GLORIA

GEOMAR Library Ocean Research Information Access

X

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Online Resource
    Online Resource
    Book Review: Validity: Theoretical Development and Integrated Arguments
    SAGE Publications ; 2021
    In:  Language Testing Vol. 38, No. 4 ( 2021-10), p. 636-639
    Details
    In: Language Testing, SAGE Publications, Vol. 38, No. 4 ( 2021-10), p. 636-639
    Type of Medium: Online Resource
    ISSN: 0265-5322 , 1477-0946
    URL: Article
    DOI: 10.1177/02655322211007770
    RVK:
    EQ 1000
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2021
    detail.hit.zdb_id: 999075-6
    detail.hit.zdb_id: 2023709-1
    SSG: 7,11
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 2
    Online Resource
    Online Resource
    Use of Miniplates and Local Bone Grafts to Prevent Spring Back in Laminoplasty for Cervical Spondylotic Myelopathy
    SAGE Publications ; 2016
    In:  Journal of Orthopaedics, Trauma and Rehabilitation Vol. 20, No. 1 ( 2016-06), p. 24-29
    Details
    In: Journal of Orthopaedics, Trauma and Rehabilitation, SAGE Publications, Vol. 20, No. 1 ( 2016-06), p. 24-29
    Abstract: Cervical spondylotic myelopathy/ossification of posterior longitudinal ligament can be treated by anterior or posterior decompression. For multiple levels, it is common to perform posterior decompression by laminoplasty. Hirabayashi described his open-door expansive laminoplasty in 1977, which soon became popular. Spring back of the lamina has always been a problem. Many methods including suturing to soft tissue, suture anchors, bone grafts, hydroxyapatite blocks, and ceramic spacers were used to prevent this problem, but with considerable failure. Recently, miniplates were used to prevent spring back. Methods Twenty-nine consecutive patients who had underwent Hirabayashi open-door expansive laminoplasty in a single centre were recruited in this retrospective study. Miniplates were used to keep the laminae open. In addition, the spinous processes of lower cervical vertebrae were excised and used as local bone grafts to fill the gap between the cut laminae. Computerized tomography scans were performed postoperatively for all patients to assess bone union and spring back. Results A total of 126 levels of laminoplasty and 51 local bone grafts were studied. The minimal follow-up period was 12 months. Signs of bone union were demonstrated in 123 hinges (97.6%) and 51 bone grafts (100%). No spring back was detected. The clinical outcome in terms of Hirabayashi recovery rate was 47.2%. Conclusion Miniplates and local bone grafts are promising and effective tools for preventing spring back in cervical laminoplasty.
    Type of Medium: Online Resource
    ISSN: 2210-4917 , 2210-4925
    URL: Article
    DOI: 10.1016/j.jotr.2015.06.005
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2016
    detail.hit.zdb_id: 2588336-7
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 3
    Online Resource
    Online Resource
    The role of miR-92b in cholangiocarcinoma patients
    SAGE Publications ; 2018
    In:  The International Journal of Biological Markers Vol. 33, No. 3 ( 2018-08), p. 293-300
    Details
    In: The International Journal of Biological Markers, SAGE Publications, Vol. 33, No. 3 ( 2018-08), p. 293-300
    Abstract: The role of microRNA (miRNA) in cholangiocarcinoma was not clear. The aim of this study was to find the potential diagnostic and prognostic miRNA in cholangiocarcinoma patients. Methods: The miRNA expression profiles in cholangiocarcinoma patients from The Cancer Genome Atlas and Gene Expression Omnibus (GSE53870) were analyzed. The comparison of overall survival was performed using the Kaplan–Meier method. The targeted genes of prognostic miRNA were identified in miRanda, PicTar, or TargetScan, and their cell signaling pathways were analyzed by the Database for Annotation, Visualization and Integrated Discovery. Results: In The Cancer Genome Atlas and the Gene Expression Omnibus miRNA dataset, miR-92b and miR-99a were found with concordant directionality, up-regulated and down-regulated, respectively. In The Cancer Genome Atlas survival data, patients with the high level of miR-99b had obviously shorter overall survival time ( P=0.038). However, the level of miR-99a was not found to be significant. The 17 shared target genes of miR-92b were identified, such as DAB21IP, BCL21L11, SPHK2, PER2, and TSC1. The related pathways included positive regulation of transcription, positive regulation of cellular biosynthetic process, regulation of programmed cell death, etc. Conclusion: miR-92b was up-regulated in cholangiocarcinoma compared with normal controls. The high level of miR-92b was associated with adverse outcomes in cholangiocarcinoma patients, which might be partly explained by the targeted genes of miR-92b and their signaling pathways.
    Type of Medium: Online Resource
    ISSN: 1724-6008 , 1724-6008
    URL: Article
    DOI: 10.1177/1724600817751524
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2018
    detail.hit.zdb_id: 1475778-3
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 4
    Online Resource
    Online Resource
    Longitudinal Changes in Resting-State Brain Activity in a Capsular Infarct Model
    SAGE Publications ; 2015
    In:  Journal of Cerebral Blood Flow & Metabolism Vol. 35, No. 1 ( 2015-01), p. 11-19
    Details
    In: Journal of Cerebral Blood Flow & Metabolism, SAGE Publications, Vol. 35, No. 1 ( 2015-01), p. 11-19
    Abstract: Strokes attributable to subcortical infarcts have been increasing recently in elderly patients. To gain insight how this lesion influences the motor outcome and responds to rehabilitative training, we used circumscribed photothrombotic capsular infarct models on 36 Sprague-Dawley rats (24 experimental and 12 sham-operated). We used 2-deoxy-2-[ 18 F]-fluoro-D-glucose-micro positron emission tomography (FDG-microPET) to assess longitudinal changes in resting-state brain activity (rs-BA) and daily single-pellet reaching task (SPRT) trainings to evaluate motor recovery. Longitudinal FDG-microPET results showed that capsular infarct resulted in a persistent decrease in rs-BA in bilateral sensory and auditory cortices, and ipsilesional motor cortex, thalamus, and inferior colliculus ( P 〈 0.0025, false discovery rate (FDR) q 〈 0.05). The decreased rs-BA is compatible with diaschisis and contributes to manifest the malfunctions of lesion-specific functional connectivity. In contrast, capsular infarct resulted in increase of rs-BA in the ipsilesional internal capsule, and contralesional red nucleus and ventral hippocampus in recovery group ( P 〈 0.0025, FDR q 〈 0.05), implying that remaining subcortical structures have an important role in conducting the recovery process in capsular infarct. The SPRT training facilitated motor recovery only in rats with an incomplete destruction of the posterior limb of the internal capsule (PLIC) (Pearson's correlation, P 〈 0.05). Alternative therapeutic interventions are required to enhance the potential for recovery in capsular infarct with complete destruction of PLIC.
    Type of Medium: Online Resource
    ISSN: 0271-678X , 1559-7016
    URL: Article
    DOI: 10.1038/jcbfm.2014.178
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2015
    detail.hit.zdb_id: 2039456-1
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 5
    Online Resource
    Online Resource
    Enhanced acidogenic fermentation of food waste in a continuous-flow reactor
    SAGE Publications ; 2002
    In:  Waste Management & Research: The Journal for a Sustainable Circular Economy Vol. 20, No. 2 ( 2002-04), p. 110-118
    Details
    In: Waste Management & Research: The Journal for a Sustainable Circular Economy, SAGE Publications, Vol. 20, No. 2 ( 2002-04), p. 110-118
    Abstract: This study was performed to improve acidogenic fermentation of food waste in a continuous-flow reactor. The fermentation of food waste is affected by the fermentation constraints such as the biodegradability of substrate, the degrading capability of microorganisms and the environmental conditions. The key factors were, therefore, examined to control the fermentation constraints, such as the effect of seed inoculation and the effect of adjusting dilution rate. Acidogenic fermentation of food waste employing rumen microorganisms resulted in the enhanced efficiency (71.2%) as compared with that (59.8%) employing mesophilic acidogens. In addition, the fermentation efficiency increased from 71.2 to 82.0% by adjusting dilution rate from 3.0 to 1.0 d -1 depending on the state of the fermentation. The main component of the acidified product was shifted from butyric to acetic acid. This meant that the increase of the fermentation efficiency was mainly caused by the enhanced degradation of vegetables and meats. The control of the fermentation constraints was, therefore, very effective in improving the fermentation efficiency of food waste.
    Type of Medium: Online Resource
    ISSN: 0734-242X , 1096-3669
    URL: Article
    DOI: 10.1177/0734242X0202000202
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2002
    detail.hit.zdb_id: 1480483-9
    detail.hit.zdb_id: 46937-3
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 6
    Online Resource
    Online Resource
    Optimizing Classification Decision Trees by Using Weighted Naïve Bayes Predictors to Reduce the Imbalanced Class Problem in Wireless Sensor Network
    SAGE Publications ; 2013
    In:  International Journal of Distributed Sensor Networks Vol. 9, No. 1 ( 2013-01-01), p. 460641-
    Details
    In: International Journal of Distributed Sensor Networks, SAGE Publications, Vol. 9, No. 1 ( 2013-01-01), p. 460641-
    Abstract: Standard classification algorithms are often inaccurate when used in a wireless sensor network (WSN), where the observed data occur in imbalanced classes. The imbalanced data classification problem occurs when the number of samples in one class, usually the class of interest, is much lower than the number in the other classes. Many classification models have been studied in the data-mining research community. However, they all assume that the input data are stationary and bounded in size, so that resampling techniques and postadjustment by measuring the classification cost can be applied. In this paper, we devise a new scheme that extends a popular stream classification algorithm to the analysis of WSNs for reducing the adverse effects of the imbalanced class in the data. This new scheme is resource light at the algorithm level and does not require any data preprocessing. It uses weighted naïve Bayes predictors at the decision tree leaves to effectively reduce the impact of imbalanced classes. Experiments show that our modified algorithm outperforms the original stream classification algorithm.
    Type of Medium: Online Resource
    ISSN: 1550-1477 , 1550-1477
    URL: Article
    DOI: 10.1155/2013/460641
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2013
    detail.hit.zdb_id: 2192922-1
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 7
    Online Resource
    Online Resource
    A Randomized Placebo-Controlled, Dose-Finding Study of Oral Lb80380 in Hbeag-Positive Patients with Chronic Hepatitis B
    SAGE Publications ; 2006
    In:  Antiviral Therapy Vol. 11, No. 8 ( 2006-11), p. 977-984
    Details
    In: Antiviral Therapy, SAGE Publications, Vol. 11, No. 8 ( 2006-11), p. 977-984
    Abstract: LB80380 is potent antiviral agent against hepatitis B virus (HBV) in vitro and in the woodchuck model. It has an excellent preclinical safety profile including lower potential for renal toxicity than adefovir. It is effective against both wild-type and YMDD mutant HBV. LB80380 is converted to its parent drug, LB80331, after oral absorption, and further metabolized to its active form, LB80317. Aims/Methods This randomized placebo-controlled Phase I/II clinical study of LB80380 was conducted to assess the safety, antiviral activity and pharmacokinetics of its parent drug LB80331 and its active form LB80317 in 29 Asian adults with chronic hepatitis B positive for hepatitis B e antigen in four escalating dose groups (30, 60, 120 and 240 mg once per day) for 4 weeks with a 12-week follow-up period. Results The mean maximum HBV DNA reduction was 3.05, 4.20, 3.67 and 3.68 log 10 copies/ml for 30, 60, 120 and 240 mg per day, respectively. Viral dynamic analysis suggested a high degree of inhibition of HBV replication at doses of 60 mg or higher per day. LB80380 was well tolerated at all dose groups, and no dose-related clinical or laboratory adverse event was reported. Conclusion LB80380 is shown to be a potent and safe antiviral agent for HBV. Marked HBV DNA suppression was observed in all dose groups. The HBV DNA suppression was approximately constant at doses of 60 mg and higher over the 28-day dosing period. The dose response of LB80380 will be evaluated further in large clinical studies.
    Type of Medium: Online Resource
    ISSN: 1359-6535 , 2040-2058
    URL: Article
    DOI: 10.1177/135965350601100806
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2006
    detail.hit.zdb_id: 2118396-X
    SSG: 15,3
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 8
    Online Resource
    Online Resource
    〈I〉TLR4 Asp299Gly 〈/I〉 and〈I〉 Thr399Ile 〈/I〉 polymorphisms are very rare in the Chinese population
    SAGE Publications ; 2004
    In:  Journal of Endotoxin Research Vol. 10, No. 4 ( 2004-08-01), p. 238-240
    Details
    In: Journal of Endotoxin Research, SAGE Publications, Vol. 10, No. 4 ( 2004-08-01), p. 238-240
    Type of Medium: Online Resource
    ISSN: 0968-0519 , 1743-2839
    URL: Article
    DOI: 10.1179/096805104225005841
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2004
    detail.hit.zdb_id: 2381250-3
    detail.hit.zdb_id: 2041941-7
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 9
    Online Resource
    Online Resource
    Combustion performance and stability of a dual-fuel diesel–natural-gas engine
    SAGE Publications ; 2015
    In:  Proceedings of the Institution of Mechanical Engineers, Part D: Journal of Automobile Engineering Vol. 229, No. 2 ( 2015-02), p. 235-246
    Details
    In: Proceedings of the Institution of Mechanical Engineers, Part D: Journal of Automobile Engineering, SAGE Publications, Vol. 229, No. 2 ( 2015-02), p. 235-246
    Abstract: Experimental investigations on the combustion performance and the stability of a dual-fuel engine fuelled with diesel and natural gas were conducted. The effects of the pilot diesel quantity and the pilot diesel injection timing were analysed. The results show that the maximum (peak) in-cylinder pressure increases and appears earlier with increasing pilot diesel quantity. The heat release rate has two peaks during the process of combustion. Earlier pilot diesel injection resulted in an earlier pressure evolution and a higher peak in-cylinder pressure. Correspondingly, the ignition of the pilot diesel was advanced and the heat release rate of diesel ignition increases. Earlier diesel injection timing increases the diesel combustion heat release, and the combustion of the whole charge in cylinder is more drastic. The pilot diesel quantities have different effects on the cycle-by-cycle variations (i.e. the coefficient of variation). At a low load, both very high and very low pilot diesel quantities lead to a high coefficient of variation in the indicated mean effective pressure, and the effect becomes weaker with increasing load. The coefficient of variation in the indicated mean effective pressure decreases and the coefficient of variation in the the peak in-cylinder pressure increases with increasing load. Additionally, the coefficient of variation in the indicated mean effective pressure decreases as the pilot diesel injection was advanced. The largest value of the coefficient of variation in the peak in-cylinder pressure occurs at 20° crank angle before top dead centre. The maximum rate of pressure rise increases dramatically with earlier pilot diesel injection timing. Nitrogen oxide emissions increase and hydrocarbon emissions decrease with increasing pilot diesel quantity. The hydrocarbon emissions decrease at earlier diesel injection timing; however, the nitrogen oxide emissions increase.
    Type of Medium: Online Resource
    ISSN: 0954-4070 , 2041-2991
    URL: Article
    DOI: 10.1177/0954407014537814
    RVK:
    ZO 4200
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2015
    detail.hit.zdb_id: 2032754-7
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 10
    Online Resource
    Online Resource
    Polyetherketone powder/epoxy blends with low viscosity and high mechanical properties
    SAGE Publications ; 2020
    In:  High Performance Polymers Vol. 32, No. 9 ( 2020-11), p. 1052-1060
    Details
    In: High Performance Polymers, SAGE Publications, Vol. 32, No. 9 ( 2020-11), p. 1052-1060
    Abstract: The difficult forming process and construction caused by high viscosity has been the main problem restricting the application of high-performance thermoplastic/epoxy blends. In this contribution, low viscous polyetherketone (PEK)/diglycidyl ether of bisphenol A epoxy resin (DGEBA) blends were prepared by mixing the ultrafine PEK powder and DGEBA monomer at ambient temperature. Rheological behaviour shows that complex viscosity of the undissolved blends containing 20 wt% PEK powder is two orders of magnitude lower than that of the dissolved one. Interestingly, diffusion and phase separation of PEK powder in the undissolved PEK/DGEBA/2-methylimidazole/dicyandiamide (M-DICY) blends are affected by the curing processes. Phase-inverted morphology was observed after curing at 120°C/1h + 160°C/0.5 h for the undissolved 20 wt% PEK/DGEBA/M-DICY blends which also exhibited outstanding tensile strength and lap shear strength both at 298 and 77 K. We believe this work should provide a new insight into the preparation of advanced thermoplastic/epoxy blends.
    Type of Medium: Online Resource
    ISSN: 0954-0083 , 1361-6412
    URL: Article
    DOI: 10.1177/0954008320931578
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2020
    detail.hit.zdb_id: 1483713-4
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...