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  • 1
    Online Resource
    Online Resource
    The Japan HOspice and Palliative Care Evaluation Study (J-HOPE Study): Views About Legalization of Death With Dignity and Euthanasia Among the Bereaved Whose Family Member Died at Palliative Care Units
    SAGE Publications ; 2009
    In:  American Journal of Hospice and Palliative Medicine® Vol. 26, No. 2 ( 2009-04), p. 98-104
    Details
    In: American Journal of Hospice and Palliative Medicine®, SAGE Publications, Vol. 26, No. 2 ( 2009-04), p. 98-104
    Abstract: There has been a debate in appropriateness of legalization of death with dignity and euthanasia in Japan. To clarify views about these issues, we conducted a large nationwide study of the bereaved whose family member died at palliative care units. The percentages of 429 bereaved family members (response rate 65%) who affirmed legal authorization were 52 for death with dignity and 45 for euthanasia and who affirmed assignment at the discretion of the physician involved were 37 for death with dignity and 38 for euthanasia. In conclusion, views about legalization of death with dignity and euthanasia among the bereaved are inconsistent. No consensus is reached as to legislation of these issues.
    Type of Medium: Online Resource
    ISSN: 1049-9091 , 1938-2715
    URL: Article
    DOI: 10.1177/1049909108327027
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2009
    detail.hit.zdb_id: 2236674-X
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  • 2
    Online Resource
    Online Resource
    Contrast-enhanced synthetic MRI for the detection of brain metastases
    SAGE Publications ; 2016
    In:  Acta Radiologica Open Vol. 5, No. 2 ( 2016-02-01), p. 205846011562675-
    Details
    In: Acta Radiologica Open, SAGE Publications, Vol. 5, No. 2 ( 2016-02-01), p. 205846011562675-
    Abstract: Synthetic magnetic resonance imaging (MRI), a technique that enables creation of various contrast-weighted images from a single MRI quantification scan, is a useful clinical tool. However, there are currently no reports examining the use of contrast-enhanced synthetic MRI for detecting brain metastases. Purpose To assess whether contrast-enhanced synthetic MRI is suitable for detecting brain metastases. Material and Methods Ten patients with a combined total of 167 brain metastases who underwent quantitative MRI and conventional T1-weighted inversion recovery fast spin-echo (conventional T1IR) MRI before and after administration of a contrast agent were included in the study. Synthetic T1IR and T1-weighted (synthetic T1W) images were produced after parameter quantification. Lesion-to-white matter contrast and contrast-to-noise ratio were calculated for each image. The number of visible lesions in each image was determined by two neuroradiologists. Results The mean lesion-to-white matter contrast and mean contrast-to-noise ratio of the synthetic T1IR images were significantly higher than those of the synthetic T1W ( P  〈  0.001 and P  〈  0.001, respectively) and conventional T1IR ( P = 0.04 and P = 0.002, respectively) images. Totals of 130 and 124 metastases were detected in the synthetic T1IR images by the first and second radiologists, respectively. The corresponding numbers were 91 and 85 in the synthetic T1W images and 119 and 119 in the conventional T1IR images. Statistical significance was not found among detected numbers of lesions. Conclusion Synthetic T1IR imaging created better contrast compared with synthetic T1W or conventional T1IR imaging. The ability to detect brain metastases was comparable among these imaging.
    Type of Medium: Online Resource
    ISSN: 2058-4601 , 2058-4601
    URL: Article
    DOI: 10.1177/2058460115626757
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2016
    detail.hit.zdb_id: 2818429-4
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  • 3
    Online Resource
    Online Resource
    Propensity score matching analysis for adverse events of EUS-guided biliary drainage in advanced elderly patients (PEACE study)
    SAGE Publications ; 2022
    In:  Therapeutic Advances in Gastroenterology Vol. 15 ( 2022-01), p. 175628482210926-
    Details
    In: Therapeutic Advances in Gastroenterology, SAGE Publications, Vol. 15 ( 2022-01), p. 175628482210926-
    Abstract: Several studies have suggested that elderly patients, as well as younger patients, can be safely treated using endoscopic retrograde cholangiopancreatography (ERCP). However, endoscopic ultrasound-guided biliary drainage (EUS-BD) has not been clinically evaluated for very elderly patients. The present multicenter, retrospective study aimed to determine the safety of EUS-BD for advanced elderly patients. Method: Patients who underwent EUS-BD during this period were retrospectively enrolled, and they were divided into two groups based on age: group A (age   〈  75 years) and group B (age ⩾ 75). In this study, capnographic monitoring was used only for elderly patients (age ⩾ 75 years). Results: A total of 271 patients who underwent EUS-BD were enrolled in this study (group A = 177, group B = 94). The types of adverse events that were associated with EUS-BD was observed in 38 patients, and they did not differ significantly between two groups ( p = 0.855). This result was confirmed after propensity score matching ( p = 0.510). Adverse events were associated with sedation after propensity score matching; hypoxemia ( p = 0.012) and severe hypoxemia ( p = 0.003) were significantly higher in group A compared with group B. According to logistic regression analysis, monitoring (non-capnography) was also only risk factor (odds ratio: 0.317, 95% confidence interval: 0.143–0.705; p = 0.005) for sedation-related adverse events. Conclusion: In conclusion, EUS-BD could be safety performed in advanced elderly patients, the same as in younger patients. Also, capnographic monitoring might be helpful in case of sedation by a gastroenterologist in a non-intubated patient. Further prospective, randomized studies are needed to confirm these conclusions.
    Type of Medium: Online Resource
    ISSN: 1756-2848 , 1756-2848
    URL: Article
    DOI: 10.1177/17562848221092612
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2022
    detail.hit.zdb_id: 2440710-0
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  • 4
    Online Resource
    Online Resource
    The relationship between top management team diversity and organizational resilience: Evidence from the automotive industry in Japan
    SAGE Publications ; 2023
    In:  Journal of General Management Vol. 48, No. 2 ( 2023-01), p. 184-194
    Details
    In: Journal of General Management, SAGE Publications, Vol. 48, No. 2 ( 2023-01), p. 184-194
    Abstract: Organizational resilience has attracted much attention with regard to a company’s survival and to achieve higher performance in today’s uncertain conditions. However, how organizational resilience is built remains unclear. This study sheds light on the function of the top management team (TMT) from upper echelons theory and argues that its deep-level diversity has a positive impact on organizational resilience. Our empirical study of the Japanese automotive industry found that tenure, international, and wise diversity have a positive impact on building organizational resilience. In contrast, educational background diversity was found to have a negative impact on building organizational resilience, contrary to our hypothesis. Our results revealed that diversity was a double-edged sword and established the need to focus on environmental and industrial contexts in linking diversity and organizational resilience. Further elucidation of the relationship between diversity and organizational resilience can be achieved by simultaneously focusing on other aspects of diversity, in concurrence with existing diversity indices for variety.
    Type of Medium: Online Resource
    ISSN: 0306-3070 , 1759-6106
    URL: Article
    DOI: 10.1177/03063070221081202
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2023
    detail.hit.zdb_id: 2068265-7
    SSG: 3,2
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  • 5
    Online Resource
    Online Resource
    Coherent Anti-Stokes Raman Scattering Spectroscopy Using a Double-Wavelength-Emission Electronically Tuned Ti:Sapphire Laser
    SAGE Publications ; 2021
    In:  Applied Spectroscopy Vol. 75, No. 8 ( 2021-08), p. 988-993
    Details
    In: Applied Spectroscopy, SAGE Publications, Vol. 75, No. 8 ( 2021-08), p. 988-993
    Abstract: Coherent anti-Stokes Raman scattering (CARS) spectroscopy is a powerful tool for Raman imaging technology. In contrast, conventional spontaneous Raman spectroscopy is often used for biological analysis with multivariate analysis. This study develops a new type of CARS instrument with a double-wavelength-emission, background-free, electronically tuned Ti:sapphire laser (DW-ETL). DW-ETL generates two laser pulses with different wavelengths simultaneously within its single resonator. The pulse wavelength and buildup time are regulated by acousto-optical tunable filter in the resonator. The present DW-ETL CARS system is free from any mechanical movement to measure a CARS spectrum by controlling each laser pulse of the emission throughout the fingerprint region. Consequently, it is theoretically able to provide stable CARS spectra to apply multivariate analysis in biological applications. The present study demonstrates that the DW-ETL CARS system provides spectra of biomedical samples in the full finger-print region, and the stability and controllability of the system are evaluated.
    Type of Medium: Online Resource
    ISSN: 0003-7028 , 1943-3530
    URL: Article
    DOI: 10.1177/00037028211020313
    RVK:
    VA 2367
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2021
    detail.hit.zdb_id: 1474251-2
    SSG: 11
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