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  • SAGE Publications  (4)
  • 1
    Online Resource
    Online Resource
    Performance Measurement System for Assessing Transportation Sustainability and Community Livability
    SAGE Publications ; 2015
    In:  Transportation Research Record: Journal of the Transportation Research Board Vol. 2531, No. 1 ( 2015-01), p. 113-120
    Details
    In: Transportation Research Record: Journal of the Transportation Research Board, SAGE Publications, Vol. 2531, No. 1 ( 2015-01), p. 113-120
    Abstract: Sustainability and livability as concepts that indicate the capability of transportation systems to maintain social well-being have been widely accepted as critical principles to improve the quality of life and health in communities. This study introduced a geographic information system as the basis for a performance measurement system to assess the two goals from the standpoint of transportation systems. The city of Buffalo, New York, was used as the case study. Various data were collected, and 20 sustainability and livability related performance measures (PMs), including transportation attributes, land use measures, living condition indicators, and systemwide indexes, were developed. Analysis of the PMs raised several policy implications and led to some suggestions. Lessons and challenges from the PM development process are summarized to help other relevant initiatives. The PMs, the supporting database, the case study, and the findings produced by the research are expected to help a wide range of stakeholders, including policy makers, planners, and transportation engineers, to gain more insights into transportation-oriented sustainability and livability performance measurement.
    Type of Medium: Online Resource
    ISSN: 0361-1981 , 2169-4052
    URL: Article
    DOI: 10.3141/2531-13
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2015
    detail.hit.zdb_id: 2403378-9
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    Online Resource
  • 2
    Online Resource
    Online Resource
    Optofluidic Platform for Rapid On-Chip Analysis of Total Phosphorus in Surface Water Using Absorption Spectrometry
    SAGE Publications ; 2022
    In:  Applied Spectroscopy Vol. 76, No. 5 ( 2022-05), p. 599-608
    Details
    In: Applied Spectroscopy, SAGE Publications, Vol. 76, No. 5 ( 2022-05), p. 599-608
    Abstract: Optofluidic devices are of high interest for online monitoring and analyzing biochemical targets in water by integrating the complex on-chip pretreatment of target analytes and spectral analysis. Compared with the traditional bulk equipment, versatile optical detection and biochemical analysis are more easily integrated on an optofluidic chip, which promotes the development of on-chip real-time rapid detection and monitoring. Here, we report an optofluidic platform for online monitoring total phosphorous in water by absorption spectrometry, which naturally combines the merits of both the photo-Fenton effect and microfluidics to realize the rapid on-chip digestion of phosphate at room temperature and normal pressure. The functional cells for chromogenic reaction and optical absorption detection are, respectively, fabricated on the platform to analyze the content of total phosphorus in surface water. In the experiment, the on-chip digestion time of phosphate is dramatically declined to 8.6 sec, and thus, the detection time is greatly shortened to a few minutes. The detection range of total phosphorus is demonstrated as 0.005–1.00 mg L −1 , which satisfies the detection requirements of most environmental water samples. Its availability for measuring the total phosphorous in real water samples is also verified. Predictably, this platform is adapted to on-chip analysis of many other biochemical targets in water.
    Type of Medium: Online Resource
    ISSN: 0003-7028 , 1943-3530
    URL: Article
    DOI: 10.1177/00037028211069148
    RVK:
    VA 2367
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2022
    detail.hit.zdb_id: 1474251-2
    SSG: 11
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    Online Resource
  • 3
    Online Resource
    Online Resource
    Behavioral Analysis of Decisions in Choice of Commercial Vehicular Mode in Urban Areas
    SAGE Publications ; 2012
    In:  Transportation Research Record: Journal of the Transportation Research Board Vol. 2269, No. 1 ( 2012-01), p. 58-64
    Details
    In: Transportation Research Record: Journal of the Transportation Research Board, SAGE Publications, Vol. 2269, No. 1 ( 2012-01), p. 58-64
    Abstract: The decisions of vehicular mode choice by businesses and commercial sectors in urban areas are addressed with attention to the unique trip-chaining behavior of commercial vehicles. Travel diary data from a collection of large-scale commercial vehicles in the Denver, Colorado, metropolitan area were used for analysis. Four types of travel activities were surveyed: business meetings, pickup and drop-off of people, pickup and delivery of cargo, and service calls. The survey results indicated that automobiles, pickup trucks, sport utility vehicles, single-unit trucks, and combination trucks were the main vehicular modes for travel with commercial purposes. The original survey data were sorted into trip-based and tour-based data sets for measuring commercial vehicle travel activities. A “trip” is defined as travel from one stop to another, and a “tour” is an entire travel journey starting from and ending at the home base of a vehicle with visits to various locations of interest. Discrete choice modeling techniques, particularly multinomial logit and nested logit models, were used to quantify the relationship between decisions on the choice of commercial vehicular mode and their affecting factors, and the two data sets were used separately. The modeling results indicate that mode choice by the commercial sector is travel specific, territory dependent, and cargo sensitive and varies by company. As proved by the comparison of trip-based and tour-based models, the tour is an intuitively and quantitatively better unit for measuring the travel activities of commercial vehicles and for modeling behavior of mode choice of the commercial sectors.
    Type of Medium: Online Resource
    ISSN: 0361-1981 , 2169-4052
    URL: Article
    DOI: 10.3141/2269-07
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2012
    detail.hit.zdb_id: 2403378-9
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    Online Resource
  • 4
    Online Resource
    Online Resource
    The Impact of Renal Impairment on Survival Outcomes in Patients With Metastatic Renal Cell Carcinoma Treated With Tyrosine Kinase Inhibitors
    SAGE Publications ; 2020
    In:  Cancer Control Vol. 27, No. 1 ( 2020-01-01), p. 107327482097714-
    Details
    In: Cancer Control, SAGE Publications, Vol. 27, No. 1 ( 2020-01-01), p. 107327482097714-
    Abstract: It remained unclear whether tyrosine kinase inhibitors (TKIs) related renal impairment had impact on the survival of patients with metastatic renal cell carcinoma (mRCC). Methods: Clinicopathological parameters of patients with mRCC treated with TKIs were retrospectively reviewed. Blood urea nitrogen (BUN), proteinuria and estimated glomerular filtration rate (eGFR) at baseline and during TKIs treatment were recorded. BUN 〉 7.1mol/L, eGFR 〈 60 ml/min/1.73m 2 and/or proteinuria level 〉 0.3 g/L were defined as renal impairment. eGFR and proteinuria were furtherly classified into different levels. Treatment outcomes were defined as progression-free survival (PFS) and overall survival (OS). Results: At baseline, the presence of abnormal BUN, eGFR and proteinuria level were observed in 25 (22.7%), 27 (25.5%) and 30 (27.3%) patients, which increased to 46 (41.8%), 55 (50.0%) and 64 (58.2%) respectively after TKIs treatment. In the whole cohort (N = 110), survival analysis suggested that only post-treatment renal impairment was related to survival outcomes. Interestingly, sub-analysis showed that post-treatment eGFR level (p = 0.004), proteinuria (p = 0.014) and eGFR decrease 〉 10% (p = 0.012) and elevated proteinuria compared with baseline (p = 0.006) were statistically correlated with OS among patients without RI at baseline (N = 51). On the contrary, deterioration of renal impairment after TKIs treatment in patients with renal impairment at baseline (N = 59) had no relationship with either PFS or OS. Furthermore, eGFR (p = 0.020) and eGFR decrease 〉 10% (p = 0.016) within 1 year after TKIs therapy were potential biomarkers for OS. Conclusion: Dynamic changes of TKI-induced RI during TKIs treatment, especially eGFR and proteinuria level, could be considered as potential biomarkers predicting survival outcomes of mRCC patients.
    Type of Medium: Online Resource
    ISSN: 1073-2748 , 1073-2748
    URL: Article
    DOI: 10.1177/1073274820977143
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2020
    detail.hit.zdb_id: 2004182-2
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