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  • SAGE Publications  (88)
  • 1
    Online Resource
    Online Resource
    The single-monitor trial: an embedded CADe system increased adenoma detection during colonoscopy: a prospective randomized study
    SAGE Publications ; 2020
    In:  Therapeutic Advances in Gastroenterology Vol. 13 ( 2020-01), p. 175628482097916-
    Details
    In: Therapeutic Advances in Gastroenterology, SAGE Publications, Vol. 13 ( 2020-01), p. 175628482097916-
    Abstract: Computer-aided detection (CADe) of colon polyps has been demonstrated to improve colon polyp and adenoma detection during colonoscopy by indicating the location of a given polyp on a parallel monitor. The aim of this study was to investigate whether embedding the CADe system into the primary colonoscopy monitor may serve to increase polyp and adenoma detection, without increasing physician fatigue level. Methods: Consecutive patients presenting for colonoscopies were prospectively randomized to undergo routine colonoscopy with or without the assistance of a real-time polyp detection CADe system. Fatigue level was evaluated from score 0 to 10 by the performing endoscopists after each colonoscopy procedure. The main outcome was adenoma detection rate (ADR). Results: Out of 790 patients analyzed, 397 were randomized to routine colonoscopy (control group), and 393 to a colonoscopy with computer-aided diagnosis (CADe group). The ADRs were 20.91% and 29.01%, respectively (OR = 1.546, 95% CI 1.116–2.141, p = 0.009). The average number of adenomas per colonoscopy (APC) was 0.29 and 0.48, respectively (Change Folds = 1.64, 95% CI 1.299–2.063, p  〈  0.001). The improvement in polyp detection was mainly due to increased detection of non-advanced diminutive adenomas, serrated adenoma and hyperplastic polyps. The fatigue score for each procedure was 3.28 versus 3.40 for routine and CADe group, p = 0.357. Conclusions: A real-time CADe system employed on the primary endoscopy monitor may lead to improvements in ADR and polyp detection rate without increasing fatigue level during colonoscopy. The integration of a low-latency and high-performance CADe systems may serve as an effective quality assurance tool during colonoscopy. www.chictr.org.cn number, ChiCTR1800018058.
    Type of Medium: Online Resource
    ISSN: 1756-2848 , 1756-2848
    URL: Article
    DOI: 10.1177/1756284820979165
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2020
    detail.hit.zdb_id: 2440710-0
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  • 2
    Online Resource
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    Swelling behaviors and gel strength studies of wheat straw-composite superabsorbent
    SAGE Publications ; 2014
    In:  Journal of Composite Materials Vol. 48, No. 19 ( 2014-08), p. 2341-2348
    Details
    In: Journal of Composite Materials, SAGE Publications, Vol. 48, No. 19 ( 2014-08), p. 2341-2348
    Abstract: A novel wheat straw-composite superabsorbent with high gel strength and high water absorbency was prepared by graft polymerization with acrylic acid, acrylamide and maleic anhydride-modified wheat straw, using N, N-methylene-bis-acrylamide as a crosslinker and ammonium persulfate and sodium bisulfite as redox initiators. Factors influencing water absorbency and gel strength of the superabsorbent composite, such as amount of maleic anhydride-modified wheat straw, crosslinker amount and initiator amount, were investigated. Morphologies and structure of the wheat straw-composite superabsorbent were characterized by Fourier transform infrared spectroscopy, scanning electron microscope and X-ray diffraction. Composite superabsorbent with modified wheat straw as high as 25 wt% still has water absorbency of 435 g/g. Fourier transform infrared spectroscopy spectra indicate the structure of wheat straw graft copolymer. Scanning electron microscope data show that the discontinuous sheet structures of wheat straw disappear and gel aggregates with many large microporous holes and small capillary pores are formed after wheat straw graft modification. The wheat straw-composite superabsorbent has better thermal stability than those of raw wheat straw and maleic anhydride-modified wheat straw.
    Type of Medium: Online Resource
    ISSN: 0021-9983 , 1530-793X
    URL: Article
    DOI: 10.1177/0021998313498102
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2014
    detail.hit.zdb_id: 160490-9
    detail.hit.zdb_id: 2081924-9
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  • 3
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    Online Resource
    Simultaneous Bilateral vs Unilateral Carotid Artery Stenting : 30-Day and 1-Year Results
    SAGE Publications ; 2016
    In:  Journal of Endovascular Therapy Vol. 23, No. 2 ( 2016-04), p. 258-266
    Details
    In: Journal of Endovascular Therapy, SAGE Publications, Vol. 23, No. 2 ( 2016-04), p. 258-266
    Abstract: Purpose: To evaluate clinical outcomes of simultaneous bilateral carotid artery stenting (sbCAS) compared with unilateral CAS (uCAS). Methods: The database in our institution was queried to identify all patients treated with CAS from January 2005 to December 2012. In this time frame, 120 (18.8%) patients (mean age 64.9±7.7 years; 96 men) underwent sbCAS and 517 (81.2%) patients (mean age 65.7±7.7 years; 421 men) received uCAS. The primary endpoint was the composite of stroke, myocardial infarction, or death within 30 days or any ipsilateral stroke within 1 year. Results: There was no significant difference in the rates of the primary endpoint between the sbCAS and uCAS groups (6.7% vs 4.6%, p=0.358). The rates of the primary endpoint among symptomatic patients was 8.0% in the sbCAS group and 5.0% in the uCAS group (p=0.299) and 3.1% and 4.0%, respectively (p=0.821) among asymptomatic patients. During the 30-day periprocedural period, the rates of the primary endpoint did not differ significantly between the sbCAS and uCAS groups among all patients (5.8% vs 4.4%, p=0.479), symptomatic patients (6.8% vs 5.0%, p=0.594), or asymptomatic patients (3.1% vs 3.5%, p 〉 0.999). After this period, the incidences of any ipsilateral stroke were similarly low (0.8% and 0.2%, respectively; p=0.342). Conclusion: The study showed that simultaneous bilateral CAS had no more adverse events than unilateral CAS during the periprocedural period or within 1 year. This 1-stage strategy may become a valuable alternative in the treatment of patients with severe bilateral carotid stenosis.
    Type of Medium: Online Resource
    ISSN: 1526-6028 , 1545-1550
    URL: Article
    DOI: 10.1177/1526602815626900
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2016
    detail.hit.zdb_id: 2049858-5
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  • 4
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    Regeneratively cooled scramjet heat transfer calculation and comparison with experimental data
    SAGE Publications ; 2014
    In:  Proceedings of the Institution of Mechanical Engineers, Part G: Journal of Aerospace Engineering Vol. 228, No. 8 ( 2014-06), p. 1227-1234
    Details
    In: Proceedings of the Institution of Mechanical Engineers, Part G: Journal of Aerospace Engineering, SAGE Publications, Vol. 228, No. 8 ( 2014-06), p. 1227-1234
    Abstract: Regeneratively cooled scramjet heat transfer calculation method was developed using three-dimensional calculation for engine solid wall heat conduction. The scramjet thermal environment was determined by engine heat flux measurement and the engine three-dimensional combustion flow calculations. Different heat transfer relationships in the laminar, transition and turbulence fuel flow regions were applied. The cooling fuel flow distribution data inside combustion chamber side panel were obtained by three-dimensional fuel cooling flow calculation. The results of a light weight regeneratively cooled combustion chamber heat transfer tests were adopted to verify the calculation method. The comparisons showed good agreement, indicating that the calculation method is applicable.
    Type of Medium: Online Resource
    ISSN: 0954-4100 , 2041-3025
    URL: Article
    DOI: 10.1177/0954410013488737
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2014
    detail.hit.zdb_id: 2032759-6
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  • 5
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    Tribological property study of novel water-soluble triazine derivative
    SAGE Publications ; 2014
    In:  Proceedings of the Institution of Mechanical Engineers, Part J: Journal of Engineering Tribology Vol. 228, No. 4 ( 2014-04), p. 445-453
    Details
    In: Proceedings of the Institution of Mechanical Engineers, Part J: Journal of Engineering Tribology, SAGE Publications, Vol. 228, No. 4 ( 2014-04), p. 445-453
    Abstract: 2,4-Di-(diethanolamine)-6-(diethanolaminedithiocarbamate)-1,3,5-triazine, a novel water-soluble triazine derivative, was synthesized. As additive in pure water and water-glycol, its tribological behaviors were evaluated by a four-ball tester. The results showed that this new triazine derivative exhibited excellent extreme pressure, antiwear, and friction-reducing properties. The compound can be used as a new multifunctional lubricant additive in pure water and water-glycol. The wear scar diameter and friction coefficient increased along with the rotation speed under the condition of using water-glycol as base liquid. The morphology of worn surface and the element composition of the surface were analyzed by scanning electron microscopy, energy-dispersive X-ray spectroscopy, and X-ray photoelectron spectroscopy. The analysis results showed that the additive generated a boundary lubricating and a protecting film, which contained FeOx, FeSO 4 , FeS 2 , and organic N-containing compounds. This consequence may contribute to the improvement of tribological properties of water-base lubricant.
    Type of Medium: Online Resource
    ISSN: 1350-6501 , 2041-305X
    URL: Article
    DOI: 10.1177/1350650113513571
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2014
    detail.hit.zdb_id: 2032767-5
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  • 6
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    Investigation on the influence factors for the fracturing effect in fractured tight reservoirs using the numerical simulation
    SAGE Publications ; 2022
    In:  Science Progress Vol. 105, No. 1 ( 2022-01), p. 003685042110703-
    Details
    In: Science Progress, SAGE Publications, Vol. 105, No. 1 ( 2022-01), p. 003685042110703-
    Abstract: Taking the fractured tight reservoir of the Fengcheng Formation in Mahu Depression as the research object, the RFPA software, a numerical simulation platform of real fracture process, was used to study the fracture propagation laws in fractured tight reservoirs during the fracturing process. On this basis, the influences of different factors on the fracture propagation laws in the fractured tight reservoirs were investigated, the influences of various factors on fracture propagation were quantitatively analyzed by the gray correlation method, and then the fractability calculation model for evaluating the fracturing effects was obtained by the analytic hierarchy process method. The results show that when the fracture angle is less than 70°, the natural fracture controls the hydraulic fracture propagation direction, whereas when the fracture angle is greater than 70°, the maximum horizontal principal stress controls the hydraulic fracture propagation direction. With the increase of the fracture angle, the hydraulic fracturing area firstly decreases and then increases, whereas with the increase of the fracture density, the hydraulic fracturing area gradually increases. The hydraulic fracturing area increases as the fracture compressive strength, tensile strength and elastic modulus reduction factor increase, whereas the hydraulic fracturing area decreases as the fracture Poisson's ratio reduction factor increases. Based on the gray correlation method, the ranking of the fracturing effect is clarified as fracture density 〉 horizontal stress difference 〉 fracture angle 〉 elastic modulus 〉 compressive strength 〉 tensile strength 〉 Poisson's ratio. Using the analytic hierarchy process, a model for calculating the reservoir fractability index is established, and has a good positive correlation with the dimensionless fracturing area.
    Type of Medium: Online Resource
    ISSN: 0036-8504 , 2047-7163
    URL: Article
    DOI: 10.1177/00368504211070396
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2022
    detail.hit.zdb_id: 2483680-1
    detail.hit.zdb_id: 2199376-2
    SSG: 11
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  • 7
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    The therapeutic potential of quercetin for cigarette smoking–induced chronic obstructive pulmonary disease: a narrative review
    SAGE Publications ; 2023
    In:  Therapeutic Advances in Respiratory Disease Vol. 17 ( 2023-01), p. 175346662311708-
    Details
    In: Therapeutic Advances in Respiratory Disease, SAGE Publications, Vol. 17 ( 2023-01), p. 175346662311708-
    Abstract: Quercetin is a flavonoid with antioxidant and anti-inflammatory properties. Quercetin has potentially beneficial therapeutic effects for several diseases, including cigarette smoking–induced chronic obstructive pulmonary disease (CS-COPD). Many studies have shown that quercetin’s antioxidant and anti-inflammatory properties have positive therapeutic potential for CS-COPD. In addition, quercetin’s immunomodulatory, anti-cellular senescence, mitochondrial autophagy–modulating, and gut microbiota–modulating effects may also have therapeutic value for CS-COPD. However, there appears to be no review of the possible mechanisms of quercetin for treating CS-COPD. Moreover, the combination of quercetin with common therapeutic drugs for CS-COPD needs further refinement. Therefore, in this article, after introducing the definition and metabolism of quercetin, and its safety, we comprehensively presented the pathogenesis of CS-COPD related to oxidative stress, inflammation, immunity, cellular senescence, mitochondrial autophagy, and gut microbiota. We then reviewed quercetin’s anti-CS-COPD effects, performed by influencing these mechanisms. Finally, we explored the possibility of using quercetin with commonly used drugs for treating CS-COPD, providing a basis for future screening of excellent drug combinations for treating CS-COPD. This review has provided meaningful information on quercetin’s mechanisms and clinical use in treating CS-COPD.
    Type of Medium: Online Resource
    ISSN: 1753-4666 , 1753-4666
    URL: Article
    DOI: 10.1177/17534666231170800
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2023
    detail.hit.zdb_id: 2387506-9
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  • 8
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    Travel Behavior Reactions to Transit Service Disruptions : Study of Metro SafeTrack Projects in Washington, D.C.
    SAGE Publications ; 2017
    In:  Transportation Research Record: Journal of the Transportation Research Board Vol. 2649, No. 1 ( 2017-01), p. 79-88
    Details
    In: Transportation Research Record: Journal of the Transportation Research Board, SAGE Publications, Vol. 2649, No. 1 ( 2017-01), p. 79-88
    Abstract: Major transit infrastructure disruptions have become more frequent because of increasing maintenance needs for aging infrastructure, system failures, and disasters. Understanding travel behavior reactions to service disruptions on the basis of empirical observations is a fundamental step toward planning and operating an efficient and reliable transportation system. Few studies in the literature have investigated the behavioral and system impact of transit service disruptions. To bridge this gap in the literature, this research investigated travel behavioral reactions to transit service disruptions during the Metro SafeTrack projects in Washington, D.C., with the use of a unique panel survey. This study offers new insights on multimodal, multidimensional travel behavioral responses to major transit network disruptions, a critically theoretical prerequisite for developing and implementing effective strategies (e.g., how to deploy the reserve bus fleet optimally) that minimize system impact and improve transit system reliability and resilience.
    Type of Medium: Online Resource
    ISSN: 0361-1981 , 2169-4052
    URL: Article
    DOI: 10.3141/2649-09
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2017
    detail.hit.zdb_id: 2403378-9
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  • 9
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    Analyzing Simulation-Based Active Traffic Management Impact on a Large-Scale Regional Network
    SAGE Publications ; 2019
    In:  Transportation Research Record: Journal of the Transportation Research Board Vol. 2673, No. 8 ( 2019-08), p. 638-647
    Details
    In: Transportation Research Record: Journal of the Transportation Research Board, SAGE Publications, Vol. 2673, No. 8 ( 2019-08), p. 638-647
    Abstract: A vast number of real-time corridor management strategies have been introduced because the dynamics of traffic patterns and increased congestion result in challenging problems on road systems. Although these strategies can offer positive impacts on regional traffic, their evaluation tools are often limited to the scope of one specific corridor. To fill this gap, this study integrates a mesoscopic dynamic traffic assignment simulation model with an existing traffic-responsive ramp metering strategy. This integrated model is suitable for network-wide analysis and large-scale simulation of integrated corridor management strategies. The integrated modeling platform is demonstrated as a practice-ready tool. We present a case study that explores the benefits of metering control under various traffic conditions in a real-world network in Maryland. Both local and network-wide impacts are illustrated in the case study. This is one of the first attempts to simultaneously analyze network-wide traffic impacts and capture minute-by-minute demand–supply interactions under managed corridor strategies. The results indicate that ramp metering is beneficial even under non-recurrent traffic conditions at multiple spatial resolutions.
    Type of Medium: Online Resource
    ISSN: 0361-1981 , 2169-4052
    URL: Article
    DOI: 10.1177/0361198119845650
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2019
    detail.hit.zdb_id: 2403378-9
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  • 10
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    Simultaneous Identification of Characteristic Components in HPLC-PDA-ELSD Fingerprint Profile of Ginkgo biloba Leaves Extract
    SAGE Publications ; 2019
    In:  Natural Product Communications Vol. 14, No. 6 ( 2019-06), p. 1934578X1985790-
    Details
    In: Natural Product Communications, SAGE Publications, Vol. 14, No. 6 ( 2019-06), p. 1934578X1985790-
    Abstract: This is an updated fingerprint profile for the simultaneous identification of 29 compounds, mainly including characteristic -terpene trilactones and flavonoid glycosides from Ginkgo biloba leaves (EGb) by employing a high-performance liquid chromatography-photodiode array-evaporative light scattering detector method. Compounds 1 and 6 had not been previously either detected or described in any EGb samples. In general, these 29 compounds were distributed into 5 regions in the fingerprint according to their different structural properties. This efficient analytical method could be generally applied to the quality control of EGb761 and other commercially available EGb products in the Chinese active pharmaceutical ingredients market.
    Type of Medium: Online Resource
    ISSN: 1934-578X , 1555-9475
    URL: Article
    DOI: 10.1177/1934578X19857902
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2019
    detail.hit.zdb_id: 2430442-6
    SSG: 15,3
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