horn suggests the importance and necessity of modifying the host microenvironment in use of NPCs for cell replacement therapies for motoneuron diseases.
    Type of Medium: Online Resource
    ISSN: 0963-6897 , 1555-3892
    URL: Article
    DOI: 10.3727/096368912X654975
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2012
    detail.hit.zdb_id: 2020466-8
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  • 10
    Online Resource
    Online Resource
    Enabling robust simulation of polyoxymethylene dimethyl ether 3 (PODE 3 ) combustion in engines
    SAGE Publications ; 2022
    In:  International Journal of Engine Research Vol. 23, No. 9 ( 2022-09), p. 1522-1542
    Details
    In: International Journal of Engine Research, SAGE Publications, Vol. 23, No. 9 ( 2022-09), p. 1522-1542
    Abstract: PODE 3 reaction mechanism developments are still in the early stages with very limited research. In particular, reaction mechanisms to characterize PODE 3 combustion are neither sufficiently compact nor robust for 3D numerical simulations. Hence, the current work seeks to develop a compact yet reliable PODE 3 reaction mechanism, embedded with appropriate chemistry to describe polycyclic aromatic hydrocarbon reactions. A decoupling methodology has been employed to achieve the desired outcome. The final mechanism comprises only 120 species and 560 reactions even after including components of diesel and gasoline surrogates. It has been validated with ignition delay times, laminar flame speeds, jet-stirred reactor species concentration profiles, flame species concentration profiles, extinction strain rates, heat release rates in constant volume combustion chamber, homogeneous charge compression ignition engine combustion, and direct injection compression ignition engine combustion. In a numerical investigation conducted using gasoline/diesel/PODE 3 blends, soot emissions are observed to decrease with PODE 3 increment, which establishes PODE 3 as a promising additive. Intriguingly, the current study has also discovered that with 15% PODE 3 addition, soot and its precursors will increase in concentration during combustion, though this effect will be outweighed by oxidative effects towards the end. Overall, the new mechanism has been proven suitable and feasible for engine simulations.
    Type of Medium: Online Resource
    ISSN: 1468-0874 , 2041-3149
    URL: Article
    DOI: 10.1177/14680874211018363
    RVK:
    ZG 1100
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2022
    detail.hit.zdb_id: 2030603-9
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