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  • 1
    In: Neurorehabilitation and Neural Repair, SAGE Publications, Vol. 34, No. 9 ( 2020-09), p. 814-830
    Abstract: Although rehabilitation is beneficial for individuals with traumatic brain injury (TBI), a significant proportion of them do not receive adequate rehabilitation after acute care. Objective Therefore, the goal of this prospective and multicenter study was to investigate predictors of access to rehabilitation in the year following injury in patients with TBI. Methods Data from a large European study (CENTER-TBI), including TBIs of all severities between December 2014 and December 2017 were used (N = 4498 patients). Participants were dichotomized into those who had and those who did not have access to rehabilitation in the year following TBI. Potential predictors included sociodemographic factors, psychoactive substance use, preinjury medical history, injury-related factors, and factors related to medical care, complications, and discharge. Results In the year following traumatic injury, 31.4% of patients received rehabilitation services. Access to rehabilitation was positively and significantly predicted by female sex (odds ratio [OR] = 1.50), increased number of years of education completed (OR = 1.05), living in Northern (OR = 1.62; reference: Western Europe) or Southern Europe (OR = 1.74), lower prehospital Glasgow Coma Scale score (OR = 1.03), higher Injury Severity Score (OR = 1.01), intracranial (OR = 1.33) and extracranial (OR = 1.99) surgery, and extracranial complication (OR = 1.75). On contrast, significant negative predictors were lack of preinjury employment (OR = 0.80), living in Central and Eastern Europe (OR = 0.42), and admission to hospital ward (OR = 0.47; reference: admission to intensive care unit) or direct discharge from emergency room (OR = 0.24). Conclusions Based on these findings, there is an urgent need to implement national and international guidelines and strategies for access to rehabilitation after TBI.
    Type of Medium: Online Resource
    ISSN: 1545-9683 , 1552-6844
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2020
    detail.hit.zdb_id: 2100545-X
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  • 2
    In: Multiple Sclerosis Journal, SAGE Publications, Vol. 24, No. 13 ( 2018-11), p. 1770-1772
    Abstract: The North American Imaging in Multiple Sclerosis (NAIMS) Cooperative represents a network of 27 academic centers focused on accelerating the pace of magnetic resonance imaging (MRI) research in multiple sclerosis (MS) through idea exchange and collaboration. Recently, NAIMS completed its first project evaluating the feasibility of implementation and reproducibility of quantitative MRI measures derived from scanning a single MS patient using a high-resolution 3T protocol at seven sites. The results showed the feasibility of utilizing advanced quantitative MRI measures in multicenter studies and demonstrated the importance of careful standardization of scanning protocols, central image processing, and strategies to account for inter-site variability.
    Type of Medium: Online Resource
    ISSN: 1352-4585 , 1477-0970
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2018
    detail.hit.zdb_id: 2008225-3
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  • 3
    In: Statistical Methods in Medical Research, SAGE Publications, Vol. 29, No. 9 ( 2020-09), p. 2520-2537
    Abstract: Researchers increasingly use meta-analysis to synthesize the results of several studies in order to estimate a common effect. When the outcome variable is continuous, standard meta-analytic approaches assume that the primary studies report the sample mean and standard deviation of the outcome. However, when the outcome is skewed, authors sometimes summarize the data by reporting the sample median and one or both of (i) the minimum and maximum values and (ii) the first and third quartiles, but do not report the mean or standard deviation. To include these studies in meta-analysis, several methods have been developed to estimate the sample mean and standard deviation from the reported summary data. A major limitation of these widely used methods is that they assume that the outcome distribution is normal, which is unlikely to be tenable for studies reporting medians. We propose two novel approaches to estimate the sample mean and standard deviation when data are suspected to be non-normal. Our simulation results and empirical assessments show that the proposed methods often perform better than the existing methods when applied to non-normal data.
    Type of Medium: Online Resource
    ISSN: 0962-2802 , 1477-0334
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2020
    detail.hit.zdb_id: 2001539-2
    detail.hit.zdb_id: 1136948-6
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  • 4
    In: The American Journal of Sports Medicine, SAGE Publications, Vol. 37, No. 10 ( 2009-10), p. 1938-1945
    Abstract: Recent studies have demonstrated predictable healing after arthroscopic rotator cuff repair at a single time point, but few studies have evaluated tendon healing over time. Hypothesis Rotator cuff tears that are intact on ultrasound at 1 time point will remain intact, and clinical results will improve regardless of healing status. Study Design Cohort study; Level of evidence, 3. Methods The Arthroscopic Rotator Cuff Registry was established to determine the effectiveness of arthroscopic rotator cuff repair with clinical outcomes using the American Shoulder and Elbow Surgeons score and ultrasound at 1 and 2 years, postoperatively. Patients were assigned to 1 of 3 groups based on ultrasound appearance: group 1, rotator cuff tendon intact at 1 and 2 years (n = 63); group 2, rotator cuff tendon defect at 1 and 2 years (n = 23); group 3, rotator cuff tendon defect at 1 year but no defect at 2 years (n = 7). Results The ultrasound appearance was consistent at 1 and 2 years for 86 of the 93 patients (92.5%). The patients in group 1 had a significantly lower mean age (57.8 ± 9.8 years) than the patients of group 2 (63.6 ± 8.6 years; P = .04). Group 2 had a significantly greater rotator cuff tear size (4.36 ± 1.6 cm) than group 1 (2.84 ± 1.1 cm; P = .00025). Each group had a significant improvement in American Shoulder and Elbow Surgeons scores from baseline to 2-year follow-up. Conclusion All intact rotator cuff tendons at 1 year remained intact at 2 years. A small group of patients with postoperative imaging did not appear healed by ultrasound at 1 year but did so at 2 years. Patients demonstrated improvement in American Shoulder and Elbow Surgeons shoulder scores, range of motion, and strength, regardless of tendon healing status on ultrasound.
    Type of Medium: Online Resource
    ISSN: 0363-5465 , 1552-3365
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2009
    detail.hit.zdb_id: 2063945-4
    SSG: 31
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  • 5
    Online Resource
    Online Resource
    SAGE Publications ; 2009
    In:  Personality and Social Psychology Bulletin Vol. 35, No. 9 ( 2009-09), p. 1131-1142
    In: Personality and Social Psychology Bulletin, SAGE Publications, Vol. 35, No. 9 ( 2009-09), p. 1131-1142
    Abstract: This article is designed to provide psychologists who publish articles in Personality and Social Psychology Bulletin (PSPB ) with a set of basic issues to consider when reporting their analyses and results. We first assessed the current reporting practices of social and personality psychologists by conducting an analysis of PSPB articles published in the first half of 2007. We evaluated the completeness of these reports with respect to the level of detail in both the Method and Results sections. We then used this information to develop recommendations that we hope will enhance the reporting of quantitative research in social and personality psychology. These suggestions emphasize ways to increase transparency in research reports. Transparency facilitates replication and a critical evaluation of research, thereby promoting scientific progress.
    Type of Medium: Online Resource
    ISSN: 0146-1672 , 1552-7433
    RVK:
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2009
    detail.hit.zdb_id: 2047603-6
    SSG: 5,2
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  • 6
    In: Orthopaedic Journal of Sports Medicine, SAGE Publications, Vol. 2, No. 7_suppl2 ( 2014-07-01), p. 2325967114S0008-
    Abstract: The infrapatellar branch of the saphenous nerve is commonly injured in anterior cruciate ligament reconstruction (ACLR) causing sensory deficits around the knee. The primary purpose of this prospective study was to determine the incidence of patient reported sensory deficits around the knee following ACLR. The secondary purpose was to determine if sensory deficits caused by intraoperative injury present at 6 weeks changed in severity and total area after 6 months and 1 year postoperatively. Methods: Two-hundred and fifty patients that underwent ACLR with or without meniscal repair were prospectively enrolled. Variables for each patient included: type of graft, direction of tibial incision, number of portals, and length of surgical incision. The grafts used were categorized into three types: Allograft (allo), hamstring autograft (HS), or patella tendon autograft (BTB). At 6 weeks, patients completed a questionnaire to ascertain any sensory deficits over their knee. Patients rated their sensory deficit on a scale from 0-10 (“0” = (no deficit) to “10” (complete lack of sensation) and shaded areas on a picture of a knee split into nine rectangular segments (3 by 3 grid) to determine the location of any numbness. Patients completed the same questionnaire at 6 months and 1 year. Any patient that was noted to have no stated numbness at 6 weeks or 6 months was noted to have completed the study. A mixed effects linear regression model was used to identify variables which were predictors for the patient-reported severity of numbness. Results: Overall, 67/221 (30.3%) patients who underwent ACLR stated that they had no numbness at 6 weeks. Of those patients who reported numbness at 6 weeks, 16.6% (25/151) considered their numbness completely resolved by six months. At 1 year, 73.2% (90/123) reported their numbness had gotten better and 14.2% (18/123) considered their numbness resolved. The most common location of numbness was along the inferolateral aspect of the knee. The mean numbness rating for allografts was 2.73 +/- 0.32 (mean +/- standard error) at 6 weeks, decreasing to 1.04 +/- 0.26 at 6 months and 0.64 +/- 0.26 at 1 year for oblique and vertical incisions combined. A statistical model, controlling for time and incision direction, indicated that HS patients were 1.94 +/- 0.52 points higher than allograft patients across all time points, and BTB patients were 1.57 +/- 0.51 points higher than allo. However, there were no significant difference in mean numbness score between BTB and HS patients (p=0.521). Time had a negative impact on the patient reported severity of numbness score for all graft types. At 6 months this effect was -0.95 +/- 0.17 and at 1 year, -1.21 +/- 0.18. The use of BTB increased the mean numbness of affected segments by 0.67 +/- 0.23, while the use of a HS increased the mean numbness of segments by 0.39 +/- 0.21. The mean number of segments decreased slightly with time, down by 0.20 +/- 0.08 at 6 months (p=0.008) and 0.28+- 0.08 at 1 year (p= 〈 0.001). Conclusion: Sensory deficits after ACLR follow the direction of the infrapatellar branch of the saphenous nerve. Patients who underwent ACLR with allo were less likely to develop sensory deficits compared to BTB or HS. Sensory deficits in allo patients were on average, less severe. Surprisingly, there was no significant difference in numbness between HS and BTB grafts. Surgeons should counsel their patients that sensory deficits are common postoperatively after ACLR, but that this sensory disturbance is likely to dissipate with time.
    Type of Medium: Online Resource
    ISSN: 2325-9671 , 2325-9671
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2014
    detail.hit.zdb_id: 2706251-X
    SSG: 31
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  • 7
    In: Medical Decision Making, SAGE Publications, Vol. 40, No. 3 ( 2020-04), p. 289-301
    Abstract: Background. Despite demonstrated efficacy, patient decision aids (DAs) are rarely used in clinical practice in the absence of coverage mandates. Deciding whether to pursue a left ventricular assist device (LVAD) is a major, preference-sensitive decision—ideal for exploring implementation of a DA. Methods. We conducted a type II effectiveness-implementation hybrid trial at 6 LVAD programs using a stepped-wedge cluster-randomized design. Using the RE-AIM framework, we collected both quantitative and qualitative outcomes, including a checklist collected by study staff for each enrolled patient regarding DA use and interviews with LVAD program clinicians preintervention, 6 months postintervention, and at the conclusion of the study. Results. From June 2015 to January 2017, 248 patients and their caregivers were enrolled. A total of 69 interviews were conducted with 48 clinicians at 3 time points. The DA reached 95% of eligible patients. Adoption was 100%, as all sites approached agreed to participate in the trial. Interviews revealed several themes related to the implementation of the DA: clinicians had a strong desire to ensure patients were informed and embraced the DA. Despite this, they reported communication challenges among their team that impeded implementation. Five of the 6 sites have maintained use of the DA following the trial; 1 site reported concerns about decreased procedural volume with use of the DA as a reason for discontinuation. Conclusions. In this hybrid trial, a DA for patients considering LVADs and their caregivers demonstrated high reach. Adoption and implementation were facilitated by a strong desire to ensure that patients were well informed. Future dissemination research and practice should attend to concerns about procedure volume and coverage mandates and facilitate ongoing communication at sites using the DA.
    Type of Medium: Online Resource
    ISSN: 0272-989X , 1552-681X
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2020
    detail.hit.zdb_id: 2040405-0
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  • 8
    In: The Canadian Journal of Psychiatry, SAGE Publications, ( 2019-05-26), p. 070674371984742-
    Abstract: Nightmares are relatively common in patients experiencing psychosis but rarely assessed or treated. Nightmares may maintain persecutory delusions by portraying fears in sensory-rich detail. We tested the potential benefits of imagery-focused cognitive behavioural therapy (CBT) for nightmares on nightmare severity and persecutory delusions. Method: This assessor-blind parallel-group pilot trial randomized 24 participants with nightmares and persecutory delusions to receive CBT for nightmares delivered over 4 weeks in addition to treatment as usual (TAU) or TAU alone. Assessments were at 0, 4 (end of treatment), and 8 weeks (follow-up). Feasibility outcomes assessed therapy uptake, techniques used, satisfaction, and attrition. The primary efficacy outcome assessed nightmare severity at week 4. Analyses were intention to treat, estimating treatment effect with 95% confidence intervals (CIs). Results: All participants offered CBT completed therapy (mean [SD], 4.8 [0.6] sessions) with high satisfaction, and 20 (83%) participants completed all assessments. Compared with TAU, CBT led to large improvements in nightmares (adjusted mean difference = −7.0; 95% CI, –12.6 to –1.3; d = –1.1) and insomnia (6.3; 95% CI, 2.6 to 10.0; d = 1.4) at week 4. Gains were maintained at follow-up. Suicidal ideation was not exacerbated by CBT but remained stable to follow-up, compared with TAU, which reduced at follow-up (6.8; 95% CI, 0.3 to 3.3; d = 0.7). CBT led to reductions in paranoia (–20.8; 95% CI, –43.2 to 1.7; d = –0.6), although CIs were wide. Three serious adverse events were deemed unrelated to participation (CBT = 2, TAU = 1). Conclusions: CBT for nightmares is feasible and may be efficacious for treating nightmares and comorbid insomnia for patients with persecutory delusions. It shows promise on paranoia but potentially not on suicidal ideation.
    Type of Medium: Online Resource
    ISSN: 0706-7437 , 1497-0015
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2019
    detail.hit.zdb_id: 2035338-8
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  • 9
    Online Resource
    Online Resource
    SAGE Publications ; 1995
    In:  Proceedings of the Human Factors and Ergonomics Society Annual Meeting Vol. 39, No. 1 ( 1995-10), p. 98-102
    In: Proceedings of the Human Factors and Ergonomics Society Annual Meeting, SAGE Publications, Vol. 39, No. 1 ( 1995-10), p. 98-102
    Abstract: There is a real possibility that the air traffic control system in the United States will change radically in the next decade. One vision–“free flight” or “free routing”–is to move most of the responsibility for navigation and separation back to the cockpit and away from ground based air traffic systems. The basic notion of free flight is that each flight would be completely determined by the user, i.e. by some form of airline/pilot combination, and would not need to follow pre-defined airways or altitudes. The airlines would inform the air traffic system of each aircraft's intentions, but would not have to seek any prior air traffic approval. The job of the air traffic system would be to meet the user's requirements, but not to suggest what those requirements should be. However, the air traffic system would be expected to collaborate with the airlines to ensure the safe passage of flights and to intervene when aircraft separation requirements are jeopardized or violated. Such a system would bring with it dramatic changes in the roles of all the human members of the aviation system, and as such, would have significant human factors impacts. The goal of this panel will be to identify and discuss some of those issues.
    Type of Medium: Online Resource
    ISSN: 2169-5067 , 1071-1813
    Language: English
    Publisher: SAGE Publications
    Publication Date: 1995
    detail.hit.zdb_id: 2415770-3
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  • 10
    Online Resource
    Online Resource
    SAGE Publications ; 2007
    In:  Homicide Studies Vol. 11, No. 3 ( 2007-08), p. 231-237
    In: Homicide Studies, SAGE Publications, Vol. 11, No. 3 ( 2007-08), p. 231-237
    Abstract: Using a sample of siblicides committed in Chicago from 1870 through 1930, the authors tested two predictions heuristically guided by an evolutionary perspective. They predicted a greater proportion of siblicides of in-law siblings will be perpetrated by beatings, relative to the proportion of siblicides of full siblings. This difference did not reach statistical significance although it was in the predicted direction. They found, as predicted, that a significantly greater proportion of accidental deaths occurred with siblicides of full siblings relative to the proportion of siblicides of in-law siblings. Discussion addresses limitations of this research and the need for a national-level database that codes for the genetic relationship between the siblicide victim and offender to capitalize on greater statistical power.
    Type of Medium: Online Resource
    ISSN: 1088-7679 , 1552-6720
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2007
    detail.hit.zdb_id: 2034461-2
    SSG: 2
    SSG: 2,1
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