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  • SAGE Publications  (6)
  • 1
    In: Journal of Orthopaedic Surgery, SAGE Publications, Vol. 25, No. 2 ( 2017-05), p. 230949901771393-
    Type of Medium: Online Resource
    ISSN: 2309-4990 , 2309-4990
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2017
    detail.hit.zdb_id: 2128854-9
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  • 2
    In: Journal of Orthopaedic Surgery, SAGE Publications, Vol. 28, No. 3 ( 2020-05-01), p. 230949902097521-
    Abstract: The study aimed to develop an evidence-based expert consensus statement on diagnosis and treatment of cervical ossification posterior longitudinal ligament (OPLL). Method: Delphi method was used to perform such survey, and the panel members from Asia Pacific Spine Society (APSS) 2020 were invited to answer the open-ended questions in rounds 1 and 2. Then the results were summarized and developed into a Likert-style questionnaire for voting in round 3, and the level of agreement was defined as 80%. In the whole process, we conducted a systematic literature search on evidence for each statement. Results: Cervical OPLL can cause various degrees of neurological symptoms, an it’s thought to be more common in Asia population. CT reconstruction is an important imaging examination to assist diagnosis and guide surgical choice. Segmental, continuous, mixed, and focal type is the most widely used classification system. The non-surgical treatment is recommended for patients with no or mild clinical symptoms, or irreversible neurological damage, or failed surgical decompression, or condition cannot tolerant surgery, or refusing surgery. As OPLL may continue to develop gradually, surgical treatment would be considered in their course inevitably. The surgical choice should depend on various conditions, such as involved levels, thickness, and type of OPLL, skill-experiences of surgeons, which are listed and discussed in the article. Conclusion: In this statement, we describe the clinical features, classifications, and diagnostic criteria of cervical OPLL, and review various surgical methods (such as their indications, complications), and provide a guideline on their choice strategy.
    Type of Medium: Online Resource
    ISSN: 2309-4990 , 2309-4990
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2020
    detail.hit.zdb_id: 2128854-9
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  • 3
    Online Resource
    Online Resource
    SAGE Publications ; 2019
    In:  Journal of International Medical Research Vol. 47, No. 12 ( 2019-12), p. 6041-6052
    In: Journal of International Medical Research, SAGE Publications, Vol. 47, No. 12 ( 2019-12), p. 6041-6052
    Abstract: The factors that influence cognitive function in patients with atrial fibrillation (AF) remain unclear. Methods This study involved an AF group and control group (normal sinus rhythm) of 150 patients each. Cognitive function was assessed with the adjusted Mini-Mental State Examination (MMSEadj) score and Memory and Executive Screening (MES) score. The relationship between cognitive function and the CHA 2 DS 2 VASc score was analyzed. Subgroup analysis was performed according to stroke history. Clinical factors affecting the MMSE score were screened by logistic regression analysis. Results Baseline data were similar between the two groups. The MMSEadj and MES scores were significantly lower in the AF than control group; the mean MMSEadj score in the AF non-stroke subgroup and control non-stroke subgroup was 26.2 ± 2.7 and 27.9 ± 2.0, respectively. In non-stroke patients with AF, the MMSEadj and MES scores were negatively correlated with the CHA 2 DS 2 VASc score. Factors significantly influencing the MMSE score in these patients were age, education, smoking history, NT-proB-type natriuretic peptide, hemoglobin, and anticoagulation. Conclusion AF is associated with cognitive dysfunction regardless of stroke history. High CHA 2 DS 2 VASc scores are associated with impaired cognitive function. Factors influencing cognitive function in non-stroke patients with AF are age, education, smoking history, NT-proB-type natriuretic peptide, hemoglobin, and anticoagulation.
    Type of Medium: Online Resource
    ISSN: 0300-0605 , 1473-2300
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2019
    detail.hit.zdb_id: 2082422-1
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  • 4
    Online Resource
    Online Resource
    SAGE Publications ; 2017
    In:  Neurorehabilitation and Neural Repair Vol. 31, No. 10-11 ( 2017-10), p. 898-909
    In: Neurorehabilitation and Neural Repair, SAGE Publications, Vol. 31, No. 10-11 ( 2017-10), p. 898-909
    Abstract: Carpal tunnel syndrome (CTS) is a most common peripheral nerve entrapment neuropathy characterized by sensorimotor deficits in median nerve innervated digits. Block-design task-related functional magnetic resonance imaging (fMRI) studies have been used to investigate CTS-related neuroplasticity in the primary somatosensory cortices. However, considering the persistence of digital paresthesia syndrome caused by median nerve entrapment, spontaneous neuronal activity might provide a better understanding of CTS-related neuroplasticity, which remains unexplored. The present study aimed to investigate both local and extensive spontaneous neuronal activities with resting-state fMRI. A total of 28 bilateral CTS patients and 24 normal controls were recruited, and metrics, including amplitude of low-frequency fluctuation (ALFF) and voxel-wise functional connectivity (FC), were used to explore synaptic activity at different spatial scales. Correlations with clinical measures were further investigated by linear regression. Decreased amplitudes of low-frequency fluctuation were observed in the bilateral primary sensory cortex (SI) and secondary sensory cortex (SII) in CTS patients (AlphaSim corrected P 〈 .05). This was found to be negatively related to the sensory thresholds of corresponding median nerve innervated fingers. In the voxel-wise FC analysis, with predefined seed regions of interest in the bilateral SI and primary motor cortex, we observed decreased interhemispheric and increased intrahemispheric FC. Additionally, both interhemispheric and intrahemispheric FC were found to be significantly correlated with the mean ALFF.
    Type of Medium: Online Resource
    ISSN: 1545-9683 , 1552-6844
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2017
    detail.hit.zdb_id: 2100545-X
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  • 5
    Online Resource
    Online Resource
    SAGE Publications ; 1999
    In:  Asian Cardiovascular and Thoracic Annals Vol. 7, No. 3 ( 1999-09), p. 173-176
    In: Asian Cardiovascular and Thoracic Annals, SAGE Publications, Vol. 7, No. 3 ( 1999-09), p. 173-176
    Abstract: This prospective randomized study was undertaken to test the hypothesis that ischemic preconditioning could improve myocardial protection with cold blood cardioplegia in patients undergoing valve replacement and to investigate the mechanism of ischemic preconditioning in human myocardium. After the institution of cardiopulmonary bypass, 20 patients undergoing double valve replacement were preconditioned with 2 cycles of 3 minutes of aortic crossclamping and 2 minutes of reperfusion before cardioplegic arrest. A further 20 patients served as controls. The hearts were arrested with blood cardioplegic solution at 4°C. In the perioperative period, blood samples were collected from the coronary sinus, samples of right atrial myocardial tissue were obtained, and cardiac function was measured. Ischemic preconditioning reduced oxygen free radial production, calcium overload, and myocardial ultrastructural damage, while the myocardial production of calcitonin gene-related peptide was increased to 95.3 ± 3.8 μg·L −1 compared with 61.2 ± 4.9 μg·L −1 in the controls. Cardiac index was also higher in the preconditioned patients at 2.8 L·min −1 ·m −2 compared to 2.3 L·min −1 ·m −2 in the controls. It was concluded that ischemic preconditioning enhanced cardioplegic protection in valve replacement patients by increasing the level of calcitonin gene-related peptide and decreasing oxygen free radicals.
    Type of Medium: Online Resource
    ISSN: 0218-4923 , 1816-5370
    Language: English
    Publisher: SAGE Publications
    Publication Date: 1999
    detail.hit.zdb_id: 2044527-1
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  • 6
    Online Resource
    Online Resource
    SAGE Publications ; 2016
    In:  HAND Vol. 11, No. 1_suppl ( 2016-09), p. 24S-24S
    In: HAND, SAGE Publications, Vol. 11, No. 1_suppl ( 2016-09), p. 24S-24S
    Abstract: Purpose: Phrenic nerve transfer (PNT) has proven to be an effective approach for the treatment of brachial plexus avulsion injuries (BPAI). But there have been major concerns about the possibility of deterioration of the pulmonary and diaphragm functions after PNT. In the current study, we performed end-to-side neurorrhaphy in PNT for BPAI patients while minimizing the potential damage to the diaphragm function. We prospectively assessed the efficacy of end-to-side neurorrhaphy for PNT in reconstructing the elbow flexion by regenerating the anterior division of the upper trunk (ADUT) or the musculocutaneous nerve (McN) in a series of 5 patients. Methods: From January to June 2008, 5 patients with BPAI underwent PNT with an end-to-side fashion, to regenerate the ADUT (3 patients) or the McN (2 patients). The operative delay after injury was from 1 to 6 months (mean, 2.5 months). The follow-up duration was 24 months. The regeneration outcomes of ADUT or McN were evaluated with an electromyography (EMG) test. The recovery of elbow flexion power was recorded according to the British Medical Research Council (MRC) grading system. Pulmonary function tests (PFTs) were used to assess the respiratory function. Chest fluoroscopy and phrenic nerve conduction studies were performed in the evaluation of phrenic nerve and diaphragm functions. Results: At the final visits after 2 years, all patients regained various degrees of biceps strength (M4 in 2 patients, M3 in 1 patient, M2 in 1 patient, and M1 in 1 patient). At 24 months after surgery, the average prolongation of latency of PN was 2.88 seconds, and the average decrease in amplitude from before the operation was 32.4%. The diaphragm function and PFTs were normal in all patients. Conclusions: PNT with end-to-side neurorrhaphy could provide functional biceps recovery in a majority of patients, with preservation of donor nerve function.
    Type of Medium: Online Resource
    ISSN: 1558-9447 , 1558-9455
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2016
    detail.hit.zdb_id: 2316440-2
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