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  • SAGE Publications  (10)
  • 1
    In: Journal of International Medical Research, SAGE Publications, Vol. 47, No. 8 ( 2019-08), p. 3905-3917
    Abstract: To evaluate the safety and cost of early discharge compared with ordinary discharge in patients with diabetes mellitus (DM) following percutaneous coronary intervention (PCI) for acute coronary syndrome. Methods We performed a retrospective analysis of prospectively collected data from 474 patients with DM who were discharged from hospital following PCI at a regional center between 2012 and 2015. Results A total of 192 patients (40.5%) were included in the early discharge group and 282 patients (59.5%) were included in the ordinary group. Mortality and morbidity after PCI were recorded. Kaplan–Meier analysis showed similar prognosis between the two groups at 30 days and at 1 year after discharge. However, hospitalization expenses for the regular discharge group were significantly higher than those of the early discharge group (RMB65,750 vs. RMB50,983). Conclusion Our findings demonstrate that early discharge of patients with DM following PCI for acute coronary syndrome is safe compared with ordinary discharge, and may reduce hospitalization costs.
    Type of Medium: Online Resource
    ISSN: 0300-0605 , 1473-2300
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2019
    detail.hit.zdb_id: 2082422-1
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  • 2
    Online Resource
    Online Resource
    SAGE Publications ; 2018
    In:  Journal of Reinforced Plastics and Composites Vol. 37, No. 3 ( 2018-02), p. 181-190
    In: Journal of Reinforced Plastics and Composites, SAGE Publications, Vol. 37, No. 3 ( 2018-02), p. 181-190
    Type of Medium: Online Resource
    ISSN: 0731-6844 , 1530-7964
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2018
    detail.hit.zdb_id: 2051886-9
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  • 3
    Online Resource
    Online Resource
    SAGE Publications ; 2023
    In:  Proceedings of the Institution of Mechanical Engineers, Part D: Journal of Automobile Engineering
    In: Proceedings of the Institution of Mechanical Engineers, Part D: Journal of Automobile Engineering, SAGE Publications
    Abstract: Accurate and rapid braking pressure regulation in electric pneumatic braking systems (EPBS) is vital to vehicle safety. Due to the switching behaviors of the on-off solenoid valves, the operation of the EPBS shows a hybrid nature with both continuous variables and discrete events, which raises the hybrid control problem. One of the possible solutions is to employ the hybrid model predictive controller with the mixed logical dynamical (MLD) model based on the linear approximation of the system dynamics. However, the nonlinearity and complexity of the EPBS make the MLD model obtained by linearizing the system equations directly require high storage and computing capacity. To address these issues, this article presents a practical hybrid model predictive controller based on the system dynamics simplified expressions considering the EPBS pressure variations caused by on-off solenoid valve states at the current sampling time and the last sampling time. The relationship between the pressure variations and the on-off solenoid valve states is first studied by the system mathematical model, followed by applying the mixed logic dynamical modeling approach to establish the hybrid model of the pressure continuous dynamics with discrete features of on-off solenoid valves. Based on these, a hybrid model predictive controller is formulated to solve the EPBS pressure control problem. The simulations and bench experiments are carried out to verify the controller. Besides, an existing model predictive control (MPC) controller is compared with the proposed controller. All the results demonstrate the effectiveness of the hybrid model predictive controller.
    Type of Medium: Online Resource
    ISSN: 0954-4070 , 2041-2991
    RVK:
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2023
    detail.hit.zdb_id: 2032754-7
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  • 4
    Online Resource
    Online Resource
    SAGE Publications ; 2019
    In:  Dose-Response Vol. 17, No. 3 ( 2019-07), p. 155932581987258-
    In: Dose-Response, SAGE Publications, Vol. 17, No. 3 ( 2019-07), p. 155932581987258-
    Abstract: Docetaxel (DTX) is commonly used for breast cancer treatment. Tween 80 used for DTX dissolution in its clinical formulation causes severe hypersensitivity and other adverse reactions. In this study, trastuzumab (Tmab)-coated lipid-polymer hybrid nanoparticles (PLNs) were prepared, composed of poly (d, l-lactide- co-glycolide), PLGA; polyethylenimine (PEI); and lipids. The PLGA/PEI/lipid formed a hydrophobic core, while Tmab was electrostatically adsorbed on the surface of the PLNs as a ligand that targets human epidermal growth factor receptor 2 (HER2)-positive breast cancer cells. The resulting PLNs, electrostatically adsorbed Tmab-bearing PLGA/PEI/lipid nanoparticles (eTmab-PPLNs), had a mean particle size of 217.4 ± 13.36 nm, a ζ potential of 0.056 ± 0.315 mV, and good stability. In vitro, the eTmab-PPLNs showed increased cytotoxicity in HER2-postive BT474 cells but not in HER2-negative MCF7 cells. Studies of the ability of eTmab-PPLNs to target HER2 were performed. The uptake of eTmab-PPLNs was shown to be dependent on HER2 expression level. Therefore, eTmab-PPLNs provide a promising therapeutic for the treatment of breast cancer.
    Type of Medium: Online Resource
    ISSN: 1559-3258 , 1559-3258
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2019
    detail.hit.zdb_id: 2440820-7
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  • 5
    Online Resource
    Online Resource
    SAGE Publications ; 2012
    In:  Proceedings of the Institution of Mechanical Engineers, Part N: Journal of Nanoengineering and Nanosystems Vol. 226, No. 1 ( 2012-03), p. 27-30
    In: Proceedings of the Institution of Mechanical Engineers, Part N: Journal of Nanoengineering and Nanosystems, SAGE Publications, Vol. 226, No. 1 ( 2012-03), p. 27-30
    Abstract: A novel electrospinning, which is characterized by low driven voltage threshold and ease to expand production rate, is demonstrated by using a probe tip to touch and withdraw from the surface of a polyethylene oxide solution with speed of about 1 m/s, to issue a jet. Thus nanofibers are obtained on the collector. The experiment results show that the spinning period increases with increasing applied voltage and the process eventually becomes continuous as the applied voltage reaches more than 31 kV. The effect of applied voltage on the diameter of the nanofibers is also discussed. Such method will open a new door to achieve massive production of nanofibers.
    Type of Medium: Online Resource
    ISSN: 1740-3499 , 2041-3092
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2012
    detail.hit.zdb_id: 2197969-8
    detail.hit.zdb_id: 2961164-7
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  • 6
    In: High Performance Polymers, SAGE Publications, Vol. 32, No. 6 ( 2020-08), p. 631-644
    Abstract: The 3-allyl-5,5-dimethylhydantoin (ADMH) was synthesized and characterized by Fourier transform infrared spectroscopy, 1 H-nuclear magnetic resonance (NMR), and 13 C-NMR spectroscopy. Then, the ADMH was used to modify the N, N′-(4,4′-diphenylmethane)bismaleimide (BDM)/2,2′-diallylbisphenol A (DABPA) resin to obtain the BDM/DABPA/ADMH resin system (BDA). The curing behavior was investigated by non-isothermal differential scanning calorimetry and the activation energy ([Formula: see text]) was obtained by Kissinger and Ozawa models. The thermomechanical property was measured by dynamic mechanical analysis. Analysis of the data revealed the complexity of the curing reaction, which was firstly dominated by the Ene reaction of allyl and C=C double bond at low and medium temperatures and was further governed by the Diels–Alder reaction and the anionic imide oligomerization occurred at high temperatures. The results demonstrated that 1-BDA had the best thermal and mechanical properties exhibiting excellent modification effect of ADMH.
    Type of Medium: Online Resource
    ISSN: 0954-0083 , 1361-6412
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2020
    detail.hit.zdb_id: 1483713-4
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  • 7
    Online Resource
    Online Resource
    SAGE Publications ; 2017
    In:  Advances in Mechanical Engineering Vol. 9, No. 9 ( 2017-09), p. 168781401772869-
    In: Advances in Mechanical Engineering, SAGE Publications, Vol. 9, No. 9 ( 2017-09), p. 168781401772869-
    Type of Medium: Online Resource
    ISSN: 1687-8140 , 1687-8140
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2017
    detail.hit.zdb_id: 2501620-9
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  • 8
    Online Resource
    Online Resource
    SAGE Publications ; 2020
    In:  Proceedings of the Institution of Mechanical Engineers, Part B: Journal of Engineering Manufacture Vol. 234, No. 12 ( 2020-10), p. 1473-1485
    In: Proceedings of the Institution of Mechanical Engineers, Part B: Journal of Engineering Manufacture, SAGE Publications, Vol. 234, No. 12 ( 2020-10), p. 1473-1485
    Abstract: Mg-based metal matrix composites reinforced with nanoparticles are promising biomaterials due to their biocompatibility and high hardness and because they are local and systemic toxicity free. Nano-metal matrix composites are considered to be hard-to-machine materials due to the high strength and high abrasiveness of the reinforcing nanoparticles. In this article, the micro-drilling mechanisms of Mg-based metal matrix composites reinforced with different volume fraction of SiO 2 nanoparticles (0.5, 1.0, 1.5, 2.0 vol.%) were investigated experimentally. Results obtained were also compared with pure Mg. First, it was found that the volume fraction and drilling parameters played an important role in the chip formation mechanism. Second, the influence of drilling parameters on hole surface morphology and cutting force were studied, in which both the rotation speed and feedrate affected the surface morphology, and the main factor affecting cutting force was found to be the feedrate. Furthermore, the formation of burrs was investigated. The height of the burr could be reduced by using small feedrate and low rotation speed. Finally, the size effect of micro-drilling was studied. The variation of surface roughness and cutting force of pure Mg and Mg-based metal matrix composites had three changing trends with the uncut chip thickness. The minimum chip thickness of Mg/SiO 2 metal matrix composites was determined to be 1.1 μm.
    Type of Medium: Online Resource
    ISSN: 0954-4054 , 2041-2975
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2020
    detail.hit.zdb_id: 2032745-6
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  • 9
    In: Textile Research Journal, SAGE Publications
    Abstract: This study endeavors to elucidate the salient factors that influence the efficacy of roller-based robotic manipulators in grasping multi-layered flaky deformation objects in a planar configuration. Through a rigorous force analysis of the grasping process, it was ascertained that the manipulation of flaky deformation objects is influenced by four forces. Subsequent analysis of the genesis of these forces enabled the identification of four pivotal factors: the applied downward pressure, the location of grasp, the number of stacked layers, and the coefficient of friction. To gain a comprehensive understanding of how these factors dictate the grasping efficacy, a series of meticulously designed experiments was conducted. The findings reveal that augmenting the coefficient of friction between the roller and fabric, intensifying the downward pressure, increasing the number of stacked layers, and opting for a grasp location proximal to the edge significantly bolster the success rate of grasping. These revelations hold the potential to furnish theoretical guidance for optimizing the grasping strategies of roller-based robotic manipulators under practical operational conditions.
    Type of Medium: Online Resource
    ISSN: 0040-5175 , 1746-7748
    RVK:
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2024
    detail.hit.zdb_id: 2209596-2
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  • 10
    Online Resource
    Online Resource
    SAGE Publications ; 2020
    In:  Advanced Composites Letters Vol. 29 ( 2020-01-01), p. 2633366X2094277-
    In: Advanced Composites Letters, SAGE Publications, Vol. 29 ( 2020-01-01), p. 2633366X2094277-
    Abstract: The distribution and conduction path of lightning current inside carbon fiber-reinforced polymer (CFRP) composites subjected to lightning strikes are determined by their dynamic conductive characteristics. An experimental platform that generates lightning current impulses with variable parameters was established to obtain the equivalent conductivities of CFRPs with different laminated structures. The experimental results indicated that the through-thickness conductivity (10 −3 S/mm) was much lower than the in-plane conductivity (10 0 S/mm). Then, the dynamic conduction model of CFRPs was analyzed based on the anisotropic nonlinear conductivities of CFRPs under lightning currents of 50–1000 A. The CFRP laminate could be regarded as a series circuit of resistance and inductance. The dynamic conductance of the CFRP laminate first increased and then decreased during the single lightning current strike process, which was closely related to the conductive properties of the interlaminar resin. The inductive properties of the CFRP material were manifested in the test results, which showed that the voltage reached the peak value prior to the current waveform and the equivalent conductivities of the CFRPs increased as the rate of increase decreased and the duration increased. In addition, the equivalent inductance of the carbon fiber network was found to be an important part of the inductive effect of CFRP laminates. This research is helpful for understanding the complicated relationships in the lightning current conducting process and can provide experimental and theoretical support for CFRP coupled electrical–thermal simulation studies of lightning direct effects.
    Type of Medium: Online Resource
    ISSN: 2633-366X , 2633-366X
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2020
    detail.hit.zdb_id: 3053419-7
    detail.hit.zdb_id: 2144398-1
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