In:
Natural Product Communications, SAGE Publications, Vol. 14, No. 7 ( 2019-07), p. 1934578X1986350-
Kurzfassung:
Three monoterpene glucosides were isolated from the flowers of Brugmansia arborea L. using repeated silica gel and octadecyl SiO 2 column chromatography. Based on spectroscopic data including 1d-NMR ( 1 H, 13 C, and distortionless enhancement by polarization transfer (DEPT)), 2D-NMR (gradient correlation spectroscopy (gCOSY), gradient heteronuclear single quantum coherence (gHSQC), and gradient heteronuclear multiple bond coherence (gHMBC)), Infrared Spectroscophy, and Mass Spectroscophy, the glucosides were identified as citronellol O- β-D-glucopyranoside (1), jasminoside N (2), and jasminoside P (3). The EtOAc ( Brugmansia arborea Flowers ethyl acetate fraction [BAFE] ) and n-BuOH ( Brugmansia arborea Flowers n-butanol fraction [BAFB]) fractions showed high inhibition of tyrosinase activity (BAFE: IC 50 = 68.0 and BAFB: IC 50 = 59.3 μg/mL), and all isolated monoterpenes inhibited tyrosinase activity (1: IC 50 = 156.5, 2: IC 50 = 198.2, and 3: IC 50 = 191.0 μM).
Materialart:
Online-Ressource
ISSN:
1934-578X
,
1555-9475
DOI:
10.1177/1934578X19863503
Sprache:
Englisch
Verlag:
SAGE Publications
Publikationsdatum:
2019
ZDB Id:
2430442-6
SSG:
15,3
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