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  • SAGE Publications  (12)
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  • SAGE Publications  (12)
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  • 1
    Online Resource
    Online Resource
    SAGE Publications ; 2020
    In:  International Journal of Advanced Robotic Systems Vol. 17, No. 3 ( 2020-05-01), p. 172988142091376-
    In: International Journal of Advanced Robotic Systems, SAGE Publications, Vol. 17, No. 3 ( 2020-05-01), p. 172988142091376-
    Abstract: This article focuses on the problem of optimal linear quadratic Gaussian control for networked control systems with multiple delays and packet dropouts. The main contributions are twofold. Firstly, based on the introduced maximum principle for linear quadratic Gaussian system with multiple input delays and packet dropouts, a nonhomogeneous relationship between the state and costate is obtained, which is the key technical tool to solve the problem. Secondly, a necessary and sufficient condition for the optimal networked control problem is given in virtue of the coupled Riccati equations, and the explicit expression of the optimal controller is presented. Numerical examples are shown to illustrate the proposed algorithm.
    Type of Medium: Online Resource
    ISSN: 1729-8814 , 1729-8814
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2020
    detail.hit.zdb_id: 2202393-8
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  • 2
    Online Resource
    Online Resource
    SAGE Publications ; 2020
    In:  Proceedings of the Institution of Mechanical Engineers, Part J: Journal of Engineering Tribology Vol. 234, No. 9 ( 2020-09), p. 1425-1435
    In: Proceedings of the Institution of Mechanical Engineers, Part J: Journal of Engineering Tribology, SAGE Publications, Vol. 234, No. 9 ( 2020-09), p. 1425-1435
    Abstract: To investigate the response of material to cavitation erosion, a comparative work was carried out on three materials, aluminum, copper alloy and titanium. Ultrasonic cavitation erosion was produced as the specimen was submerged in the deionized water. Within a cavitation erosion period of 120 min, the cumulative mass loss was measured at certain time intervals. Surface structure and cavitation damage patterns were observed for the three materials. Microhardness was measured and compared. The results indicate that the cumulative mass loss of aluminum is the highest among the three materials, while the slightest material removal is associated with titanium, which is still in the initial stage of cavitation erosion after 120 min of cavitation erosion. The surface of the aluminum specimen is eroded rapidly after the cavitation erosion commences. Large erosion pits dominate the eroded surface as the cavitation erosion progresses. The surface of the titanium specimen manifests needle-like erosion pits and cleavage cracks. Even at the later stage of the cavitation erosion, non-eroded surface elements are identifiable. The cavitation erosion pattern on the copper alloy specimen surface is related to the twin-phase crystal structure and large erosion pits are produced at the later stage of cavitation erosion. The highest resistance to the cavitation erosion of titanium is related to the close-packed hexagonal structure and the weak slip effect associated.
    Type of Medium: Online Resource
    ISSN: 1350-6501 , 2041-305X
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2020
    detail.hit.zdb_id: 2032767-5
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  • 3
    In: Experimental Biology and Medicine, SAGE Publications
    Abstract: Increasing evidence indicates that deep venous thrombosis (DVT) is a common peripheral vascular disease. This study aims to investigate the mechanisms of thioredoxin-interacting protein (TXNIP) and nod-like receptor protein 3 (NLRP3) inflammasome in deep venous thrombosis (DVT). A total of 66 Sprague–Dawley (SD) rats were employed to conduct DVT model. DVT rat was treated with silenced TXNIP (si-TXNIP) lentivirus and MCC950 (a NLRP3 inhibitor). The thrombosis weight and weight/length ratio, tissue factor, inflammatory factors, superoxide dismutase (SOD), malondialdehyde (MDA), and glutathione peroxidase (GSH-Px) were measured. Hematoxylin–eosin (H & E) staining was used to investigate the pathological change. Western blotting was used to determine the protein expression level. The expression level of thioredoxin (TRx) was suppressed, whereas TXNIP and NLRP3 were elevated in DVT rat. Si-TXNIP or MCC950 could reduce the thrombosis weight and weight/length ratio, ameliorate the pathological change, and decrease inflammatory reaction. Mechanistically, si-TXNIP or MCC950 inhibited the expression levels of TXNIP, NLRP3, and interleukin (IL)-1β while elevating the TRx level, thereby suppressing the DVT. Our study indicated that si-TXNIP or MCC950 injection rescued the injury of vein induced by DVT. The possible mechanisms connected with the inhibition of TXNIP and NLRP3. TXNIP is a possible therapeutic target for DVT.
    Type of Medium: Online Resource
    ISSN: 1535-3702 , 1535-3699
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2023
    detail.hit.zdb_id: 2020856-X
    SSG: 12
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  • 4
    In: Experimental Biology and Medicine, SAGE Publications, Vol. 234, No. 7 ( 2009-07), p. 785-793
    Abstract: Kai Xin San (KXS), a traditional Chinese herbal medicine, has been used clinically for the treatment of depressive disorders and cognitive impairment for centuries. However, the effects of KXS on cognitive dysfunction induced by depression have not been evaluated scientifically. The present study aimed to explore the antidepressant-like and nootropic effects of an aqueous extract of KXS (at doses of 0.3, 0.9, and 2.7 g/kg/day) using chronic mild stress (CMS) as a model of depression. Depressive symptoms were analyzed using the sucrose-preference and novelty-induced inhibition of feeding tests. Cognitive function was evaluated using a two-way active avoidance task. Serum corticosterone and adrenocorticotropic hormone (ACTH) levels, acetylcholinesterase (AChE) protein expression in the hippocampus, and monoamine neurotransmitter concentrations in the prefrontal cortex and hippocampus were also determined to elucidate the neurochemical mechanisms. Experimental results showed that KXS aqueous extract significantly ameliorated the CMS-induced depressive symptoms, including the reduced preference index and prolonged latency to novelty-suppressed feeding. Simultaneously, KXS significantly reversed the CMS-induced decrease in the numbers of active avoidance and active movement distances and increase in the numbers of the passive avoidance and passive movement distances, thereby producing nootropic effects in the two-way active avoidance test. KXS also inhibited the increased AChE expression in the hippocampus, up-regulated the decreased monoamine neurotransmitter concentrations of both brain areas and reduced the elevated ACTH concentrations in the serum induced by CMS. Taken together, these results indicate that KXS exerts its antidepressant-like and nootropic effects in the CMS model by modulating the HPA axis, monoamine neurotransmitter and cholinergic systems.
    Type of Medium: Online Resource
    ISSN: 1535-3702 , 1535-3699
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2009
    detail.hit.zdb_id: 2020856-X
    SSG: 12
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  • 5
    Online Resource
    Online Resource
    SAGE Publications ; 2019
    In:  International Journal of Advanced Robotic Systems Vol. 16, No. 3 ( 2019-05-01), p. 172988141985161-
    In: International Journal of Advanced Robotic Systems, SAGE Publications, Vol. 16, No. 3 ( 2019-05-01), p. 172988141985161-
    Abstract: The singular systems, which could widely describe more general systems and present traits of physical features, are discussed in this study. Taking the fact that noises always exist in the state and output measurement of one singular system into consideration, which may cause some errors and decrease system performance, this article devotes itself to the dissipative control for discrete-time singular Markov jump systems (SMJSs) with multiplicative noises. To deal with the asynchronous phenomena between the system modes and the controller modes, a set of Markov chains are constructed. To make sure the closed-loop singular system is dissipative, a set of sufficient conditions are derived based on the linear matrix inequalities, and then the asynchronous controller is designed to ensure that SMJSs are stochastically admissible and strictly dissipative. Finally, a simulation example is carried out to verify the correctness of the derived theorem. The designed asynchronous controller improves the robustness of the controller and overcomes the asynchronous phenomenon. This control method can be applied in the fields of robot control system.
    Type of Medium: Online Resource
    ISSN: 1729-8814 , 1729-8814
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2019
    detail.hit.zdb_id: 2202393-8
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  • 6
    Online Resource
    Online Resource
    SAGE Publications ; 2020
    In:  International Journal of Advanced Robotic Systems Vol. 17, No. 1 ( 2020-01-01), p. 172988141989666-
    In: International Journal of Advanced Robotic Systems, SAGE Publications, Vol. 17, No. 1 ( 2020-01-01), p. 172988141989666-
    Abstract: Recently, most of the existing mobile robot indoor positioning systems (IPSs) use infrared sensors, cameras, and other extra infrastructures. They usually suffer from high cost and special hardware implementation. In order to address the above problems, this article proposes a Wi-Fi-based indoor mobile robot positioning system and designs and develops a robot positioning platform based on the commercial Wi-Fi devices, such as Wi-Fi routers. Furthermore, a robust principal component analysis-based extreme learning machine algorithm is proposed to address the issue of noisy measurements in IPSs. Real-world robot indoor positioning experiments are extensively carried out and the results verify the effectiveness and superiority of the proposed system.
    Type of Medium: Online Resource
    ISSN: 1729-8814 , 1729-8814
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2020
    detail.hit.zdb_id: 2202393-8
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  • 7
    In: SAGE Open, SAGE Publications, Vol. 12, No. 3 ( 2022-07), p. 215824402211201-
    Abstract: Work-related use of information and communication technologies after hours (W_ICTs) has significant impacts on both organizations and individuals. However, limited research has explored the detrimental effects of W_ICTs behavior on work-family conflict. To fill this gap, based upon the job demands-resources (JD-R) model and daily diary design with a multilevel model method, we collected 76 employees who completed a 5-day investigation, resulting in 380 observations. Our study found that engaging in W_ICTs behavior positively influenced employees’ own work role overload, which led to an increase in work-family conflict. Furthermore, we found that the positive relationship between work role overload and work-family conflict is stronger when employees’ job autonomy is at lower levels. Our findings provide strong support for the proposed moderated mediation model and extend our understanding of W_ICTs behaviors consequences.
    Type of Medium: Online Resource
    ISSN: 2158-2440 , 2158-2440
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2022
    detail.hit.zdb_id: 2628279-3
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  • 8
    Online Resource
    Online Resource
    SAGE Publications ; 2023
    In:  Proceedings of the Institution of Mechanical Engineers, Part D: Journal of Automobile Engineering
    In: Proceedings of the Institution of Mechanical Engineers, Part D: Journal of Automobile Engineering, SAGE Publications
    Abstract: Speed guidance is a significant application in driver assistance system or driverless automated system. Considering the traditional Pearl model-based trajectory planning, this paper proposes an improved method based on window constraints to enhance the rationality at intersection positions. To solve the problem, where the slopes of traditional time-distance Pearl curve at the two boundaries generate relatively low values and which is not in accordance with the actual situation, a new window constraint is used to guide the vehicle passing through the intersection at a high speed. Regarding the new window constraints, together with the maximum speed, tolerating accelerated speed constraints, and traffic signal length constraints, a multi-variable and single objective optimization improved nonlinear programing scheme is applied to obtain the most comfort trajectory of passengers for speed guidance. Simulation results show that, the proposed method presents better performance in traveling time and trajectory smoothness compared with the traditional method under different initial vehicle speeds at upstream intersections and signal offset cases.
    Type of Medium: Online Resource
    ISSN: 0954-4070 , 2041-2991
    RVK:
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2023
    detail.hit.zdb_id: 2032754-7
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  • 9
    Online Resource
    Online Resource
    SAGE Publications ; 2018
    In:  Advances in Mechanical Engineering Vol. 10, No. 1 ( 2018-01), p. 168781401774770-
    In: Advances in Mechanical Engineering, SAGE Publications, Vol. 10, No. 1 ( 2018-01), p. 168781401774770-
    Abstract: This article is concerned with the problem of resilient asynchronous H ∞ static output feedback control for discrete-time Markov jump linear systems. By Finsler’s Lemma, and with the help of two sets of slack variables, the product terms of system matrices and Lyapunov matrices are decoupled. Resilient asynchronous controller is designed to improve the robustness of the controller and overcome the drawback that the controller cannot get the information of the system’s mode. The controller that makes sure the closed-loop system is stochastically stable and with prescribed H ∞ performance is designed. The bilinear matrix inequalities are given as the sufficient conditions for the controller design, which can be solved using linear matrix inequalities along with line search. This control strategy can be used in many practical application fields, such as robot control, aircraft, and traffic control.
    Type of Medium: Online Resource
    ISSN: 1687-8140 , 1687-8140
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2018
    detail.hit.zdb_id: 2501620-9
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  • 10
    In: ASN Neuro, SAGE Publications, Vol. 6, No. 6 ( 2014-10-01), p. 175909141455841-
    Abstract: Edaravone is clinically used for treatment of patients with acute cerebral infarction. However, the effect of double application of edaravone on neurogenesis in the hippocampus following ischemia remains unknown. In the present study, we explored whether pre- and posttreatment of edaravone had any effect on neural stem/progenitor cells (NSPCs) in the subgranular zone of hippocampus in a rat model of transient global cerebral ischemia and elucidated the potential mechanism of its effects. Male Sprague-Dawley rats were divided into three groups: sham-operated ( n = 15), control ( n = 15), and edaravone-treated ( n = 15) groups. Newly generated cells were labeled by 5-bromo-2-deoxyuridine. Immunohistochemistry was used to detect neurogenesis. Terminal deoxynucleotidyl transferase-mediated dUTP-biotin nick-end labeling was used to detect cell apoptosis. Reactive oxygen species (ROS) were detected by 2,7-dichlorofluorescien diacetate assay in NSPCs in vitro. Hypoxia-inducible factor-1α (HIF-1α) and cleaved caspase-3 proteins were quantified by western blot analysis. Treatment with edaravone significantly increased the number of NSPCs and newly generated neurons in the subgranular zone ( p  〈  .05). Treatment with edaravone also decreased apoptosis of NSPCs ( p  〈  .01). Furthermore, treatment with edaravone significantly decreased ROS generation and inhibited HIF-1α and cleaved caspase-3 protein expressions. These findings indicate that pre- and posttreatment with edaravone enhances neurogenesis by protecting NSPCs from apoptosis in the hippocampus, which is probably mediated by decreasing ROS generation and inhibiting protein expressions of HIF-1α and cleaved caspase-3 after cerebral ischemia.
    Type of Medium: Online Resource
    ISSN: 1759-0914 , 1759-0914
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2014
    detail.hit.zdb_id: 2485467-0
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