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  • 1
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    Online Resource
    The Psychological Well-Being of Taiwanese Youth : School versus Family Context from Early to Late Adolescence
    SAGE Publications ; 2009
    In:  International Sociology Vol. 24, No. 3 ( 2009-05), p. 397-429
    Details
    In: International Sociology, SAGE Publications, Vol. 24, No. 3 ( 2009-05), p. 397-429
    Abstract: This study examines the growth trajectory of the psychological well-being of Taiwanese adolescents from early to late adolescence. Under the competitive educational system in Taiwan, family and school context are two major loci accounting for the developmental outcome. Data are taken from the Taiwan Youth Project, which is a longitudinal panel study of 2696 students since the year 2000. The study uses individual depressive symptoms as the dependent variable. Family cohesion, family educational strategy as well as classroom effects at school are chosen to indicate the potential contextual influence. Using the latent growth curve method, the analysis confirms that family and school factors do produce different effects over time. Family context is salient at the initial status, but not for subsequent development. Class cohesion as well as adolescents' perceptions of unfairness by teachers determine the depressive level, the linear slope and the non-linear quadratic growth curve. In other words, once the adolescent gets used to junior high school, the school context tends to exert more pronounced effects. Further analysis on gender comparisons indicates that selective family and school effects are more pronounced among females, with a greater degree of depressive symptoms over time. The article concludes that while family and school have different impacts on the growth curve of individual depressive symptoms, the school context exerts salient effects over an adolescent's life course.
    Type of Medium: Online Resource
    ISSN: 0268-5809 , 1461-7242
    URL: Article
    DOI: 10.1177/0268580909102914
    RVK:
    MN 1000
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2009
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  • 2
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    Artistic robotic pencil sketching using closed-loop force control
    SAGE Publications ; 2022
    In:  Proceedings of the Institution of Mechanical Engineers, Part C: Journal of Mechanical Engineering Science Vol. 236, No. 17 ( 2022-09), p. 9753-9762
    Details
    In: Proceedings of the Institution of Mechanical Engineers, Part C: Journal of Mechanical Engineering Science, SAGE Publications, Vol. 236, No. 17 ( 2022-09), p. 9753-9762
    Abstract: This study introduces an artistic robotic painting system. The main purpose was to use a force sensor combined with a 6-axis robotic arm to create pencil sketches. Compared with other painting robots, our system has additional tactile sensing that can overcome the problem of pencil wear and can simulate the feeling of human sketches. To provide the robot with the capability to create paintings, our experiment used neural style transfer technology to extract the content and style image features and recomposed them into a new artwork. The newly generated image was processed for edge detection and further layered using methods, such as k-means clustering and image grayscale quantisation, resulting in a contour layer and multiple background layers. We carried out path planning of different layers according to the layering result, and we sorted the pixels by finding the shortest distance between them to plan a feasible path for the robotic arm at a higher speed. Finally, in the robotic arm painting experiment, we conducted two types of art creation: Chinese brush painting and pencil sketching. In the first type, we used position control to create a Chinese brush painting, and in the second type, we used a proportional-integral-derivative (PID) controller for force control to create pencil sketching. The experimental results show the validity of the proposed techniques in artistic robotic painting, both in Chinese brush painting and pencil sketching, with painting times of less than 30 min.
    Type of Medium: Online Resource
    ISSN: 0954-4062 , 2041-2983
    URL: Article
    DOI: 10.1177/09544062221096946
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2022
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  • 3
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    Intermittent theta burst stimulation over the posterior superior temporal sulcus for children with autism spectrum disorder: A 4-week randomized blinded controlled trial followed by another 4-week open-label intervention
    SAGE Publications ; 2021
    In:  Autism Vol. 25, No. 5 ( 2021-07), p. 1279-1294
    Details
    In: Autism, SAGE Publications, Vol. 25, No. 5 ( 2021-07), p. 1279-1294
    Abstract: The posterior superior temporal sulcus is a potential therapeutic target of brain stimulation for autism spectrum disorder. We conducted a 4-week randomized, single-blind parallel sham-controlled trial, followed by additional 4-week open-label intervention to evaluate the feasibility and efficacy regarding intermittent theta burst stimulation over the bilateral posterior superior temporal sulcus in autism spectrum disorder. In total, 78 intellectually able children and adolescents were randomized to the active ( n = 40) and sham groups ( n = 38). During the first 4 weeks, the active group received two-session/week intermittent theta burst stimulation, whereas the sham group received the same number of sham stimulation. After unblinding, both groups received eight-session real stimulation over the additional 4 weeks. In total, 91% participants completed the protocol with mild and transitory side-effects. There was no significant group-by-time interaction for active versus sham group on clinical symptoms and social cognitive performances in the first 4 weeks. The within-group analysis revealed 8 weeks (including a 4-week blind trial and a 4-week open-label intervention) of intermittent theta burst stimulation achieved greater efficacy than 4-week interventions. Participants with higher intelligence, better social cognitive performances, alongside less attention-deficit hyperactivity disorder severity at baseline, were more likely to be responders. Our study demonstrated the feasibility of long-term intermittent theta burst stimulation over the posterior superior temporal sulcus in children and adolescents with autism spectrum disorder. However, the findings from the first 4-week blind trial do not support the therapeutic efficacy of intermittent theta burst stimulation over the posterior superior temporal sulcus on the clinical symptoms and cognitive performance of social impairment, given the current stimulation protocol. The exploratory analyses suggest that the therapeutic efficacy might be moderated by several individual characteristics and more intermittent theta burst stimulation sessions. Lay abstract Intermittent theta burst stimulation is a varied form of repetitive transcranial magnetic non-invasive brain stimulation technique used to treat several neurological and psychiatric disorders. Its feasibility and therapeutic effects on the bilateral posterior superior temporal sulcus in children with autism are unknown. We conducted a single-blind, sham-controlled parallel randomized clinical trial in a hitherto largest sample of intellectually able children with autism ( N = 78). Participants randomized to the active group received two-session/week intermittent theta burst stimulation for continuous 8 weeks. Those in the sham group received two-session/week sham stimulations in the first 4 weeks and then active intervention for the following 4 weeks after unblinding. First, we found that continuous 8-week intermittent theta burst stimulation on the bilateral posterior superior temporal sulcus in children with autism is safe and tolerable. Second, we found that 8-week intermittent theta burst stimulation produced greater therapeutic efficacy, although we did not find any significant effects of 4-week intermittent theta burst stimulation on core symptoms and social cognitive performances in autism. Further analysis revealed that participants with higher intelligence and better social cognitive performance, alongside less attention-deficit hyperactivity disorder severity at baseline, were more likely to be responders. This study identified that the factors contribute to responders and the results suggest that longer courses of non-invasive brain stimulation may be needed to produce therapeutic benefits in autism, with consideration of heterogeneous responses.
    Type of Medium: Online Resource
    ISSN: 1362-3613 , 1461-7005
    URL: Article
    DOI: 10.1177/1362361321990534
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2021
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  • 4
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    The Relation among Aldosterone, Galectin-3, and Myocardial Fibrosis: A Prospective Clinical Pilot Follow-Up Study
    SAGE Publications ; 2016
    In:  Journal of Investigative Medicine Vol. 64, No. 6 ( 2016-08), p. 1109-1113
    Details
    In: Journal of Investigative Medicine, SAGE Publications, Vol. 64, No. 6 ( 2016-08), p. 1109-1113
    Abstract: Primary aldosteronism has been associated with myocardial fibrosis, and is the most common cause of secondary hypertension. We previously showed that aldosterone can induce the secretion of galectin-3. The aim of this study was to investigate the association between myocardial fibrosis and plasma galectin-3 level in patients with primary aldosteronism. We prospectively analyzed 11 patients with aldosterone-producing adenoma (APA) who received adrenalectomy from December 2006 to October 2008, and 17 patients with essential hypertension as controls. Levels of plasma galectin-3 were determined in both groups, and both groups underwent echocardiography with cyclic variations of integrated backscatter (CVIBS) to characterize tissue initially and 1 year after surgery in the APA group. Diastolic blood pressure, concentration of plasma aldosterone and aldosterone-renin ratio were significantly higher, and serum potassium level and plasma renin activity significantly lower in the APA group compared to the controls. In addition, left ventricular mass index was significantly higher and CVIBS significantly lower in the APA group (7.3±2.0 vs 9.2±1.7 dB, p=0.015). Furthermore, the concentration of plasma galectin-3 was significantly higher in the APA group (2.1±0.9 vs 1.1±0.6 ng/mL, p=0.005) compared to the controls. CVIBS was correlated to plasma galectin-3 level. In the APA group, CVIBS increased significantly (7.3±2.0 to 9.2±2.4 dB, p=0.032) and plasma galectin-3 decreased (2.1±0.9 to 1.2±0.6, p=0.049) 1 year postadrenalectomy. The patients with APA had increased myocardial fibrosis, and this was associated with a higher plasma galectin-3 level. Both increased myocardial fibrosis and plasma galectin-3 level recovered at least partially after adrenalectomy. Trial registration number 200611031R; Results.
    Type of Medium: Online Resource
    ISSN: 1081-5589 , 1708-8267
    URL: Article
    DOI: 10.1136/jim-2015-000014
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2016
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  • 5
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    The Chinese Version of the Subjective Happiness Scale: Validation and Convergence With Multidimensional Measures
    SAGE Publications ; 2020
    In:  Journal of Psychoeducational Assessment Vol. 38, No. 2 ( 2020-04), p. 222-235
    Details
    In: Journal of Psychoeducational Assessment, SAGE Publications, Vol. 38, No. 2 ( 2020-04), p. 222-235
    Abstract: This article aimed to establish the psychometric properties of the Chinese version of the Subjective Happiness Scale (SHS-C) and to investigate the convergence between SHS-C and multidimensional subjective well-being (MSWB). A total of 543 college students completed the following measures: the SHS-C, the MSWB scale, Rosenberg’s self-esteem scale, and the interpersonal harmony scale. The SHS-C showed adequate internal consistent reliability and test–retest reliability. Confirmatory factor analysis (CFA) showed a one-factor structure of the SHS-C, and multigroup CFA showed factor invariance between gender groups. Subjective happiness, as measured by the SHS-C, and MSWB, as measured by life satisfaction, positive affect, and negative affect, were highly correlated (above .90), suggesting convergent validity. The SHS-C was also correlated with two theoretically different but related constructs, self-esteem and interpersonal harmony, providing evidence of criterion-related validity. The results provide preliminary evidence that the SHS-C is valid with a Chinese-speaking population and that the SHS-C and MSWB may be interchangeable.
    Type of Medium: Online Resource
    ISSN: 0734-2829 , 1557-5144
    URL: Article
    DOI: 10.1177/0734282919837403
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2020
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  • 6
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    Comparison of the effect of clarithromycin triple therapy with or without N -acetylcysteine in the eradication of Helicobacter pylori : a randomized controlled trial
    SAGE Publications ; 2020
    In:  Therapeutic Advances in Gastroenterology Vol. 13 ( 2020-01), p. 175628482092730-
    Details
    In: Therapeutic Advances in Gastroenterology, SAGE Publications, Vol. 13 ( 2020-01), p. 175628482092730-
    Abstract: Whether adjunctive N-acetylcysteine (NAC) may improve the efficacy of triple therapy in the first-line treatment of Helicobacter pylori infection remains unknown. Our aim was to compare the efficacy of 14-day triple therapy with or without NAC for the first-line treatment of H. pylori. Material and methods: Between 1 January 2014 and 30 June 2018, 680 patients with H. pylori infection naïve to treatment were enrolled in this multicenter, open-label, randomized trial. Patients were randomly assigned to receive triple therapy with NAC [NAC-T14, dexlansoprazole 60 mg four times daily (q.d.); amoxicillin 1 g twice daily (b.i.d.), clarithromycin 500 mg b.i.d., NAC 600 mg b.i.d.] for 14 days, or triple therapy alone (T14, dexlansoprazole 60 mg q.d.; amoxicillin 1 g b.i.d., clarithromycin 500 mg b.i.d.) for 14 days. Our primary outcome was the eradication rates by intention to treat (ITT). Antibiotic resistance and CYP2C19 gene polymorphism were determined. Results: The ITT analysis demonstrated H. pylori eradication rates in NAC-T14 and T14 were 81.7% [276/338, 95% confidence interval (CI): 77.5–85.8%] and 84.3% (285/338, 95% CI 80.4–88.2%), respectively. In 646 participants who adhered to their assigned therapy, the eradication rates were 85.7% and 88.0% with NAC-T14 and T14 therapies, respectively. There were no differences in compliance or adverse effects. The eradication rates in subjects with clarithromycin-resistant, amoxicillin-resistant, or either clarithromycin/amoxicillin resistant strains were 45.2%, 57.9%, and 52.2%, respectively, for NAC-T14, and were 66.7%, 76.9%, and 70.0%, respectively, for T14. The efficacy of NAC-T14 and T14 was not affected by CYP2C19 polymorphism. Conclusion: Add-on NAC to triple therapy was not superior to triple therapy alone for first-line H. pylori eradication [ClinicalTrials.gov identifier: NCT02249546].
    Type of Medium: Online Resource
    ISSN: 1756-2848 , 1756-2848
    URL: Article
    DOI: 10.1177/1756284820927306
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2020
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  • 7
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    Diabetes mellitus is associated with more adverse non-hemodynamic left ventricular remodeling and less recovery in patients with primary aldosteronism
    SAGE Publications ; 2023
    In:  Journal of Investigative Medicine Vol. 71, No. 2 ( 2023-02), p. 101-112
    Details
    In: Journal of Investigative Medicine, SAGE Publications, Vol. 71, No. 2 ( 2023-02), p. 101-112
    Abstract: The elevated aldosterone in primary aldosteronism (PA) is associated with increased insulin resistance and prevalence of diabetes mellitus (DM). Both aldosterone excess and DM lead to left ventricular (LV) pathological remodeling. In this study, we investigated the impact of DM on LV non-hemodynamic remodeling in patients with PA. We enrolled 665 PA patients, of whom 112 had DM and 553 did not. Clinical, biochemical, and echocardiographic data were analyzed at baseline and 1 year after adrenalectomy. LV non-hemodynamic remodeling was represented by inappropriate excess left ventricular mass index (ieLVMI), which was defined as the difference between left ventricular mass index (LVMI) and predicted left ventricular mass index (pLVMI). Propensity score matching (PSM) was used with age, sex, systolic, and diastolic blood pressure to adjust for baseline variables. After PSM, the patient characteristics were balanced between the DM and non-DM groups, except for fasting glucose, HbA1c, and lipid profile. A total of 111 DM and 419 non-DM patients were selected for further analysis. Compared to the non-DM group, the DM group had significantly higher ieLVMI and LVMI. After multivariable linear regression analysis, the presence of DM remained a significant predictor of increased ieLVMI. After adrenalectomy, ieLVMI decreased significantly in the non-DM group but not in DM group. The presence of DM in PA patients was associated with more prominent non-hemodynamic LV remodeling and less recovery after adrenalectomy.
    Type of Medium: Online Resource
    ISSN: 1081-5589 , 1708-8267
    URL: Article
    DOI: 10.1177/10815589221141840
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2023
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  • 8
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    Mineralocorticoid receptor antagonist treatment improved arterial stiffness in patients with primary aldosteronism: a cohort study compared with adrenalectomy
    SAGE Publications ; 2023
    In:  Therapeutic Advances in Chronic Disease Vol. 14 ( 2023-01), p. 204062232211432-
    Details
    In: Therapeutic Advances in Chronic Disease, SAGE Publications, Vol. 14 ( 2023-01), p. 204062232211432-
    Abstract: Elevated arterial stiffness in patients with primary aldosteronism (PA) can be reversed after adrenalectomy; however, the effect of medical treatment with mineralocorticoid receptor antagonist (MRAs) is unknown. Objectives: The aim of this study was to evaluate the effect of MRAs and compare both treatment strategies on arterial stiffness in PA patients. Design: Prospective cohort study. Methods: We prospectively enrolled PA patients from 2006 to 2019 who received either adrenalectomy or MRA treatment (spironolactone). We compared their baseline and 1-year post-treatment biochemistry characteristics and arterial pulse wave velocity (PWV) to verify the effects of treatment and related determinant factors. Results: A total 459 PA patients were enrolled. After 1:1 propensity score matching for age, sex and blood pressure (BP), each group had 176 patients. The major determinant factors of baseline PWV were age and baseline BP. The adrenalectomy group had greater improvements in BP, serum potassium level, plasma aldosterone concentration, and aldosterone-to-renin ratio. The MRA group had a significant improvement in PWV after 1 year of treatment (1706.2 ± 340.05 to 1613.6 ± 349.51 cm/s, p  〈  0.001). There were no significant differences in post-treatment PWV ( p = 0.173) and improvement in PWV ( p = 0.579) between the adrenalectomy and MRA groups. The determinant factors for an improvement in PWV after treatment were hypertension duration, baseline PWV, and the decrease in BP. Conclusion: The PA patients who received medical treatment with MRAs had a significant improvement in arterial stiffness. There was no significant difference in the improvement in arterial stiffness between the two treatment strategies.
    Type of Medium: Online Resource
    ISSN: 2040-6223 , 2040-6231
    URL: Article
    DOI: 10.1177/20406223221143233
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2023
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  • 9
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    Autonomy and Structure Can Enhance Motivation of Volunteers in Sport Organizations
    SAGE Publications ; 2013
    In:  Perceptual and Motor Skills Vol. 117, No. 3 ( 2013-12), p. 709-719
    Details
    In: Perceptual and Motor Skills, SAGE Publications, Vol. 117, No. 3 ( 2013-12), p. 709-719
    Abstract: The goal was better understanding of the motivational factors of volunteers in non-profit sport organizations. The roles of two factors provided by supervisors to their subordinates were examined: autonomy support, i.e., the encouragement of self-initiation and emphasis on choice rather than control, and structure, i.e., the introduction of order, definite procedures, and rules. 489 sport volunteers (289 men, 200 women; M age = 31.2 yr., SD = 7.4) were administered questionnaires assessing their perceived autonomy support, structure, and motivation. Regression analysis indicated that perceived autonomy support predicted motivation. Structure also mediated the effect of perceived autonomy support on motivation. Supervisors of sport organizations should provide adequate structure for their volunteers.
    Type of Medium: Online Resource
    ISSN: 0031-5125 , 1558-688X
    URL: Article
    DOI: 10.2466/30.PMS.117x30z5
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2013
    detail.hit.zdb_id: 2066876-4
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  • 10
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    The Relationship between Psychological Factors, Inflammation, and Nutrition in Patients with Chronic Renal Failure Undergoing Hemodialysis
    SAGE Publications ; 2012
    In:  The International Journal of Psychiatry in Medicine Vol. 44, No. 2 ( 2012-08), p. 105-118
    Details
    In: The International Journal of Psychiatry in Medicine, SAGE Publications, Vol. 44, No. 2 ( 2012-08), p. 105-118
    Abstract: Hemodialysis has an adverse impact on the immunological, nutritional, and emotional status of patients. The biochemical markers of inflammation and nutrition were studied as well as the relationship of these factors to emotional symptoms. Method: One hundred and ninety-five patients undergoing hemodialysis were enrolled. The mean age was 58.5 years. Emotional symptoms were assessed using the Mini International Neuropsychiatric Interview, Hospital Anxiety and Depression Scale, Chalder Fatigue Scale, and Short-form Health-related Quality of Life. Venus blood was collected for laboratory assessment of serum hemoglobin, albumin, ferritin, C-reactive protein, interleukin (IL) 1β), IL-6, and tumor necrosis factor a. Results: Among the 195 subjects (92 men and 103 women), 47 (24.1%) fulfilled the criteria for a major depressive disorder (MDD). The IL-6 level in patients with a MDD was significantly higher than in the patients without a MDD. Significant correlation was observed among the following factors: IL-6, fatigue, and quality of life for both physical and mental components. The albumin levels showed a significant correlation with the IL-6 and depression scores. Conclusions: These results show that the serum levels of albumin and IL-6 might be laboratory markers associated with the expression of emotional symptoms in patients undergoing hemodialysis. Prospective studies are needed to determine the causal relationships among these variables.
    Type of Medium: Online Resource
    ISSN: 0091-2174 , 1541-3527
    URL: Article
    DOI: 10.2190/PM.44.2.b
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2012
    detail.hit.zdb_id: 2071478-6
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