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  • 1
    Online Resource
    Online Resource
    SAGE Publications ; 2013
    In:  Tumori Journal Vol. 99, No. 2 ( 2013-03), p. 261-265
    In: Tumori Journal, SAGE Publications, Vol. 99, No. 2 ( 2013-03), p. 261-265
    Abstract: Hepatobiliary cystadenoma and cystadenocarcinoma are rare cystic lesions of the liver. The aim of the study was to discuss the clinical features, diagnostic methods and surgical treatment of hepatobiliary cystadenoma and cystadenocarcinoma in our hospital. Methods Six patients with hepatobiliary cystadenomas and four with hepatobiliary cystadenocarcinomas were evaluated. We collected detailed clinical data, and all patients were followed. Results Three patients of the 6 with cystadenomas and 2 patients of the 4 with cystadenocarcinomas had marked elevation of CA19-9 (average, 707.0 U/ml and 1078.5U/ml, respectively). CT scan with contrast revealed typical lesions in all 10 cases, i.e., cyst-occupying lesions with separations in the liver. All patients with hepatobiliary cystadenoma were treated by partial hepatectomy. None of them recurred at a mean follow-up of 40 months. Three patients with hepatobiliary cystadenocarcinoma underwent hepatectomy, without recurrence or metastasis at a mean follow-up of 32 months. Conclusions Tumor markers (CA19-9) and imaging findings may be helpful for an early diagnosis. Complete resection is still the best choice. Even for hepatobiliary cystadenocarcinoma, considering the low malignant grade, we suggest that for the best prognosis radical excision should be attempted.
    Type of Medium: Online Resource
    ISSN: 0300-8916 , 2038-2529
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2013
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    detail.hit.zdb_id: 2267832-3
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  • 2
    Online Resource
    Online Resource
    SAGE Publications ; 2016
    In:  Journal of Composite Materials Vol. 50, No. 1 ( 2016-01), p. 57-73
    In: Journal of Composite Materials, SAGE Publications, Vol. 50, No. 1 ( 2016-01), p. 57-73
    Abstract: A micromechanical stick-slip model was developed to characterize the damping response of single-walled carbon nanotube nanocomposites. Depending on the strength of the interfacial bonding and the extent of applied loading, the single-walled carbon nanotube embedded in the matrix may either completely stick to the matrix or partially slide relative to the matrix. The slippage in the interface, together with the contact friction, may lead to the energy dissipation of single-walled carbon nanotube nanocomposites. The effects of the aspect ratio of single-walled carbon nanotube, interfacial bonding strength, volume fraction of single-walled carbon nanotube, and interfacial friction on the damping behavior of single-walled carbon nanotube nanocomposites were accounted for in the micromechanical stick-slip model. In order to validate the analytical model, the energy dissipation was also evaluated using the finite element method. A cylindrical finite element method, with an embedded single-walled carbon nanotube, was developed where the stick-slip behavior of the interface between the single-walled carbon nanotube and surrounding matrix was characterized using a contact element. It was found that the energy dissipation obtained from the finite element analysis agrees with that derived from the micromechanical stick-slip model. Moreover, the energy dissipation may significantly increase, when the single-walled carbon nanotube slippage takes place. The increment of the energy dissipation could be attributed to the interfacial contact friction between the single-walled carbon nanotube and the surround matrix as well as the viscoelastic properties of the matrix materials.
    Type of Medium: Online Resource
    ISSN: 0021-9983 , 1530-793X
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2016
    detail.hit.zdb_id: 160490-9
    detail.hit.zdb_id: 2081924-9
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  • 3
    Online Resource
    Online Resource
    SAGE Publications ; 2016
    In:  Journal of Composite Materials Vol. 50, No. 27 ( 2016-11), p. 3779-3789
    In: Journal of Composite Materials, SAGE Publications, Vol. 50, No. 27 ( 2016-11), p. 3779-3789
    Abstract: The research investigated the thermal and mechanical properties of graphene/epoxy nanocomposites. Pristine graphene and functionalized graphene were used as nano-reinforcement in the nanocomposites. The graphene loadings employed in the nanocomposites were 0.1, 0.3, 0.5, and 1.0 wt%. The functional groups grafted on the functionalized graphene were characterized through Fourier transform infrared (FTIR) spectroscopy and X-ray photoelectron spectroscopy (XPS). Results indicated that two kinds of functional groups are grafted on the functionalized graphene surfaces: one contains only COOH group and the other contains both COOH and NH 2 groups. Moreover, from mechanical and thermal testing, it was found that the nanocomposites with functionalized graphene demonstrate better mechanical and thermal properties than those with pristine graphene. The graphene containing NH 2 and COOH functional groups exhibits superior mechanical and thermal properties than the graphene with only COOH functional group. In addition, Young’s modulus and thermal conductivity of the nanocomposites increase as the graphene loading increases. However, the fracture toughness and tensile strength of the nanocomposites attain peak values when the functionalized graphene loading is 0.1 wt%. The effects of the functional groups on the mechanical and thermal properties of nanocomposites were elaborated using molecular dynamics (MD) simulation. It was revealed that the interfacial thermal conductance and normalized interaction energy increase between the functionalized graphene and epoxy matrix, which may be responsible for the enhanced mechanical properties in the functionalized graphene/epoxy nanocomposites.
    Type of Medium: Online Resource
    ISSN: 0021-9983 , 1530-793X
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2016
    detail.hit.zdb_id: 160490-9
    detail.hit.zdb_id: 2081924-9
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  • 4
    Online Resource
    Online Resource
    SAGE Publications ; 2021
    In:  Journal of International Medical Research Vol. 49, No. 3 ( 2021-03), p. 030006052110017-
    In: Journal of International Medical Research, SAGE Publications, Vol. 49, No. 3 ( 2021-03), p. 030006052110017-
    Abstract: We present a case of an 81-year-old man with gallbladder gangrene after percutaneous vertebroplasty (PV) that was successfully treated via laparoscopic cholecystectomy (LC). The patient underwent multilevel, thoracic PV for painful osteoporotic compression fractures. PV performed at the T6 level was complicated by severe abdominal pain owing to direct embolization of the right T6 segmental artery with penetration of bone cement into the radicular artery beneath the pedicle. Cement leakage, especially arterial embolization of cement into the general circulation, is a known potential complication following PV. Serious complications related to PV augmentation procedures, such as vertebroplasty and kyphoplasty, are rare and most often result from local cement leakage or venous embolization. Combined with this case report, we reviewed the literature regarding the unusual occurrence of direct arterial cement embolization during PV and analyzed the causes to alert clinicians to this potentially rare vascular complication.
    Type of Medium: Online Resource
    ISSN: 0300-0605 , 1473-2300
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2021
    detail.hit.zdb_id: 2082422-1
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  • 5
    Online Resource
    Online Resource
    SAGE Publications ; 2019
    In:  Journal of Composite Materials Vol. 53, No. 6 ( 2019-03), p. 835-847
    In: Journal of Composite Materials, SAGE Publications, Vol. 53, No. 6 ( 2019-03), p. 835-847
    Abstract: Atomistic simulation together with micromechanical analysis was employed to characterize the Young’s modulus and thermal conductivity of graphene/epoxy nanocomposites. Nanocomposites containing pristine graphene, carboxyl (COOH)-functionalized graphene, and COOH- and amine (NH 2 )-functionalized graphene were considered in the simulations. The effect of atomistic interaction between the graphene and the surrounding epoxy was accounted for in the molecular dynamics simulations and then used to derive the effective properties of graphene. Subsequently, the Young’s modulus and thermal conductivity of nanocomposites containing randomly oriented graphene were modeled using the Mori–Tanaka micromechanical model. The results indicated that the COOH- and NH 2 -functionalized graphene nanocomposite had superior mechanical and thermal properties to the other two material systems. Moreover, the model predictions were in favorable agreement with the experimental data.
    Type of Medium: Online Resource
    ISSN: 0021-9983 , 1530-793X
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2019
    detail.hit.zdb_id: 160490-9
    detail.hit.zdb_id: 2081924-9
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  • 6
    In: Cell Transplantation, SAGE Publications, Vol. 30 ( 2021-01-01), p. 096368972110056-
    Abstract: Autotransfusion refers to a blood transfusion method in which the blood or blood components of the patient are collected under certain conditions, returned to himself when the patient needs surgery or emergency after a series of storing and processing. Although autotransfusion can avoid blood-borne diseases and adverse reactions related to allogeneic blood transfusion, a series of structural and functional changes of erythrocytes will occur during extension of storage time, thus affecting the efficacy of clinical blood transfusion. Our research was aimed to explore the change of erythrocyte oxygen-carrying capacity in different storage time, such as effective oxygen uptake (Q), P50, 2,3-DPG, Na + -K + -ATPase, to detect membrane potential, the change of Ca 2+ , and reactive oxygen species (ROS) change of erythrocytes. At the same time, Western blot was used to detect the expression of Mitofusin 1 (Mfn1) and Mitofusin 2 (Mfn2) proteins on the cytomembrane, from the perspective of oxidative stress to explore the function change of erythrocytes after different storage time. This study is expected to provide experimental data for further clarifying the functional status of erythrocytes with different preservation time in patients with autotransfusion, achieving accurate infusion of erythrocytes and improving the therapeutic effect of autologous blood transfusion, which has important clinical application value.
    Type of Medium: Online Resource
    ISSN: 0963-6897 , 1555-3892
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2021
    detail.hit.zdb_id: 2020466-8
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  • 7
    In: Clinical Rehabilitation, SAGE Publications
    Abstract: To assess the efficacy of injecting various amounts of fluid into the shoulder joints for capsule distension in patients with adhesive capsulitis. Design A randomized controlled trial. Setting Outpatient clinic of a tertiary care centre. Participants Eighty-four patients with adhesive capsulitis underwent a baseline (time0), 6 weeks (time1), and 12 weeks (time2) follow-up after hydrodilitation. Intervention Group 1 (n = 42) received 20 ml of lidocaine, steroid, and saline hydrodilatation via posterior glenohumeral recess, while Group 2 (n = 42) received 10 ml of lidocaine, steroid, and saline hydrodilitation. Main measures The primary outcome was the visual analogue scale for pain. The secondary outcomes were shoulder pain and disability index (SPADI) and ROM of the shoulder. Results There was a significant reduce in VAS scores for pain, SPADI scores, and increased shoulder ROM in both groups over time; however, the group-by-time interactions for any of the outcomes between groups were not significant except VAS pain in motion. Post-hoc pairwise analysis of the marginal effect of time and group showed that the significant difference of VAS in motion is due to time effect: time1 vs time0 (95% CI −4.09 to −2.68), time2 vs time0 (−4.21 to −2.77), and time2 vs time1 (−0.83 to 0.63), without between-group difference: group 1 vs group 2 (−0.38 to 0.59). Conclusion Our study suggests hydrodilatation achieved an optimal effect at time1 for patients with adhesive capsulitis in both groups, and adding more saline offers additional benefits in flexion and external roatation until time2.
    Type of Medium: Online Resource
    ISSN: 0269-2155 , 1477-0873
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2024
    detail.hit.zdb_id: 2028323-4
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  • 8
    Online Resource
    Online Resource
    SAGE Publications ; 2023
    In:  The American Journal of Sports Medicine Vol. 51, No. 3 ( 2023-03), p. 634-641
    In: The American Journal of Sports Medicine, SAGE Publications, Vol. 51, No. 3 ( 2023-03), p. 634-641
    Abstract: There are limited studies designed by matching related factors to compare clinical outcomes and return to sport (RTS) between patients undergoing revision anterior cruciate ligament reconstruction (R-ACLR) and primary ACLR (P-ACLR). Purpose: (1) To compare the outcomes between R-ACLR and P-ACLR in a matched-pair analysis with 3- to 5-year follow-up and (2) to evaluate patient-reported factors for not returning to preinjury-level sport. Study Design: Cohort study; Level of evidence, 4. Methods: Patients who underwent R-ACLR between September 2016 and November 2018 were propensity matched by age, sex, body mass index, passive anterior tibial subluxation, and generalized hypermobility in a 1:1 ratio to patients who underwent P-ACLR during the same period. By combining in person follow-up at 2 years postoperatively and telemedicine interview at the final follow-up (January 2022), knee stability and clinical scores were compared, including International Knee Documentation Committee (IKDC), Lysholm, and Tegner. Status of RTS was requested, specifically whether the patient returned to preinjury level of sport. Patient-reported reasons for not returning were analyzed. Results: There were 63 matched pairs in the present study. Knee stability was similar in terms of KT-2000 arthrometer, Lachman test, and pivot-shift test results between the groups at 2 years of follow-up. At the final follow-up, no significant difference was found between groups for postoperative clinical scores (IKDC, Tegner, and Lysholm) ( P 〉 .05). There was a significant difference in total RTS: 53 (84.1%) in the P-ACLR cohort and 41 (65.1%) in the R-ACLR cohort ( P = .014). No significant difference was shown in terms of RTS at the same level: 35 (55.6%) in P-ACLR and 31 (49.2%) in R-ACLR ( P = .476). Significantly more patients showed fear of reinjury: 26 of 32 (81.3%) in the R-ACLR group as compared with 15 of 28 (53.5%) in the P-ACLR group ( P 〈 .021). Conclusion: R-ACLR resulted in similar clinical scores (IKDC, Tegner, and Lysholm) but significantly lower RTS versus P-ACLR at 3 to 5 years of follow-up. Fear of reinjury was the most common factor that caused sport changes in patients with R-ACLR.
    Type of Medium: Online Resource
    ISSN: 0363-5465 , 1552-3365
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2023
    detail.hit.zdb_id: 2063945-4
    SSG: 31
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  • 9
    In: Lupus, SAGE Publications, Vol. 30, No. 6 ( 2021-05), p. 901-912
    Abstract: Our study purpose was to detect the distribution of anti-nuclear antibody (ANA) IgG subclasses in patients with systemic lupus erythematosus (SLE) and to evaluate their influence on the inflammatory process in SLE. Methods We determined the serum levels of ANA IgG subclasses from 70 SLE patients, 25 patients with other autoimmune diseases (OAD), and 25 healthy controls using ELISA. The serum level of total ANA IgG and the avidity of ANA IgG, dsDNA IgG, and dsDNA IgG subclasses were analysed by ELISA. Results The results indicated that levels of four ANA IgG subclasses (IgG1, IgG2, IgG3 and IgG4) and total IgG were significantly higher in SLE patients than in OAD patients and healthy controls ( p  〈  0.001). Moreover, the level of each ANA IgG subclass and the prevalence of high-avidity IgG ANAs (HA IgG ANAs) were significantly higher in the active cases than in the inactive cases of SLE and LN. Furthermore, level of ANA IgG subclasses decreased as level of dsDNA IgG subclasses decreased in 30 patients with SLE. In comparison, ANA IgG3 was significantly effective in high-dose prednisone combined with hydroxychloroquine ( p = 0.025). Additionally, it revealed that level of dsDNA IgG had a significant influence on four ANA IgG subclasses, especially on ANA IgG3 (β coefficient = 0.649, p  〈  0.001). Level of ANA IgG3 was also positively related to the serum level of dsDNA IgG (r = 0.729, p  〈  0.001) and RAI of HA IgG ANAs (r = 0.504, p  〈  0.001). However, the level of ANA IgG4 was positively related to the serum level of albumin (r = 0.572, p  〈  0.001) and RAI of HA IgG ANAs (r = 0.549, p  〈  0.001). Moreover, the results revealed that cutaneous and renal involvement were mainly associated with the ANA IgG1 and IgG4 subclasses. Although, arthritic involvement was mainly associated with ANA IgG3. Conclusions First, we demonstrated that the ANA IgG subclasses were diagnostic tools in SLE patients. Furthermore, HA IgG ANAs might affect the distribution of ANA IgG3 and IgG4. Moreover, ANA IgG3 might play a particular role in the activity of SLE disease and therapy. Therefore, an altered ANA IgG subclass distribution might be a risk factor influencing the inflammatory process in SLE.
    Type of Medium: Online Resource
    ISSN: 0961-2033 , 1477-0962
    RVK:
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2021
    detail.hit.zdb_id: 2008035-9
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  • 10
    Online Resource
    Online Resource
    SAGE Publications ; 2018
    In:  The International Journal of Biological Markers Vol. 33, No. 4 ( 2018-11), p. 407-414
    In: The International Journal of Biological Markers, SAGE Publications, Vol. 33, No. 4 ( 2018-11), p. 407-414
    Abstract: Lysine-specific demethylase 2A (KDM2A), a specific H3K36me1/2 demethylase, has been reported to be closely associated with several types of cancer. In this study, we aimed to investigate the expression and function of KDM2A in colorectal adenocarcinoma. Methods: A total of 215 colorectal adenocarcinoma specimens were collected, and then subjected to immunohistochemistry assay to evaluate the expression levels of KDM2A, cyclin D1 and other proteins in colorectal adenocarcinoma tissues. Real-time polymerase chain reaction, Western blot, and other molecular biology methods were used to explore the role of KDM2A in colorectal adenocarcinoma cells. Results: In this study, we report that the expression level of KDM2A is high in colorectal adenocarcinoma tissues, and this high expression promotes the proliferation and colony formation of colorectal adenocarcinoma cells, as demonstrated by KDM2A knockdown experiments. In addition, the expression of KDM2A is closely associated with cyclin D1 expression in colorectal adenocarcinoma tissues and cell lines. Conclusions: Our study reveals a novel role for high-expressed KDM2A in colorectal adenocarcinoma cell growth, and that the expression of KDM2A is associated with that of cyclin D1 in colorectal adenocarcinoma.
    Type of Medium: Online Resource
    ISSN: 1724-6008 , 1724-6008
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2018
    detail.hit.zdb_id: 1475778-3
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