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  • 1
    Online Resource
    Online Resource
    A Novel ID-Based Authentication and Key Exchange Protocol Resistant to Ephemeral-Secret-Leakage Attacks for Mobile Devices
    SAGE Publications ; 2015
    In:  International Journal of Distributed Sensor Networks Vol. 11, No. 5 ( 2015-05-01), p. 898716-
    Details
    In: International Journal of Distributed Sensor Networks, SAGE Publications, Vol. 11, No. 5 ( 2015-05-01), p. 898716-
    Abstract: With the rapid development in wireless communications and cloud computing technologies, clients (users) often use handheld mobile devices to access remote servers via open network channels. To provide authentication and confidentiality between clients and servers, a large number of ID-based authentication and key exchange (ID-AKE) protocols have been proposed for mobile client-server environments. However, most of the existing ID-AKE protocols adopt the precomputation technique so that they become vulnerable to the ephemeral-secret-leakage (ESL) attacks, in the sense that an adversary could use the ephemeral secrets to reveal the private keys of clients from the corresponding exchange messages. In the paper, we propose a new ESL-secure ID-AKE protocol for mobile client-server environments. We formally prove that the proposed protocol satisfies the security requirements of both mutual authentication and key exchange while resisting the ESL attacks. When compared with previously proposed ID-AKE protocols, our protocol has higher security and retains computational performance, since it requires no bilinear pairing operation for mobile clients. Finally, we mention the possibility of adopting our protocol as an authentication method of the extensible authentication protocol (EAP) for wireless networks.
    Type of Medium: Online Resource
    ISSN: 1550-1477 , 1550-1477
    URL: Article
    DOI: 10.1155/2015/898716
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2015
    detail.hit.zdb_id: 2192922-1
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  • 2
    Online Resource
    Online Resource
    Comparison of the effect of clarithromycin triple therapy with or without N -acetylcysteine in the eradication of Helicobacter pylori : a randomized controlled trial
    SAGE Publications ; 2020
    In:  Therapeutic Advances in Gastroenterology Vol. 13 ( 2020-01), p. 175628482092730-
    Details
    In: Therapeutic Advances in Gastroenterology, SAGE Publications, Vol. 13 ( 2020-01), p. 175628482092730-
    Abstract: Whether adjunctive N-acetylcysteine (NAC) may improve the efficacy of triple therapy in the first-line treatment of Helicobacter pylori infection remains unknown. Our aim was to compare the efficacy of 14-day triple therapy with or without NAC for the first-line treatment of H. pylori. Material and methods: Between 1 January 2014 and 30 June 2018, 680 patients with H. pylori infection naïve to treatment were enrolled in this multicenter, open-label, randomized trial. Patients were randomly assigned to receive triple therapy with NAC [NAC-T14, dexlansoprazole 60 mg four times daily (q.d.); amoxicillin 1 g twice daily (b.i.d.), clarithromycin 500 mg b.i.d., NAC 600 mg b.i.d.] for 14 days, or triple therapy alone (T14, dexlansoprazole 60 mg q.d.; amoxicillin 1 g b.i.d., clarithromycin 500 mg b.i.d.) for 14 days. Our primary outcome was the eradication rates by intention to treat (ITT). Antibiotic resistance and CYP2C19 gene polymorphism were determined. Results: The ITT analysis demonstrated H. pylori eradication rates in NAC-T14 and T14 were 81.7% [276/338, 95% confidence interval (CI): 77.5–85.8%] and 84.3% (285/338, 95% CI 80.4–88.2%), respectively. In 646 participants who adhered to their assigned therapy, the eradication rates were 85.7% and 88.0% with NAC-T14 and T14 therapies, respectively. There were no differences in compliance or adverse effects. The eradication rates in subjects with clarithromycin-resistant, amoxicillin-resistant, or either clarithromycin/amoxicillin resistant strains were 45.2%, 57.9%, and 52.2%, respectively, for NAC-T14, and were 66.7%, 76.9%, and 70.0%, respectively, for T14. The efficacy of NAC-T14 and T14 was not affected by CYP2C19 polymorphism. Conclusion: Add-on NAC to triple therapy was not superior to triple therapy alone for first-line H. pylori eradication [ClinicalTrials.gov identifier: NCT02249546].
    Type of Medium: Online Resource
    ISSN: 1756-2848 , 1756-2848
    URL: Article
    DOI: 10.1177/1756284820927306
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2020
    detail.hit.zdb_id: 2440710-0
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  • 3
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    Online Resource
    Using a telemedicine-assisted airway model to improve the communication and teamwork of tracheal intubation during the coronavirus disease 2019 pandemic
    SAGE Publications ; 2022
    In:  Journal of Telemedicine and Telecare
    Details
    In: Journal of Telemedicine and Telecare, SAGE Publications
    Abstract: Isolated spaces impair communication and teamwork during tracheal intubation (TI) in suspected coronavirus disease 2019 patients. We thus aimed to evaluate the telemedicine-assisted airway model (TAM) to improve communication and teamwork during the pandemic. Methods This two-stage prospective study included adult patients intubated in the emergency department of the National Taiwan University Hospital between 1 August 2020 and 31 July 2021. First, we randomised patients receiving TI in the standard setting into the conventional group (Con-G) and the isolation area into the isolation group (Iso-G). We evaluated the obstacles to communication and teamwork in an isolation scenario. Second, we developed the TAM to facilitate communication and teamwork between staff in separate spaces during TI and assigned patients to the TAM group (TAM-G). Communication and teamwork were evaluated using the Team Emergency Assessment Measure (TEAM). Subjective evaluations were conducted using a questionnaire administered to medical staff. Results Eighty-nine patients were enrolled: 17, 34, and 38 in the Con-G, Iso-G, and TAM-G, respectively. The communication frequency (CF) of the Con-G and Iso-G was the highest and lowest, respectively. The CF of the TAM-G increased and approached that of the Con-G. The overall TEAM score was the highest in the Con-G and the lowest in the Iso-G, while the overall score in the TAM-G was comparable to that of the Con-G. Discussion The TAM may improve communication and teamwork for TIs without compromising efficacy during the pandemic. This study was registered at ClinicalTrials.gov; registration numbers: NCT04479332 and NCT04591873.
    Type of Medium: Online Resource
    ISSN: 1357-633X , 1758-1109
    URL: Article
    DOI: 10.1177/1357633X221124175
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2022
    detail.hit.zdb_id: 2007700-2
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  • 4
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    Online Resource
    Dynamic simulation of the SLOWPOKE-3 nuclear heating reactor
    SAGE Publications ; 1985
    In:  SIMULATION Vol. 44, No. 4 ( 1985-04), p. 181-188
    Details
    In: SIMULATION, SAGE Publications, Vol. 44, No. 4 ( 1985-04), p. 181-188
    Abstract: A 2 MWth nuclear reactor, called SLOWPOKE-3 (Safe LOW- POwer Critical Experiment), is being developed at the Chalk River Nuclear Laboratories (CRNL). This pool-type reactor is cooled by natural circulation and is designed to produce hot water for commercial space heating and perhaps generate some electricity. It is intended for remote locations where the costs of alternative forms of energy are high. A dynamic simulation of this reactor, without closed-loop con trol, was developed and implemented on a hybrid computer, using the basic equations of reactor kinetics and of conserva tion of mass, energy and momentum. The natural circulation of downcomer flow in the pool was simulated using a special filter, capable of modeling various flow conditions. The simula tion was then used to study the intermediate and long-term tran sient response of SLOWPOKE-3 to large disturbances, such as loss of heat sink, loss of regulation, daily load following, and over- cooling of the reactor coolant. Results of the simulation show that the reactor is inherently stable and self-regulating and that none of these disturbances produce hazardous transients.
    Type of Medium: Online Resource
    ISSN: 0037-5497 , 1741-3133
    URL: Article
    DOI: 10.1177/003754978504400403
    RVK:
    SA 7910
    Language: English
    Publisher: SAGE Publications
    Publication Date: 1985
    detail.hit.zdb_id: 2072208-4
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  • 5
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    Online Resource
    Upregulation of LGALS1 is associated with oral cancer metastasis
    SAGE Publications ; 2018
    In:  Therapeutic Advances in Medical Oncology Vol. 10 ( 2018-01), p. 175883591879462-
    Details
    In: Therapeutic Advances in Medical Oncology, SAGE Publications, Vol. 10 ( 2018-01), p. 175883591879462-
    Abstract: Oral cancer metastasis is a devastating process that contributes to poor prognosis and high mortality, yet its detailed underlying mechanisms remain unclear. Here, we aimed to evaluate metastasis-specific markers in oral cancer and to provide comprehensive recognition concerning functional roles of the specific target in oral cancer metastasis. Methods: Lectin, galactoside-binding, soluble, 1 (LGALS1) was identified by secretomic analysis. LGALS1 expression of patient samples with oral cancer on the tissue microarray were examined by immunochemical (IHC) staining. Small interfering RNA (siRNA)-mediated knockdown of LGALS1 revealed the role of LGALS1 in oral cancer metastasis in vitro and in vivo. Results: LGALS1 was observed to be upregulated in highly invasive oral cancer cells, and elevated LGALS1 expression was correlated with cancer progression and lymph node metastasis in oral cancer tissue specimens. Functionally, silencing LGALS1 resulted in suppressed cell growth, wound healing, cell migration, and cell invasion in oral cancer cells in vitro. Knockdown of LGALS1 in highly invasive oral cancer cells dramatically inhibited lung metastasis in an in vivo mouse model. Mechanistic studies suggested p38 mitogen-activated protein kinase (MAPK) phosphorylation, upregulated MMP-9, and mesenchymal phenotypes of epithelial-mesenchymal transition (EMT) in highly invasive oral cancer cells, whereas siRNA against LGALS1 resulted in the inactivation of p38 MAPK pathway, downregulated MMP-9, and EMT inhibition. Conclusions: These findings demonstrate that elevated LGALS1 is strongly correlated with oral cancer progression and metastasis, and that it could potentially serve as a prognostic biomarker and an innovative target for oral cancer therapy.
    Type of Medium: Online Resource
    ISSN: 1758-8359 , 1758-8359
    URL: Article
    DOI: 10.1177/1758835918794622
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2018
    detail.hit.zdb_id: 2503443-1
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  • 6
    Online Resource
    Online Resource
    Positive Mood as a Mediator of the Relations among Musical Preference, Postconsumption Product Evaluation, and Consumer Satisfaction
    SAGE Publications ; 2007
    In:  Psychological Reports Vol. 100, No. 3 ( 2007-06), p. 927-938
    Details
    In: Psychological Reports, SAGE Publications, Vol. 100, No. 3 ( 2007-06), p. 927-938
    Abstract: This study of how positive mood mediates the influences of musical preference and postconsumption product evaluation on consumer satisfaction focuses specifically on a model in which positive mood fully mediates the influences. The proposed model is compared with two competing models, and a structural equation model is used to test and compare the three theory-driven models. This study sampled 247 students majoring in management at a single university. They had mean age of 23 yr. ( SD = 2.5). This study used questionnaires to measure subjects' evaluations of a cup of coffee, preference for the music broadcast in the coffee shop, positive mood, and satisfaction after they had the coffee. Analysis indicated that the proposed model outperformed the two competing models in describing the data using chi-square difference tests. Positive mood was identified as a full mediator of the relationship between musical preference and consumer satisfaction. Moreover, the results demonstrate for service managers the importance of creating positive consumer mood.
    Type of Medium: Online Resource
    ISSN: 0033-2941 , 1558-691X
    URL: Article
    DOI: 10.2466/pr0.100.3.927-938
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2007
    detail.hit.zdb_id: 2066930-6
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  • 7
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    Reduced global brain metabolism but maintained vascular function in amnestic mild cognitive impairment
    SAGE Publications ; 2017
    In:  Journal of Cerebral Blood Flow & Metabolism Vol. 37, No. 4 ( 2017-04), p. 1508-1516
    Details
    In: Journal of Cerebral Blood Flow & Metabolism, SAGE Publications, Vol. 37, No. 4 ( 2017-04), p. 1508-1516
    Abstract: Amnestic mild cognitive impairment represents an early stage of Alzheimer’s disease, and characterization of physiological alterations in mild cognitive impairment is an important step toward accurate diagnosis and intervention of this condition. To investigate the extent of neurodegeneration in patients with mild cognitive impairment, whole-brain cerebral metabolic rate of oxygen in absolute units of µmol O 2 /min/100 g was quantified in 44 amnestic mild cognitive impairment and 28 elderly controls using a novel, non-invasive magnetic resonance imaging method. We found a 12.9% reduction ( p = 0.004) in cerebral metabolic rate of oxygen in mild cognitive impairment, which was primarily attributed to a reduction in the oxygen extraction fraction, by 10% ( p = 0.016). Global cerebral blood flow was not found to be different between groups. Another aspect of vascular function, cerebrovascular reactivity, was measured by CO 2 -inhalation magnetic resonance imaging and was found to be equivalent between groups. Therefore, there seems to be a global, diffuse diminishment in neural function in mild cognitive impairment, while their vascular function did not show a significant reduction.
    Type of Medium: Online Resource
    ISSN: 0271-678X , 1559-7016
    URL: Article
    DOI: 10.1177/0271678X16658662
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2017
    detail.hit.zdb_id: 2039456-1
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  • 8
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    Online Resource
    Entecavir versus Lamivudine in the Treatment of Chronic Hepatitis B Patients with Hepatic Decompensation
    SAGE Publications ; 2012
    In:  Antiviral Therapy Vol. 17, No. 4 ( 2012-05), p. 605-612
    Details
    In: Antiviral Therapy, SAGE Publications, Vol. 17, No. 4 ( 2012-05), p. 605-612
    Abstract: Lamivudine has been widely used in chronic hepatitis B patients with hepatic decompensation, but its use is limited by drug resistance. This outcome research aimed to investigate the comparative efficacy and safety of entecavir versus lamivudine in decompensated patients. Methods Between November 2004 and February 2010, 126 consecutive treatment-naive patients received either entecavir ( n=53) or lamivudine ( n=73) for decompensated chronic hepatitis B. All patients presented with both hyperbilirubinaemia and coagulopathy. Primary outcome was mortality within 1 year; secondary outcomes included liver-related mortality, biochemical and virological response, and improvement of hepatic dysfunction. Results Both treatment groups were comparable in baseline characteristics. A total of 19 (35.8%) entecavir and 33 (45.2%) lamivudine receivers expired within 1 year, respectively ( P=0.29, log rank test). Age (hazard ratio [HR] 1.04 per year, 95% CI 1.01, 1.06), cirrhosis (HR 2.07, 95% CI 1.02, 4.23), and international normalized ratio for prothrombin time (HR 1.44, 95% CI 1.20, 1.74) were independent baseline predictors for all-cause mortality. Antiviral therapy was also unrelated to liver-specific death. However, more patients taking entecavir tended to attain aminotransferase normalization (76.5% versus 52.5%; P=0.05) and viral DNA undetectability (100% versus 58.3%; P=0.06). Moreover, entecavir was associated with significantly greater reduction of the model for end-stage liver disease scores (median 10.0 versus 4.3; P=0.02). Overall, 3 (7.5%) lamivudine but no entecavir users acquired drug resistance in 1 year ( P=0.25). Conclusions Entecavir as compared with lamivudine is similar in the effect on short-term mortality but is associated with greater clinical improvement among chronic hepatitis survivors who recovered from hepatic decompensation.
    Type of Medium: Online Resource
    ISSN: 1359-6535 , 2040-2058
    URL: Article
    DOI: 10.3851/IMP2027
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2012
    detail.hit.zdb_id: 2118396-X
    SSG: 15,3
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  • 9
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    Circadian Activity Rhythms and Sleep in Nurses Working Fixed 8-hr Shifts
    SAGE Publications ; 2015
    In:  Biological Research For Nursing Vol. 17, No. 3 ( 2015-05), p. 348-355
    Details
    In: Biological Research For Nursing, SAGE Publications, Vol. 17, No. 3 ( 2015-05), p. 348-355
    Abstract: Shift work is associated with adverse health outcomes. The aim of this study was to explore the effects of shift work on circadian activity rhythms (CARs) and objective and subjective sleep quality in nurses. Female day-shift ( n = 16), evening-shift ( n = 6), and night-shift ( n = 13) nurses wore a wrist actigraph to monitor the activity. We used cosinor analysis and time–frequency analysis to study CARs. Night-shift nurses exhibited the lowest values of circadian rhythm amplitude, acrophase, autocorrelation, and mean of the circadian relative power (CRP), whereas evening-shift workers exhibited the greatest standard deviation of the CRP among the three shift groups. That is, night-shift nurses had less robust CARs and evening-shift nurses had greater variations in CARs compared with nurses who worked other shifts. Our results highlight the importance of assessing CARs to prevent the adverse effects of shift work on nurses’ health.
    Type of Medium: Online Resource
    ISSN: 1099-8004 , 1552-4175
    URL: Article
    DOI: 10.1177/1099800414549454
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2015
    detail.hit.zdb_id: 2070503-7
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  • 10
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    The Team Climate Inventory (TCI) : A Psychometric Test on a Taiwanese Sample of Work Groups
    SAGE Publications ; 2009
    In:  Small Group Research Vol. 40, No. 4 ( 2009-08), p. 465-482
    Details
    In: Small Group Research, SAGE Publications, Vol. 40, No. 4 ( 2009-08), p. 465-482
    Abstract: Understanding the feasibility of applying the Team Climate Inventory (TCI) in non-Western cultures is essential for researchers attempting to understand the influence of culture on workers' perceived climate. This study describes the application of the TCI in such a setting using data from 203 administrators employed in a Taiwanese medical center. Reliability and factor analyses were performed to establish the feasibility and psychometric properties of the TCI Taiwan version. Reliabilities of both the four- and five-factor solutions exceeded .80. Factor analyses indicated a satisfactory four-factor structure, despite some variations in comparison with the U.K. version. The TCI Taiwan version is feasible and has acceptable psychometric properties. Further research is warranted regarding the degree to which disparities result from cultural differences and the specific nature of organizational systems in Chinese communities.
    Type of Medium: Online Resource
    ISSN: 1046-4964 , 1552-8278
    URL: Article
    DOI: 10.1177/1046496409334145
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2009
    detail.hit.zdb_id: 2030802-4
    SSG: 5,2
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