GLORIA

GEOMAR Library Ocean Research Information Access

X

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • SAGE Publications  (69)
Material
Publisher
  • SAGE Publications  (69)
Person/Organisation
Language
Years
FID
Subjects(RVK)
  • 1
    Online Resource
    Online Resource
    Chemokine CXCL1 in serum mediates the antinociceptive effect of manual acupuncture at ST36
    SAGE Publications ; 2021
    In:  Acupuncture in Medicine Vol. 39, No. 6 ( 2021-12), p. 673-680
    Details
    In: Acupuncture in Medicine, SAGE Publications, Vol. 39, No. 6 ( 2021-12), p. 673-680
    Abstract: Inflammatory pain is the most common type of pain encountered clinically. The analgesic effect of acupuncture has been well-documented. Objective: The aim of this study was to investigate the involvement of chemokine CXCL1 in the serum on manual acupuncture (MA)-induced antinociception. Methods: Rats with inflammatory pain of the right hind paw were induced by intraplantar (i.pl.) administration of complete Freund’s adjuvant (CFA). After wards, the CFA-injected rats were treated daily with MA at ST36 from Day 1 to Day 7, and thermal nociceptive thresholds (paw withdrawal latency; PWL) were analyzed. The concentration of CXCL1 in the serum of the rats was measured by enzyme-linked immunosorbent assay (ELISA) after the first and the last MA treatment. Subsequently, the rats were injected with two doses (5 or 10 μg) of recombinant CXCL1 through the tail vein daily from Day 1 to Day 7 or injected with two doses (6.4 or 16 μg) of anti-CXCL1 antibody using the same methods and course at 30 min before MA, and the PWLs were measured again. Finally, naloxone (500 μg, 0.1 mL) was administered by i.pl. injection into the inflamed paw 5 min before the last MA treatment or last injection of recombinant CXCL1. Results: MA significantly increased the PWLs and upregulated the expression of serum CXCL1 in the CFA-injected rats. Without acupuncture, repeated tail vein injection of recombinant CXCL1 showed an analgesic effect on CFA-induced inflammatory pain. Conversely, the neutralization of serum CXCL1 by anti-CXCL1 antibody decreased MA-induced antinociception in a time-dependent manner. Anti-CXCL1 antibody injected just once before the first MA did not affect MA-induced antinociception. The analgesic effects of MA and recombinant CXCL1 were reversed by an i.pl. injection of naloxone. Conclusion: This study indicates MA at ST36 had an analgesic effect on inflammatory pain and found a novel function of CXCL1. Increased serum CXCL1 had an antinociceptive effect on inflammatory pain induced by CFA. CXCL1 in serum appeared to be a key molecule involved in the peripheral mechanism of MA-induced antinociception. The analgesic effect of MA or recombinant CXCL1 on inflammatory pain might be mediated through a peripheral opioid pathway, which needs further investigation.
    Type of Medium: Online Resource
    ISSN: 0964-5284 , 1759-9873
    URL: Article
    DOI: 10.1177/0964528421997435
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2021
    detail.hit.zdb_id: 2126127-1
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 2
    Online Resource
    Online Resource
    Malignant Peripheral Nerve Sheath Tumor in the Nasal Cavity of a Neonate: A Case Report
    SAGE Publications ; 2023
    In:  Ear, Nose & Throat Journal Vol. 102, No. 10 ( 2023-10), p. NP527-NP533
    Details
    In: Ear, Nose & Throat Journal, SAGE Publications, Vol. 102, No. 10 ( 2023-10), p. NP527-NP533
    Abstract: Malignant peripheral nerve sheath tumor (MPNST) is a rare tumor that can develop on the lining of nerves and within the network of nerve fibers in different organs, and it is commonly found in the head and neck, limbs, and trunk. These tumors can occur in patients of any age. They most commonly occur in adults aged 20 to 50 years; however, fewer cases of this tumor in children have been reported. To date, no neonatal case of MPNST in the nasal cavity has been reported. Here, we report the case of a 4-day-old female newborn who presented with a nasal mass that re-enlarged after surgery and was diagnosed as MPNST of the nasal cavity on the basis of pathological results. This is the first report of MPNST in the nasal cavity of a neonate. Differential diagnosis and treatment of nasal masses have been proposed in the related literature.
    Type of Medium: Online Resource
    ISSN: 0145-5613 , 1942-7522
    URL: Article
    DOI: 10.1177/01455613211014103
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2023
    detail.hit.zdb_id: 2067528-8
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 3
    Online Resource
    Online Resource
    A novel combination of nano-scaffolds with micro-scaffolds to mimic extracellularmatrices improve osteogenesis
    SAGE Publications ; 2014
    In:  Journal of Biomaterials Applications Vol. 29, No. 1 ( 2014-07), p. 59-71
    Details
    In: Journal of Biomaterials Applications, SAGE Publications, Vol. 29, No. 1 ( 2014-07), p. 59-71
    Abstract: To improve bone engineering for clinical applications, we coupled nanofiber-peptide hydrogel to nano-hydroxyapatite/collagen to form a bioactive scaffold (cnHAC) that mimics extracellular matrices. In comparison to nano-hydroxyapatite/collagen, we found that cnHAC promoted cell adhesion and spreading, and DNA content measurements, alkaline phosphatase activity assays, and reverse transcriptase-polymerase chain reaction analyses of osteogenic gene expression showed that cnHAC significantly improved cellular attachment, proliferation, and osteogenic differentiation in vitro ( P  〈  0.05). In vivo models based on rat calvarial implants showed that cnHAC significantly enhanced bone regeneration ( P  〈  0.05). In conclusion, we demonstrated that novel cnHAC scaffolds could potentially facilitate future bone regenerative medicine.
    Type of Medium: Online Resource
    ISSN: 0885-3282 , 1530-8022
    URL: Article
    DOI: 10.1177/0885328213514467
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2014
    detail.hit.zdb_id: 2072559-0
    SSG: 12
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 4
    Online Resource
    Online Resource
    Antioxidative and Neuroprotective Effects of the Cytochalasans From Endophytes
    SAGE Publications ; 2020
    In:  Natural Product Communications Vol. 15, No. 4 ( 2020-04), p. 1934578X2091730-
    Details
    In: Natural Product Communications, SAGE Publications, Vol. 15, No. 4 ( 2020-04), p. 1934578X2091730-
    Abstract: Six 10-indolyl-cytochalasans, chaetoglobosin F (1), chaetoglobosin F ex (2), chaetoglobosin E (3), cytoglobosin A (4), penochalasin C (5), and isochaetoglobosin D (6), and 2 10-phenyl-cytochalasans, cytochalasin H (7) and 18-methoxycytochalasin J (8) were isolated from 2 plant endophytes, Chaetomiun globosum WQ and Phomopsis sp. IFB-E060, respectively. These cytochalasans were investigated with radical-scavenging activity assay and hydrogen peroxide (H 2 O 2 )/ N-methyl-4-phenylpyridinium iodide (MPP + )-induced pheochromocytoma cell line 12 (PC12) cell models, respectively. Results showed that 7 compounds had antioxidative effects except 5, with scavenging 2,2-diphenyl-1-picrylhydrazyl radical effect 1 = 6= 7 〉 2 〉 4 = 3 〉 8 and scavenging 2,2-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt radical effect 1 = 6 = 7 〉 2 〉 3 〉 8 〉 4. They could also inhibit H 2 O 2 /MPP + -induced damage in PC12 cells by increasing cell viability and decreasing lactate dehydrogenase release. Compounds 1, 6, and 7 exhibited the strongest antioxidative potencies, which are more potent than vitamin E. Additionally, antioxidative and neuroprotective effects of 1∼8 showed some structure–activity relationship. These findings would be useful for looking for cytochalasin-related new lead compounds or drugs to prevent and treat Parkinson’s disease.
    Type of Medium: Online Resource
    ISSN: 1934-578X , 1555-9475
    URL: Article
    DOI: 10.1177/1934578X20917308
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2020
    detail.hit.zdb_id: 2430442-6
    SSG: 15,3
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 5
    Online Resource
    Online Resource
    Prefrontal Cortical Control of Anxiety: Recent Advances
    SAGE Publications ; 2023
    In:  The Neuroscientist Vol. 29, No. 4 ( 2023-08), p. 488-505
    Details
    In: The Neuroscientist, SAGE Publications, Vol. 29, No. 4 ( 2023-08), p. 488-505
    Abstract: Dysfunction in the prefrontal cortex is commonly implicated in anxiety disorders, but the mechanisms remain unclear. Approach-avoidance conflict tasks have been extensively used in animal research to better understand how changes in neural activity within the prefrontal cortex contribute to avoidance behaviors, which are believed to play a major role in the maintenance of anxiety disorders. In this article, we first review studies utilizing in vivo electrophysiology to reveal the relationship between changes in neural activity and avoidance behavior in rodents. We then review recent studies that take advantage of optical and genetic techniques to test the unique contribution of specific prefrontal cortex circuits and cell types to the control of anxiety-related avoidance behaviors. This new body of work reveals that behavior during approach-avoidance conflict is dynamically modulated by individual cell types, distinct neural pathways, and specific oscillatory frequencies. The integration of these different pathways, particularly as mediated by interactions between excitatory and inhibitory neurons, represents an exciting opportunity for the future of understanding anxiety.
    Type of Medium: Online Resource
    ISSN: 1073-8584 , 1089-4098
    URL: Article
    DOI: 10.1177/10738584211069071
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2023
    detail.hit.zdb_id: 2029471-2
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 6
    Online Resource
    Online Resource
    Biodegradable poly(butylene-carbonate) porous membranes for guided bone regeneration: In vitro and in vivo studies
    SAGE Publications ; 2013
    In:  Journal of Bioactive and Compatible Polymers Vol. 28, No. 6 ( 2013-11), p. 621-636
    Details
    In: Journal of Bioactive and Compatible Polymers, SAGE Publications, Vol. 28, No. 6 ( 2013-11), p. 621-636
    Abstract: Poly(butylene-carbonate) is a potential alternative to poly(ε-caprolactone) for biomedical application. Although mechanical properties of porous poly(butylene-carbonate) membranes were inferior to poly(ε-caprolactone), its contact angles (47.41° ± 1.17°) were lower than poly(ε-caprolactone) (77.24° ± 0.54°) (p 〈 0.001). It degraded faster than poly(ε-caprolactone) during a 10-week in vitro experiment (p 〈 0.01). Moreover, it had excellent bioactivity during simulated body fluid immersion. Cell spreading on poly(butylene-carbonate) was better than that on poly(ε-caprolactone). Cell behavior tests including cytotoxicity, proliferation, and differentiation were performed. The poly(butylene-carbonate) is more compatible with cells and promotes cell differentiation. In vivo, the defects covered by poly(butylene-carbonate) and poly(ε-caprolactone) membranes had a similar degree of regeneration at 4 weeks. It was concluded that poly(butylene-carbonate) could potentially be used to guide bone regeneration, and it is a potential new biodegradable polymer.
    Type of Medium: Online Resource
    ISSN: 0883-9115 , 1530-8030
    URL: Article
    DOI: 10.1177/0883911513509471
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2013
    detail.hit.zdb_id: 2073790-7
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 7
    Online Resource
    Online Resource
    Specific Effects of Characteristics of Enriched Environment on Innovative Problem Solving by Animals
    SAGE Publications ; 2022
    In:  Psychological Science Vol. 33, No. 7 ( 2022-07), p. 1097-1111
    Details
    In: Psychological Science, SAGE Publications, Vol. 33, No. 7 ( 2022-07), p. 1097-1111
    Abstract: Numerous studies have revealed that an enriched environment can enhance the survival-related behaviors and brain functions of animals. However, the effects and specific roles of the enrichment characteristics on animals’ innovative capability, a cognitive ability crucial for survival in nature, are still not well known. In this study, we assigned mice to environment-manipulation groups ( n = 15 each) to investigate the specific effects of environmental novelty (novel vs. familiar) and environmental complexity (complex vs. normal) on innovative problem solving and its possible neural mechanisms. Results showed that mice in only the novel-environment group performed better at innovative-problem-solving tasks and showed greater numbers of novel explorations and dopaminergic projections from the ventral tegmental area to the nucleus accumbens in the brain. These findings indicate that an enriched environment has the potential to promote the innovative capability of mice by enhancing their novel exploratory motivation, which depends on the novelty of the environment but not its complexity.
    Type of Medium: Online Resource
    ISSN: 0956-7976 , 1467-9280
    URL: Article
    DOI: 10.1177/09567976211070562
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2022
    detail.hit.zdb_id: 2022256-7
    SSG: 5,2
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 8
    Online Resource
    Online Resource
    LncRNA BLACAT1 Promotes Proliferation, Migration and Invasion of Prostate Cancer Cells via Regulating miR-29a-3p/DVL3 Axis
    SAGE Publications ; 2021
    In:  Technology in Cancer Research & Treatment Vol. 20 ( 2021-01-01), p. 153303382097234-
    Details
    In: Technology in Cancer Research & Treatment, SAGE Publications, Vol. 20 ( 2021-01-01), p. 153303382097234-
    Abstract: Long non-coding RNA bladder cancer associated transcript 1 (BLACAT1) is oncogenic in several types of cancers. However, little is known concerning its expression and function in prostate cancer. Methods: Paired prostate cancer samples were collected, and the expression levels of BLACAT1, miR-29a-3p and disheveled segment polarity protein 3 (DVL3) were examined by quantitative real-time polymerase chain reaction (qRT-PCR); BLACAT1 shRNAs were transfected into PC-3 and LNCaP cell lines, and proliferative ability was detected by cell counting kit-8 (CCK-8) assay; qRT-PCR and Western blot were used to analyze the changes of miR-29a-3p and DVL3; dual-luciferase reporter gene assay was used to determine the regulatory relationships between miR-29a-3p and BLACAT1, and miR-29a-3p and DVL3. Results: BLACAT1 expression was significantly up-regulated in cancerous tissues of prostate cancer samples and positively correlated with the expression of DVL3, while negatively associated with miR-29a-3p. After the transfection of BLACAT1 shRNAs into prostate cancer cells, the proliferative ability and metastatic ability of cancer cells were significantly inhibited; BLACAT1 shRNAs could reduce the expression of DVL3 on both mRNA and protein expressions levels, the luciferase activity of BLACAT1 reporter was inhibited by miR-29a-3p, and DVL3 was validated as a target gene of miR-29a-3p. Conclusion: BLACAT1 expression is abnormally up-regulated in prostate cancer tissues. BLACAT1 can modulate the proliferative and metastatic ability of prostate cancer cells and have the potential to be the “ceRNA” to regulate the expression of DVL3 by sponging miR-29a-3p.
    Type of Medium: Online Resource
    ISSN: 1533-0346 , 1533-0338
    URL: Article
    DOI: 10.1177/1533033820972342
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2021
    detail.hit.zdb_id: 2146365-7
    detail.hit.zdb_id: 2220436-2
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 9
    Online Resource
    Online Resource
    MicroRNA-30a promotes invasiveness and metastasis in vitro and in vivo through epithelial–mesenchymal transition and results in poor survival of nasopharyngeal carcinoma patients
    SAGE Publications ; 2014
    In:  Experimental Biology and Medicine Vol. 239, No. 7 ( 2014-07), p. 891-898
    Details
    In: Experimental Biology and Medicine, SAGE Publications, Vol. 239, No. 7 ( 2014-07), p. 891-898
    Abstract: Although microRNA-30a (miR-30a) has been shown to regulate cancer metastasis, the molecular mechanism has not yet been clearly elucidated in nasopharyngeal carcinoma (NPC). The present study was to investigate the miR-30a expression pattern and its potential functions and further to identify its target gene and corresponding clinical applications in NPC. MiR-30a was identified to be down-regulated in NPC primary tumors compared with metastatic tumors using quantitative real-time PCR. Furthermore, over-expression of miR-30a transfected with precursor increased the ability of metastasis and invasion of NPC tumor cells in vivo and in vitro. E-cadherin was screened as a putative target gene of miR-30a by computational algorithms. Luciferase reporter assays showed that over-expression of miR-30a directly reduced the activity of a luciferase transcript combined with the 3′-untranslated region (3′-UTR) of E-cadherin. Kaplan–Meier survival analysis and log-rank test were analyzed for 1077 NPC patients for overall survival, indicating that a high expression of E-cadherin was beneficial for NPC prognosis ( P = 0.001). Importantly, NPC patients with high expression of E-cadherin had much lower risk of poor prognosis (hazard ratio = 0.757, P = 0.017) using multivariate analysis. In conclusion, miR-30a could play an important role in regulating NPC metastasis and potentially provide useful guidelines for individualized therapy.
    Type of Medium: Online Resource
    ISSN: 1535-3702 , 1535-3699
    URL: Article
    DOI: 10.1177/1535370214532758
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2014
    detail.hit.zdb_id: 2020856-X
    SSG: 12
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 10
    Online Resource
    Online Resource
    Timing and duration of the East Asian summer monsoon maximum during the Holocene based on stalagmite data from North China
    SAGE Publications ; 2018
    In:  The Holocene Vol. 28, No. 10 ( 2018-10), p. 1631-1641
    Details
    In: The Holocene, SAGE Publications, Vol. 28, No. 10 ( 2018-10), p. 1631-1641
    Abstract: We present a continuous C-O isotope series that shows the detailed variability of East Asian summer monsoon (EASM) since 11.0 ka BP. The series is based on two stalagmites, namely, DSY1 and LM2, which were, respectively, obtained from Dongshiya and Laomu caves. The δ 18 O profiles of stalagmite excurse negatively in early Holocene and gradually become positive after around 6.9 ka BP, tracking the change in Northern Hemisphere summer insolation. Moreover, the ‘early-Holocene maximum’ supported by stalagmite δ 18 O records differs from the ‘mid-Holocene maximum’ indicated by geological archives, such as lake sediments and loess. This difference may be caused by different definition indicators of monsoon intensity. Stalagmite δ 18 O is relative to EASM intensity, but irrelative to precipitation in the East Asian monsoon region. The time intervals of EASM maximum and Holocene climatic optimum are desynchronized, which is confirmed by the variation in the stalagmite δ 13 C series. Stalagmite δ 13 C and δ 18 O have different variation tendencies. The tendency of δ 13 C in early mid-Holocene was generally light, but it was discontinuity and disrupted by rapid positive shift between 8.2 and 7.7 ka BP. We conclude that a rapid shift of about 8 ka BP is a turning point, before and after which δ 13 C acquires different controlling factors. Stalagmite δ 13 C showed no signs of positive excurse in late Holocene but it exhibited another characteristic, namely, millennial time scale oscillations. The few changes in stalagmite δ 13 C is attributed to weakened insolation during summer in the northern hemisphere, which leads to low evaporation rate, thereby modulating effective humidity change. The edge of the seasonal monsoonal front in northern China during monsoon recession is sensitive to the rain belt and causes the δ 13 C of the stalagmite to fluctuate greatly. This phenomenon shows that the climate in the study area is unstable in the late Holocene
    Type of Medium: Online Resource
    ISSN: 0959-6836 , 1477-0911
    URL: Article
    DOI: 10.1177/0959683618782606
    RVK:
    RA 1000
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2018
    detail.hit.zdb_id: 2027956-5
    SSG: 14
    SSG: 3,4
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...